Abstract:
BACKGROUND:The hypersensitive necrosis response (HR) of resistant plants to avirulent pathogens is a form of programmed cell death in which the plant sacrifices a few cells under attack, restricting pathogen growth into adjacent healthy tissues. In spite of the importance of this defense response, relatively little is known about the plant components that execute the cell death program or about its regulation in response to pathogen attack. RESULTS:We isolated the edr2-6 mutant, an allele of the previously described edr2 mutants. We found that edr2-6 exhibited an exaggerated chlorosis and necrosis response to attack by three pathogens, two powdery mildew and one downy mildew species, but not in response to abiotic stresses or attack by the bacterial leaf speck pathogen. The chlorosis and necrosis did not spread beyond inoculated sites suggesting that EDR2 limits the initiation of cell death rather than its spread. The pathogen-induced chlorosis and necrosis of edr2-6 was correlated with a stimulation of the salicylic acid defense pathway and was suppressed in mutants deficient in salicylic acid signaling. EDR2 encodes a novel protein with a pleckstrin homology and a StAR transfer (START) domain as well as a plant-specific domain of unknown function, DUF1336. The pleckstrin homology domain binds to phosphatidylinositol-4-phosphate in vitro and an EDR2:HA:GFP protein localizes to endoplasmic reticulum, plasma membrane and endosomes. CONCLUSION:EDR2 acts as a negative regulator of cell death, specifically the cell death elicited by pathogen attack and mediated by the salicylic acid defense pathway. Phosphatidylinositol-4-phosphate may have a role in limiting cell death via its effect on EDR2. This role in cell death may be indirect, by helping to target EDR2 to the appropriate membrane, or it may play a more direct role.
journal_name
BMC Plant Bioljournal_title
BMC plant biologyauthors
Vorwerk S,Schiff C,Santamaria M,Koh S,Nishimura M,Vogel J,Somerville C,Somerville Sdoi
10.1186/1471-2229-7-35subject
Has Abstractpub_date
2007-07-06 00:00:00pages
35issn
1471-2229pii
1471-2229-7-35journal_volume
7pub_type
杂志文章abstract:BACKGROUND:The Hessian fly (Mayetiola destructor), belonging to the gall midge family (Cecidomyiidae), is a devastating pest of wheat (Triticum aestivum) causing significant yield losses. Despite identification and characterization of numerous Hessian fly-responsive genes and associated biological pathways involved in ...
journal_title:BMC plant biology
pub_type: 杂志文章
doi:10.1186/s12870-019-2058-6
更新日期:2019-10-22 00:00:00
abstract:BACKGROUND:Saccharina japonica is an important commercial brown seaweed, its main product is alginate, which is used in food, textile and by the cosmetic and pharmaceutical industries. GDP-mannose dehydrogenase (GMD) is the key enzyme involved in the synthesis of alginate. However, little is known about GMD in S. japon...
journal_title:BMC plant biology
pub_type: 杂志文章
doi:10.1186/s12870-016-0750-3
更新日期:2016-03-08 00:00:00
abstract:BACKGROUND:Paphiopedilum is a horticulturally and ecologically important genus of ca. 80 species of lady's slipper orchids native to Southeast Asia. These plants have long been of interest regarding their chromosomal evolution, which involves a progressive aneuploid series based on either fission or fusion of centromer...
journal_title:BMC plant biology
pub_type: 杂志文章
doi:10.1186/1471-2229-11-126
更新日期:2011-09-12 00:00:00
abstract:BACKGROUND:The tomato kinase Pto confers resistance to bacterial speck disease caused by Pseudomonas syringae pv. tomato in a gene for gene manner. Upon recognition of specific avirulence factors the Pto kinase activates multiple signal transduction pathways culminating in induction of pathogen defense. The soluble cyt...
journal_title:BMC plant biology
pub_type: 杂志文章
doi:10.1186/1471-2229-6-22
更新日期:2006-10-06 00:00:00
abstract:BACKGROUND:In Quercus suber, cork oak, a Mediterranean forest tree of economic and social interest, rapid production of isogenic lines and clonal propagation of elite genotypes have been achieved by developing in vitro embryogenesis from microspores and zygotic embryos respectively. Despite its high potential in tree b...
journal_title:BMC plant biology
pub_type: 杂志文章
doi:10.1186/s12870-014-0224-4
更新日期:2014-08-21 00:00:00
abstract:BACKGROUND:The dispensable maize (Zea mays L.) B chromosome is highly heterochromatic and widely believed to be devoid of functional genes. Although low-copy B chromosome causes no obvious phenotype variation, its existence might influence A genome gene expression. Previous studies suggested that B chromosomes are evol...
journal_title:BMC plant biology
pub_type: 杂志文章
doi:10.1186/s12870-016-0775-7
更新日期:2016-04-16 00:00:00
abstract:BACKGROUND:Maize is one of the most important crops in the world. With the exponentially increasing population and the need for ever increased food and feed production, an increased yield of maize grain (as well as rice, wheat and other grains) will be critical. Maize grain development is understood from the perspectiv...
journal_title:BMC plant biology
pub_type: 杂志文章
doi:10.1186/1471-2229-13-19
更新日期:2013-02-04 00:00:00
abstract:BACKGROUND:Flavonoid biosynthesis is strongly influenced by phytohormones. For example, methyl jasmonate (MeJA) enhances the flavonoid accumulation in pear. However, the molecular mechanism underlying the MeJA-induced flavonoid biosynthesis in pear is largely uncharacterized. Therefore, the transcriptome of pear calli ...
journal_title:BMC plant biology
pub_type: 杂志文章
doi:10.1186/s12870-020-02606-x
更新日期:2020-08-25 00:00:00
abstract:BACKGROUND:Recent genome sequencing enables mega-base scale comparisons between related genomes. Comparisons between animals, plants, fungi, and bacteria demonstrate extensive synteny tempered by rearrangements. Within the legume plant family, glimpses of synteny have also been observed. Characterizing syntenic relatio...
journal_title:BMC plant biology
pub_type: 杂志文章
doi:10.1186/1471-2229-5-15
更新日期:2005-08-15 00:00:00
abstract:BACKGROUND:DNA ligase enzymes catalyse the joining of adjacent polynucleotides and as such play important roles in DNA replication and repair pathways. Eukaryotes possess multiple DNA ligases with distinct roles in DNA metabolism, with clear differences in the functions of DNA ligase orthologues between animals, yeast ...
journal_title:BMC plant biology
pub_type: 杂志文章
doi:10.1186/1471-2229-9-79
更新日期:2009-06-26 00:00:00
abstract:BACKGROUND:Nitrate (NO3-) is the major source of nitrogen (N) for higher plants aside from its function in transducing the N signaling. Improving N use efficiency of crops has been an effective strategy for promotion of the sustainable agriculture worldwide. The regulatory pathways associating with N uptake and the cor...
journal_title:BMC plant biology
pub_type: 杂志文章
doi:10.1186/s12870-018-1374-6
更新日期:2018-08-13 00:00:00
abstract:BACKGROUND:Legumes have the unique capacity to undergo two important root endosymbioses: the root nodule symbiosis and the arbuscular mycorrhizal symbiosis. Medicago truncatula is widely used to unravel the functions of genes during these root symbioses. Here we describe the development of an artificial microRNA (amiR)...
journal_title:BMC plant biology
pub_type: 杂志文章
doi:10.1186/1471-2229-13-82
更新日期:2013-05-16 00:00:00
abstract:BACKGROUND:Long terminal repeat (LTR) retrotransposons are highly abundant in plant genomes and require transcriptional activity for their proliferative mode of replication. These sequences exist in plant genomes as diverse sublineages within the main element superfamilies (i.e., gypsy and copia). While transcriptional...
journal_title:BMC plant biology
pub_type: 杂志文章
doi:10.1186/s12870-017-1223-z
更新日期:2018-01-05 00:00:00
abstract:BACKGROUND:Haematococcus lacustris is an ideal source of astaxanthin (AST), which is stored in oil bodies containing esterified AST (EAST) and triacylglycerol (TAG). Diacylglycerol acyltransferases (DGATs) catalyze the last step of acyl-CoA-dependent TAG biosynthesis and are also considered as crucial enzymes involved ...
journal_title:BMC plant biology
pub_type: 杂志文章
doi:10.1186/s12870-020-02794-6
更新日期:2021-01-06 00:00:00
abstract:BACKGROUND:ANGUSTIFOLIA (AN), one of the CtBP family proteins, plays a major role in microtubule-dependent cell morphogenesis. Microarray analysis of mammalian AN homologs suggests that AN might function as a transcriptional activator and regulator of a wide range of genes. Genetic characterization of AN mutants sugges...
journal_title:BMC plant biology
pub_type: 杂志文章
doi:10.1186/1471-2229-13-79
更新日期:2013-05-14 00:00:00
abstract:BACKGROUND:Plant lipid transfer proteins (LTPs) assemble a family of small (7-9 kDa) ubiquitous cationic proteins with an ability to bind and transport lipids as well as participate in various physiological processes including defense against phytopathogens. They also form one of the most clinically relevant classes of...
journal_title:BMC plant biology
pub_type: 杂志文章
doi:10.1186/s12870-016-0792-6
更新日期:2016-04-30 00:00:00
abstract:BACKGROUND:Sec18p/N-ethylmaleimide-sensitive factor (NSF) is a conserved eukaryotic ATPase, which primarily functions in vesicle membrane fusion from yeast to human. However, the function of the OsSec18 gene, a homologue of NSF in rice, remains unknown. RESULTS:In the present study, we investigated the function of OsS...
journal_title:BMC plant biology
pub_type: 杂志文章
doi:10.1186/s12870-014-0324-1
更新日期:2015-02-17 00:00:00
abstract:BACKGROUND:Salt stress is a major challenge for growth and development of plants. The mangrove tree Avicennia officinalis has evolved salt tolerance mechanisms such as salt secretion through specialized glands on its leaves. Although a number of structural studies on salt glands have been done, the molecular mechanism ...
journal_title:BMC plant biology
pub_type: 杂志文章
doi:10.1186/s12870-014-0291-6
更新日期:2014-11-18 00:00:00
abstract:BACKGROUND:Angiosperm sex chromosomes, where present, are generally recently evolved. The key step in initiating the development of sex chromosomes from autosomes is the establishment of a sex-determining locus within a region of non-recombination. To better understand early sex chromosome evolution, it is important to...
journal_title:BMC plant biology
pub_type: 杂志文章
doi:10.1186/s12870-019-1766-2
更新日期:2019-04-30 00:00:00
abstract:BACKGROUND:Leaves of Poaceae have a unique morphological feature: they consist of a proximal sheath and a distal blade separated by a ligular region. The sheath provides structural support and protects young developing leaves, whereas the main function of the blade is photosynthesis. The auricles allow the blade to til...
journal_title:BMC plant biology
pub_type: 杂志文章
doi:10.1186/s12870-019-1635-z
更新日期:2019-02-15 00:00:00
abstract:BACKGROUND:The RAD21 cohesin plays, besides its well-recognised role in chromatid cohesion, a role in DNA double strand break (dsb) repair. In Arabidopsis there are three RAD21 paralog genes (AtRAD21.1, AtRAD21.2 and AtRAD21.3), yet only AtRAD21.1 has been shown to be required for DNA dsb damage repair. Further investi...
journal_title:BMC plant biology
pub_type: 杂志文章
doi:10.1186/s12870-014-0353-9
更新日期:2014-12-16 00:00:00
abstract:BACKGROUND:Cytokinin Response Factors (CRFs) are a small subset of AP2/ERF transcription factor genes shown in Arabidopsis to regulate leaf development as part of the cytokinin signal transduction pathway. This study examines the phylogenetic distribution of CRF genes in other plant species, and attempts to identify th...
journal_title:BMC plant biology
pub_type: 杂志文章
doi:10.1186/1471-2229-10-74
更新日期:2010-04-26 00:00:00
abstract:BACKGROUND:Heavy metal pollution in crop fields is one of the major issues in sustainable agriculture production. To improve crop growth and reduce the toxic effects of metals is an ideal strategy. Understanding the resilience of gibberellins producing endophytic fungi associated with crop plants in metal contaminated ...
journal_title:BMC plant biology
pub_type: 杂志文章
doi:10.1186/1471-2229-13-86
更新日期:2013-05-31 00:00:00
abstract:BACKGROUND:Glutamine synthetase (GS) acts as a key enzyme in plant nitrogen (N) metabolism. It is important to understand the regulation of GS expression in plant. Promoters can initiate the transcription of its downstream gene. Eichhornia crassipes is a most prominent aquatic invasive plant, which has negative effects...
journal_title:BMC plant biology
pub_type: 杂志文章
doi:10.1186/s12870-021-02832-x
更新日期:2021-01-29 00:00:00
abstract:BACKGROUND:Multiple hybridization events gave rise to pentaploid dogroses which can reproduce sexually despite their uneven ploidy level by the unique canina meiosis. Two homologous chromosome sets are involved in bivalent formation and are transmitted by the haploid pollen grains and the tetraploid egg cells. In addit...
journal_title:BMC plant biology
pub_type: 杂志文章
doi:10.1186/1471-2229-11-37
更新日期:2011-02-23 00:00:00
abstract:BACKGROUND:Hydrogen gas (H2) is hypothesised to play a role in plants that are coping with stresses by regulating signal transduction and gene expression. Although the beneficial role of H2 in plant tolerance to cadmium (Cd) has been investigated previously, the corresponding mechanism has not been elucidated. In this ...
journal_title:BMC plant biology
pub_type: 杂志文章
doi:10.1186/s12870-020-2272-2
更新日期:2020-02-04 00:00:00
abstract:BACKGROUND:Arbuscular mycorrhizal (AM) symbiosis is the most widespread association between plant roots and fungi in natural and agricultural ecosystems. This work investigated the influence of mycorrhization on the economically relevant part of the tomato plant, by analyzing its impact on the physiology of the fruit. ...
journal_title:BMC plant biology
pub_type: 杂志文章
doi:10.1186/1471-2229-12-44
更新日期:2012-03-27 00:00:00
abstract:BACKGROUND:While there is now a significant body of research correlating apple (Malus x domestica) fruit softening with the cell wall hydrolase ENDO-POLYGALACTURONASE1 (PG1), there is currently little knowledge of its physiological effects in planta. This study examined the effect of down regulation of PG1 expression i...
journal_title:BMC plant biology
pub_type: 杂志文章
doi:10.1186/1471-2229-12-129
更新日期:2012-08-02 00:00:00
abstract:BACKGROUND:Sesquiterpene lactones are characteristic metabolites of Asteraceae (or Compositae) which often display potent bioactivities and are sequestered in specialized organs such as laticifers, resin ducts, and trichomes. For characterization of sunflower sesquiterpene synthases we employed a simple method to isola...
journal_title:BMC plant biology
pub_type: 杂志文章
doi:10.1186/1471-2229-9-86
更新日期:2009-07-06 00:00:00
abstract:BACKGROUND:The identification of QTL involved in heterosis formation is one approach to unravel the not yet fully understood genetic basis of heterosis - the improved agronomic performance of hybrid F1 plants compared to their inbred parents. The identification of candidate genes underlying a QTL is important both for ...
journal_title:BMC plant biology
pub_type: 杂志文章,meta分析
doi:10.1186/1471-2229-14-88
更新日期:2014-04-02 00:00:00