Depression-free day to utility-weighted score: is it valid?

Abstract:

BACKGROUND:Cost-utility analyses using formulas to convert depression-free days (DFDs) to utility-weighted scores are increasingly common. These formulas are based on linear extrapolation of data documenting the correlation between depression symptom severity and generic health-related quality of life. OBJECTIVE:We sought to examine the validity of formulas converting DFDs to utility weights. METHODS:We undertook an observational study with data collection at baseline, 1 week and 1, 3, 6, 9, and 12 months on 77 subjects (42 inpatient, 35 outpatient) diagnosed with current major depression. Subjects were divided into treatment response categories based on changes in depression severity. Depression severity measures used were the Hamilton Rating Scale for Depression (HAM-17) and Beck Depression Inventory (BDI) and the health-related quality of life measure was the self-administered Quality of Well-Being scale (QWB-SA). DFD calculations were based on depression severity scores and converted to utility weights using available formulas. Utility-weighted data collected over the course of 1 year were used to estimate quality-adjusted life years (QALYs). RESULTS:QALYs estimated from the QWB-SA were significantly lower than those based on utility-weighted DFD calculations but the incremental QALYs were not significantly different. Using a slightly lower utility-weighted conversion factor for the BDI or a larger BDI severity range to calculate DFDs resulted in a better fit compared with the QWB-SA. CONCLUSIONS:Our results support the validity of the existing HAM-17 utility-weighted formula and suggest modifications for the BDI formula. If generic health-related quality of life measures are not available for conducting cost-utility analyses of depression interventions then the existing HAM-17 and modified BDI formulas appear to be reasonable alternatives.

journal_name

Med Care

journal_title

Medical care

authors

Pyne JM,Tripathi S,Williams DK,Fortney J

doi

10.1097/01.mlr.0000256971.81184.aa

subject

Has Abstract

pub_date

2007-04-01 00:00:00

pages

357-62

issue

4

eissn

0025-7079

issn

1537-1948

pii

00005650-200704000-00013

journal_volume

45

pub_type

杂志文章
  • Comparison of generic versus disease-specific measures of functional impairment in patients with cataract.

    abstract::The increased demand for health status measures in evaluating medical interventions has increased the importance of clarifying when to use generic versus disease-specific health status measures. The authors compared the performance of a well known generic health status measure, the Sickness Impact Profile (SIP), and a...

    journal_title:Medical care

    pub_type: 杂志文章

    doi:

    authors: Damiano AM,Steinberg EP,Cassard SD,Bass EB,Diener-West M,Legro MW,Tielsch J,Schein OD,Javitt J,Kolb M

    更新日期:1995-04-01 00:00:00

  • Effectiveness-implementation hybrid designs: combining elements of clinical effectiveness and implementation research to enhance public health impact.

    abstract:OBJECTIVES:This study proposes methods for blending design components of clinical effectiveness and implementation research. Such blending can provide benefits over pursuing these lines of research independently; for example, more rapid translational gains, more effective implementation strategies, and more useful info...

    journal_title:Medical care

    pub_type: 杂志文章

    doi:10.1097/MLR.0b013e3182408812

    authors: Curran GM,Bauer M,Mittman B,Pyne JM,Stetler C

    更新日期:2012-03-01 00:00:00

  • The future of kidney transplantation. The effect of improvements in survival rate on the shortage of donated kidneys.

    abstract::New drugs and other medical advances in organ transplantation are expected to increase the rate of retention of transplanted kidneys, or grafts, and therefore also raise patient survival rates. In particular, the immunosuppressive drug cyclosporine has been found to reduce the likelihood of rejection of a transplanted...

    journal_title:Medical care

    pub_type: 杂志文章

    doi:

    authors: Ruth RJ,Wyszewianski L,Campbell DA

    更新日期:1987-03-01 00:00:00

  • The utility of severity of illness information in assessing the quality of hospital care. The role of the clinical trajectory.

    abstract::This research explored whether differentiating patients whose severity of illness worsened, improved, or remained the same over the hospital stay is a good screen for quality of care. The hypothesis was that substandard care is more likely to occur among patients who have worsened. Severity was measured using the Comp...

    journal_title:Medical care

    pub_type: 杂志文章

    doi:10.1097/00005650-199205000-00005

    authors: Iezzoni LI,Restuccia JD,Shwartz M,Schaumburg D,Coffman GA,Kreger BE,Butterly JR,Selker HP

    更新日期:1992-05-01 00:00:00

  • Why consider patients' preferences? A discourse analysis of clinical practice guideline developers.

    abstract:BACKGROUND:Several organizations are advocating for patients' preferences to be considered in clinical practice guideline development and implementation. However, lack of agreement on the goal and meaning of this policy curtails evaluation and development of patient involvement programs. GOAL:To describe guideline dev...

    journal_title:Medical care

    pub_type: 杂志文章

    doi:10.1097/MLR.0b013e3181a81158

    authors: Boivin A,Green J,van der Meulen J,Légaré F,Nolte E

    更新日期:2009-08-01 00:00:00

  • Promoting access and reducing expected out-of-pocket prescription drug costs for vulnerable Medicare beneficiaries: a pharmacist-directed model.

    abstract:BACKGROUND:The Medicare Part D benefit is complicated and may be costly, especially for vulnerable low-income populations where lack of resources and limited English proficiency may be barriers to optimal plan selection. OBJECTIVES:To identify vulnerable Medicare beneficiaries and lower their expected annual out-of-po...

    journal_title:Medical care

    pub_type: 杂志文章

    doi:10.1097/MLR.0b013e318202a9f2

    authors: Cutler TW,Stebbins MR,Smith AR,Patel RA,Lipton HL

    更新日期:2011-04-01 00:00:00

  • Linking the US transplant registry to administrative claims data: expanding the potential of transplant research.

    abstract:OBJECTIVE:In the United States, data on transplanted and waitlisted patients collected by the Organ Procurement and Transplantation Network (OPTN) have been widely used in transplantation research. Administrative claims data, collected by health plans for reimbursement purposes, are also commonly used in health-service...

    journal_title:Medical care

    pub_type: 杂志文章

    doi:10.1097/MLR.0b013e3180326121

    authors: Gilmore AS,Helderman JH,Ricci JF,Ryskina KL,Feng S,Kang N,Legorreta AP

    更新日期:2007-06-01 00:00:00

  • Expanding the uses of AHRQ's prevention quality indicators: validity from the clinician perspective.

    abstract:BACKGROUND:The Agency for Healthcare Research and Quality's prevention quality indicators (PQIs) are used as a metric of area-level access to quality care. Recently, interest has expanded to using the measures at the level of payer or large physician groups, including public reporting or pay-for-performance programs. H...

    journal_title:Medical care

    pub_type: 杂志文章

    doi:10.1097/MLR.0b013e3182159e65

    authors: Davies S,McDonald KM,Schmidt E,Schultz E,Geppert J,Romano PS

    更新日期:2011-08-01 00:00:00

  • An Economic Analysis of the Implementation of Team-based Collaborative Care in Outpatient General Mental Health Clinics.

    abstract:BACKGROUND:Collaborative Chronic Care Models represent an evidence-based way to structure care for chronic conditions, including mental health conditions. Few studies, however, have examined the cost implications of collaborative care for mental health. OBJECTIVE:We aimed to conduct an economic analysis of implementin...

    journal_title:Medical care

    pub_type: 杂志文章

    doi:10.1097/MLR.0000000000001372

    authors: Miller CJ,Griffith KN,Stolzmann K,Kim B,Connolly SL,Bauer MS

    更新日期:2020-10-01 00:00:00

  • A New Data Resource to Examine Meals on Wheels Clients' Health Care Utilization and Costs.

    abstract:BACKGROUND:Access to social services (eg, nutrition) can impact older adults' health care utilization and health outcomes. However, data documenting the relationship between receiving services and objective measures of health care utilization remain limited. OBJECTIVES:To link Meals on Wheels (MOW) program data to Med...

    journal_title:Medical care

    pub_type: 杂志文章

    doi:10.1097/MLR.0000000000000951

    authors: Shan M,Gutman R,Dosa D,Gozalo PL,Ogarek JA,Kler S,Thomas KS

    更新日期:2019-03-01 00:00:00

  • Underutilization of antihypertensive drugs and associated hospitalization.

    abstract::The association of underutilization of drugs prescribed for the treatment of hypertension and acute-care hospital readmissions was evaluated. The data base consisted of computerized hospitalization records and computerized out-patient pharmacy records, checked by chart audit for validity. The number of days' supply of...

    journal_title:Medical care

    pub_type: 杂志文章

    doi:10.1097/00005650-198912000-00007

    authors: Maronde RF,Chan LS,Larsen FJ,Strandberg LR,Laventurier MF,Sullivan SR

    更新日期:1989-12-01 00:00:00

  • Measuring the job satisfaction of physicians in organized settings.

    abstract::The accurate measurement of physician job satisfaction in organized practice settings is important for both policy and administrative purposes. Previous efforts to measure physician job satisfaction have been unsatisfactory because of either conceptual or methodologic weaknesses. New measures of physician job satisfac...

    journal_title:Medical care

    pub_type: 杂志文章

    doi:10.1097/00005650-198401000-00005

    authors: Lichtenstein R

    更新日期:1984-01-01 00:00:00

  • Persistent Super-Utilization of Acute Care Services Among Subgroups of Veterans Experiencing Homelessness.

    abstract:BACKGROUND:Acute health care utilization often occurs among persons experiencing homelessness. However, knowing which individuals will be persistent super-utilizers of acute care is less well understood. OBJECTIVE:The objective of the study was to identify those more likely to be persistent super-utilizers of acute ca...

    journal_title:Medical care

    pub_type: 杂志文章

    doi:10.1097/MLR.0000000000000796

    authors: Szymkowiak D,Montgomery AE,Johnson EE,Manning T,O'Toole TP

    更新日期:2017-10-01 00:00:00

  • Development and validation of a model for predicting inpatient hospitalization.

    abstract:BACKGROUND:Hospitalizations are costly for health insurers and society. OBJECTIVES:To develop and validate a predictive model for acute care hospitalization from administrative claims for a population including all age groups. RESEARCH DESIGN:We constructed a retrospective cohort study using a US health plan claims d...

    journal_title:Medical care

    pub_type: 杂志文章

    doi:10.1097/MLR.0b013e3182353ceb

    authors: Lemke KW,Weiner JP,Clark JM

    更新日期:2012-02-01 00:00:00

  • Pathways to psychotropic drugs. Understanding the basis of gender differences.

    abstract::Earlier studies have established substantial gender differences in the likelihood of obtaining a psychotropic drug prescription, and a correlation, especially among women, with such family characteristics as family responsibilities, marital separation, divorce or widowhood, and the presence of family stressors such as...

    journal_title:Medical care

    pub_type: 杂志文章

    doi:10.1097/00005650-199004000-00001

    authors: Cafferata GL,Meyers SM

    更新日期:1990-04-01 00:00:00

  • The impact of a change in Medicare reimbursement policy and HEDIS measures on stage at diagnosis among Medicare HMO and fee-for-service female breast cancer patients.

    abstract:OBJECTIVE:To examine the effects of health plan enrollment [health maintenance organizations (HMO) or fee-for-service (FFS)], a change in Medicare reimbursement policy which allowed for annual rather than biennial mammograms, and Health Plan Employer Data Information Set (HEDIS) measures on stage at diagnosis among old...

    journal_title:Medical care

    pub_type: 杂志文章

    doi:10.1097/MLR.0b013e3180616c51

    authors: Habermann EB,Virnig BA,Riley GF,Baxter NN

    更新日期:2007-08-01 00:00:00

  • Nontraditional Surrogate Decision Makers for Hospitalized Older Adults.

    abstract:BACKGROUND:Without advanced preparation of legal documents, state law determines who may serve as a surrogate decision maker for patients in hospitals. OBJECTIVES:To examine the relationship characteristics associated with traditional versus nontraditional health care surrogates who are making medical decisions for pa...

    journal_title:Medical care

    pub_type: 杂志文章

    doi:10.1097/MLR.0000000000000890

    authors: Comer AR,Slaven JE,Montz A,Burke E,Inger L,Torke A

    更新日期:2018-04-01 00:00:00

  • The measurement of expenditures for outpatient physician and dental services: methodological findings from the health insurance study.

    abstract::Survey data measuring outpatient health expenditure are evaluated for item nonresponse, measurement error, and bias. Item nonresponse is high for persons whose health care is financed through the public sector, but is otherwise manageable. Estimates of mean total and out-of-pocket physician and dental expenditure from...

    journal_title:Medical care

    pub_type: 杂志文章

    doi:10.1097/00005650-197611000-00002

    authors: Marquis KH,Marquis MS,Newhouse JP

    更新日期:1976-11-01 00:00:00

  • Predicting outcome in the intensive care unit using scoring systems: is new better? A comparison of SAPS and SAPS II in a cohort of 1,393 patients. GiViTi Investigators (Gruppo Italiano per la Valutazione degli interventi in Terapia Intensiva). Simplified

    abstract:OBJECTIVES:This study sought to compare the performance of the old and new versions of the Simplified Acute Physiology Score, SAPS and SAPS II, in classifying patients according to the risk of hospital mortality. METHODS:To compare the performance of the two systems, measures of association between the scores and obse...

    journal_title:Medical care

    pub_type: 杂志文章,多中心研究

    doi:10.1097/00005650-199809000-00009

    authors: Bertolini G,D'Amico R,Apolone G,Cattaneo A,Ravizza A,Iapichino G,Brazzi L,Melotti RM

    更新日期:1998-09-01 00:00:00

  • Portal Use Among Patients With Chronic Conditions: Patient-reported Care Experiences.

    abstract:BACKGROUND:Personal health records offer patients access to view their own health information and to manage their care online through secure patient portal tools. Little is known about the patient-reported experience in using health portals to manage chronic conditions. OBJECTIVE:In a patient-centered research study, ...

    journal_title:Medical care

    pub_type: 杂志文章

    doi:10.1097/MLR.0000000000001178

    authors: Reed ME,Huang J,Millman A,Graetz I,Hsu J,Brand R,Ballard DW,Grant R

    更新日期:2019-10-01 00:00:00

  • Predictors of patients' perceived need for medication to prevent fracture.

    abstract:BACKGROUND:Adherence with medications to prevent fractures is suboptimal. Patients' perceived need for medication is an important predictor of medication-use behavior. OBJECTIVE:Estimate the associations of patients' perceived need of medication for fracture prevention with objective indicators of fracture risk, patie...

    journal_title:Medical care

    pub_type: 杂志文章

    doi:10.1097/MLR.0b013e318202915e

    authors: Schousboe JT,Davison ML,Dowd B,Thiede Call K,Johnson P,Kane RL

    更新日期:2011-03-01 00:00:00

  • Enhancing protections for human participants in clinical and health services research: a continuing process.

    abstract::The authors provide brief information about the Department of Veterans Affairs (VA) and the Veterans Health Administration, to establish an understanding of this large, multifaceted organization. They then offer an overview of the VA's Office of Research and Development, with particular emphasis on recent and ongoing ...

    journal_title:Medical care

    pub_type: 杂志文章

    doi:10.1097/01.MLR.0000023950.96307.BD

    authors: Feussner JR,Burris JF,McGlynn G,Lavori PW

    更新日期:2002-09-01 00:00:00

  • Association of physician and hospital volume with use of aspirin and reperfusion therapy in acute myocardial infarction.

    abstract:BACKGROUND:The association between volume of patients treated and quality of care has important implications for patient referral policies and approaches to quality improvement. Most studies have focused on hospital volume alone and health outcomes. OBJECTIVES:The objective of this work was to examine the association ...

    journal_title:Medical care

    pub_type: 杂志文章

    doi:10.1097/00005650-200011000-00004

    authors: Willison DJ,Soumerai SB,Palmer RH

    更新日期:2000-11-01 00:00:00

  • Improving adherence to screening follow-up among women with abnormal Pap smears: results from a large clinic-based trial of three intervention strategies.

    abstract::In a large randomized trial involving over 2,000 women with abnormal cervical cytology (pap smear), three clinic-based interventions were tested as strategies to increase return rates for screening follow-up: 1) a personalized follow-up letter and pamphlet; 2) a slide-tape program on pap smears; and 3) transportation ...

    journal_title:Medical care

    pub_type: 临床试验,杂志文章,随机对照试验

    doi:10.1097/00005650-199203000-00004

    authors: Marcus AC,Crane LA,Kaplan CP,Reading AE,Savage E,Gunning J,Bernstein G,Berek JS

    更新日期:1992-03-01 00:00:00

  • Determinants of rural hospital conversion. A model of profound organizational change.

    abstract::One widely discussed response to the severe problems faced by many rural hospitals is to convert them into organizations that provide health services other than general, acute inpatient care. This study identifies conversions that occurred nationally from 1984 to 1991. The study also empirically examines the determina...

    journal_title:Medical care

    pub_type: 杂志文章

    doi:10.1097/00005650-199601000-00003

    authors: Alexander JA,D'Aunno TA,Succi MJ

    更新日期:1996-01-01 00:00:00

  • Health care coverage and access to care: the status of Minnesota's veterans.

    abstract:OBJECTIVES:The primary objective of this study was to examine veterans' reliance on health care services provided by the Veterans Health Administration (VHA) within Minnesota and estimate the potential effect on uninsurance rates if all eligible veterans relied on VHA coverage. Secondary objectives were to compare vete...

    journal_title:Medical care

    pub_type: 杂志文章

    doi:10.1097/01.mlr.0000170403.97264.39

    authors: Jonk YC,Call KT,Cutting AH,O'Connor H,Bansiya V,Harrison K

    更新日期:2005-08-01 00:00:00

  • Five-step methodology for evaluation and adaptation of print patient health information to meet the < 5th grade readability criterion.

    abstract:BACKGROUND:In the setting of declining U.S. literacy, new policies include use of clear communication and low-literacy accessibility practices with all patients. Reliable methods for adapting health information to meet such criteria remain a pressing need. OBJECTIVES:To report method validation (study 1) and method re...

    journal_title:Medical care

    pub_type: 杂志文章

    doi:10.1097/MLR.0b013e318249d6c8

    authors: Hill-Briggs F,Schumann KP,Dike O

    更新日期:2012-04-01 00:00:00

  • Physician decision making and variation in hospital admission rates for suspected acute cardiac ischemia. A tale of two towns.

    abstract::The authors tested the "uncertainty hypothesis," which holds that variations in rates of hospitalization or surgeries across small geographic areas reflect differences in physicians' decision making when confronting uncertainty. A small-areas variation analysis of suspected acute cardiac ischemia (ACI) admissions in n...

    journal_title:Medical care

    pub_type: 杂志文章

    doi:10.1097/00005650-199411000-00002

    authors: Green LA,Becker MP

    更新日期:1994-11-01 00:00:00

  • Electronic health record-based cardiac risk assessment and identification of unmet preventive needs.

    abstract:BACKGROUND:Cardiac risk assessment may not be routinely performed. Electronic health records (EHRs) offer the potential to automate risk estimation. We compared EHR-based assessment with manual chart review to determine the accuracy of automated cardiac risk estimation and determination of candidates for antiplatelet o...

    journal_title:Medical care

    pub_type: 杂志文章

    doi:10.1097/MLR.0b013e31818dce21

    authors: Persell SD,Dunne AP,Lloyd-Jones DM,Baker DW

    更新日期:2009-04-01 00:00:00

  • Mental health service utilization by African Americans and Whites: the Baltimore Epidemiologic Catchment Area Follow-Up.

    abstract:OBJECTIVE:To compare mental health service utilization and its associated factors between African Americans and whites in the 1980s and 1990s. DESIGN:Household-based longitudinal study with baseline interviews in 1981 and follow-up interviews from 1993 to 1996. SETTING:The Baltimore Epidemiologic Catchment Area (ECA)...

    journal_title:Medical care

    pub_type: 杂志文章

    doi:10.1097/00005650-199910000-00007

    authors: Cooper-Patrick L,Gallo JJ,Powe NR,Steinwachs DM,Eaton WW,Ford DE

    更新日期:1999-10-01 00:00:00