Abstract:
STUDY DESIGN:To determine the effect of cage/spacer stiffness on the stresses in the bone graft and cage subsidence. OBJECTIVE:To investigate the effect of cage stiffness on the biomechanics of the fused segment in the lumbar region using finite element analysis. SUMMARY OF BACKGROUND DATA:There are a wide variety of cage/spacer designs available for lumbar interbody fusion surgery. These range from circular, tapered, rectangular with and without curvature, and were initially manufactured using titanium alloy. Recent advances in the medical implant industry have resulted in using medical grade polyetheretherketone (PEEK). The biomechanical advantages of using different cage material in terms of stability, subsidence, and stresses in bone graft are not fully understood. METHODS:A previously validated 3-dimensional, nonlinear finite element model of an intact L3-L5 segment was modified to simulate posterior interbody fusion spacers made of PEEK ("E" = 3.6 GPa) and titanium ("E" = 110 GPa) at the L4/5 disc with posterior instrumentation. Bone graft ("E" = 12 GPa) packed between the spacers in the intervertebral space was also simulated. The posterior lumbar interbody fusion spacer with instrumentation and graft represent a simulation of the condition present immediately after surgery. RESULTS:The peak centroidal Von Mises stresses in the graft bone increased by at least 9-fold with PEEK spacers as compared to titanium spacer. The peak centroidal Von Mises stresses in the endplates increased by at least 2.4-fold with titanium spacers over the PEEK spacers. These stresses were concentrated at places where the spacer interfaced with the endplate. The stiffness of the spacer did not affect the relative motion (stability) across the instrumented (L4/5) segment. CONCLUSIONS:Spacers less stiff than the graft will: (1) provide stability similar to titanium cages in the presence of posterior instrumentation, (2) reduce the stresses in endplates adjacent to the spacers, and (3) increase the load transfer through the graft, as evident from the increase in stresses in graft.
journal_name
Spine (Phila Pa 1976)journal_title
Spineauthors
Vadapalli S,Sairyo K,Goel VK,Robon M,Biyani A,Khandha A,Ebraheim NAdoi
10.1097/01.brs.0000250177.84168.basubject
Has Abstractpub_date
2006-12-15 00:00:00pages
E992-8issue
26eissn
0362-2436issn
1528-1159pii
00007632-200612150-00017journal_volume
31pub_type
杂志文章相关文献
SPINE文献大全abstract:STUDY DESIGN:An in vivo rat-tail model was adopted to study the structural changes of degenerated intervertebral disc after different traction protocols. OBJECTIVE:To investigate the effects of traction with different modes and magnitudes on disc with simulated degeneration. SUMMARY OF BACKGROUND DATA:Traction has be...
journal_title:Spine
pub_type: 杂志文章
doi:10.1097/BRS.0b013e3181c617f6
更新日期:2010-06-15 00:00:00
abstract:STUDY DESIGN:A biomechanical study was performed using cadaveric cervical spine specimens. OBJECTIVE:To determine the effect of cervical spine fusion on adjacent-level intradiscal pressure. SUMMARY OF BACKGROUND DATA:Clinical studies have reported that patients with spinal fusion are at greater risk of pathology and ...
journal_title:Spine
pub_type: 杂志文章
doi:10.1097/00007632-200211150-00003
更新日期:2002-11-15 00:00:00
abstract:STUDY DESIGN:Subacute compression of the spinal cord was applied to rats. The animals were chronologically observed using magnetic resonance imaging for more than 8 weeks after surgery and were killed for histopathologic examination. OBJECTIVES:To investigate the correlation of changes in signal intensity on magnetic ...
journal_title:Spine
pub_type: 杂志文章
doi:10.1097/00007632-199807150-00008
更新日期:1998-07-15 00:00:00
abstract:STUDY DESIGN:Prospective observational study. OBJECTIVE:To provide a more accurate estimate of the rate of acute spinous process fractures associated with IPS surgery. SUMMARY OF BACKGROUND DATA:Biomechanical cadaveric studies have suggested adequate spinous process strength to support placement of interspinous proce...
journal_title:Spine
pub_type: 临床试验,杂志文章
doi:10.1097/BRS.0b013e318204066a
更新日期:2011-07-15 00:00:00
abstract::A dynamic servocontrolled torsion machine has been used to characterize cervical injury due to pure rotation of the head. Resultant force moment, torque, and applied rotation have been measured. Torque applied to the base of the skull resulted in injury to the atlantoaxial joint. No evidence of lower cervical injury w...
journal_title:Spine
pub_type: 杂志文章
doi:10.1097/00007632-199108000-00002
更新日期:1991-08-01 00:00:00
abstract:STUDY DESIGN:An established rabbit posterolateral lumbar fusion model was used to evaluate the ability of osteogenic protein-1 to overcome the inhibitory effect of nicotine. OBJECTIVE:To determine whether osteogenic protein-1 should be considered as a bone graft alternative for the patient who smokes. SUMMARY OF BACK...
journal_title:Spine
pub_type: 杂志文章
doi:10.1097/00007632-200108010-00004
更新日期:2001-08-01 00:00:00
abstract:STUDY DESIGN:A prospective cohort design was used to evaluate the Functional Rating Index in a multicentered setting with 139 participants. The Functional Rating Index is a self-reporting instrument consisting of 10 items, each with 5 possible responses that express graduating degrees of disability. OBJECTIVES:The goa...
journal_title:Spine
pub_type: 杂志文章,多中心研究
doi:10.1097/00007632-200101010-00015
更新日期:2001-01-01 00:00:00
abstract:STUDY DESIGN:A retrospective analysis of collected data. OBJECTIVE:Our study aims to present the morphology of cranial-cervical spinal canal in basilar invagination (BI) patients. SUMMARY OF BACKGROUND DATA:BI is characterized by protrusion of the odontoid process into the foramen magnum (C0), leading to compression ...
journal_title:Spine
pub_type: 杂志文章
doi:10.1097/BRS.0000000000002706
更新日期:2018-11-15 00:00:00
abstract:STUDY DESIGN:Acute respiratory compromise is occasionally observed in a subgroup of patients with upper spinal injuries involving the C2 vertebrae. A retrospective review was performed to identify fracture types and risk factors for early respiratory deterioration following injury to the upper cervical spine. OBJECTIV...
journal_title:Spine
pub_type: 杂志文章
doi:10.1097/00007632-200102150-00004
更新日期:2001-02-15 00:00:00
abstract:STUDY DESIGN:A retrospective study. OBJECTIVE:To investigate the treatment of odontoid fractures combined with lower cervical spinal injury. SUMMARY OF BACKGROUND DATA:Odontoid fractures combined with a lower cervical spinal injury are rarely reported in the literature and their incidence and characteristics are not ...
journal_title:Spine
pub_type: 杂志文章
doi:10.1097/BRS.0b013e31817c4ecf
更新日期:2008-09-01 00:00:00
abstract:STUDY DESIGN:Case series. OBJECTIVE:To present the difficulty of diagnosing the origin of lower leg pain in patients with lumbar spinal stenosis and hip joint arthritis. SUMMARY OF BACKGROUND DATA:Pain arising from a degenerated hip joint is sometimes localized to the lower leg. Patients with lumbar spinal disease ma...
journal_title:Spine
pub_type: 杂志文章
doi:10.1097/BRS.0b013e31825d213d
更新日期:2012-12-01 00:00:00
abstract:STUDY DESIGN:Retrospective morphometric population study. OBJECTIVE:To characterize pedicle and spinal canal morphology of the achondroplastic lower thoracic and lumbar vertebrae and to suggest dimensions for improving pedicle screw selection and placement. SUMMARY OF BACKGROUND DATA:Although morphometric population ...
journal_title:Spine
pub_type: 杂志文章
doi:10.1097/BRS.0b013e3181574286
更新日期:2007-10-15 00:00:00
abstract:STUDY DESIGN:Literature review. OBJECTIVE:To determine characteristics and trends in published spine research over a recent decade in a high impact, general orthopedic surgery journal. SUMMARY OF BACKGROUND DATA:Recent trends in published spine research in a high-impact orthopedic surgery journal are unknown. Such kn...
journal_title:Spine
pub_type: 杂志文章,评审
doi:10.1097/BRS.0000000000003189
更新日期:2020-01-15 00:00:00
abstract:STUDY DESIGN:Prospective cohort study. OBJECTIVE:To investigate whether classification of increased signal intensity (ISI) on magnetic resonance imaging (MRI) of spinal cord in patients with cervical ossification of the posterior longitudinal ligament (C-OPLL) reflects severity of myelopathy and surgical outcome. SUM...
journal_title:Spine
pub_type: 杂志文章
doi:10.1097/BRS.0000000000001717
更新日期:2017-01-15 00:00:00
abstract:STUDY DESIGN:This was a subanalysis of an international, multicenter, open-label study. OBJECTIVE:The aim of this study was to assess the efficacy and safety of denosumab in a subset of patients with giant cell tumors of bone (GCTB) of the spine including the sacrum from an international, open-label, single-arm, phase...
journal_title:Spine
pub_type: 杂志文章
doi:10.1097/BRS.0000000000003728
更新日期:2020-10-08 00:00:00
abstract:STUDY DESIGN:A retrospective, multicenter, case-controlled study. OBJECTIVE:The aim of this study was to investigate the clinical and radiographical differences between thoracic idiopathic spinal cord herniation (ISCH) and spinal arachnoid cyst (SAC). SUMMARY OF BACKGROUND DATA:ISCH and SAC are relatively rare diseas...
journal_title:Spine
pub_type: 杂志文章
doi:10.1097/BRS.0000000000002013
更新日期:2017-08-15 00:00:00
abstract::Electromyographic studies have determined that muscle imbalance and asymmetry of stretch receptors in the paraspinal muscle of patients with idiopathic scoliosis may have a large role to play in the development and production of the deformity. This project consisted of a detailed histologic and histochemical analysis ...
journal_title:Spine
pub_type: 杂志文章
doi:10.1097/00007632-198805000-00004
更新日期:1988-05-01 00:00:00
abstract:STUDY DESIGN:Case report and review of relevant literature. OBJECTIVE:To report a rare complication of esophageal perforation in cervical fracture patient with progressive ankylosing spondylitis (AS) and review of relevant literature. SUMMARY OF BACKGROUND DATA:Esophageal perforation in cervical fracture is extremely...
journal_title:Spine
pub_type: 杂志文章,评审
doi:10.1097/BRS.0000000000001885
更新日期:2016-11-15 00:00:00
abstract:STUDY DESIGN:Retrospective review and prospective validation study. OBJECTIVE:To develop a classification system of lumbar lateral listhesis that suggests different likelihoods of having radiculopathy in adult scoliosis. SUMMARY OF BACKGROUND DATA:The association of lumbar lateral listhesis with radiculopathy remains...
journal_title:Spine
pub_type: 杂志文章
doi:10.1097/BRS.0000000000002986
更新日期:2019-07-15 00:00:00
abstract:STUDY DESIGN:Retrospective cohort study. OBJECTIVE:The purpose of this investigation was to evaluate the regional variations in the use of nonoperative therapies in patients diagnosed with a lumbar intervertebral disc herniation 3 months prior to undergoing microdiscectomy surgery. SUMMARY OF BACKGROUND DATA:Regional...
journal_title:Spine
pub_type: 杂志文章
doi:10.1097/BRS.0000000000003125
更新日期:2019-11-15 00:00:00
abstract:STUDY DESIGN:A prospective study of patients whose spinal cord tumors were managed surgically with a unique posterior method of removing and replacing the posterior spinal elements using T-saw ("recapping T-saw laminoplasty"). OBJECTIVES:To examine the safety and efficacy of the recapping T-saw laminoplasty technique ...
journal_title:Spine
pub_type: 杂志文章
doi:10.1097/00007632-199907010-00015
更新日期:1999-07-01 00:00:00
abstract:STUDY DESIGN:Multicenter, randomized, patient-assessor blind, sham-controlled clinical trial. OBJECTIVE:To investigate the efficacy of acupuncture treatment with individualized setting for reduction of bothersomeness in participants with chronic low back pain (cLBP). SUMMARY OF BACKGROUND DATA:Low back pain is one of...
journal_title:Spine
pub_type: 杂志文章,多中心研究,随机对照试验
doi:10.1097/BRS.0b013e318275e601
更新日期:2013-04-01 00:00:00
abstract::Double level compression of nerve roots has been known to exist for a long time, but only in recent years the clinical significance of such conditions has been discussed. In the current study, nerve root function in double level compression was analyzed by measurements of tail muscle electromyogram, after stimulations...
journal_title:Spine
pub_type: 杂志文章
doi:10.1097/00007632-199209000-00011
更新日期:1992-09-01 00:00:00
abstract:STUDY DESIGN:Radiographic results from a prospective, randomized, multicenter trial assessing patients who underwent lumbar total disc replacement (TDR) or circumferential arthrodesis for 1-level degenerative disc disease. OBJECTIVE:To quantify the relative segmental contribution to total lumbar range of motion (ROM) ...
journal_title:Spine
pub_type: 杂志文章,多中心研究,随机对照试验
doi:10.1097/BRS.0b013e3181af2622
更新日期:2009-11-01 00:00:00
abstract:STUDY DESIGN:Prospective, longitudinal cohort study. OBJECTIVE:To examine the incidence of bone morphogenetic protein (BMP)-2 antibody formation in lumbar spine applications and to determine the clinical significance of an antibody response. SUMMARY OF BACKGROUND DATA:Immune responses can affect the safety and effica...
journal_title:Spine
pub_type: 杂志文章
doi:10.1097/BRS.0b013e3182059a8c
更新日期:2011-12-01 00:00:00
abstract::A retrospective study has been made of 264 posterior spinal fusions performed between 1972 and 1978 at the Good Samaritan Hospital in Cincinnati. Two hundred ten of the procedures were performed under hypotensive anesthesia. Blood loss and total blood replacement were related to the mean arterial pressure (MAP) during...
journal_title:Spine
pub_type: 杂志文章
doi:10.1097/00007632-198407000-00005
更新日期:1984-07-01 00:00:00
abstract::Spinal cord evoked potentials were recorded from spinous processes of the lumbar, thoracic, and cervical levels of the spinal column of normal cats in response to direct stimulation of the sciatic nerve and subcutaneous stimulation of the posterior tibial nerve. The typical primary response was altered by changes in l...
journal_title:Spine
pub_type: 杂志文章
doi:10.1097/00007632-197911000-00007
更新日期:1979-11-01 00:00:00
abstract:STUDY DESIGN:A case report is presented. OBJECTIVE:To describe a case of severe symptomatic lumbar stenosis in an adult gorilla successfully treated with decompressive surgery. SUMMARY OF BACKGROUND DATA:Although spinal degenerative disease is thought to be less common in apes than in humans, gorillas and bonobos are...
journal_title:Spine
pub_type: 杂志文章
doi:10.1097/01.brs.0000112075.03500.5b
更新日期:2004-03-01 00:00:00
abstract::A patient with idiopathic hypertrophic spinal pachymeningitis (HSP) with predominant involvement of the cervical and thoracic dura is reported. Serial magnetic resonance (MR) images detected isolated thickening and ridges of the dura mater. There has been no report describing the serial changes of MR images in idiopat...
journal_title:Spine
pub_type: 杂志文章,评审
doi:10.1097/00007632-199403000-00021
更新日期:1994-03-01 00:00:00
abstract::Lumbar intervertebral joints were subjected to compressive and shear forces calculated to simulate walking with a heavy pack on the back. The joints with articular tropism were found to rotate toward the side of the more oblique facet. The mechanics relating the orientation of the articular facets with joint forces an...
journal_title:Spine
pub_type: 杂志文章
doi:10.1097/00007632-198003000-00011
更新日期:1980-03-01 00:00:00