Abstract:
:Mutations that are beneficial in one environment can have different fitness effects in other environments. In the context of antibiotic resistance, the resulting genotype-by-environment interactions potentially make selection on resistance unpredictable in heterogeneous environments. Furthermore, resistant bacteria frequently fix additional mutations during evolution in the absence of antibiotics. How do these two types of mutations interact to determine the bacterial phenotype across different environments? To address this, I used Escherichia coli as a model system, measuring the effects of nine different rifampicin resistance mutations on bacterial growth in 31 antibiotic-free environments. I did this both before and after approximately 200 generations of experimental evolution in antibiotic-free conditions (LB medium), and did the same for the antibiotic-sensitive wild type after adaptation to the same environment. The following results were observed: (i) bacteria with and without costly resistance mutations adapted to experimental conditions and reached similar levels of competitive fitness; (ii) rifampicin resistance mutations and adaptation to LB both indirectly altered growth in other environments; and (iii) resistant-evolved genotypes were more phenotypically different from the ancestor and from each other than resistant-nonevolved and sensitive-evolved genotypes. This suggests genotype-by-environment interactions generated by antibiotic resistance mutations, observed previously in short-term experiments, are more pronounced after adaptation to other types of environmental variation, making it difficult to predict long-term selection on resistance mutations from fitness effects in a single environment.
journal_name
J Evol Bioljournal_title
Journal of evolutionary biologyauthors
Hall ARdoi
10.1111/jeb.12172subject
Has Abstractpub_date
2013-08-01 00:00:00pages
1655-64issue
8eissn
1010-061Xissn
1420-9101journal_volume
26pub_type
杂志文章abstract::Maternal effects on progeny wing size and shape in a homozygous parthenogenetic strain of Drosophila mercatorum were investigated. The impact of external maternal factors (heat stress) and the impact of internal maternal factors (different maternal and grand maternal age) were studied. The offspring developed under id...
journal_title:Journal of evolutionary biology
pub_type: 杂志文章
doi:10.1111/j.1420-9101.2005.00955.x
更新日期:2005-07-01 00:00:00
abstract::Assessing processes of geographic expansion in contact zones is a crucial step towards an accurate prediction of the evolution of species genetic diversity. The geographic distribution of cytonuclear discordance often reflects genetic introgression patterns across a species geographic range. Antirrhinum majus pseudoma...
journal_title:Journal of evolutionary biology
pub_type: 杂志文章
doi:10.1111/j.1420-9101.2011.02276.x
更新日期:2011-07-01 00:00:00
abstract::Pathogens are thought to exert strong selection on their hosts leading to increased host resistance. Bacillus thuringiensis kurstaki (Bkt) is a ubiquitous entomopathogen that has become the mainstay of nonchemical control of Lepidopteran pests and thus, the potential exists for the evolution of resistance in targeted ...
journal_title:Journal of evolutionary biology
pub_type: 杂志文章
doi:10.1111/j.1420-9101.2006.01232.x
更新日期:2007-01-01 00:00:00
abstract::We use an individual-based simulation model to investigate factors influencing progress toward ecological speciation. We find that environmental differences can quickly lead to the evolution of substantial reproductive barriers between a population colonizing a new environment and the ancestral population in the old e...
journal_title:Journal of evolutionary biology
pub_type: 杂志文章
doi:10.1111/j.1420-9101.2008.01627.x
更新日期:2009-01-01 00:00:00
abstract::One explanation for hybridization between species is the fitness benefits it occasionally confers to the hybridizing individuals. This explanation is possible in species that have evolved alternative male reproductive tactics: individuals with inferior tactics might be more prone to hybridization provided it increases...
journal_title:Journal of evolutionary biology
pub_type: 杂志文章
doi:10.1111/j.1420-9101.2009.01870.x
更新日期:2009-12-01 00:00:00
abstract::Post-meiotic sperm ageing, both before ejaculation and after ejaculation, has been shown to negatively affect offspring fitness by lowering the rate of embryonic development, reducing embryonic viability and decreasing offspring condition. These negative effects are thought to be caused by intrinsic factors such as ox...
journal_title:Journal of evolutionary biology
pub_type: 杂志文章
doi:10.1111/jeb.13590
更新日期:2020-05-01 00:00:00
abstract::Ecologically important traits of insects are often affected by facultative bacterial endosymbionts. This is best studied in the pea aphid Acyrthosiphon pisum, which is frequently infected by one or more of eight facultative symbiont species. Many of these symbiont species have been shown to provide one ecological bene...
journal_title:Journal of evolutionary biology
pub_type: 杂志文章
doi:10.1111/jeb.12705
更新日期:2015-10-01 00:00:00
abstract::Sexually selected traits are limited by selection against those traits in other fitness components, such as survival. Thus, sexual selection favouring large size in males should be balanced by higher mortality of larger males. However, evidence from red-winged blackbirds (Agelaius phoeniceus) indicates that large male...
journal_title:Journal of evolutionary biology
pub_type: 杂志文章
doi:10.1046/j.1420-9101.2003.00479.x
更新日期:2003-01-01 00:00:00
abstract::Vertebrates commonly use carotenoid-based traits as social signals. These can reliably advertise current nutritional status and health because carotenoids must be acquired through the diet and their allocation to ornaments is traded-off against other self-maintenance needs. We propose that the coloration more generall...
journal_title:Journal of evolutionary biology
pub_type: 杂志文章
doi:10.1111/j.1420-9101.2009.01926.x
更新日期:2010-03-01 00:00:00
abstract::The evolutionary mechanisms underlying the maintenance of invariant traits are poorly understood, partly because the lack of variance makes these mechanisms difficult to study. Although the number of cotyledons that plant species produce is highly canalized, populations of plants frequently contain individuals with ab...
journal_title:Journal of evolutionary biology
pub_type: 杂志文章
doi:10.1111/j.1420-9101.2004.00821.x
更新日期:2005-01-01 00:00:00
abstract::The achaete-scute complex (AS-C) has been a useful paradigm for the study of pattern formation and its evolution. achaete-scute genes have duplicated and evolved distinct expression patterns during the evolution of cyclorraphous Diptera. Are the expression patterns in different species driven by conserved regulatory e...
journal_title:Journal of evolutionary biology
pub_type: 杂志文章
doi:10.1111/jeb.12687
更新日期:2015-10-01 00:00:00
abstract::Which conditions favour the evolution of hermaphroditism or separate sexes? One classical hypothesis states that an organism's mode of locomotion (if any) when searching for a mate should influence breeding system evolution. We used published phylogenies to reconstruct evolutionary changes in adult mate-search efficie...
journal_title:Journal of evolutionary biology
pub_type: 杂志文章
doi:10.1111/j.1420-9101.2008.01524.x
更新日期:2008-05-01 00:00:00
abstract::Phenotypes are the target of selection and affect the ability of organisms to persist in variable environments. Phenotypes can be influenced directly by genes and/or by phenotypic plasticity. The amphibian-killing fungus Batrachochytrium dendrobatidis (Bd) has a global distribution, unusually broad host range, and hig...
journal_title:Journal of evolutionary biology
pub_type: 杂志文章
doi:10.1111/jeb.13413
更新日期:2019-03-01 00:00:00
abstract::Mutagenic and epigenetic effects of environmental stressors and their transgenerational consequences are of interest to evolutionary biologists because they can amplify natural genetic variation. We studied the effect of parental exposure to radioactive contamination on offspring development in lesser marsh grasshoppe...
journal_title:Journal of evolutionary biology
pub_type: 杂志文章
doi:10.1111/j.1420-9101.2012.02502.x
更新日期:2012-06-01 00:00:00
abstract::Island races of passerine birds display repeated evolution towards larger body size compared with their continental ancestors. The Capricorn silvereye (Zosterops lateralis chlorocephalus) has become up to six phenotypic standard deviations bigger in several morphological measures since colonization of an island approx...
journal_title:Journal of evolutionary biology
pub_type: 杂志文章
doi:10.1111/j.1420-9101.2006.01242.x
更新日期:2007-03-01 00:00:00
abstract::Sexual selection has been suggested to be an important driver of speciation in cichlid fishes of the Great Lakes of Africa, and the presence of male egg dummies is proposed to have played a key role. Here, we investigate how mouthbrooding and egg dummies have evolved in Tanganyikan cichlids, the lineage which seeded t...
journal_title:Journal of evolutionary biology
pub_type: 杂志文章
doi:10.1111/jeb.12231
更新日期:2013-11-01 00:00:00
abstract::Although Trinidadian populations of the guppy, Poecilia reticulata, show considerable adaptive genetic differentiation, they have been assumed to show little or no reproductive isolation. We tested this assumption by crossing Caroni (Tacarigua River) and Oropuche (Oropuche R.) drainage populations from Trinidad's Nort...
journal_title:Journal of evolutionary biology
pub_type: 杂志文章
doi:10.1111/j.1420-9101.2005.01069.x
更新日期:2006-07-01 00:00:00
abstract::Knowledge on interspecific pre- and post-zygotic isolation mechanisms provides insights into speciation patterns. Using crosses (F(1) and backcrosses) of two closely related flea beetles species, Altica fragariae and A. viridicyanea, specialized on different hosts in sympatry, we measured: (a) the type of reproductive...
journal_title:Journal of evolutionary biology
pub_type: 杂志文章
doi:10.1111/j.1420-9101.2009.01841.x
更新日期:2009-11-01 00:00:00
abstract::The North Pacific Ocean has been of great significance to understanding biogeography and speciation in temperate faunas, including for two species of char (Salmonidae: Salvelinus) whose evolutionary relationship has been controversial. We examined the morphology and genetics (microsatellite and mitochondrial DNA) of A...
journal_title:Journal of evolutionary biology
pub_type: 杂志文章
doi:10.1111/j.1420-9101.2008.01603.x
更新日期:2008-11-01 00:00:00
abstract::Density dependence in vital rates is a key feature affecting temporal fluctuations of natural populations. This has important implications for the rate of random genetic drift. Mating systems also greatly affect effective population sizes, but knowledge of how mating system and density regulation interact to affect ra...
journal_title:Journal of evolutionary biology
pub_type: 杂志文章
doi:10.1111/jeb.13126
更新日期:2017-08-01 00:00:00
abstract::Temporal resource fluctuations could affect the strength of antagonistic coevolution through population dynamics and costs of adaptation. We studied this by coevolving the prey bacterium Serratia marcescens with the predatory protozoa Tetrahymena thermophila in constant and pulsed-resource environments for approximate...
journal_title:Journal of evolutionary biology
pub_type: 杂志文章
doi:10.1111/j.1420-9101.2011.02379.x
更新日期:2011-12-01 00:00:00
abstract::Because pollinators are unable to directly assess the amount of rewards offered by flowers, they rely on the information provided by advertising floral traits. Thus, having a lower intra-individual correlation between signal and reward (signal accuracy) than other plants in the population provides the opportunity to r...
journal_title:Journal of evolutionary biology
pub_type: 杂志文章
doi:10.1111/j.1420-9101.2010.02132.x
更新日期:2010-12-01 00:00:00
abstract::Recent contributions from DNA sequences have revolutionized our concept of systematic relationships in angiosperms. However, parts of the angiosperm tree remain unclear. Previous studies have been based on coding or rDNA regions of relatively conserved genes. A phylogeny for basal angiosperms based on noncoding, fast-...
journal_title:Journal of evolutionary biology
pub_type: 杂志文章
doi:10.1046/j.1420-9101.2003.00577.x
更新日期:2003-07-01 00:00:00
abstract::Viviparity, the bearing of live young, has evolved well over 100 times among squamate reptiles. This reproductive strategy is hypothesized to allow maternal control of the foetus' thermal environment and thereby to increase the fitness of the parents and offspring. Two hypotheses have been posited to explain this phen...
journal_title:Journal of evolutionary biology
pub_type: 杂志文章
doi:10.1111/jeb.12536
更新日期:2014-12-01 00:00:00
abstract::A recent model studies the evolution of cooperation on a network, and concludes with a result connecting the benefits and costs of interactions and the number of neighbours. Here, an inclusive fitness analysis is conducted of the only case solved analytically, of a cycle, and the identical result is obtained. This bri...
journal_title:Journal of evolutionary biology
pub_type: 杂志文章
doi:10.1111/j.1420-9101.2007.01413.x
更新日期:2007-11-01 00:00:00
abstract::Many forms of reproductive isolation contribute to speciation, and early-acting barriers may be especially important, because they have the first opportunity to limit gene flow. Ecogeographic isolation occurs when intrinsic traits of taxa contribute to disjunct geographic distributions, reducing the frequency of inter...
journal_title:Journal of evolutionary biology
pub_type: 杂志文章
doi:10.1111/jeb.13442
更新日期:2019-06-01 00:00:00
abstract::Ecological speciation occurs when populations evolve reproductive isolation as a result of divergent natural selection. This isolation can be influenced by many potential reproductive barriers, including selection against hybrids, selection against migrants and assortative mating. How and when these barriers act and i...
journal_title:Journal of evolutionary biology
pub_type: 杂志文章
doi:10.1111/jeb.12978
更新日期:2016-12-01 00:00:00
abstract::Habitats are spatially and temporally variable, and organisms must be able to track these changes. One potential mechanism for this is dispersal by flight. Therefore, we would expect flying animals to show adaptations in wing shape related to habitat variation. In this work, we explored variation in wing shape in rela...
journal_title:Journal of evolutionary biology
pub_type: 杂志文章
doi:10.1111/jeb.12203
更新日期:2013-09-01 00:00:00
abstract::Co-inheritance in life-history traits may result in unpredictable evolutionary trajectories if not accounted for in life-history models. Iteroparity (the reproductive strategy of reproducing more than once) in Atlantic salmon (Salmo salar) is a fitness trait with substantial variation within and among populations. In ...
journal_title:Journal of evolutionary biology
pub_type: 杂志文章
doi:10.1111/jeb.13418
更新日期:2019-04-01 00:00:00
abstract::It has been suggested that polyandry allows females to increase offspring genetic diversity and reduce the prevalence and susceptibility of their offspring to infectious diseases. We tested this hypothesis in wild-derived house mice (Mus musculus) by experimentally infecting the offspring from 15 single- and 15 multip...
journal_title:Journal of evolutionary biology
pub_type: 杂志文章
doi:10.1111/jeb.12854
更新日期:2016-06-01 00:00:00