Abstract:
BACKGROUND:The benefit of resection of gastric cancer with locoregional invasion is still under debate. This study aimed to investigate the impact of surgery on patients with gastric cancer with locoregional invasion. METHODS:From January 1988 to December 2009, a total of 2,678 patients with gastric cancer underwent surgery at the Department of Surgery, Taipei Veterans General Hospital. Among these patients, 569 and 295 were diagnosed as T4a (serosa invasion without penetration of visceral peritoneum) and T4b (serosa exposure with invasion of adjacent structure), respectively. Invasion type and prognosis were analyzed in patients with gastric cancer who had either curative or palliative resection. RESULTS:Our results showed that patients with T4a gastric cancer had a better 5-year overall survival than patients with T4b (22.5% vs. 11.5%, P < 0.001). Patients with T4b who had curative resection had a better 5-year overall survival than those with T4b who had palliative resection (13.8% vs. 7.3%, P = 0.001). The prognosis of patients with gastric cancer with pancreas invasion was worse than those with mesocolon invasion, as no patients with pancreas invasion survived more than 5 years. Univariate and multivariate analyses showed that tumor size (P = 0.019), Bormann classification (P < 0.001), stromal reaction (P = 0.001), and nodal involvement (P < 0.001) were independent predictors for overall survival in patients with T4b gastric cancer. CONCLUSION:Resection of T4b gastric cancer could be performed with curative intent. Patients with gastric cancer with pancreas invasion had a poorer prognosis than those with mesocolon invasion.
journal_name
World J Surgjournal_title
World journal of surgeryauthors
Lai KK,Fang WL,Wu CW,Huang KH,Chen JH,Lo SS,Li AFdoi
10.1007/s00268-011-1246-9subject
Has Abstractpub_date
2011-11-01 00:00:00pages
2479-84issue
11eissn
0364-2313issn
1432-2323journal_volume
35pub_type
杂志文章abstract:BACKGROUND:Midgut malrotation most commonly presents in young children. This diagnosis is not often entertained in the adolescent or adult with abdominal complaints. We reviewed our experience with this subset of malrotation patients. METHODS:A retrospective review of medical records from adolescent or adult patients ...
journal_title:World journal of surgery
pub_type: 杂志文章
doi:10.1007/s00268-008-9490-3
更新日期:2008-07-01 00:00:00
abstract:PURPOSE:Restorative surgery for rectal cancer is usually criticized by its functional outcomes. The aim of this study is to assess the efficacy "taeniectomy" pouch in comparison with transverse coloplasty pouch. STUDY DESIGN:This was a prospective controlled study. Most patients who were candidate for low rectal resec...
journal_title:World journal of surgery
pub_type: 杂志文章
doi:10.1007/s00268-018-04890-z
更新日期:2019-04-01 00:00:00
abstract:BACKGROUND:Among burn patients, research is conflicted, but may suggest that females are at increased risk of mortality, despite the opposite being true in non-burn trauma. Our objective was to determine whether sex-based differences in burn mortality exist, and assess whether patient demographics, comorbid conditions,...
journal_title:World journal of surgery
pub_type: 杂志文章
doi:10.1007/s00268-019-05165-x
更新日期:2019-12-01 00:00:00
abstract::Congenital short colon (CSC) is a condition in which the colon is replaced, wholly or partially, by a dilated pouch together with anorectal malformation and a colourinary fistula. Most of the reported series have been from northern India where this malformation is frequent. This paper details the management of 108 pat...
journal_title:World journal of surgery
pub_type: 临床试验,杂志文章
doi:10.1007/s002689900019
更新日期:1996-01-01 00:00:00
abstract:INTRODUCTION:The decision to perform a relaparotomy in patients with secondary peritonitis is based on "clinical judgment" with inherent variability among surgeons. Our objective was to review the literature on prognostic variables for ongoing abdominal infection. Predictive variables for positive findings at relaparot...
journal_title:World journal of surgery
pub_type: 杂志文章,评审
doi:10.1007/s00268-005-0333-1
更新日期:2006-12-01 00:00:00
abstract::Intraabdominal hypertension (IAH) and abdominal compartment syndrome (ACS) have detrimental effects on all organ systems and are associated with significant morbidity and mortality. In recent years, the diagnosis and management of these syndromes has evolved tremendously, and the importance of comprehensive strategies...
journal_title:World journal of surgery
pub_type: 杂志文章
doi:10.1007/s00268-009-0003-9
更新日期:2009-06-01 00:00:00
abstract:BACKGROUND:Hepatic resection for hepatocellular carcinoma (HCC) patients with liver cirrhosis and severe hypersplenic thrombocytopenia is risky and controversial. METHODS:From 1989 to 2005, 341 patients underwent hepatic resection for HCC in our hospital. Of these, 15 patients were concomitant with severe thrombocytop...
journal_title:World journal of surgery
pub_type: 杂志文章
doi:10.1007/s00268-007-9442-3
更新日期:2008-06-01 00:00:00
abstract::Surgical exposure of the recurrent laryngeal nerve decreases the incidence of nerve injuries during thyroid surgery. Intraoperative neuromonitoring was introduced to facilitate identification and protection of the recurrent laryngeal nerve. Between February 1996 and June 2002 a total of 288 patients underwent thyroid ...
journal_title:World journal of surgery
pub_type: 杂志文章
doi:10.1007/s00268-004-7226-6
更新日期:2004-06-01 00:00:00
abstract:BACKGROUND:Traditional chemotherapy agents adversely affect wound healing and need to be held prior to or after surgery. Immune checkpoint inhibitors (ICIs) and targeted agents are now standard of care for the several treatment cancers. We hypothesize that ICI and targeted therapy do not have similar adverse effects on...
journal_title:World journal of surgery
pub_type: 杂志文章,评审
doi:10.1007/s00268-019-05314-2
更新日期:2020-04-01 00:00:00
abstract::The present article summarizes scientific observations of the endocrine pancreas anatomy and physiology into a unifying hypothesis. The data were generated over the years by surgical fellows using human and rat isolated perfused pancreas models and in vivo islet microcirculation models. The endocrine pancreas secretes...
journal_title:World journal of surgery
pub_type: 杂志文章,评审
doi:10.1007/s002680020339
更新日期:2001-04-01 00:00:00
abstract:OBJECTIVE:The prognosis of Fournier's gangrene (FG) depends on early diagnosis and management. In this study, our objective was to identify the distinct features of FG that may influence the clinical outcome. METHODS:A retrospective chart review was performed in patients with a diagnosis of FG between January 1999 and...
journal_title:World journal of surgery
pub_type: 杂志文章
doi:10.1007/s00268-005-0777-3
更新日期:2006-09-01 00:00:00
abstract:BACKGROUND:Enhanced recovery (ERAS) guidelines do not differentiate between left- and right-sided colectomies, but differences in recovery have been reported for the two procedure types. We aimed to compare compliance with the ERAS protocol and outcomes after right versus left colectomy. METHODS:Between June 2011 and ...
journal_title:World journal of surgery
pub_type: 杂志文章
doi:10.1007/s00268-016-3563-5
更新日期:2016-10-01 00:00:00
abstract::The surgical treatment of 30 cases of vascular thoracic outlet syndrome (TOS) in 25 patients is presented. Patients included 17 women and 8 men with average age of 26.1 years. The causes of compression were cervical rib ( n = 16), soft tissue anomalies ( n = 12), and scar tissue after clavicle fracture ( n = 2). Ten s...
journal_title:World journal of surgery
pub_type: 杂志文章
doi:10.1007/s00268-003-6808-z
更新日期:2003-05-01 00:00:00
abstract:BACKGROUND:Emerging evidences have gradually revealed the skeletal muscle attenuation (MA) was not only reflected the accumulation of lipids in skeletal muscle but also associated with physiological and pathological states. The aim of this study was to evaluate the impact of MA on the prognosis of pancreatic cancer pat...
journal_title:World journal of surgery
pub_type: 杂志文章
doi:10.1007/s00268-015-3205-3
更新日期:2015-12-01 00:00:00
abstract:BACKGROUND:Accurate, complete and sustainable methods of tracking patients and outcomes in low-resource settings are imperative as we launch efforts to improve surgical care globally. The Surgical services QUality Assessment Database (SQUAD) at the Mbarara Regional Referral Hospital in Uganda is one of very few electro...
journal_title:World journal of surgery
pub_type: 杂志文章
doi:10.1007/s00268-017-4172-7
更新日期:2018-01-01 00:00:00
abstract::From January, 1972 to June, 1989, 51 patients with liver hemangiomas (32 females and 19 males, mean age 35 years) were evaluated for surgical treatment. Diameters of the masses were 5 cm to 20 cm (median 8.5 cm). Nine of the patients had already been treated for cancer. Twenty-two (43.1%) of the 51 patients were sympt...
journal_title:World journal of surgery
pub_type: 杂志文章
doi:10.1007/BF02104457
更新日期:1992-05-01 00:00:00
abstract:BACKGROUND:Postoperative ascites (POA) is a common complication after liver resection (LR). The aim of the present study was to identify the risk factors for developing POA and to evaluate its clinical significance in the prognosis of patients with hepatocellular carcinoma (HCC). METHODS:We performed a retrospective a...
journal_title:World journal of surgery
pub_type: 杂志文章
doi:10.1007/s00268-011-1367-1
更新日期:2012-02-01 00:00:00
abstract:BACKGROUND:Only few studies have compared laparoscopic total mesorectal excision (LTME) and open total mesorectal excision (OTME) for rectal cancer with follow-up longer than 5 years. The aim of this study was to compare 10-year oncologic outcomes after LTME and OTME for nonmetastatic rectal cancer. METHODS:We conduct...
journal_title:World journal of surgery
pub_type: 杂志文章
doi:10.1007/s00268-016-3631-x
更新日期:2016-12-01 00:00:00
abstract:PURPOSE:Recurrent laryngeal nerve (RLN) palsy is the major concern of reoperative thyroid surgery, and the introduction of neuromonitoring could reduce the rate of this complication. The present study is a retrospective analysis of the experience with completion thyroidectomy with and without neuromonitoring in a refer...
journal_title:World journal of surgery
pub_type: 杂志文章
doi:10.1007/s00268-012-1548-6
更新日期:2012-06-01 00:00:00
abstract::Cost-benefit and cost-effectiveness analyses (CEAs) are only now beginning to be used by business, government, and policymakers to evaluate various medical treatments. The evolution of why CEAs are being demanded is reviewed. To date, a formal CEA of obesity treatments has not been published. This article outlines how...
journal_title:World journal of surgery
pub_type: 杂志文章
doi:10.1007/s002689900508
更新日期:1998-09-01 00:00:00
abstract::Recently, surgical services have been gaining greater attention as an integral part of public health in low-income countries due to the significant volume and burden of surgical conditions, growing evidence of the cost-effectiveness of surgical intervention, and global disparities in surgical care. Nonetheless, there ...
journal_title:World journal of surgery
pub_type: 杂志文章
doi:10.1007/s00268-010-0585-2
更新日期:2010-11-01 00:00:00
abstract:BACKGROUND:The retained knife blade is an unusual and spectacular injury. The aim of this study was to review our experience with the management of such injuries. METHODS:A retrospective chart review of patients with retained knife blades treated at Groote Schuur Hospital Trauma Centre from January 1996 to December 20...
journal_title:World journal of surgery
pub_type: 杂志文章
doi:10.1007/s00268-010-0514-4
更新日期:2010-07-01 00:00:00
abstract:BACKGROUND:We assessed whether the simultaneous sequential strategy could (1) achieve additional sinus restoration for those patients who were not in sinus rhythm while coming off bypass after modified left maze procedure and (2) attain the same long-term success rates as the bi-atrial maze procedure in patients with p...
journal_title:World journal of surgery
pub_type: 杂志文章
doi:10.1007/s00268-006-0382-0
更新日期:2006-10-01 00:00:00
abstract::A minority of patients with papillary thyroid carcinoma (PTC) is at high-risk of developing recurrent disease and death. Risk group stratification as defined by age, metastases to distant site, extrathyroidal invasion, and tumor size (AMES) criteria is frequently employed to identify high-risk patients for aggressive ...
journal_title:World journal of surgery
pub_type: 杂志文章
doi:10.1007/s00268-004-7420-6
更新日期:2004-11-01 00:00:00
abstract:BACKGROUND:The aim of this study was to determine the predictive value of the preoperative three-dimensional reconstructed volume (3D volumetry) for outcomes of laparoscopic splenectomy. The impact of splenomegaly on the feasibility of laparoscopic splenectomy is still debated. We hypothesized that splenic volumetry ma...
journal_title:World journal of surgery
pub_type: 杂志文章
doi:10.1007/s00268-012-1789-4
更新日期:2013-01-01 00:00:00
abstract:BACKGROUND:Complications are important indicators of immediate postoperative outcomes. The Clavien-Dindo classification (CDC) is a widely used index for the classification of surgical complications. More recently, the comprehensive complication index (CCI) has also been introduced for classifying postoperative complica...
journal_title:World journal of surgery
pub_type: 杂志文章
doi:10.1007/s00268-020-05859-7
更新日期:2021-03-01 00:00:00
abstract:INTRODUCTION:The past 25 years have been witness to a revolution in how vascular care is delivered. The majority of arterial and venous interventions have converted from open surgery to minimally invasive percutaneous endovascular procedures. METHODS:This surgical innovations symposium article reviews current endovasc...
journal_title:World journal of surgery
pub_type: 杂志文章
doi:10.1007/s00268-020-05875-7
更新日期:2020-11-22 00:00:00
abstract:BACKGROUND:Postoperative peritonitis (POP) following gastrointestinal surgery is associated with significant morbidity and mortality, with no clear management option proposed. The aim of this study was to report our surgical management of POP and identify pre- and perioperative risk factors for morbidity and mortality....
journal_title:World journal of surgery
pub_type: 杂志文章
doi:10.1007/s00268-018-4687-6
更新日期:2018-11-01 00:00:00
abstract::The metabolic changes in cancer cachexia appear to be mediated by a complex network of proinflammatory cytokines, neuroendocrine hormones, neurotransmitters, eicosanoids, and tumor-derived factors produced by the body in response to the tumor and by the tumor itself. The relative importance of these various mediator p...
journal_title:World journal of surgery
pub_type: 杂志文章,评审
doi:10.1007/s002689910110
更新日期:2000-06-01 00:00:00
abstract:BACKGROUND:There are many reports about limited surgery for intraductal papillary mucinous neoplasms (IPMNs) of the pancreas. However, there is no consensus on limited surgery for IPMNs. The primary objective of this study was to define the clinical indications for limited surgery for IPMNs. METHODS:The data of 98 pat...
journal_title:World journal of surgery
pub_type: 杂志文章
doi:10.1007/s00268-016-3824-3
更新日期:2017-05-01 00:00:00