Abstract:
STUDY DESIGN:Prospective, randomized, controlled, multicenter clinical trial. OBJECTIVE:To compare outcomes of cervical disc arthroplasty with those of anterior cervical decompression and fusion (ACDF) in a Chinese population. SUMMARY OF BACKGROUND DATA:Cervical disc arthroplasty has been found to be superior to ACDF for maintaining range of motion (ROM) at the index spinal segment and possibly will avoid abnormal stress to adjacent segments. METHODS:A total of 120 patients from 3 large hospitals in China were randomly assigned to treatment with cervical disc arthroplasty (n = 60) using the BRYAN prosthesis or ACDF (n = 60) and were observed postoperatively for 24 months. RESULTS:The 2 groups had similar preoperative demographics and baseline characteristics including ROM, neck disability index, and visual analogue scale for neck and arm pain. The total disc replacement (TDR) group had a significantly longer operation time than the ACDF group (P < 0.001). Outcome data obtained after 24 months revealed a significant difference between the groups in mean change from baseline in ROM at the index level (P < 0.001); ROM was maintained in the TDR group but reduced in the ACDF group. There were no significant between-group differences in the baseline changes in neck disability index or visual analogue scale scores for pain. One patient in the TDR group and 4 patients in the ACDF group required reoperations. CONCLUSION:At 24 months after surgery, the cervical disc prosthesis yielded good clinical results while maintaining ROM at the index level. Cervical disc arthroplasty appears to be a viable alternative to ACDF.
journal_name
Spine (Phila Pa 1976)journal_title
Spineauthors
Zhang X,Zhang X,Chen C,Zhang Y,Wang Z,Wang B,Yan W,Li M,Yuan W,Wang Ydoi
10.1097/BRS.0b013e31822699fasubject
Has Abstractpub_date
2012-03-15 00:00:00pages
433-8issue
6eissn
0362-2436issn
1528-1159journal_volume
37pub_type
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