Using hepatitis A and B vaccination as a paradigm for effective HIV vaccine delivery.

Abstract:

BACKGROUND:An understanding of vaccine acceptance and uptake is imperative for successful vaccination of populations that will be primary targets for vaccination after a vaccine against HIV is developed and ready for dissemination. Experiences with vaccination against vaccine-preventable hepatitis (VPH) among men who have sex with men (MSM) may offer key insights to inform future HIV vaccination strategies. The purpose of this analysis was to explore what is known currently about vaccination among MSM, using knowledge gained from vaccination against VPH, and to identify important considerations from these experiences that must be explored further as a vaccine against HIV is promoted among MSM. Because cultural and political differences make it difficult to extrapolate findings from studies in one country to another, we have focused our analyses on studies conducted in the USA. METHODS:Through a qualitative systematic review of published reports, we identified eight studies that reported correlates of VPH among MSM in the USA. RESULTS:Six major domains of variables associated with vaccination against VPH were identified, including: demographics (e.g. younger age, higher educational attainment); increased vaccine knowledge; increased access to health care; provider recommendation; behaviours (e.g. same-sex behaviour, health-promoting and disease-preventing behaviours); and psychosocial factors (e.g. openness about one's sexual orientation, reduced barriers to being vaccinated, self-efficacy). CONCLUSIONS:Further research is needed to understand vaccination behaviour among MSM and to maximise acceptance and uptake after a vaccine exists. Experiences with VPH provide a real-world model on which to base preliminary assumptions about acceptance and uptake of a vaccine against HIV.

journal_name

Sex Health

journal_title

Sexual health

authors

Rhodes SD,Yee LJ

doi

10.1071/sh06069

subject

Has Abstract

pub_date

2007-06-01 00:00:00

pages

121-7

issue

2

eissn

1448-5028

issn

1449-8987

pii

SH06069

journal_volume

4

pub_type

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