Abstract:
:Recent studies concerning molecular mechanisms of genetic recombination in eukaryotes are reviewed. Since many of these studies have focused on the testable predictions arising from the hybrid DNA theory of genetic recombination, this theory is summarised. Experiments to determine the time of meiotic crossing-over and the structure of the synaptonemal complex which facilitates meiotic crossing-over are described. Investigations of DNA nicking and repair events implicated in recombination are discussed. Properties of proteins which may facilitate hybrid DNA formation, and biochemical evidence for hybrid DNA formation are presented. Finally, a nuclease which has been implicated in gene conversion is described.
journal_name
Heredity (Edinb)journal_title
Heredityauthors
Pukkila PJdoi
10.1038/hdy.1977.61subject
Has Abstractpub_date
1977-10-01 00:00:00pages
193-217issue
2eissn
0018-067Xissn
1365-2540journal_volume
39pub_type
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