Abstract:
AIM:Authors performed a Laboratory assessment for thrombophilia risk factors in a group of patients with previous deep venous thrombosis. METHODS:123 consecutive patients were considered. The following parameters were investigated by using commercially available methods: PT, aPTT, TT, Fibrinogen, D-Dimer, Anti thrombin 3 (AT), Protein C (PC), Protein S (PS), activated C protein (APC) resistance, Lupus anticoagulant (LA), FV Leiden (G1691a mutation), Prothrombin G20210A mutation, MTHFR mutation (G677T mutation), anti Prothrombin auto-antibodies (PR) IgG and IgM, anti Beta 2 glycoprotein 1 (B2GP1) auto-antibodies IgG and IgM, anti Cardiolipin (CL) auto-antibodies IgG and IgM, homocysteine. RESULTS:In the 123 patients considered we observed: two AT deficiency, one PC deficiencies, one PS deficiency, 60 FV Leiden mutation (six homozygous), 1 Prothrombin gene mutations (heterozygous), 71 MTHFR mutations (15 homozygous). Study of anti phospholipid auto antibodies showed 10 patients positive for LA, 9 for anti CL antibodies (6IgG and 3IgM), 10 for anti B2GP1 antibody (5 IgG and 5IgM), 3 for anti PR antibody (IgG). Thirty nine patients showed hyper homocysteinemia. CONCLUSION:In our study only 19 patients were free of demonstrable thrombophilia risk factor. In 51 subjects a single risk factor was identified and in 53 multiple (from 2 to 5) risk factors were identified. In our opinion a Laboratory assessment of thrombophilia risk factors after a previous episode of deep venous thrombosis is a diagnostic tool of great importance. As a matter of fact, in our experience, by using a standard analytical panel, it was possible to highlight one or more risk factors in about 85% of the patients considered.
journal_name
Minerva Medjournal_title
Minerva medicaauthors
Gessoni G,Valverde S,Canistro R,Trabuio E,Antico F,Manoni Fsubject
Has Abstractpub_date
2007-04-01 00:00:00pages
89-93issue
2eissn
0026-4806issn
1827-1669journal_volume
98pub_type
杂志文章相关文献
MINERVA MEDICA文献大全abstract::A group of heart patients and another group of healthy subjects have been studied and their systolic intervals (PEP-LVET - PEP/LVET ratio and the telediastolic index) evaluated using the mechanocardiographic system. In both long-standing and recent heart patients, the parameters studied showed significant deviations f...
journal_title:Minerva medica
pub_type: 杂志文章
doi:
更新日期:1982-09-15 00:00:00
abstract:AIM:The endometrial-proliferation related diseases leads to endometrial hyperplasia, i.e., endometriosis. Endometrial progenitor and stem cells play key roles in the beginning of endometrial proliferative disorders. The purpose of this study was the isolation of stem cells in the endometriosis lesion as well as the eva...
journal_title:Minerva medica
pub_type: 杂志文章
doi:
更新日期:2015-04-01 00:00:00
abstract::The first part of the paper examines the reasons for involving the patient's family in suggestion and autogenous therapy, giving details of the advantages and limitations of this involvement and listing the pathologies in which it is employed. Finally, the use of autogenous techniques as an aid in the diagnosis of the...
journal_title:Minerva medica
pub_type: 杂志文章
doi:
更新日期:1990-03-01 00:00:00
abstract::15 male heroin addicts, 19-26 yr, were given 20 hospital treatments for detoxifying. Therapeutic program was based on GABAergic drugs (1-glutamine, sodium valproate, pyridoxine), low doses psychodrugs and acupuncture, added from the 3rd day. A full avoidance of the withdrawal syndrome was reached in 15 out of 18 Ss so...
journal_title:Minerva medica
pub_type: 杂志文章
doi:
更新日期:1982-03-31 00:00:00
abstract::A randomized and double blind experiment has been made over 50 patients and 25 checks, by giving a dosage of 3 Fosfolip (calcium salt of phosphorylcholine chlorid with pantethine) capsules a day. The analysis results has been reported in the work. In none case the product had secondary no desired effects; while therap...
journal_title:Minerva medica
pub_type: 临床试验,杂志文章,随机对照试验
doi:
更新日期:1983-04-07 00:00:00
abstract::Primary CVT alterations and arrhythmias, occurring one hour after embolization were detected in several experiments about focal cerebral ischaemia in rabbits. 62 animals were fed on a standard diet and 15 on an atherogenic diet. Primary CVT alterations and arrhythmias occurred in 4 rabbits fed on a standard diet and i...
journal_title:Minerva medica
pub_type: 杂志文章
doi:
更新日期:1992-03-01 00:00:00
abstract::Methergoline was administered for 5 consecutive days starting on the morning after delivery in the block of lactation in 30 patients. The efficacy of the drug was evaluated in terms of milk production, and mammary congestion and pain. The results obtained and the absence of side-effects showed that the drugs was very ...
journal_title:Minerva medica
pub_type: 杂志文章
doi:
更新日期:1979-11-10 00:00:00
abstract::The intravenous arteriography, both in traditional radiology or tomography and in computed tomography (angio-TC) requires the administration of large quantities of contrast medium and the application of intense doses of radiation to a patient. The method of Schad is based on a suitable technique of injection and on th...
journal_title:Minerva medica
pub_type: 杂志文章
doi:
更新日期:1984-07-14 00:00:00
abstract::The behaviour of the partial tensions of respiratory gases and the main parameters of acid base balance in hypoxaemic and eucapnic chronic bronchopneumopathics undergoing oxygen therapy has been assessed. The patiests were subdivided into two groups, the first consisting of subjects undergoing oxygen therapy alone, th...
journal_title:Minerva medica
pub_type: 杂志文章
doi:
更新日期:1976-09-22 00:00:00
abstract::Description of a clinical case diagnosed in the first hours of life in apparently well newborn. Diagnostic suspicion by palpation and transillumination. Absence of any subjective sign. Inspective symptom the light scrotal swelling. The neonate received an immediate surgical exploration with subsequent orchiectomy. ...
journal_title:Minerva medica
pub_type: 杂志文章
doi:
更新日期:1992-12-01 00:00:00
abstract::The authors, describe a specimen of subjects from Majano, Friuli, one of the communes that were largely struck by earthquake in 1976 and therefore by its social and cultural consequences which still play an important role in the life of those people. The specimen refers to those patients who spontaneously reported abo...
journal_title:Minerva medica
pub_type: 杂志文章
doi:
更新日期:1983-04-21 00:00:00
abstract::Urinary infections often complicate the clinical course of hospitalised patients especially those with immunological diseases or under antibiotic treatment for other infectious pathologies. Urethral catheterisation is also a well known cause of such infections. The problem of urinary infections was examined in a gener...
journal_title:Minerva medica
pub_type: 杂志文章
doi:
更新日期:1986-07-14 00:00:00
abstract::Patients with acute lymphoblastic leukemia (ALL) are characterized by an unfavorable outcome in the majority of adult cases. Several clinical trials have confirmed the usefulness of a pediatric-type therapy applied to adult patients. Adults present with higher risk features at diagnosis that predispose them to chemoth...
journal_title:Minerva medica
pub_type: 杂志文章,评审
doi:10.23736/S0026-4806.20.07031-7
更新日期:2020-10-01 00:00:00
abstract::A total of 237 patients with AIDS have been observed in the infectious Disease Division of the United Hospitals of Bergamo during the past six years. Five patients (4.21%), suffering from TB and PCP, revealed PNX which was characterised by being bilateral and recurrent; it was a concomitant cause of death in 2 patient...
journal_title:Minerva medica
pub_type: 杂志文章
doi:
更新日期:1992-05-01 00:00:00
abstract:BACKGROUND:Several studies demonstrate that the adherence to asthma guidelines (GL) is poor, but only a few of them were performed in community pharmacies. Thus, we decided to study this phenomenon by administering a questionnaire (Q) in two pharmacies. METHODS:A Q was developed and administered to 138 patients-custom...
journal_title:Minerva medica
pub_type: 杂志文章,多中心研究
doi:
更新日期:2003-02-01 00:00:00
abstract::A 48-year-old female with a history of accentuated dyspnea, pleural thickening in anteromedial portion with left patchy parenchymal shadowing invading adjoining parasternal structure of the rib cage, presented 13 months later marked superclavicular, anterior mediastinic and parahilar left lymphadenopathy. Open surgica...
journal_title:Minerva medica
pub_type: 杂志文章,评审
doi:
更新日期:1996-05-01 00:00:00
abstract::We studied 335 subjects, all drug addicts for the presence of the following serological markers: HIV1 antibody, HBsAg, HBsAb, HBcAb totals. We conclude that subjects HIV1 positive (n. 149) present HBsAb in a significantly lower number (p greater than 0.001) than HIV1 negative subjects (n. 95). The presence of HBcAb is...
journal_title:Minerva medica
pub_type: 杂志文章
doi:
更新日期:1991-11-01 00:00:00
abstract::Five patients with pure mitral stenosis and atrial fibrillation were studied with cardiac catheterization in the usual fashion before and after administration of 2.5 mg. of propranolol. At the end the selective left ventricular angiocardiography was performed. The following parameters were calculated: heart rate, mean...
journal_title:Minerva medica
pub_type: 杂志文章
doi:
更新日期:1980-10-31 00:00:00
abstract:BACKGROUND:In hospitalized medical patients, the venous thromboembolism (VTE) risk is notable. Nevertheless, the available assessment model (TPF) is generally underused. In this work, we propose an ex novo risk assessment model based on the elaboration of the clinical data exhibited by the VET patients. Differently fro...
journal_title:Minerva medica
pub_type: 杂志文章
doi:10.23736/S0026-4806.18.05689-6
更新日期:2018-12-01 00:00:00
abstract:BACKGROUND:The synthetic mucolytic neltene-xine is an amide derivative of ambroxol and thiophencarboxylic acid. The aim of this open, randomised, controlled study versus sobrerol was to evaluate the efficacy and tolerability of neltenexine (oral granules in sachets) as compared with sobrerol (oral granules in sachets),...
journal_title:Minerva medica
pub_type: 临床试验,杂志文章,随机对照试验
doi:
更新日期:2001-08-01 00:00:00
abstract::The many aspects of heart electrical activity in hypertrophic cardiomyopathy have recently been described in numerous occasions. A vectorcardiographic study was made of two sisters with an echocardiographic diagnosis of hypertrophy of the free wall of the left ventricle. Both the ECG and the VCG shown evidence of pseu...
journal_title:Minerva medica
pub_type: 杂志文章
doi:
更新日期:1984-10-27 00:00:00
abstract::Daytime office blood pressure measurements (OBPM), still recommended and utilized today for diagnosis and management of hypertension and categorization of cardiovascular disease (CVD) risk, fail to reveal clinically important features of the mostly predictable BP 24 h pattern and leads to a large proportion of individ...
journal_title:Minerva medica
pub_type: 杂志文章,评审
doi:10.23736/S0026-4806.20.06834-2
更新日期:2020-12-01 00:00:00
abstract::12 patients with normal QRS either in basal condition or during atrial pacing, undergone on single premature atrial stimulation, showed several types of intraventricular aberrancies. These have been revalued with atrial premature stimulation introduced over a progressively increasing frequency of fixed atrial stimulat...
journal_title:Minerva medica
pub_type: 杂志文章
doi:
更新日期:1978-03-24 00:00:00
abstract::Insulin resistance (IR) has profound, negative effects on the function of arteries and arterioles throughout the body and leads to arterial hypertension and vascular occlusive diseases such as heart attacks and strokes. IR affects arteries and arterioles at both the endothelium and smooth muscle levels. One major, und...
journal_title:Minerva medica
pub_type: 杂志文章,评审
doi:
更新日期:2005-08-01 00:00:00
abstract::Evaluation of lymph node involvement in carcinoma of the prostate is an essential step in staging when radical management is still possible. For this purpose, lymphography, lymphoscintigraphy, thin-needle transcutaneous lymph node biopsy, and pelvic lymphadenectomy have been variously combined since 1978 in 20 new cas...
journal_title:Minerva medica
pub_type: 杂志文章,评审
doi:
更新日期:1981-04-02 00:00:00
abstract::The study reports the results of a study of a random sample of 40 patients with medial fractures of the collum femoris in whom the caput femoris was substituted by Thompson's cemented prosthesis, taken from a series of 189 operations performed between 1981 and 1987. In conclusion, Thompson's prosthesis is demonstrated...
journal_title:Minerva medica
pub_type: 杂志文章
doi:
更新日期:1990-07-01 00:00:00
abstract::Correction of incontinence as the sequel of a pull-through operation for anorectal atresia, leaving aside cases due to a mistake of the surgical technique, is based on the construction of a new sphincter. This can be done in several ways, using striped, pedicled, denervated, free, or, more recently, smooth muscle. The...
journal_title:Minerva medica
pub_type: 杂志文章
doi:
更新日期:1982-10-13 00:00:00
abstract::A long-surviving clinical case of suspected Morquio's syndrome is described. The locomotorium (vertebral dwarfism, hyphoscoliosis, but no hypoplasia of the odontoid process of the epistropheus, platyspondylia), cardiopulmonary (aortic insufficiency, arterial calcification, varices) visual (opaque lens on right eye, sc...
journal_title:Minerva medica
pub_type: 杂志文章
doi:
更新日期:1983-10-27 00:00:00
abstract::Stress is laid on the importance in digestive and absorptive physiology. The methods used for the re-insertion of the duodenum in the digestive circuit in the surgical correction of servious post-Billroth II syndromes are explained. Direct duodenal reconversion by means of the transformation of gastrojejunostomy into ...
journal_title:Minerva medica
pub_type: 杂志文章
doi:
更新日期:1978-12-15 00:00:00
abstract::Loss of his social role and various other stresses result in a psychological feeling of impotence and nothingness in the aged. Physicians should make a close study of these aspects and not identify the aged with the end of finality and segregation. Adaptation to old age is determined by the years preceding it and doct...
journal_title:Minerva medica
pub_type: 杂志文章
doi:
更新日期:1978-05-26 00:00:00