Abstract：
:Dextromethorphan is a commonly encountered antitussive medication which has found additional therapeutic use in the treatment of pseudobulbar disorder and as an adjunct to opiate use in pain management. Dextromethorphan at high doses has phencyclidine-like effects on the NMDA receptor system; recreational use of high doses has been found to cause mania and hallucinations. The toxicology and pharmacology of the drug in abuse are reviewed, and the historical literature of adverse psychiatric outcomes is assessed. Five new cases of dextromethorphan intoxication that resulted in assault, suicide, and homicide are reported, together with the corresponding toxicology results. Blood concentrations ranged from 300 to 19,000 μg/L. These results are compared with typical concentrations reported in therapeutic use and impaired driving cases. Based on these findings, dextromethorphan should be considered as a potential causative agent in subjects presenting with mania, psychosis, or hallucinations, and abusers are at risk for violent and self-destructive acts.
journal_name
J Forensic Scijournal_title
Journal of forensic sciencesauthors
Logan BK,Yeakel JK,Goldfogel G,Frost MP,Sandstrom G,Wickham DJdoi
10.1111/j.1556-4029.2012.02133.xsubject
Has Abstractpub_date
2012-09-01 00:00:00pages
1388-94issue
5eissn
0022-1198issn
1556-4029journal_volume
57pub_type
杂志文章abstract：:The decomposition of bodies and the decay of associated cultural materials, including clothing, personal ornaments, caskets, and grave goods, was investigated based on a series of exhumations on a small sand island on Kwajalein Atoll, Marshall Islands. Decay data were documented for an interment period between 40 and ...
journal_title：Journal of forensic sciences
pub_type： 杂志文章
doi：
更新日期：1995-05-01 00:00:00
abstract：:A case of homicide and attempted homicide is described. The comparison of tire-marks linked the suspect's vehicle to the scene of crime only with low certainty. However, the comparison of the pressure mark on the hubcap found at the scene, with the balance weight on one of the wheels of the suspect's car, connected th...
journal_title：Journal of forensic sciences
pub_type： 杂志文章
doi：
更新日期：2002-05-01 00:00:00
abstract：:In developing latent prints on cartridge casings and shotgun shells, multiple chemical processes should be used in order to obtain the best results. In Phase I, this study established an optimal chemical sequence for both Brass and Nickel cartridge casings based on six sequences involving four chemicals: Cyanoacrylate...
journal_title：Journal of forensic sciences
pub_type： 杂志文章
doi：10.1111/j.1556-4029.2009.01152.x
更新日期：2009-11-01 00:00:00
abstract：:The techniques described above have been found to provide a rapid method of human skeletal preparation, with advantages of speed and applicability to fresh, fixed, or partially decomposed skeletal materials. While other techniques which can be used include the traditional use of Dermestidae beetle colonies, a five-st...
journal_title：Journal of forensic sciences
pub_type： 杂志文章
doi：
更新日期：1975-07-01 00:00:00
abstract：:The paper is concerned with the strength of DNA evidence when a suspect is identified via a search through a database of the DNA profiles of known individuals. Consideration of the appropriate likelihood ratio shows that in this setting the DNA evidence is (slightly) stronger than when a suspect is identified by other...
journal_title：Journal of forensic sciences
pub_type： 杂志文章
doi：
更新日期：1996-07-01 00:00:00
abstract：:In today's society, human cannibalism is extremely rare and represents an unthinkable act of violence. Scientific literature on the topic is sparse due to significant methodological problems, such as collecting enough data and generating unbiased analyses. The purpose of this article is to illustrate some psychodynami...
journal_title：Journal of forensic sciences
pub_type： 杂志文章,评审
doi：10.1111/1556-4029.14099
更新日期：2019-09-01 00:00:00
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journal_title：Journal of forensic sciences
pub_type： 杂志文章
doi：
更新日期：1989-07-01 00:00:00
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journal_title：Journal of forensic sciences
pub_type： 杂志文章
doi：
更新日期：1987-07-01 00:00:00
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journal_title：Journal of forensic sciences
pub_type： 杂志文章
doi：
更新日期：2002-09-01 00:00:00
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journal_title：Journal of forensic sciences
pub_type： 杂志文章
doi：10.1111/1556-4029.13375
更新日期：2017-07-01 00:00:00
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journal_title：Journal of forensic sciences
pub_type： 杂志文章
doi：10.1111/j.1556-4029.2010.01537.x
更新日期：2011-01-01 00:00:00
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journal_title：Journal of forensic sciences
pub_type： 杂志文章
doi：10.1111/j.1556-4029.2007.00655.x
更新日期：2008-03-01 00:00:00
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journal_title：Journal of forensic sciences
pub_type： 杂志文章
doi：10.1111/1556-4029.12069
更新日期：2013-03-01 00:00:00
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journal_title：Journal of forensic sciences
pub_type： 杂志文章
doi：
更新日期：1988-01-01 00:00:00
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journal_title：Journal of forensic sciences
pub_type： 历史文章,杂志文章
doi：10.1111/j.1556-4029.2007.00506.x
更新日期：2007-09-01 00:00:00
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journal_title：Journal of forensic sciences
pub_type： 杂志文章
doi：
更新日期：2005-11-01 00:00:00
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journal_title：Journal of forensic sciences
pub_type： 杂志文章
doi：10.1111/1556-4029.14614
更新日期：2020-11-02 00:00:00
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journal_title：Journal of forensic sciences
pub_type： 杂志文章
doi：
更新日期：1997-09-01 00:00:00
abstract：:Diabetes mellitus (DM) is a common disease involving insulin resistance or deficit that, when left unchecked, may cause severe hyperglycemia and subsequent end-organ damage. Acute pancreatitis (AP) is inflammation of the pancreas that can lead to significant morbidity and mortality. AP and DM both account for a signif...
journal_title：Journal of forensic sciences
pub_type： 杂志文章,评审
doi：10.1111/1556-4029.13268
更新日期：2017-03-01 00:00:00
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journal_title：Journal of forensic sciences
pub_type： 杂志文章
doi：10.1111/j.1556-4029.2010.01688.x
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journal_title：Journal of forensic sciences
pub_type： 杂志文章
doi：
更新日期：1979-04-01 00:00:00
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journal_title：Journal of forensic sciences
pub_type： 杂志文章
doi：
更新日期：1999-05-01 00:00:00
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pub_type： 杂志文章
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journal_title：Journal of forensic sciences
pub_type： 杂志文章
doi：
更新日期：2001-01-01 00:00:00
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journal_title：Journal of forensic sciences
pub_type： 杂志文章
doi：10.1111/1556-4029.12502
更新日期：2014-07-01 00:00:00
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journal_title：Journal of forensic sciences
pub_type： 杂志文章
doi：10.1111/1556-4029.14307
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journal_title：Journal of forensic sciences
pub_type： 杂志文章
doi：10.1111/1556-4029.12841
更新日期：2015-11-01 00:00:00
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journal_title：Journal of forensic sciences
pub_type： 杂志文章
doi：
更新日期：1987-07-01 00:00:00
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journal_title：Journal of forensic sciences
pub_type： 杂志文章
doi：
更新日期：2005-11-01 00:00:00
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journal_title：Journal of forensic sciences
pub_type： 杂志文章
doi：
更新日期：1998-01-01 00:00:00
