Controversies in pathology in early-stage breast cancer.

Abstract:

:Breast-conserving therapy is a reliable, evidenced-based approach for early-stage breast carcinoma. This article reviews the issues and limitations related to simple margin measurements, data supporting the association between the amount of carcinoma near the margin, and ipsilateral breast failure risk. Additional factors pertinent to radiation oncologists include extensive intraductal carcinoma, lymphovascular space invasion, atypical ductal hyperplasia, and molecular clonality of ipsilateral breast failures as they relate to outcome.

journal_name

Semin Radiat Oncol

authors

Goldstein SN

doi

10.1016/j.semradonc.2010.08.003

subject

Has Abstract

pub_date

2011-01-01 00:00:00

pages

20-5

issue

1

eissn

1053-4296

issn

1532-9461

pii

S1053-4296(10)00062-7

journal_volume

21

pub_type

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