Abstract：
OBJECTIVE:To determine the changes in number and morphology of interstitial cells of Cajal (ICC)-like cells (ICC-LC) at the ureteropelvic junction (UPJ) of rats after experimental distal ureteral obstruction. MATERIALS AND METHODS:Of a total of 109 rats, 20 served as controls (C), 20 underwent sham-operations (SH) and 69 were in the study (S) groups. The UPJs were extracted initially in the C and SH groups, and 7, 14, 30, 60 and 90 days after ligation of the distal ureter in the study groups (S1, S2, S3, S4 and S5, respectively). The sections stained by c-kit anticore were studied under a light microscope. RESULTS:The mean number of ICC-LC was 4.55+/-2.21 in C, 5.15+/-3.51 in SH, 7.40+/-6.88 in S1, 21.16+/-19.03 in S2, 12.63+/-8.16 in S3, 10.40+/-5.09 in S4, and 10.9+/-6.33 in S5. There was a statistically significant increase in ICC-LC in the study groups, except S1, compared to the C and SH groups. No significant difference was detected in Cajal cell morphology and distribution pattern between groups. CONCLUSIONS:Based on the changes in number of ICC-LC at the UPJ after obstruction of the distal ureter compared with the limited data available in the literature, we suggest that ICC-LC have a close relationship with motility of the ureter.
journal_name
J Pediatr Uroljournal_title
Journal of pediatric urologyauthors
Kuzgunbay B,Doran F,Bayazit Y,Turunc T,Satar N,Kayis AAdoi
10.1016/j.jpurol.2008.12.006subject
Has Abstractpub_date
2009-08-01 00:00:00pages
269-73issue
4eissn
1477-5131issn
1873-4898pii
S1477-5131(08)00449-Xjournal_volume
5pub_type
杂志文章abstract：INTRODUCTION:Laparoscopic pyeloplasty has achieved good cosmetic and functional outcomes. Both transumbilical single-site and transumbilical multi-port approaches are currently being used. No comparison of transumbilical single-site laparoscopic pyeloplasty (TSLP) and transumbilical multi-port laparoscopic pyeloplasty ...
journal_title：Journal of pediatric urology
pub_type： 杂志文章
doi：10.1016/j.jpurol.2017.05.009
更新日期：2017-12-01 00:00:00
abstract：OBJECTIVE:Extravesical robot-assisted laparoscopic ureteral reimplantation (RALUR) is a popular alternative to open surgery. We report our experience with RALUR and evaluate clinical variables as predictors for failure. METHODS:We retrospectively evaluated the records of patients who underwent RALUR by a single surgeo...
journal_title：Journal of pediatric urology
pub_type： 杂志文章
doi：10.1016/j.jpurol.2014.01.028
更新日期：2014-10-01 00:00:00
abstract：:Renal medullary carcinoma is a lethal subtype of renal cancer that afflicts patients with sickle-cell hemoglobinopathies. Here we present the case of a 13-year-old boy with renal medullary carcinoma who is the first, to our knowledge, to be managed using a planned laparoscopic radical nephrectomy. ...
journal_title：Journal of pediatric urology
pub_type： 杂志文章
doi：10.1016/j.jpurol.2007.02.007
更新日期：2008-02-01 00:00:00
abstract：BACKGROUND:Acute pyelonephritis is associated with renal scarring in up to 30% of patients. Renal scarring may cause significant long-term morbidity. The pathogenesis of acute pyelonephritis remains unclear, although it involves interaction among uroepithelium, the immune system cells, and the locally produced cytokine...
journal_title：Journal of pediatric urology
pub_type： 杂志文章
doi：10.1016/j.jpurol.2017.05.025
更新日期：2017-12-01 00:00:00
abstract：INTRODUCTION:Non-Wilms renal tumors represent a compelling subset of childhood renal tumors. However, their relative rarity renders accurate diagnosis, and therapy challenging which in some instance is inferred from their adult counterparts. OBJECTIVE:To describe the incidence and analyze the diagnostic challenges, th...
journal_title：Journal of pediatric urology
pub_type： 杂志文章
doi：10.1016/j.jpurol.2020.05.168
更新日期：2020-08-01 00:00:00
abstract：OBJECTIVE:In principle, the prepuce can be reconstructed during hypospadias repair, but the procedure has not gained wide acceptance and preputial reconstruction (PR) is surrounded by several controversies. MATERIAL AND METHODS:A review is provided of the technique for PR, how PR combines with the other steps of hypos...
journal_title：Journal of pediatric urology
pub_type： 杂志文章,评审
doi：10.1016/j.jpurol.2016.07.018
更新日期：2017-02-01 00:00:00
abstract：:We examined the use of shared medical appointments (SMA) for educating and counseling children with penile problems. Forty-eight families were seen over 4 months with 21 participating in the SMA group and 27 in the traditional group. Using a questionnaire to assess adequacy of education, there was no difference in the...
journal_title：Journal of pediatric urology
pub_type： 杂志文章
doi：10.1016/j.jpurol.2017.09.030
更新日期：2018-02-01 00:00:00
abstract：INTRODUCTION:The use of administrative health data for research has prompted questions about its validity for this purpose. OBJECTIVE/STUDY DESIGN:The purpose of this study was to determine the concordance of Pediatric Health Information System (PHIS) perioperative antibiotic charges with the institution's medication ...
journal_title：Journal of pediatric urology
pub_type： 杂志文章
doi：10.1016/j.jpurol.2017.01.009
更新日期：2017-04-01 00:00:00
abstract：BACKGROUND:Although shown to be safe in infancy, robotic-assisted laparoscopic pyeloplasty (RALP) for ureteropelvic junction obstruction (UPJO) is most commonly performed in older children and adolescents. OBJECTIVE:This study examined a contemporary RALP experience at a single tertiary pediatric center and compared o...
journal_title：Journal of pediatric urology
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doi：10.1016/j.jpurol.2018.04.023
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abstract：INTRODUCTION:Robot-assisted laparoscopic pyeloplasty (RALP) has been gaining acceptance among pediatric urologists. Over 300 have been described in the literature, but few studies have evaluated the role of RALP in infants alone. OBJECTIVE:We sought to examine the operative experience and outcomes of RALP in a cohort ...
journal_title：Journal of pediatric urology
pub_type： 杂志文章,多中心研究
doi：10.1016/j.jpurol.2014.11.025
更新日期：2015-06-01 00:00:00
abstract：PURPOSE:To evaluate the outcome of secondary surgical procedures for the management of failed pyeloplasty in children. MATERIALS AND METHODS:Between 1996 and 2007, 590 cases of primary ureteropelvic junction (UPJ) obstruction underwent open dismembered pyeloplasty at our center. Of these patients, 18 (3%) with recurre...
journal_title：Journal of pediatric urology
pub_type： 杂志文章
doi：10.1016/j.jpurol.2008.09.001
更新日期：2009-04-01 00:00:00
abstract：:Uro-enteric fistulae are difficult clinical conditions that have a significant bearing on the patient's quality of life. Surgical correction, though challenging, is the usual mode of treatment offered to these patients. We describe a case of urethro-ileal pouch fistula which could be managed successfully without surge...
journal_title：Journal of pediatric urology
pub_type： 杂志文章
doi：10.1016/j.jpurol.2011.06.007
更新日期：2012-02-01 00:00:00
abstract：OBJECTIVE:To report a novel cause of nocturnal enuresis (NE) and highlight the literature giving insight into this novel mechanism. PATIENT:A 12-year-old morbidly obese female with 2-year history of nightly secondary monosymptomatic NE. RESULTS:On evaluation, a history of severe sleep disturbed breathing was elicited...
journal_title：Journal of pediatric urology
pub_type： 杂志文章
doi：10.1016/j.jpurol.2009.08.009
更新日期：2010-06-01 00:00:00
abstract：INTRODUCTION:Parents making complex decisions about hypospadias surgery may experience anxiety and uncertainty related to multiple sources of information with questionable reliability and limited relevance to their concerns. OBJECTIVE:The purpose of this study was to identify knowledge gaps, information-seeking behavi...
journal_title：Journal of pediatric urology
pub_type： 杂志文章
doi：10.1016/j.jpurol.2020.01.008
更新日期：2020-04-01 00:00:00
abstract：:Priapism is a medical emergency. An idiopathic case can be a difficult clinical problem in the pediatric emergency room. This case highlights the successful use of penile irrigation and injection of phenylephrine in a 13-year-old boy with idiopathic ischemic priapism 12 h after sexual intercourse. ...
journal_title：Journal of pediatric urology
pub_type： 杂志文章
doi：10.1016/j.jpurol.2008.09.004
更新日期：2009-04-01 00:00:00
abstract：:The COVID pandemic has incited the rapid implementation of telehealth services. Through telemedicine, pediatric urologists can counsel children and their families about genitourinary tract conditions, while adhering to social distancing requirements and keeping families safe at home. With the accelerated use of teleme...
journal_title：Journal of pediatric urology
pub_type： 杂志文章
doi：10.1016/j.jpurol.2020.04.010
更新日期：2020-06-01 00:00:00
abstract：OBJECTIVE:Up to now, observation of familial undescended testis (UDT) has been confined to the description of individual cases. The aim of our study was to evaluate the frequency of a positive family history and of associated urological anomalies in family members, and to calculate the risk of newborn male individuals ...
journal_title：Journal of pediatric urology
pub_type： 杂志文章
doi：10.1016/j.jpurol.2005.04.005
更新日期：2005-12-01 00:00:00
abstract：OBJECTIVE:The objective of this study was to determine if later toilet training is associated with urge incontinence in children. METHODS:We used a case-control study design to yield level 2 evidence. RESULTS:Initiation of toilet training after 32 months of age was associated with urge incontinence (P=0.02). CONCLUS...
journal_title：Journal of pediatric urology
pub_type： 杂志文章
doi：10.1016/j.jpurol.2009.05.012
更新日期：2009-12-01 00:00:00
abstract：BACKGROUND:Congenital adrenal hyperplasia (CAH) consists of a group of diseases characterized by an enzyme deficiency, particularly 21-hydroxylase deficiency. The condition may present in the simple virilizing form or in the salt-wasting form, with varying degrees of genital ambiguity. The non-heterosexual orientation ...
journal_title：Journal of pediatric urology
pub_type： 杂志文章,评审
doi：10.1016/j.jpurol.2018.08.004
更新日期：2018-12-01 00:00:00
abstract：INTRODUCTION:There is ongoing debate about whether nocturnal enuresis (NE) is affected by the presence of attention deficit hyperactivity disorder (ADHD) in children. Clarifying this relationship could categorize them as a separate entity, potentially requiring a different management from enuretic children without ADHD...
journal_title：Journal of pediatric urology
pub_type： 杂志文章
doi：10.1016/j.jpurol.2017.07.002
更新日期：2018-02-01 00:00:00
abstract：INTRODUCTION:As there is only scarce information on the parents' view of the cosmetic outcome after hypospadias surgery we aimed to evaluate whether the results of the hypospadias objective penile evaluation (HOPE) score are transferable to parents satisfaction as measured by the pediatric penile perception score (PPPS...
journal_title：Journal of pediatric urology
pub_type： 杂志文章
doi：10.1016/j.jpurol.2015.10.010
更新日期：2016-02-01 00:00:00
abstract：OBJECTIVE:Congenital megaprepuce is a specific form of buried penis. Children affected by this malformation usually suffer from a subjective difficulty in voiding which is the main indication for early surgical correction. The aim of this study was to report a single center's 12-year experience in the treatment of mega...
journal_title：Journal of pediatric urology
pub_type： 杂志文章
doi：10.1016/j.jpurol.2012.10.010
更新日期：2013-12-01 00:00:00
abstract：INTRODUCTION:Management of poorly functioning kidneys with ureteropelvic junction obstruction (UPJO) is controversial, with some recommending direct nephrectomy and others direct pyeloplasty, and others temporary diversion. This study aimed to determine whether pyeloplasty is associated with higher complication rate th...
journal_title：Journal of pediatric urology
pub_type： 杂志文章,多中心研究
doi：10.1016/j.jpurol.2019.05.032
更新日期：2019-10-01 00:00:00
abstract：INTRODUCTION:Recurrent urinary tract infections (UTIs) are common in patients with neurogenic bladder (NGB) performing clean intermittent catheterization (CIC) treated with or without oral antibiotic prophylaxis. OBJECTIVE:The authors aim to determine if daily neomycin-polymyxin or gentamicin bladder instillations red...
journal_title：Journal of pediatric urology
pub_type： 杂志文章
doi：10.1016/j.jpurol.2018.12.001
更新日期：2019-04-01 00:00:00
abstract：OBJECTIVE:In the US, there has been an evolution in the practice of pediatric urology from a primary academic sub-specialty focused on reconstruction of major congenital genitorurinary abnormalities to a mixed academic and private practice that serves as the primary care giver for all pediatric urologic concerns. The e...
journal_title：Journal of pediatric urology
pub_type： 杂志文章
doi：10.1016/j.jpurol.2010.12.009
更新日期：2011-08-01 00:00:00
abstract：INTRODUCTION:Bladder calculi are a known complication of bladder augmentation. Open cystolithotomy remains the preferred option for treating large or multiple stones. Increasingly, however, minimal access techniques have been used. Reports of Mitrofanoff cystolitholapaxy are rare and have been limited to adults. This s...
journal_title：Journal of pediatric urology
pub_type： 杂志文章,多中心研究
doi：10.1016/j.jpurol.2018.02.024
更新日期：2018-10-01 00:00:00
abstract：BACKGROUND:An association has been found between lower urinary tract dysfunction (LUTD) and emotional and behavioral problems, particularly in cases of urinary incontinence. Other associated symptoms and the coexistence of functional constipation require further investigation. OBJECTIVE:To assess whether emotional and...
journal_title：Journal of pediatric urology
pub_type： 杂志文章,多中心研究
doi：10.1016/j.jpurol.2018.12.003
更新日期：2019-08-01 00:00:00
abstract：INTRODUCTION:Dorsal inlay graft urethroplasty using inner-face preputial graft was described as an adjunct method to the classic tubularized incised plate (TIP) urethroplasty, aiming at reducing the risk of neourethral stenosis. OBJECTIVES:To evaluate the impact of dorsal inlay grafting of preservable narrow plates, i...
journal_title：Journal of pediatric urology
pub_type： 杂志文章
doi：10.1016/j.jpurol.2019.05.002
更新日期：2019-08-01 00:00:00
abstract：INTRODUCTION:Minimally invasive surgery has become an important aspect of Pediatric Urology fellowship training. In 2014, the Accreditation Council for Graduate Medical Education published the Pediatric Urology Milestone Project as a metric of fellow proficiency in multiple facets of training, including laparoscopic/ro...
journal_title：Journal of pediatric urology
pub_type： 杂志文章
doi：10.1016/j.jpurol.2016.08.012
更新日期：2017-02-01 00:00:00
abstract：:End-stage renal disease is becoming a contemporary global concern with increasing prevalence. The available treatment strategies are limited to dialysis and renal transplantation. However, limited organ supply and autoimmune rejection are the shortcomings that limit widespread application of transplantation. Favorably...
journal_title：Journal of pediatric urology
pub_type： 杂志文章
doi：10.1016/j.jpurol.2018.01.008
更新日期：2018-04-01 00:00:00
