Abstract:
:We report a case of a 43-year-old woman, affected by human immunodeficiency virus (HIV) and beta-thalassemia major (beta-TM), adequately treated with antiretroviral and transfusion-chelation therapy, that develops progressive right ventricular dysfunction due to severe pulmonary arterial hypertension (PAH), in absence of symptoms. The existence of both HIV and beta-TM cardiomiopathy has recently been reported, but how these two diseases have a "competition of guilt" for creating PAH is still to be understood. The main physiopathological principles regarding HIV and beta-TM associated PAH are reviewed. The possible interplay between these two different pathologies is discussed.
journal_name
Hemoglobinjournal_title
Hemoglobinauthors
Derchi G,Lai ME,Marcaccini P,Carta MP,Vacquer Sdoi
10.3109/03630260903547765subject
Has Abstractpub_date
2010-01-01 00:00:00pages
61-6issue
1eissn
0363-0269issn
1532-432Xjournal_volume
34pub_type
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