Evolving microbiology and treatment of extracavitary prosthetic graft infections.

Abstract:

:The authors report the microbiology and outcomes following an individualized treatment algorithm for extracavitary (EC) prosthetic graft infection, including the use of graft preservation and in situ graft replacement techniques. A retrospective 8-year review of 87 patients treated for EC prosthetic graft infections was carried out. The treatment algorithm included culture-specific antibiotic therapy, surgical site debridement with antibiotic bead placement, selected graft preservation with muscle flap coverage, or graft excision with in situ conduit replacement. Outcomes measured included death, limb loss, and recurrent infection. It was found that present-day management of EC prosthetic graft infections is associated with lower mortality and morbidity despite changes in microbiology and the increased application of graft preservation and in situ grafting treatments.

journal_name

Vasc Endovascular Surg

authors

Stone PA,Back MR,Armstrong PA,Brumberg RS,Flaherty SK,Johnson BL,Shames ML,Bandyk DF

doi

10.1177/1538574408322658

subject

Has Abstract

pub_date

2008-12-01 00:00:00

pages

537-44

issue

6

eissn

1538-5744

issn

1938-9116

pii

1538574408322658

journal_volume

42

pub_type

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