Abstract：
PURPOSE:Heterotopic ossification is a common complication after total hip arthroplasty. Non-steroidal anti-inflammatory drugs (NSAIDs) are known to prevent heterotopic ossifications effectively, however gastrointestinal complaints are reported frequently. In this study, we investigated whether etoricoxib, a selective cyclo-oxygenase-2 (COX-2) inhibitor that produces fewer gastrointestinal side effects, is an effective alternative for the prevention of heterotopic ossification. METHODS:We investigated the effectiveness of oral etoricoxib 90 mg for seven days in a prospective two-stage study design for phase-2 clinical trials in a small sample of patients (n = 42). A cemented primary total hip arthroplasty was implanted for osteoarthritis. Six months after surgery, heterotopic ossification was determined on anteroposterior pelvic radiographs using the Brooker classification. RESULTS:No heterotopic ossification was found in 62 % of the patients that took etoricoxib; 31 % of the patients had Brooker grade 1 and 7 % Brooker grade 2 ossification. CONCLUSIONS:Etoricoxib seems effective in preventing heterotopic ossification after total hip arthroplasty. This finding further supports the use of COX-2 inhibitors for the prevention of heterotopic ossification following total hip arthroplasty.
journal_name
Int Orthopjournal_title
International orthopaedicsauthors
Brunnekreef JJ,Hoogervorst P,Ploegmakers MJ,Rijnen WH,Schreurs BWdoi
10.1007/s00264-013-1781-0subject
Has Abstractpub_date
2013-04-01 00:00:00pages
583-7issue
4eissn
0341-2695issn
1432-5195journal_volume
37pub_type
杂志文章abstract：PURPOSE:There remains controversy as to whether computer-navigated total knee replacement (TKR) improves the overall prosthesis alignment and patient function. The aim of this study was to determine whether computer-assisted total knee arthroplasty provides superior prosthesis positioning when compared to a conventiona...
journal_title：International orthopaedics
pub_type： 杂志文章,随机对照试验
doi：10.1007/s00264-013-1996-0
更新日期：2014-02-01 00:00:00
abstract：PURPOSE:The study aims to analyze the incidence of 30-day mortality in elderly patients who underwent surgery for hip fractures and its associated factors. METHODS:A prospective multicentric study was performed. All patients aged ≥ 65 years, with fragility hip fractures, consecutively admitted in two Italian hospitals...
journal_title：International orthopaedics
pub_type： 杂志文章
doi：10.1007/s00264-018-4057-x
更新日期：2019-02-01 00:00:00
abstract：PURPOSE:The aim of this meta-analysis was to compare the results of arthroscopic single-bundle and double-bundle anterior cruciate ligament (ACL) reconstruction. METHODS:We systematically searched electronic databases to identify randomised controlled trials (RCTs) in which arthroscopic single-bundle was compared with...
journal_title：International orthopaedics
pub_type： 杂志文章,meta分析,评审
doi：10.1007/s00264-012-1651-1
更新日期：2013-02-01 00:00:00
abstract：:Twenty-one patients having proximal ulna nonunion were treated with contoured plating. The most proximal hole received an intramedullary 6.5-mm cancellous lag screw that extends fixation of the nonunion site. Mean age of the patients was 41.7 years. Average follow-up period was 22 months. Union occurred in 19 cases af...
journal_title：International orthopaedics
pub_type： 临床试验,杂志文章
doi：10.1007/s00264-009-0809-y
更新日期：2010-03-01 00:00:00
abstract：:In 1975 we carried out a survey in Hong Kong to locate Chinese children with congenital dislocation of the hip. Analysis of the available records between 1960 and 1975 gave an observed incidence which was at least 10 times less than found in Caucasians. The age and sex distribution, radiographic findings and the left-...
journal_title：International orthopaedics
pub_type： 杂志文章
doi：10.1007/BF00266064
更新日期：1981-01-01 00:00:00
abstract：:Fifty-four consecutive acute Achilles tendon ruptures were treated with end-to-end suture augmented with gastrocnemius fascial flaps. Surgery was performed within 24 h. Mean patient age was 35 (23-57) years, and 46 were men. Mean follow-up time was 4.8 (2-8) years. At follow-up, the mean visual analogue scale for pain...
journal_title：International orthopaedics
pub_type： 杂志文章
doi：10.1007/s00264-004-0598-2
更新日期：2005-02-01 00:00:00
abstract：PURPOSE:The aim of this study was to map the strength distribution of the human patella and correlate it to the subchondral bone plate density obtained by means of computed tomographyosteoabsorptiometry (CT-OAM). METHODS:Measurements were performed at 34 standardized points on each patella. The mineralization patterns...
journal_title：International orthopaedics
pub_type： 杂志文章
doi：10.1007/s00264-012-1545-2
更新日期：2012-09-01 00:00:00
abstract：:In 16 patients with ulnar wrist pain, we performed primary arthroscopic or open repair of the peripheral rim tears of the triangular fibrocartilage complex (TFCC) (14 ulnar, 4 volar, and 3 radial tears). The wrist function was assessed before and 1 year after the repair using the Mayo-modified wrist score. The average...
journal_title：International orthopaedics
pub_type： 杂志文章
doi：10.1007/s002640100285
更新日期：2001-01-01 00:00:00
abstract：PURPOSE:To compare the radiological and clinical outcomes of interlocking nail (ILN) and locking plate fixation (LCP) for humeral shaft fractures. METHODS:A total of 63 patients with displaced humeral shaft fractures between October 2014 and January 2017 were evaluated prospectively. They were divided randomly into tw...
journal_title：International orthopaedics
pub_type： 杂志文章
doi：10.1007/s00264-020-04696-6
更新日期：2020-10-01 00:00:00
abstract：PURPOSE:The review aims to provide a summary of the current literature regarding common medications prescribed in orthopaedic surgery and their potential implications in COVID-19 patients. METHODS:A systematic review was performed using the PRISMA guidelines. All clinical studies, reviews, consensus and guidelines rel...
journal_title：International orthopaedics
pub_type： 杂志文章
doi：10.1007/s00264-020-04643-5
更新日期：2020-08-01 00:00:00
abstract：:We report three cases of para-articular chondroma and osteochondroma in the region of infrapatellar fat pad. All three lesions were resected and examined histologically. Two of them were primarily cartilaginous with a lobular pattern internally, and one uniformly osseous with peripheral cartilage. We conclude that the...
journal_title：International orthopaedics
pub_type： 杂志文章
doi：10.1007/s002640050322
更新日期：1999-01-01 00:00:00
abstract：:We describe a hemiarthroplasty of the shoulder with an acrylic Judet hip prosthesis, inserted after the excision of a giant cell tumour of the head of the humerus, which functioned well for 39 years. ...
journal_title：International orthopaedics
pub_type： 杂志文章
doi：
更新日期：1997-01-01 00:00:00
abstract：PURPOSE:Acute compartment syndrome is a condition whereby tissue ischaemia occurs due to increased pressure in a closed myofascial compartment. It is a surgical emergency, with rapid recognition and treatment-the keys to good outcomes. METHODS:The available literature on diagnostic aids was reviewed by one of the seni...
journal_title：International orthopaedics
pub_type： 杂志文章,评审
doi：10.1007/s00264-019-04386-y
更新日期：2019-11-01 00:00:00
abstract：:Five cases of fracture of the lateral tibial condyle of the split-depression type were treated by elevation of the depressed fragment, bone grafting and cancellous bone screws. During the operation, tantalum markers were inserted into the depressed fragment and the tibial metaphysis for radiographic stereophotogrammet...
journal_title：International orthopaedics
pub_type： 杂志文章
doi：10.1007/BF00192467
更新日期：1994-06-01 00:00:00
abstract：PURPOSE:Knee pain after total knee arthroplasty may be caused by an unresurfaced patella. Secondary isolated resurfacing of the previously unresurfaced patella in total knee arthroplasty remains controversial. The aim of this retrospective study was to evaluate the outcome after patellar resurfacing as a second stage p...
journal_title：International orthopaedics
pub_type： 杂志文章
doi：10.1007/s00264-011-1463-8
更新日期：2012-06-01 00:00:00
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journal_title：International orthopaedics
pub_type： 杂志文章
doi：10.1007/s00264-017-3561-8
更新日期：2017-10-01 00:00:00
abstract：PURPOSE:Coracoclavicular joint (CCJ) is a rare anomalous joint occasionally found between the coracoid process of scapula and the conoid tubercle of clavicle. The articulation has been extensively studied by means of anatomical, osteological and radiological investigations. Most cases are discovered incidentally, with ...
journal_title：International orthopaedics
pub_type： 杂志文章,评审
doi：10.1007/s00264-011-1309-4
更新日期：2011-12-01 00:00:00
abstract：AIMS:This study was aimed to study the arthrodesis of the first metatarsophalangeal joint using an oblique interfragmentary lag screw and dorsal plate as an effective option for the treatment of hallux rigidus. Few researchers have studied the outcome of this surgical method over a long follow-up period. PATIENTS AND ...
journal_title：International orthopaedics
pub_type： 杂志文章
doi：10.1007/s00264-016-3277-1
更新日期：2016-11-01 00:00:00
abstract：:We followed prospectively 27 patients with severe acetabular bone-stock deficiencies due to developmental dysplasia of the hip. Mean preoperative patient age was 56 (34-78) years, mean Harris hip score was 31 (16-66) points and pre-operative mean acetabular angle of Sharp was 47 degrees (34 degrees - 61 degrees). Oper...
journal_title：International orthopaedics
pub_type： 杂志文章
doi：10.1007/s00264-004-0559-9
更新日期：2004-08-01 00:00:00
abstract：PURPOSE:Management of proximal humeral tumours remains a surgical challenge. No study to date has assessed the quality of life scores following the composite reverse shoulder arthroplasty for this indication. We, therefore, evaluated function and quality of life following reconstruction with allograft for malignant tum...
journal_title：International orthopaedics
pub_type： 杂志文章
doi：10.1007/s00264-017-3538-7
更新日期：2017-12-01 00:00:00
abstract：:Seventy-four cases of tuberculosis of the upper limb joints (sterno-clavicular 1; shoulder 12; elbow 42; wrist 10 and fingers 9), treated by two of the authors, were reviewed. Eighty-seven percent presented at an advanced stage of destruction. The diagnosis was proved in 71 our of 74 cases. In most, the treatment was ...
journal_title：International orthopaedics
pub_type： 杂志文章
doi：10.1007/BF00266268
更新日期：1986-01-01 00:00:00
abstract：:A case of bilateral habitual dislocation of the patella associated with cleft lip and palate, and short metatarsals, metacarpals and phalanges is reported. The possible cause of habitual dislocation is discussed in the light of 20 cases which have been seen by the author. ...
journal_title：International orthopaedics
pub_type： 杂志文章
doi：10.1007/BF00183358
更新日期：1990-01-01 00:00:00
abstract：:The aim of this study was to compare the safety and efficacy of OsteoSet®2 DBM with autologous cancellous bone in free vascularised fibular grafting for the treatment of large osteonecrotic lesions of the femoral head. Twenty-four patients (30 hips) with large osteonecrotic lesions of the femoral head (stage IIC in si...
journal_title：International orthopaedics
pub_type： 杂志文章
doi：10.1007/s00264-009-0915-x
更新日期：2011-04-01 00:00:00
abstract：:Pure alumina ceramic has been in clinical use in orthopaedics since 1971 and, currently, up to 5 million components have been implanted. Alumina offers advantages like stability, biocompatibility and low wear; however, it has limited strength. Applications are limited by design considerations. Engineers in biomaterial...
journal_title：International orthopaedics
pub_type： 杂志文章,评审
doi：10.1007/s00264-007-0484-9
更新日期：2009-04-01 00:00:00
abstract：PURPOSE:Occult intra-operative periprosthetic acetabular fracture is a seldom-reported complication of primary total hip arthroplasty (THA). It may potentially be associated with cup instability and implant loosening. The present study aimed to investigate clinical consequences of this complication. METHODS:Between 20...
journal_title：International orthopaedics
pub_type： 杂志文章
doi：10.1007/s00264-018-4084-7
更新日期：2019-07-01 00:00:00
abstract：PURPOSE:Open reduction and internal fixation (ORIF) using an extended lateral approach combined with plate osteosynthesis represents the current gold standard in calcaneal fracture treatment, but it is associated with a wound complication rate of up to 30%. Literature suggests that micro-circulation is one of the key f...
journal_title：International orthopaedics
pub_type： 杂志文章
doi：10.1007/s00264-018-4031-7
更新日期：2018-11-01 00:00:00
abstract：PURPOSE:Reconstruction of the medial patellofemoral ligament (MPFL) has become a popular procedure for patients with patellofemoral instability. Nevertheless, complication rates of up to 26 % have been reported. This study presents the analysis of failure and clinical outcome of subsequent revision surgery in young pat...
journal_title：International orthopaedics
pub_type： 杂志文章
doi：10.1007/s00264-014-2437-4
更新日期：2014-11-01 00:00:00
abstract：:During a 4-year period, 32 patients with type C unstable sacral fractures were treated in our university hospital. All patients had neurological deficits as a result of their sacral fracture. The average age was 31.2 (range 22-54) years and the average Hannover Polytrauma Score (PTS) was 24 (range 19-40) points. Twelv...
journal_title：International orthopaedics
pub_type： 杂志文章
doi：10.1007/s00264-007-0468-9
更新日期：2009-02-01 00:00:00
abstract：PURPOSE:The present study was designed to address whether osteoblasts play a synergistic role in promoting mesenchymal stem cell (MSC) osteogenesis in a direct cell-cell contact co-culture model. METHODS:Murine C3H10T1/2 and MC3T3-E1 cell lines were mixed and plated onto 12-well culture plates and co-cultured at vario...
journal_title：International orthopaedics
pub_type： 杂志文章
doi：10.1007/s00264-011-1259-x
更新日期：2012-01-01 00:00:00
abstract：:Lower lumbar spinal fusion was carried out in 72 patients by a technique which involved screw fixation of the facet joints. Stability was achieved and mobilisation was allowed immediately. Radiographs after operation showed bony fusion in 94.5%. Pain was diminished and 76% of the patients would undergo the same treatm...
journal_title：International orthopaedics
pub_type： 杂志文章
doi：10.1007/BF00182698
更新日期：1992-01-01 00:00:00
