Abstract:
PURPOSE:To retrospectively analyze whether adding a delayed high-resolution dedicated neck F-18 FDG positron emission tomography-computerized tomographic (PET-CT) imaging protocol in patients with recurrent differentiated thyroid cancer increases the number of abnormal foci within the neck. MATERIALS AND METHODS:Seventeen PET-CT studies from a total of 10 patients with suspected recurrent differentiated thyroid cancer between March 2003 and June 2004 were retrospectively reviewed. Each study included a whole body acquisition (WBA), followed by higher resolution dedicated neck acquisition (DNA). Two board-certified nuclear medicine physicians reviewed either the DNA or WBA for each study and recorded the number of abnormal foci, along with presence or absence of a soft tissue abnormality, and maximum standardized uptake value for each foci. Consensus review was used for all discrepancies. Statistical analysis was performed to determine whether there was a statistically significant increase in the number of studies demonstrating new abnormal foci with the addition of a DNA. RESULTS:Five of 17 studies demonstrated an increase in the number of abnormal foci with the addition of the DNA (P < 0.04). A total of 8 abnormal foci were noted on the WBA, 4 of which were within the neck. Eleven additional abnormal foci were seen on the DNA. All abnormal foci within the neck had corresponding soft tissue abnormalities except for one. CONCLUSION:Adding a higher resolution delayed DNA to the WBA for patients undergoing PET-CT imaging to detect recurrent thyroid cancer increases the number of abnormal sites of FDG accumulation.
journal_name
Clin Nucl Medjournal_title
Clinical nuclear medicineauthors
Davison JM,Stocker DJ,Montilla-Soler JL,Jurgens JS,Allen TW,Holley TS,Stack ALdoi
10.1097/RLU.0b013e31817792c9subject
Has Abstractpub_date
2008-07-01 00:00:00pages
464-8issue
7eissn
0363-9762issn
1536-0229pii
00003072-200807000-00003journal_volume
33pub_type
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journal_title:Clinical nuclear medicine
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journal_title:Clinical nuclear medicine
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