Abstract:
STUDY OBJECTIVE:To investigate the effects of hypoxia-inducible factor (HIF) inhibitors, flotation agents, barriers, and a surfactant on pneumoperitoneum-enhanced adhesions in a laparoscopic mouse model. DESIGN:Prospective randomized trial (Canadian Task Force classification I). SETTING:Department of Obstetrics and Gynecology, University Hospital Gasthuisberg, Catholic University of Leuven. SUBJECTS:One hundred fourteen female BALB/c mice. INTERVENTIONS:Adhesions were induced during laparoscopy in BALB/c female mice. Pneumoperitoneum was maintained for 60 minutes with humidified CO(2). In 3 experiments the effects of HIF inhibitors such as 17-allylamino 17-demethoxygeldanamycin, radicicol, rapamycin, and wortmanin, flotation agents such as Hyskon and carboxymethylcellulose, barriers such as Hyalobarrier gel and SprayGel, and surfactant such as phospholipids were evaluated. MEASUREMENTS AND MAIN RESULTS:Adhesions were scored after 7 days during laparotomy. Adhesion formation decreased with the administration of wortmannin (p <.01), phospholipids (p <.01), Hyalobarrier Gel (p <.01), and SprayGel (p <.01). CONCLUSIONS:These experiments confirm the efficacy of barriers and phospholipids to separate or lubricate damaged surfaces. They also confirm the role of mesothelial hypoxia in this model by the efficacy of the HIF inhibitor wortmannin.
journal_name
J Minim Invasive Gynecoljournal_title
Journal of minimally invasive gynecologyauthors
Binda MM,Molinas CR,Bastidas A,Jansen M,Koninckx PRdoi
10.1016/j.jmig.2007.04.002subject
Has Abstractpub_date
2007-09-01 00:00:00pages
591-9issue
5eissn
1553-4650issn
1553-4669pii
S1553-4650(07)00154-9journal_volume
14pub_type
杂志文章abstract:OBJECTIVE:To determine whether accuracy of visual diagnosis of endometriosis at laparoscopy is determined by stage of disease. DESIGN:Prospective longitudinal cohort study (Canadian Task Force classification II-2). SETTING:Tertiary referral centers in three Australian states. PATIENTS:Of 1439 biopsy specimens, endom...
journal_title:Journal of minimally invasive gynecology
pub_type: 杂志文章
doi:10.1016/j.jmig.2013.04.017
更新日期:2013-11-01 00:00:00
abstract:OBJECTIVE:Laparoscopic uterine artery ligation may be performed during myomectomy or other uterine invasive procedures to reduce the amount of blood loss during surgery. In this video, the authors describe 3 different laparoscopic techniques to approach the uterine artery. DESIGN:Step-by-step video demonstration of 3 ...
journal_title:Journal of minimally invasive gynecology
pub_type: 杂志文章
doi:10.1016/j.jmig.2019.08.026
更新日期:2020-01-01 00:00:00
abstract::The most common mode of injury to the ureter is iatrogenic; however, injury during laparoscopic sterilization is rare. Although thermal ureteric injury during laparoscopic sterilization has been reported, to our knowledge, this is the first published report of ureteric injury caused by placement of a Filschie clip dur...
journal_title:Journal of minimally invasive gynecology
pub_type: 杂志文章
doi:10.1016/j.jmig.2009.01.011
更新日期:2009-05-01 00:00:00
abstract::A 33-year-old woman with a 2-year history of swelling and pain in her buttock and left thigh fluctuating with her menstrual cycle who was becoming progressively disabled was referred to the department of orthopedics. Magnetic resonance imaging (MRI) detected a left buttock lesion of 3 x 2 cm that was initially diagnos...
journal_title:Journal of minimally invasive gynecology
pub_type: 杂志文章
doi:10.1016/j.jmig.2008.09.619
更新日期:2009-01-01 00:00:00
abstract:STUDY OBJECTIVE:To determine the prevalence and pattern of opioid use in endometriosis and the characteristics of patients prescribed an opioid using medical insurance claims data. DESIGN:We performed a retrospective cohort analysis of data from the Truven MarketScan Commercial database for the period of January 1, 20...
journal_title:Journal of minimally invasive gynecology
pub_type: 杂志文章
doi:10.1016/j.jmig.2020.05.029
更新日期:2020-06-09 00:00:00
abstract:STUDY OBJECTIVE:To compare outcomes after minimally invasive surgery (MIS) vs open radical hysterectomy for early stage cervical cancer incorporating 2018 Federation of Gynecology and Obstetrics (FIGO) staging. DESIGN:A retrospective analysis. SETTING:A single teaching hospital. PATIENTS:Patients after radical hyste...
journal_title:Journal of minimally invasive gynecology
pub_type: 杂志文章
doi:10.1016/j.jmig.2020.07.021
更新日期:2020-07-28 00:00:00
abstract::Because it is minimally invasive, laparoscopic surgery is preferred over open surgery. However, it is often difficult to maintain an adequate surgical field during the procedure. As in open laparotomy, securing an adequate surgical field is important for adequate visualization. We evaluated the effectiveness and safet...
journal_title:Journal of minimally invasive gynecology
pub_type: 临床试验,杂志文章
doi:10.1016/j.jmig.2011.04.012
更新日期:2011-07-01 00:00:00
abstract::Ectopic pregnancy is commonly managed via either laparoscopic salpingostomy or salpingectomy. However, there is a proficiency gain curve in mastering these 2 surgical procedures, and an effective simulated model is essential for training students of gynecology. The objective of this study was to develop and evaluate a...
journal_title:Journal of minimally invasive gynecology
pub_type: 杂志文章
doi:10.1016/j.jmig.2011.06.020
更新日期:2011-11-01 00:00:00
abstract:STUDY OBJECTIVE:To estimate the effectiveness of unidirectional knotless barbed suture and continuous suture with intracorporeal knots in the repair of uterine wall defects during laparoscopic myomectomy. DESIGN:Randomized clinical study (Canadian Task Force Classification I). SETTING:Single-center study in a univers...
journal_title:Journal of minimally invasive gynecology
pub_type: 杂志文章,随机对照试验
doi:10.1016/j.jmig.2010.06.007
更新日期:2010-11-01 00:00:00
abstract:BACKGROUND:Laparoscopic colposuspension has been shown in some studies to have equivocal results as open colposuspension, and in addition to treating stress incontinence can also reduce anterior vaginal wall compartment prolapse, as described by Burch in 1961 [1]. STUDY OBJECTIVE:To demonstrate a novel modified techni...
journal_title:Journal of minimally invasive gynecology
pub_type: 杂志文章
doi:10.1016/j.jmig.2014.05.016
更新日期:2014-11-01 00:00:00
abstract:STUDY OBJECTIVE:To verify the efficacy and safety of minilaparotomy hysterectomy using a self-retaining elastic abdominal retractor. DESIGN:Retrospective study (Canadian Task Force classification II-3). SETTING:Private hospital, department of obstetrics and gynecology. PATIENTS:One-hundred-fifty women, age 37 to 76 ...
journal_title:Journal of minimally invasive gynecology
pub_type: 杂志文章
doi:10.1016/j.jmig.2006.06.030
更新日期:2007-01-01 00:00:00
abstract::Our objective was to evaluate complications reported to the Manufacturer and User Facility Device Experience (MAUDE) database and to look for trends of complications among various endometrial ablation devices. This database was not intended to be used either to evaluate rates of adverse events or to compare adverse ev...
journal_title:Journal of minimally invasive gynecology
pub_type: 杂志文章,评审
doi:10.1016/j.jmig.2007.05.008
更新日期:2007-07-01 00:00:00
abstract::Giant cervical polyps are characterized by an unusually large size and appear clinically as malignant. A 35-year-old woman had increased vaginal discharge and lower abdominal discomfort. At examination, a fist-sized, hard, consistent mass was found in the vagina. Pelvic magnetic resonance imaging revealed a 12.6 x 8-c...
journal_title:Journal of minimally invasive gynecology
pub_type: 杂志文章
doi:10.1016/j.jmig.2009.04.003
更新日期:2009-07-01 00:00:00
abstract::Ureteral injuries are known complications of pelvic surgery. The incidence is 0.5% to 3%, and approximately one-third of these cases are not identified or corrected intraoperatively. It is critical to recognize and repair these injuries intraoperatively to decrease morbidity and prevent further complications, such as ...
journal_title:Journal of minimally invasive gynecology
pub_type: 杂志文章,评审
doi:10.1016/j.jmig.2006.10.023
更新日期:2007-05-01 00:00:00
abstract::Enhanced recovery after surgery (ERAS), or "fast-track" protocol, aims to minimize the physiologic stress of surgery and optimize the rehabilitation of patients. However, there is limited data in obstetrics and gynecology. We reviewed the published literature on ERAS programs in gynecology to evaluate the outcomes and...
journal_title:Journal of minimally invasive gynecology
pub_type: 杂志文章
doi:10.1016/j.jmig.2018.12.010
更新日期:2019-02-01 00:00:00
abstract:STUDY OBJECTIVE:We sought to estimate effectiveness of transdermal scopolamine to prevent postoperative nausea and vomiting after gynecologic laparoscopy. DESIGN:Patients were randomized to receive preoperative transdermal scopolamine or placebo. Main outcome measure was incidence of nausea during the first 24 hours p...
journal_title:Journal of minimally invasive gynecology
pub_type: 杂志文章,随机对照试验
doi:10.1016/j.jmig.2007.08.616
更新日期:2008-01-01 00:00:00
abstract:STUDY OBJECTIVE:To determine whether completion rates of salpingostomy for tubal ectopic pregnancy are compromised by initial medical management with methotrexate (MTX). DESIGN:Retrospective cohort study. SETTING:Single academic hospital system. PATIENTS:Patients requiring surgery for ectopic pregnancy between 2006 ...
journal_title:Journal of minimally invasive gynecology
pub_type: 杂志文章
doi:10.1016/j.jmig.2020.09.003
更新日期:2020-09-07 00:00:00
abstract:BACKGROUND:Video seems advantageous over traditional text as an educational tool in conceptually-based procedures such as laparoscopy. However, this has never been tested directly. OBJECTIVE:The purpose of this study was to compare the use of text versus video as an educational tool for laparoscopic training, through ...
journal_title:Journal of minimally invasive gynecology
pub_type: 杂志文章,随机对照试验
doi:10.1016/j.jmig.2009.02.011
更新日期:2009-07-01 00:00:00
abstract:STUDY OBJECTIVE:To determine the prevalence of adenomyosis and deep adenomyosis after NovaSure (Hologic Inc., Newark, DE) endometrial ablation in hysterectomy specimens after NovaSure endometrial ablation failure. DESIGN:Prospective observational study (Canadian Task Force classification II-2). SETTING:The TweeSteden...
journal_title:Journal of minimally invasive gynecology
pub_type: 杂志文章
doi:10.1016/j.jmig.2014.10.006
更新日期:2015-02-01 00:00:00
abstract:STUDY OBJECTIVE:To evaluate the efficacy of intrauterine lidocaine instillation in reducing patient discomfort during saline solution infusion sonohysterography (SIS). DESIGN:A double-blinded, randomized, controlled trial (Canadian Task Force classification I). SETTING:Suleyman Demirel University School of Medicine, ...
journal_title:Journal of minimally invasive gynecology
pub_type: 杂志文章,随机对照试验
doi:10.1016/j.jmig.2007.02.007
更新日期:2007-05-01 00:00:00
abstract:STUDY OBJECTIVE:To examine whether our new reporting system and mandatory fluid-balance form could improve the communication and awareness within the surgical team and therefore the safety of hysteroscopic operations. DESIGN:A case-control study (Canadian Task Force classification II-2). SETTING:An endoscopic gynecol...
journal_title:Journal of minimally invasive gynecology
pub_type: 杂志文章
doi:10.1016/j.jmig.2017.06.014
更新日期:2017-01-01 00:00:00
abstract:STUDY OBJECTIVE:We sought to determine whether relief of chronic pelvic pain symptoms with hormonal treatment is predictive of presence or absence of endometriosis or location of endometriosis within the pelvis. DESIGN:A retrospective, chart review (Canadian Task Force classification II-3). SETTING:A private practice...
journal_title:Journal of minimally invasive gynecology
pub_type: 杂志文章
doi:10.1016/j.jmig.2007.09.002
更新日期:2008-01-01 00:00:00
abstract::Hemangiomas are known to be common benign tumors. However, hemangiomas of female genital organs are very rare. Furthermore, a retroperitoneal hemangioma arising from ovarian vessels has never been reported. Here we report a case of a 29-year-old woman with a retroperitoneal cavernous hemangioma arising from the ovaria...
journal_title:Journal of minimally invasive gynecology
pub_type: 杂志文章
doi:10.1016/j.jmig.2009.07.017
更新日期:2009-11-01 00:00:00
abstract:STUDY OBJECTIVE:To discuss our clinical and surgical experience with 30 cases of ureteral endometriosis. DESIGN:Retrospective analysis (Canadian Task Force classification II-3). SETTING:Tertiary care university hospital. PATIENTS:Records were assessed for all patients who underwent laparoscopic surgery for deep infi...
journal_title:Journal of minimally invasive gynecology
pub_type: 杂志文章
doi:10.1016/j.jmig.2008.03.005
更新日期:2008-07-01 00:00:00
abstract:BACKGROUND AND PURPOSE:Laparoscopic extravesical ureteroneocystostomy is an infrequently described technique. Our aim is to describe five cases where we used the intracorporeal freehand suturing technique successfully for performing laparoscopic extravesical transperitoneal ureteral reimplantation with psoas hitch. We ...
journal_title:Journal of minimally invasive gynecology
pub_type: 杂志文章
doi:10.1016/j.jmig.2006.03.016
更新日期:2006-07-01 00:00:00
abstract:STUDY OBJECTIVE:To describe the perioperative outcomes of various modes of myomectomy (abdominal [AM], laparoscopic [LM], or robotic [RM]) in cases of extreme myoma burden. DESIGN:Retrospective cohort study (Canadian Task Force classification II-2). SETTING:A tertiary academic center in Boston, Massachusetts. PATIEN...
journal_title:Journal of minimally invasive gynecology
pub_type: 杂志文章
doi:10.1016/j.jmig.2018.10.022
更新日期:2019-01-01 00:00:00
abstract:STUDY OBJECTIVE:To investigate the effect of uterine weight on the mode of hysterectomy and on perioperative outcomes and to explore how the increasing experience in endoscopic techniques influenced our choice of surgical approach to hysterectomy to treat benign conditions. DESIGN:Retrospective analysis (Canadian Task...
journal_title:Journal of minimally invasive gynecology
pub_type: 杂志文章
doi:10.1016/j.jmig.2013.02.009
更新日期:2013-07-01 00:00:00
abstract::Endometriosis affects a significant proportion of reproductive-aged women. The impact of the disease on ovarian function is an important consideration when planning treatment in women who want to retain the potential of future childbearing. This review will specifically address the association between endometriomas an...
journal_title:Journal of minimally invasive gynecology
pub_type: 杂志文章,评审
doi:10.1016/j.jmig.2013.09.012
更新日期:2014-03-01 00:00:00
abstract:STUDY OBJECTIVE:To compare reduction of pain after laparoscopy for ablation or excision of endometriosis. DESIGN:Prospective, randomized, double-blind study (Canadian Task Force classification I). SETTING:Endometriosis and pelvic pain clinic at a university teaching hospital. PATIENTS:Women of reproductive age with ...
journal_title:Journal of minimally invasive gynecology
pub_type: 杂志文章,随机对照试验
doi:10.1016/j.jmig.2014.04.002
更新日期:2014-11-01 00:00:00
abstract:STUDY OBJECTIVE:The primary objective was to compare carbon dioxide (CO2) absorption rates in patients undergoing gynecologic laparoscopy with a standard versus valveless insufflation system (AirSeal; ConMed, Utica, NY) at intra-abdominal pressures (IAPs) of 10 and 15 mm Hg. Secondary objectives were assessment of surg...
journal_title:Journal of minimally invasive gynecology
pub_type: 杂志文章,随机对照试验
doi:10.1016/j.jmig.2019.05.005
更新日期:2020-01-01 00:00:00