Use of HbA(1c) in screening for Cuban-Americans with undiagnosed type 2 diabetes.

Abstract:

:This study evaluated the use of HbA(1c) as a screening tool for undiagnosed type 2 diabetes (fasting plasma glucose ≥7.0 mmol/l) in a sample of Cuban-Americans aged ≥ 30 years old. Subjects were randomly recruited from Miami-Dade and Broward counties, FL. Fasting plasma glucose was measured by hexokinase enzymatic method. HbA(1c) was measured by the DCA2000 + system using the monoclonal antibody method. HbA(1c) demonstrated a high predictive value in detecting undiagnosed diabetes. The area under the receiver operating characteristics (ROC) curve was 0.87. Also, HbA(1c) had high sensitivity and specificity when using a cut off value of 6.37 (71 and 86%, respectively). Moderate sensitivity and very high specificity were shown with a cut off value of 6.84 (57 and 96%, respectively). HbA(1c) is a reliable alternative to fasting plasma glucose in screening for undiagnosed diabetes in Cuban-Americans.

journal_name

J Immigr Minor Health

authors

Huffman FG,Exebio JC,Zarini GG,Exebio C

doi

10.1007/s10903-010-9363-3

subject

Has Abstract

pub_date

2011-06-01 00:00:00

pages

541-5

issue

3

eissn

1557-1912

issn

1557-1920

journal_volume

13

pub_type

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