Abstract:
STUDY DESIGN:Retrospective. OBJECTIVE:With approximately 10,000 new spinal cord injury (SCI) patients in the United States each year, predicting public health outcomes is an important public health concern. Combining all regions of the spine in SCI trials may be misleading if the lumbar and sacral regions (conus) have a neurologic improvement at different rates than the thoracic or thoracolumbar spinal cord. SUMMARY OF BACKGROUND DATA:Over a 10-year period between January 1995 to 2005, 1746 consecutive spinal injured patients were seen, evaluated, and treated through a level 1 trauma referral center. A retrospective analysis was performed on 150 patients meeting the criteria of T4 to S5 injury, excluding gunshot wounds. One-year follow-up data were available on 95 of these patients. METHODS:Contingency table analyses (chi-squared statistics) and multivariate logistic regression. Variables of interest included level of injury, initial American Spinal Injury Association (ASIA), age, race, and etiology. RESULTS:A total of 92.9% of lumbar (conus) patients neurologically improved one ASIA level or more compared with 22.4% of thoracic or thoracolumbar spinal cord-injured patients. Only 7.7% of ASIA A patients showed neurologic improvement, compared with 95.2% of ASIA D patients; ASIA B patients demonstrated a 66.7% improvement rate, whereas ASIA C had a 84.6% improvement rate. When the two effects were considered jointly in a multivariate analysis, ASIA A and thoracic/thoracolumbar patients had only a 4.1% rate of improvement, compared with 96% for lumbar (conus) and incomplete patients (ASIA B-D) and 66.7% to 72.2% for the rest of the patients. All of these relationships were significant to P < 0.001 (chi-square test). There was no link to age or gender, and race and etiology were secondary to region and severity of injury. CONCLUSION:Thoracic (T4-T9) SCIs have the least potential for neurologic improvement. Thoracolumbar (T10-T12) and lumbar (conus) spinal cord have a greater neurologic improvement rate, which might be related to a greater proportion of lower motor neurons. Thus, defining the exact region of injury and potential for neurologic improvement should be considered in future clinical trial design. Combining all anatomic regions of the spine in SCI trials may be misleading if different regions have neurologic improvement at different rates. Over a ten-year period, 95 complete thoracic/thoracolumbar SCI patients had only a 4.1% rate of neurologic improvement, compared with 96.0% for incomplete lumbar (conus) patients and 66.7% to 72.2% for all others.
journal_name
Spine (Phila Pa 1976)journal_title
Spineauthors
Harrop JS,Naroji S,Maltenfort MG,Ratliff JK,Tjoumakaris SI,Frank B,Anderson DG,Albert T,Vaccaro ARdoi
10.1097/BRS.0b013e3181fd6b36subject
Has Abstractpub_date
2011-01-01 00:00:00pages
21-5issue
1eissn
0362-2436issn
1528-1159pii
00007632-201101010-00005journal_volume
36pub_type
杂志文章相关文献
SPINE文献大全abstract:STUDY DESIGN:Posture and motion analysis after a Cotrel-Dubousset instrumentation. OBJECTIVES:To investigate the compensation role of pelvis. SUMMARY OF BACKGROUND DATA:Few existing studies found no compensation at the lower unfused level but did not investigate the pelvis. METHODS:Thirty patients were analyzed befo...
journal_title:Spine
pub_type: 杂志文章
doi:10.1097/01.brs.0000219402.01636.87
更新日期:2006-05-20 00:00:00
abstract:STUDY DESIGN:Agreement study. OBJECTIVE:To perform an independent interobserver and intraobserver agreement evaluation of the new AOSpine Thoracolumbar Spine Injury Classification System. SUMMARY OF BACKGROUND DATA:The new AOSpine Thoracolumbar Spine Injury Classification System was recently published. It showed subs...
journal_title:Spine
pub_type: 杂志文章
doi:10.1097/BRS.0000000000000656
更新日期:2015-01-01 00:00:00
abstract::Improving spinal fusion by optimizing scaffold and surface engineering is a topic of interest for both surgeons and researchers. Concerns regarding patient safety with off-label use of bone morphogenetic protein (BMP) have increased, and patients are choosing minimally invasive spine surgery to lessen morbidity by avo...
journal_title:Spine
pub_type: 杂志文章
doi:10.1097/BRS.0000000000001426
更新日期:2016-04-01 00:00:00
abstract:STUDY DESIGN:Randomized prevention trial. OBJECTIVE:To compare the long-term effect of strengthening versus flexibility exercises and to evaluate the additional effect of abdominal bracing in recurrent low back pain (LBP). SUMMARY OF BACKGROUND DATA:No conclusions could be made regarding appropriate exercise types or...
journal_title:Spine
pub_type: 杂志文章,随机对照试验
doi:10.1097/BRS.0000000000000338
更新日期:2014-06-01 00:00:00
abstract:STUDY DESIGN:Retrospective clinical series. OBJECTIVE:To compare perioperative parameters, clinical outcomes, radiographic parameters, and complication rates of three reconstructive techniques after the anterior decompression of four-level cervical spondylotic myelopathy (CSM). SUMMARY OF BACKGROUND DATA:At present, ...
journal_title:Spine
pub_type: 杂志文章
doi:10.1097/BRS.0000000000001907
更新日期:2017-05-15 00:00:00
abstract:STUDY DESIGN:A case report and literature review of the five previous case reports. OBJECTIVES:To outline the features of Torulopsis glabrata spinal osteomyelitis, including its risk factors, diagnosis, and recommended treatments. SUMMARY OF BACKGROUND DATA:Fungal infections in general and Torulopsis glabrata in part...
journal_title:Spine
pub_type: 杂志文章,评审
doi:10.1097/00007632-199604010-00019
更新日期:1996-04-01 00:00:00
abstract:STUDY DESIGN:Retrospective review comparing physician workup of degenerative lumbosacral pathologies between different genders and ethnic groups. OBJECTIVES:To investigate whether patient ethnicity and gender influence the workup and treatment of degenerative spinal pathologies. SUMMARY OF BACKGROUND DATA:Data from n...
journal_title:Spine
pub_type: 杂志文章,多中心研究
doi:10.1097/01.brs.0000152115.79236.6e
更新日期:2005-02-01 00:00:00
abstract::The relationship betewwn compensation and three variables--psychologic disturbance, organic status, and pain report characteristics--was assessed. Patients on compensation were clinically similar to patients not on compensation in the relative frequency of cases of psychologic disturbance and nonorganic findings in ea...
journal_title:Spine
pub_type: 杂志文章
doi:10.1097/00007632-198207000-00010
更新日期:1982-07-01 00:00:00
abstract:STUDY DESIGN:Literature-based topic review. OBJECTIVE:To review the indications and techniques for different sacropelvic fixation methods and to outline important associated complications. SUMMARY OF BACKGROUND DATA:Despite all the advances and new developments in spinal instrumentation techniques, fixation at the lu...
journal_title:Spine
pub_type: 杂志文章,评审
doi:10.1097/BRS.0b013e3181f5cfae
更新日期:2010-12-01 00:00:00
abstract:STUDY DESIGN:A retrospective review was conducted covering records of patients who underwent spinal surgery after acute spinal cord injury. OBJECTIVE:To study the relation between time of operation and mobilization of patients. SUMMARY OF BACKGROUND DATA:No such report has existed in the literature. METHODS:Reviews ...
journal_title:Spine
pub_type: 杂志文章
doi:10.1097/00007632-200110150-00022
更新日期:2001-10-15 00:00:00
abstract:STUDY DESIGN:In vitro biomechanical study to evaluate the stability of different types of instrumentation in the lumbar spine following corpectomy in relation to bone mineral density (BMD). OBJECTIVES:To investigate the relation between the stability of a spinal instrumentation and BMD. To determine a threshold value ...
journal_title:Spine
pub_type: 杂志文章
doi:10.1097/01.brs.0000161000.36376.c5
更新日期:2005-05-01 00:00:00
abstract:STUDY DESIGN:Case series and review of literature. OBJECTIVE:To report three cases of vascular injury during posterior lumbar disc surgery, two of these occurred during open discectomy, and one during an endoscopic surgery. Aim is to highlight importance of early diagnosis and prompt steps taken to prevent morbidity a...
journal_title:Spine
pub_type: 杂志文章,评审
doi:10.1097/BRS.0000000000003100
更新日期:2019-10-15 00:00:00
abstract:STUDY DESIGN:Retrospective case series study of surgical outcome for 21 atlantoaxial subluxation patients treated with a new technique, called cable-dragged reduction/cantilever beam internal fixation. Surgery was performed by a single surgeon. OBJECTIVE:To describe and evaluate the cable-dragged reduction/cantilever ...
journal_title:Spine
pub_type: 杂志文章
doi:10.1097/BRS.0b013e3181feb6b1
更新日期:2011-07-01 00:00:00
abstract:STUDY DESIGN:System validation study. OBJECTIVE:To develop and validate a motion sensor system for measuring cervical spine motion over extended time periods. SUMMARY OF BACKGROUND DATA:Many studies using different methodologies have tried to estimate cervical spine motion. These have mostly been carried out in a lab...
journal_title:Spine
pub_type: 杂志文章
doi:10.1097/BRS.0b013e318145a93a
更新日期:2007-09-01 00:00:00
abstract::To study possible neurologic complications, five lambs were operated on by sublaminar wiring at the thoracolumbar spine. Monitoring of the central motor pathway was carried out by percutaneous electrostimulation. A comparative anatomic study was designed to compare the magnitude of the spinal canal and the area occupi...
journal_title:Spine
pub_type: 杂志文章
doi:10.1097/00007632-199204000-00011
更新日期:1992-04-01 00:00:00
abstract::Electromyographic studies have determined that muscle imbalance and asymmetry of stretch receptors in the paraspinal muscle of patients with idiopathic scoliosis may have a large role to play in the development and production of the deformity. This project consisted of a detailed histologic and histochemical analysis ...
journal_title:Spine
pub_type: 杂志文章
doi:10.1097/00007632-198805000-00004
更新日期:1988-05-01 00:00:00
abstract::The authors attempted to investigate the effect of vibration on the physiologic behavior of the intervertebral disc from rheologic and biological responses. Using fresh disc-cartilaginous end plate complexes of porcine coccygeal vertebrae, the frequency characteristics of dynamic compressive elastic modulus and dissip...
journal_title:Spine
pub_type: 杂志文章
doi:10.1097/00007632-199203001-00002
更新日期:1992-03-01 00:00:00
abstract::Harrington rod treatment for spinal trauma has become the gold standard against which other treatment modalities are judged. A review of the results of Harrington rod treatment is essential to establish a baseline level of efficiency in terms of rehabilitation time, correction of deformity, canal decompression, motion...
journal_title:Spine
pub_type: 杂志文章,评审
doi:
更新日期:1993-03-15 00:00:00
abstract:STUDY DESIGN:A retrospective multicenter study. OBJECTIVE:To investigate the relationship between the lowest instrumented, stable, and lower end vertebrae in patients with "single overhang" thoracic (main thoracic) curves treated with anterior or posterior spinal fusion. SUMMARY OF BACKGROUND DATA:Previous studies ha...
journal_title:Spine
pub_type: 杂志文章,多中心研究
doi:10.1097/01.brs.0000232799.19179.79
更新日期:2006-09-01 00:00:00
abstract:STUDY DESIGN:Retrospective cohort study. OBJECTIVE:To identify factors associated with blood transfusion for primary posterior lumbar fusion surgery, and to identify associations between blood transfusion and other postoperative complications. SUMMARY OF BACKGROUND DATA:Blood transfusion is a relatively common occurr...
journal_title:Spine
pub_type: 杂志文章
doi:10.1097/BRS.0000000000001047
更新日期:2015-11-01 00:00:00
abstract:STUDY DESIGN:Retrospective literature review. OBJECTIVE:To assess the quality of randomized controlled trial reporting in spine surgery. SUMMARY OF BACKGROUND DATA:The use of the Consolidated Standards of Reporting Trials (CONSORT) criteria in clinical trials aims to improve adherence to a set of generally accepted p...
journal_title:Spine
pub_type: 杂志文章,评审
doi:10.1097/BRS.0b013e3181f2aef0
更新日期:2011-07-15 00:00:00
abstract:STUDY DESIGN:Feasibility analysis of percutaneous posterolateral thoracic microendoscopic discectomy in a human cadaver model. OBJECTIVE:To describe a new, minimally invasive, posterolateral approach to the thoracic spine for the treatment of disc herniations. SUMMARY OF BACKGROUND:Thoracoscopic discectomy offers sur...
journal_title:Spine
pub_type: 杂志文章
doi:10.1097/01.brs.0000162275.95579.ee
更新日期:2005-05-15 00:00:00
abstract:STUDY DESIGN:Systematic review. OBJECTIVE:To investigate the effects of Kinesio Taping (KT) in patients with nonspecific low back pain. SUMMARY OF BACKGROUND DATA:KT is widely used in patients with low back pain. METHODS:We conducted searches on PubMed, EMBASE, PEDro, SciELO, and LILACS up to February 26, 2018. We i...
journal_title:Spine
pub_type: 杂志文章,meta分析
doi:10.1097/BRS.0000000000002756
更新日期:2019-01-01 00:00:00
abstract:STUDY DESIGN:The distribution of the lumbar plexus was analyzed using cadavers. OBJECTIVE:To clarify the safety zone to prevent nerve injuries with respect to retroperitoneal endoscopic surgery. SUMMARY OF BACKGROUND DATA:Surgical approaches to the retroperitoneal space vary among surgeons. Recently, retroperitoneal ...
journal_title:Spine
pub_type: 杂志文章
doi:10.1097/01.BRS.0000049226.87064.3B
更新日期:2003-03-01 00:00:00
abstract:STUDY DESIGN:Retrospective cohort analysis of prospectively collected clinical data. OBJECTIVE:To compare outcomes of elective spine fusion and laminectomy when performed by neurological and orthopedic surgeons. SUMMARY OF BACKGROUND DATA:The relationship between primary specialty training and outcome of spinal surge...
journal_title:Spine
pub_type: 杂志文章
doi:10.1097/BRS.0000000000000489
更新日期:2014-09-01 00:00:00
abstract::Techniques for assessing daily function in Patients with back pain are generally crude and limited in scope. We therefore examined a "health status" questionnaire, the Sickness Impact Profile (SIP) to assess its measurement characteristics in such patients. Eighty patients with mechanical low-back pain completed the S...
journal_title:Spine
pub_type: 杂志文章
doi:10.1097/00007632-198309000-00009
更新日期:1983-09-01 00:00:00
abstract:STUDY DESIGN:The possible role of phospholipase A2 in an animal model for lumbar radiculopathy and mechanisms of epidural steroid injections were studied. OBJECTIVES:To clarify the pathophysiologic mechanism of the recently proved animal model for lumbar radiculopathy and to characterize further the mechanisms of acti...
journal_title:Spine
pub_type: 杂志文章
doi:10.1097/00007632-199806010-00001
更新日期:1998-06-01 00:00:00
abstract:STUDY DESIGN:The histology of lumbar intertransverse process spinal fusion was studied in an experimental model in rabbits. OBJECTIVES:To qualitatively and quantitatively analyze the sequential histology of spinal fusion using a previously validated animal model. SUMMARY OF BACKGROUND DATA:Few previous studies have d...
journal_title:Spine
pub_type: 杂志文章
doi:10.1097/00007632-199512150-00003
更新日期:1995-12-15 00:00:00
abstract:STUDY DESIGN:The strength of posterior cervical lateral mass fixation was evaluated in a cadaver model for two techniques of screw insertion. OBJECTIVE:To compare the flexion failure strengths of posterior cervical plate fixation for two techniques of screw placement at the superior and inferior screw hole positions, ...
journal_title:Spine
pub_type: 杂志文章
doi:10.1097/00007632-199602150-00010
更新日期:1996-02-15 00:00:00
abstract:STUDY DESIGN:A numerical study was conducted by simulating in situ contouring (ISC) surgery. OBJECTIVE:To quantify intraoperative correction during ISC surgery. SUMMARY OF BACKGROUND DATA:Surgical techniques correcting scoliosis, like the ISC one, lead to a complex 3-dimensional correction of the spine. Using motion ...
journal_title:Spine
pub_type: 杂志文章
doi:10.1097/BRS.0b013e3181b8eaca
更新日期:2010-02-15 00:00:00