Extended-release bupropion: an antidepressant with a broad spectrum of therapeutic activity?

abstract：INTRODUCTION:Olanzapine long-acting injection (OLAI), or olanzapine pamoate , is one of three second generation (SGA) antipsychotics now available in a long-acting formulation. OLAI is a microcrystalline salt of pamoic acid and olanzapine suspended in an aqueous solution that slowly dissociates into the separate compon...

journal_title：Expert opinion on pharmacotherapy

authors： Chue P,Chue J

更新日期：2012-08-01 00:00:00

abstract：INTRODUCTION:Treatment of complicated intra-abdominal infections (cIAIs) is becoming increasingly difficult because of the widespread emergence of multidrug-resistant organisms. AREAS COVERED:In this review, we discuss the effectiveness of several new antibiotics for the treatment of cIAIs, including new β-lactamase i...

journal_title：Expert opinion on pharmacotherapy

authors： Lin SY,Huang CH,Ko WC,Chen YH,Hsueh PR

更新日期：2016-01-01 00:00:00

abstract：IMPORTANCE OF THE FIELD:The clinical features and natural history of HIV-associated lymphomas differ greatly from those observed in the general population. The failure to improve outcomes with treatment intensification indicates the need for the introduction of new therapeutic options. AREAS COVERED IN THIS REVIEW:Thi...

journal_title：Expert opinion on pharmacotherapy

authors： Spina M,Gloghini A,Tirelli U,Carbone A

更新日期：2010-10-01 00:00:00

abstract：:The availability of antiretroviral therapy has significantly reduced the morbidity and mortality of HIV infection. In addition, improved treatment of opportunistic infections and comorbidities common to patients with HIV is further prolonging the lives of patients. Improvement in the treatment of HIV has led to a sign...

journal_title：Expert opinion on pharmacotherapy

authors： Robertson SM,Penzak SR,Pau AK

更新日期：2005-02-01 00:00:00

abstract：OBJECTIVES:In 1991, small cell lung cancer (SCLC) was reported as the first tumour type where colony stimulating factor (CSF) support was clinically effective. We reviewed 13 health services research studies that addressed CSF use as supportive care for SCLC. METHODS:Findings from American Society of Clinical Oncology...

journal_title：Expert opinion on pharmacotherapy

authors： Adams JR,Lyman GH,Djubegovic B,Feinglass J,Bennett CL

更新日期：2002-09-01 00:00:00

abstract：:Colorectal cancer is one of the most common types of cancer in both men and women. Multiple chemotherapy combinations exist; however, there is currently no strategy for individualised therapy selection prior to treatment. Genetic polymorphisms in genes involved in the metabolism, transport or targets for the commonly ...

journal_title：Expert opinion on pharmacotherapy

authors： Marsh S

更新日期：2005-12-01 00:00:00

abstract：INTRODUCTION:Peripheral artery disease (PAD) is a prevalent but underdiagnosed manifestation of atherosclerosis that has a worse prognosis than coronary artery disease. Patients with PAD are at heightened risk of both systemic cardiovascular adverse events and limb-related morbidity. There is insufficient awareness of ...

journal_title：Expert opinion on pharmacotherapy

authors： Essa H,Torella F,Lip GYH

更新日期：2020-09-01 00:00:00

abstract：INTRODUCTION:Inhaled corticosteroids (ICS) alone or in combination with an inhaled long-acting beta2-agonist (LABA) are the preferred long-term treatment for adults and adolescents with symptomatic asthma. Additional drugs include leukotriene-receptor antagonists, slow-release theophylline and the long-acting muscarini...

journal_title：Expert opinion on pharmacotherapy

authors： Thomson NC

更新日期：2017-02-01 00:00:00

abstract：:This article reviews the evidence supporting different somatic treatment strategies in the acute and maintenance treatment phases of bipolar disorder. Bipolar affective disorder is a chronic disorder with a life time incidence of 0.3 - 1.5/100 [1]. Severe affective disorder is associated with a risk of completed suici...

journal_title：Expert opinion on pharmacotherapy

authors： Watson S,Young AH

更新日期：2001-04-01 00:00:00

abstract：INTRODUCTION:Psoriasis is a chronic, inflammatory disease afflicting 2% of the US population; it results in significant morbidity. The annual healthcare costs related to psoriasis are an estimated $11.3 billion and, with an expanding biologic market, an updated costs analysis is needed. AREAS COVERED:Current treatment...

journal_title：Expert opinion on pharmacotherapy

authors： Staidle JP,Dabade TS,Feldman SR

更新日期：2011-09-01 00:00:00

abstract：:Gestational diabetes (GD) develops because pregnancy increases requirements for insulin secretion while increasing insulin resistance. Women with GD often have impaired pancreatic beta-cell compensation for insulin resistance. The nature of GD is currently contentious, with debate about its existence, diagnosis and ra...

journal_title：Expert opinion on pharmacotherapy

authors： Glueck CJ,Goldenberg N,Streicher P,Wang P

更新日期：2002-11-01 00:00:00

abstract：BACKGROUND:Pegaptanib sodium, the first aptamer therapeutic approved for use and the first antiangiogenic agent used to treat ocular neovascular disease, acts by inhibiting the 165 isoform of vascular endothelial growth factor believed primarily responsible for pathologic ocular neovascularization and vascular permeabi...

journal_title：Expert opinion on pharmacotherapy

authors： Apte RS

更新日期：2008-02-01 00:00:00

abstract：BACKGROUND:Incomplete remission and treatment resistance are common even in first-episode psychosis patients. OBJECTIVE:The aim of this review was to provide an overview of the available interventions and treatment pathways for the management of incomplete remission and treatment resistance in first-episode psychosis....

journal_title：Expert opinion on pharmacotherapy

authors： Lambert M,Naber D,Huber CG

更新日期：2008-08-01 00:00:00

abstract：BACKGROUND:Constituting approximately 30% of lymphoid malignancies, diffuse large B-cell lymphoma (DLBCL) is the most common aggressive lymphoma in adults worldwide. The clinical and biologic heterogeneity that exists in DLBCL suggests that this entity might actually be comprised of several distinct neoplasms that coul...

journal_title：Expert opinion on pharmacotherapy

authors： Escalón MP,Lossos IS

更新日期：2008-09-01 00:00:00

abstract：INTRODUCTION:The global epidemic of diabetes has led to an epidemic of diabetes complications. Diabetic neuropathy is the most common microvascular complication, of which diabetic peripheral neuropathy (DPN) and autonomic neuropathy (AN) are the most prevalent, affecting ~50% of patients. DPN results in pain with a poo...

journal_title：Expert opinion on pharmacotherapy

authors： Azmi S,Alam U,Burgess J,Malik RA

更新日期：2021-01-01 00:00:00

abstract：:One of the most significant advances of the last decade has been the development of platelet glycoprotein (GP) IIb/IIIa receptor inhibitors. A large series of randomised, controlled clinical trials of these agents have shown a significant reduction in ischaemic events, not only in acute coronary syndrome patients, but...

journal_title：Expert opinion on pharmacotherapy

authors： Anne G,Gruberg L

更新日期：2004-02-01 00:00:00

abstract：IMPORTANCE OF THE FIELD:Diabetes mellitus is the most common endocrine disease in childhood. The global incidence of diabetes emphasizes the health, social and financial magnitude of this disease and the importance of optimizing disease management and prevention. AREAS COVERED IN THIS REVIEW:This article reviews the t...

journal_title：Expert opinion on pharmacotherapy

authors： Verrotti A,Chiuri RM,Blasetti A,Mohn A,Chiarelli F

更新日期：2010-10-01 00:00:00

abstract：INTRODUCTION:Ziconotide is an N-type calcium channel antagonist to treat chronic pain that is delivered intrathecally. It is the only intrathecal, FDA-approved, non-opioid analgesic and is recommended as first-line therapy. Despite these advantages, a small therapeutic window limits ziconotide's clinical utility, with ...

journal_title：Expert opinion on pharmacotherapy

authors： Pope JE,Deer TR

更新日期：2013-05-01 00:00:00

abstract：:Autonomic dysreflexia is a potentially life-threatening hypertensive medical emergency that occurs most often in spinal cord-injured individuals with spinal lesions at or above the mid-thoracic spinal cord level. It is a condition that remains poorly recognised outside of spinal cord injury centres, which may result i...

journal_title：Expert opinion on pharmacotherapy

authors： Khastgir J,Drake MJ,Abrams P

更新日期：2007-05-01 00:00:00

abstract：:Anticoagulants are used for the prevention and treatment of venous thromboembolism and for the secondary prevention of stroke and myocardial infarction. The list of available anticoagulants includes unfractionated heparin, low molecular weight heparins, fondaparinux, warfarin and the direct thrombin inhibitors. Numero...

journal_title：Expert opinion on pharmacotherapy

authors： Hawkins D,Huston SA

更新日期：2006-06-01 00:00:00

abstract：:The prevalence of obesity has noticeably increased worldwide. The clinician is now frequently facing the challenge of managing patients with concomitant chronic obstructive pulmonary disease (COPD) or asthma and obesity. Obesity is often associated with a poorer control of these chronic respiratory diseases and the op...

journal_title：Expert opinion on pharmacotherapy

authors： Lessard A,Maltais F,Boulet LP

更新日期：2008-01-01 00:00:00

abstract：:Pain may produce metabolic changes after surgery, which may contribute to further morbidity. A variety of medicines and techniques can be used to successfully treat pain. It is postulated that improved analgesia leads to improved outcomes, although analgesics may also contribute to morbidity. This article reviews the ...

journal_title：Expert opinion on pharmacotherapy

authors： Engoren M

更新日期：2003-09-01 00:00:00

abstract：:Although effective anti-neoplastic agents, anthracyclines are limited by their well recognized and pervasive cardiotoxic effects. The incidence of late progressive cardiovascular disease in long-term survivors of cancer is established and may contribute to heart failure and death. To maximize the benefits of these dru...

journal_title：Expert opinion on pharmacotherapy

authors： Barry E,Alvarez JA,Scully RE,Miller TL,Lipshultz SE

更新日期：2007-06-01 00:00:00

abstract：INTRODUCTION:Chronic hepatitis C infection is a global disease with 160 million people infected worldwide. Until recently, therapy was characterized by long duration, suboptimal success rates and significant adverse drug reactions. The development of direct-acting antivirals initiated a dramatic change in the treatment...

journal_title：Expert opinion on pharmacotherapy

authors： Stirnimann G

更新日期：2014-12-01 00:00:00

abstract：:In > 80% of patients with autoimmune hepatitis, steroid therapy alone or in combination with azathioprine results in disease remission. Treatment response results in reversal of fibrosis and excellent long-term survival in many patients, whereas untreated patients may expect a 10-year survival of < 30%. The use of aza...

journal_title：Expert opinion on pharmacotherapy

authors： Heneghan MA,Al-Chalabi T,McFarlane IG

更新日期：2006-02-01 00:00:00

abstract：BACKGROUND:This study aimed to analyze the characteristics and outcomes of patients suffering from non-small-cell lung cancer (NSCLC) with epidermal growth factor receptor mutations (EGFRm+) receiving gefitinib who remained clinically stable following confirmation of progressive disease (PD) using Response Evaluation C...

journal_title：Expert opinion on pharmacotherapy

authors： Hosomi Y,Tanai C,Yoh K,Goto Y,Sakai H,Kato T,Kaburagi T,Nishio M,Kim YH,Inoue A,Hasegawa Y,Isobe H,Tomizawa Y,Mori Y,Minato K,Yamada K,Ohashi Y,Kunitoh H

更新日期：2018-07-01 00:00:00

abstract：INTRODUCTION:Clostridium difficile has become the most important healthcare-associated infection worldwide within the past decade. This is in part due to the emergence of a highly virulent epidemic strain of C. difficile as well as the relative ineffectiveness of current therapies at producing a sustained response. Fid...

journal_title：Expert opinion on pharmacotherapy

authors： Hostler CJ,Chen LF

更新日期：2013-08-01 00:00:00

abstract：:Osteosarcoma is the most frequent primary cancer of bone. When treated by surgery alone, it is almost invariably followed by metastatic dissemination and death. This dismal prognosis can be improved dramatically by including chemotherapy in an interdisciplinary regimen. Today, two-thirds of patients with localised ext...

journal_title：Expert opinion on pharmacotherapy

authors： Bielack SS,Machatschek JN,Flege S,Jürgens H

更新日期：2004-06-01 00:00:00

abstract：:Chronic refractory angina is a term used to describe patients who, despite optimal medical therapy, have both angina and objective evidence of ischaemia. It is estimated that 5-15% of the 12 million patients with chronic angina in the US meet the criteria for having refractory angina. This review focuses on the follow...

journal_title：Expert opinion on pharmacotherapy

authors： Yang EH,Barsness GW

更新日期：2006-02-01 00:00:00

abstract：INTRODUCTION:Aripiprazole long acting once-monthly (AOM) is approved for the treatment of schizophrenia in adults. Despite recent evidence of AOM efficacy in the acute treatment of schizophrenia, it is recommended that AOM should be started once the acute symptoms are controlled and patients are stabilized. However, th...

journal_title：Expert opinion on pharmacotherapy

authors： Amodeo G,Candiracci C,Capecci I,De Filippis S,Giuliani S,Guerani G,Tomasetti C,Villari V,Fagiolini A

更新日期：2016-11-01 00:00:00