Acute diarrhea during azathioprine treatment of type I autoimmune hepatitis.

Abstract:

:Sporadic descriptions of acute onset of watery diarrhea within a few hours to a few weeks azathioprine administration beginning have been reported, particularly in inflammatory bowel disease patients. This article reports the case of a woman treated with azathioprine because of type I autoimmune hepatitis, who developed acute watery diarrhea after more than two months of therapy. In two occasions the patient reassumed the drug and in a few hours diarrhea recurred. Subsequent 6-mercaptopurine treatment was well tolerated, suggesting that the previous side-effect could be due to the nitroimidazole moiety of azathioprine.

journal_name

Minerva Med

journal_title

Minerva medica

authors

Fracchia M,Galatola G,Pera A,Foti M,Tabone M

subject

Has Abstract

pub_date

2008-04-01 00:00:00

pages

219-22

issue

2

eissn

0026-4806

issn

1827-1669

journal_volume

99

pub_type

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