Abstract：
:Medetomidine, an antifouling candidate, was investigated for its effects on cytochrome P4501A (CYP1A) activity in fish. Rainbow trout (Oncorhynchus mykiss), turbot (Psetta maxima), and Atlantic cod (Gadus morhua) were exposed to medetomidine either via i.p. injection (<5 micromol (1mg)/kg) or via water (<50 nM). Enzyme activity was measured as ethoxyresorufin-O-deethylase (EROD) activity in liver microsomes. There was a small (2-7-fold) increase in EROD activity in rainbow trout. In turbot, EROD activity increased (4-fold) after injection, while a non-significant (50%) decrease was observed after water exposure. No effects on EROD activities were observed in Atlantic cod. In vitro inhibition studies of EROD activities in liver microsomes from all three species showed that medetomidine was a very potent CYP1A inhibitor. Thus, median inhibition values (IC(50)) were 35+/-10nM for rainbow trout, 47+/-17 nM for turbot, and 111+/-70 nM for Atlantic cod. These observed effects suggest that medetomidine interferes with CYP1A-dependent metabolism of xenobiotics in these fish species.
journal_name
Ecotoxicol Environ Safjournal_title
Ecotoxicology and environmental safetyauthors
Lennquist A,Celander MC,Förlin Ldoi
10.1016/j.ecoenv.2007.05.004subject
Has Abstractpub_date
2008-01-01 00:00:00pages
74-9issue
1eissn
0147-6513issn
1090-2414pii
S0147-6513(07)00107-8journal_volume
69pub_type
杂志文章abstract：:Radon gas is noble gas formed from the normal radioactive decay series of 238U. Uranium is present in almost all rocks but enriched in silica-rich rocks like granites, gneisses, schists, volcanics, pegmatites, migmatites. The study area extends over metamorphic, volcanic, and clastic sedimentary rocks. Soil radon was ...
journal_title：Ecotoxicology and environmental safety
pub_type： 杂志文章
doi：10.1016/j.ecoenv.2020.111466
更新日期：2021-01-15 00:00:00
abstract：:Effects of carbofuran commercial formulation on oxidative stress parameters were studied in carps (Cyprinus carpio) exposed to 50µg/L for 7 and 30 days under rice field and laboratory conditions. Thiobarbituric acid reactive substance (TBARS) levels were increased in the brain of fish after 7 and 30 days under rice fi...
journal_title：Ecotoxicology and environmental safety
pub_type： 杂志文章
doi：10.1016/j.ecoenv.2013.12.012
更新日期：2014-03-01 00:00:00
abstract：:Phytoremediation and bioremediation are site-specific processes, and feasibility studies should be performed as an initial step in scaling-up these processes. Soil microcosms can be a useful tool for investigating the efficiency of remediation alternatives under realistic conditions. In the present study, the degradat...
journal_title：Ecotoxicology and environmental safety
pub_type： 杂志文章
doi：10.1016/j.ecoenv.2011.08.009
更新日期：2011-11-01 00:00:00
abstract：:In this study, six alkyl esters of p-hydroxybenzoic acids (parabens) and their metabolite, 4-hydroxybenzoic acid (p-HB) were simultaneously determined in surface water and sediment from the Yellow River and the Huai River in Henan Province, China. Concentrations of ∑parabens in surface water were 3.31-55.2 ng/L in the...
journal_title：Ecotoxicology and environmental safety
pub_type： 杂志文章
doi：10.1016/j.ecoenv.2019.01.102
更新日期：2019-05-15 00:00:00
abstract：:Experimental bioassays are currently used in ecotoxicology and environmental toxicology to provide information for risk assessment evaluation of new chemicals and to investigate their effects and mechanisms of action; in addition, ecotoxicological models are used for the detection, control, and monitoring of the prese...
journal_title：Ecotoxicology and environmental safety
pub_type： 杂志文章
doi：10.1016/j.ecoenv.2003.09.001
更新日期：2004-05-01 00:00:00
abstract：:Cladoceran are animals of significant importance to freshwater bodies such that changes in their populations may result in drastic shifts in the food web. Numerous studies have investigated the effects of toxicants, and the effects of chemical and physical habitat changes to these animals. Most of these studies invest...
journal_title：Ecotoxicology and environmental safety
pub_type： 杂志文章
doi：10.1016/j.ecoenv.2016.10.018
更新日期：2017-01-01 00:00:00
abstract：:There have been efforts to acquire information on the carcinogenic hazards of environmental materials to which humans are exposed since the earliest indications that chemicals can induce cancer in man. N-Nitroso compounds represent a major class of important chemical carcinogens and mutagens that have been implicated ...
journal_title：Ecotoxicology and environmental safety
pub_type： 杂志文章,评审
doi：10.1016/0147-6513(77)90034-3
更新日期：1977-09-01 00:00:00
abstract：:An increasing input rate of rare earth elements in the environment is expected because of the intense extraction of such elements form their ores to face human technological needs. In this study Lemna minor L. plants were grown under laboratory conditions and treated with increasing concentrations of cerium (Ce) ions ...
journal_title：Ecotoxicology and environmental safety
pub_type： 杂志文章
doi：10.1016/j.ecoenv.2018.07.113
更新日期：2018-11-15 00:00:00
abstract：:The aim of the present work was to examine the inter-relationship between elements in human hair depending on gender. In the whole population, the following groups of correlated elements were identified: alkaline earth metals (Ba, Ca, Mg, Sr), major microelements (Cu, Mn, Si, Zn) and La, Ti. In the subpopulation of ma...
journal_title：Ecotoxicology and environmental safety
pub_type： 杂志文章
doi：10.1016/j.ecoenv.2010.09.004
更新日期：2010-11-01 00:00:00
abstract：:The study evaluated contamination of fish by mercury in two important Czech water reservoirs, Orlík and Kamýk, which receive water from the whole watershed of Otava and Vltava rivers. Contamination of these reservoirs reflects the situation in southern and western Bohemia. Six environmentally representative sites were...
journal_title：Ecotoxicology and environmental safety
pub_type： 杂志文章
doi：10.1006/eesa.1999.1783
更新日期：1999-07-01 00:00:00
abstract：:Polysaccharides are the main components of plant cell walls in which they make an important contribution to cadmium (Cd) fixation. However, knowledge regarding the role of root cell wall polysaccharides in Cd accumulation in low-Cd cultivars is limited. Here, we compared the differences in root cell wall polysaccharid...
journal_title：Ecotoxicology and environmental safety
pub_type： 杂志文章
doi：10.1016/j.ecoenv.2020.110369
更新日期：2020-05-01 00:00:00
abstract：:In the present study, we investigated the role of calcite, i.e., microbiologically-induced precipitate by ureolytic Trichoderma sp. MG, in remediation of soils contaminated with arsenic (As) and lead (Pb). The fungus tolerates high concentrations of As (500 mg/L) and Pb (650 mg/L). The effects of three factors, i.e., ...
journal_title：Ecotoxicology and environmental safety
pub_type： 杂志文章
doi：10.1016/j.ecoenv.2019.03.034
更新日期：2019-06-15 00:00:00
abstract：:Presence of missing data points in datasets is among main challenges in handling the toxicological data for nanomaterials. As the processing of missing data is an important part of data analysis, we have introduced a read-across approach that uses a combination of supervised and unsupervised machine learning technique...
journal_title：Ecotoxicology and environmental safety
pub_type： 杂志文章
doi：10.1016/j.ecoenv.2019.109733
更新日期：2019-12-15 00:00:00
abstract：:Rainbow trout (Onchorynchus mykiss) and Japanese medaka (Oryzias latipes) were exposed to the hypolipidemic drug gemfibrozil, a known rodent peroxisome proliferator. Trout were injected (i.p.) daily for 2 weeks at doses of 0, 46, 87, or 152 mg/kg/day. Medaka were exposed to the nominal concentrations of 0, 1.25, 2.5, ...
journal_title：Ecotoxicology and environmental safety
pub_type： 杂志文章
doi：10.1016/0147-6513(94)90026-4
更新日期：1994-10-01 00:00:00
abstract：:Deltamethrin is a commonly used pyrethroid pesticide. Vitamin E is a antioxidant that plays an important role in protecting cells against toxicity by inactivating free radicals generated following pesticides exposure. Therefore, in the present study, it was evaluated whether deltamethrin induced changes on the fatty a...
journal_title：Ecotoxicology and environmental safety
pub_type： 杂志文章
doi：10.1016/j.ecoenv.2012.04.012
更新日期：2012-06-01 00:00:00
abstract：:The mining and processing of nickel ores from tropical regions contributes 40% of the global supply. The potential impact of these activities on tropical marine ecosystems is poorly understood. Due to the lack of ecotoxicity data for tropical marine species, there is currently no available water quality guideline valu...
journal_title：Ecotoxicology and environmental safety
pub_type： 杂志文章
doi：10.1016/j.ecoenv.2018.05.010
更新日期：2018-09-15 00:00:00
abstract：:Studies showed that DDT levels were still high in Tianjin, China, even though its use was banned in 1983. To estimate current risk of DDT to human health in Tianjin area, a non-steady-state (Level IV) multimedia fugacity model was used to simulate the fate and transfer of p,p'-DDT before and after the ban. The ordinar...
journal_title：Ecotoxicology and environmental safety
pub_type： 杂志文章
doi：10.1016/j.ecoenv.2005.06.003
更新日期：2006-02-01 00:00:00
abstract：:A novel, green, facile and dual turn-off/on sensor for detection of Hg2+ and I- was developed based on carbon dots. Carbon dots were synthesized from citric acid, urea, and thiourea by microwave-assisted method. The size of the carbon dots (CDs) was about 10 nm and the synthesized CDs showed a strong emission at 523 n...
journal_title：Ecotoxicology and environmental safety
pub_type： 杂志文章
doi：10.1016/j.ecoenv.2018.01.059
更新日期：2018-05-30 00:00:00
abstract：:Some drinks containing natural products with stimulant properties are highly consumed among young adults. The market for these drinks has increased in past years around the globe, and, although they might be harmless, overdoses or combination of these with other drinks could be harmful to the health of some consumers ...
journal_title：Ecotoxicology and environmental safety
pub_type： 杂志文章
doi：10.1006/eesa.2001.2213
更新日期：2002-09-01 00:00:00
abstract：:The contamination and distribution of polychlorinated dibenzo-p-dioxins and dibenzofurans (PCDD/Fs) from two agricultural fields of a heavily polluted lake area in China (Ya-Er Lake) are presented. The vertical distribution pattern of total PCDD/Fs in soil cores reveals that the maximum concentration was in the layer ...
journal_title：Ecotoxicology and environmental safety
pub_type： 杂志文章
doi：10.1006/eesa.2002.2202
更新日期：2002-09-01 00:00:00
abstract：:After a long-term toxicity study on Bisphenol A (BPA), the European Union and U.S food and drug administration updating the rules regarding the usage of BPA by extending the prohibition of BPA to include in the production of papers, on February 2018. Therefore, it is essential to establish the trace level BPA detector...
journal_title：Ecotoxicology and environmental safety
pub_type： 杂志文章
doi：10.1016/j.ecoenv.2018.06.045
更新日期：2018-10-01 00:00:00
abstract：:Phytotoxic effects of parthenium residues incorporation and parthenium-infested rhizospheric soil on emergence and seedling growth of winter crops (wheat and canola) and weed species (wild oat and canary grass) were examined in different pot studies. In first experiment, parthenium whole plant residues were incorporat...
journal_title：Ecotoxicology and environmental safety
pub_type： 杂志文章
doi：10.1016/j.ecoenv.2015.08.019
更新日期：2015-12-01 00:00:00
abstract：:The performance of cornstack based biofilter inoculated with a mixed culture was evaluated for gas phase MEK removal under various operating conditions. Experiments were carried out at different flow rates (0.03-0.12m3h-1) and various initial concentrations (0.2-1.2g-3). A maximum elimination capacity (EC) of 35g-3h-1...
journal_title：Ecotoxicology and environmental safety
pub_type： 杂志文章
doi：10.1016/j.ecoenv.2015.09.016
更新日期：2016-12-01 00:00:00
abstract：:Leaf vegetables have strong capabilities to take up cadmium (Cd) compared to other vegetable varieties. Until now, the differences in Cd uptake and accumulation by leaf vegetables from different families and genera and the related health risks were unknown. To remedy this, we studied 71 leaf vegetables (multiple genot...
journal_title：Ecotoxicology and environmental safety
pub_type： 杂志文章
doi：10.1016/j.ecoenv.2019.109593
更新日期：2019-11-30 00:00:00
abstract：:The concept of species sensitivity differences is important in ecotoxicology and environmental risk assessment, but testing usually focuses on lethality of toxicants. The effects on the suborganismal level are mostly ignored; therefore, the present study assessed a biomarker of genotoxicity (the alkaline comet assay) ...
journal_title：Ecotoxicology and environmental safety
pub_type： 杂志文章
doi：10.1016/j.ecoenv.2006.10.005
更新日期：2007-07-01 00:00:00
abstract：:The effects of (Rac)-metolachlor and (S)-metolachlor on the avoidance behavior, bodyweight change and in vivo enzyme activity of earthworms (Eisenia foetida) were determined and compared in this study. The effects of (Rac)-metolachlor on the enzyme activities of E. foetida and bodyweight were more significant than tho...
journal_title：Ecotoxicology and environmental safety
pub_type： 杂志文章
doi：10.1016/j.ecoenv.2010.07.035
更新日期：2010-11-01 00:00:00
abstract：:This article deals with toxicological study of cadmium (Cd) as CdCl(2) on the growth and cell morphology of Escherichia coli K-12 MG1655. The minimum inhibitory concentration of Cd was 15μM. When cadmium was added at mid-log phase, growth was completely inhibited at 0.6mM and 50% of the bacterial growth retardation wa...
journal_title：Ecotoxicology and environmental safety
pub_type： 杂志文章
doi：10.1016/j.ecoenv.2012.09.017
更新日期：2012-12-01 00:00:00
abstract：:Cadmium (Cd) easily accumulates in tobacco, which endangers public health through Cd exposure from smoking. However, its uptake, translocation, and distribution in tobacco plants during plant development or its response to biochar application are poorly understood. A pot experiment was conducted with tobacco (Yunyan 8...
journal_title：Ecotoxicology and environmental safety
pub_type： 杂志文章
doi：10.1016/j.ecoenv.2020.111295
更新日期：2021-01-01 00:00:00
abstract：:Chaff is a radiofrequency countermeasure released by military aircraft, ships, and vehicles to confuse enemy radar. Chaff consists of aluminum-coated glass fibers ranging in lengths from 0.8 to 0.75 cm and is released in packets of 0.5 to 100 million fibers. The Department of Defense has determined that use of chaff i...
journal_title：Ecotoxicology and environmental safety
pub_type： 杂志文章,评审
doi：10.1006/eesa.2002.2197
更新日期：2002-09-01 00:00:00
abstract：:The potential adverse effects of e-waste recycling activity on environment are getting increasing concern. In this work, a model alga, Pseudokirchneriella subcapitata, was employed to assess the toxic effects of the leachates of paddy soils and river sediments collected from e-waste dismantling sites. Chemical analysi...
journal_title：Ecotoxicology and environmental safety
pub_type： 杂志文章
doi：10.1016/j.ecoenv.2014.10.012
更新日期：2015-01-01 00:00:00
