Technetium-99m-sestamibi scintigraphy in gynecological cancer imaging.

Abstract:

:A new diagnostic method, technetium-99m-sestamibi scintigraphy, and its potential use in gynecological oncology is described. The biochemical mechanisms of uptake and retention of technetium-99m-sestamibi in neoplastic cells are presented and the grounds for the potential use of the tracer in predicting the response to first-line chemotherapy in ovarian cancer patients are discussed. Based on the available literature data and on our own studies, the sensitivity and specificity of technetium-99m-sestamibi scintigraphy in ovarian cancer diagnosis are assessed, and the current place of this method among other functional imaging methods applied in gynecological oncology is discussed. Technetium-99m-sestamibi scintigraphy seems to provide an attractive alternative method to the expensive PET imaging, and can be easily performed in most hospitals. However, further studies in a larger series of patients are necessary before this method is widely applied.

journal_name

Eur J Gynaecol Oncol

authors

Stelmachów J,Timorek-Lemieszczuk A

subject

Has Abstract

pub_date

2008-01-01 00:00:00

pages

309-12

issue

4

eissn

0392-2936

issn

2709-0086

journal_volume

29

pub_type

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