Abstract:
:In this study, feral leaping mullet (Liza saliens) liver microsomal 7-ethoxyresorufin O-deethylase (EROD), and cytosolic glutathione S-transferases (GSTs) activities were investigated using 7-ethoxyresorufin, 1-chloro-2,4-dinitrobenzene (CDNB), and ethacrynic acid (EA) as substrates, respectively. The average EROD activity was found as 1139+/-175 pmol resorufin/min/mg protein. The average GST activities towards CDNB and EA were found as 1364+/-41 and 140+/-19 nmol/min/mg protein, respectively. We have, then, investigated the in vitro effects of some metals and detergents on CYP1A and GST activities in leaping mullet liver. Leaping mullet liver microsomal EROD activity was significantly inhibited by Hg (0.1 mM), Ni (0.1 mM), Cd (0.1 mM), Cu (0.1 mM), Zn (0.1 mM), Sb (0.1 mM), Fe2+ (1 mM), Co (1 mM), Al (1 mM), and Fe3+ (1 mM), with the percent inhibition of 80, 80, 77, 75, 70, 69, 56, 53, 46, and 44, respectively. Similarly, conjugation of CDNB catalyzed by GST was inhibited significantly to lesser extend by Hg (0.1mM), Sb (0.1 mM), Cd (0.1 mM), Cu (0.1 mM), Zn (0.1 mM), Fe3+ (1 mM), Co (1 mM), and Fe2+ (1 mM), with the percent inhibition of 70, 69, 65, 61, 54, 51, 47, and 43, respectively. The degrees of inhibition observed on GST catalyzed EA conjugation by Hg (0.1 mM), Cd (0.1 mM), Sb (0.1 mM), Cu (0.1 mM), and Zn (0.1 mM) were 86, 78, 69, 51, and 42, respectively. In addition to metals, the effect of various detergents on leaping mullet liver EROD, GST-CDNB, and GST-EA activities were studied. It was found that ionic detergents strongly inhibited the EROD activity, whereas much less inhibitions were observed with GST catalyzed activities. Therefore, the CYP1A inhibition potencies of metals and detergents suggest that their contribution to the overall CYP1A induction in polycyclic aromatic hydrocarbons contaminated environmental samples has to be taken into account for better interpretation of environmental studies.
journal_name
Ecotoxicol Environ Safjournal_title
Ecotoxicology and environmental safetyauthors
Sen A,Semiz Adoi
10.1016/j.ecoenv.2006.08.007subject
Has Abstractpub_date
2007-11-01 00:00:00pages
405-11issue
3eissn
0147-6513issn
1090-2414pii
S0147-6513(06)00178-3journal_volume
68pub_type
杂志文章abstract::Studies were made of heavy metal accumulation in aquatic macrophytes growing in streams and ponds around Wroclaw, Poland, partly affected by atmospheric pollution, effluents of chemical factories, and groundwater contaminated by slagdumps from a smelter and power station. The highest concentrations of Cd, Co, Cr, Cu, ...
journal_title:Ecotoxicology and environmental safety
pub_type: 杂志文章
doi:10.1006/eesa.1996.0106
更新日期:1996-12-01 00:00:00
abstract::Atlantic salmon smolts were exposed to three doses of the fungicide azoxystrobin for 4 days, and physiological blood parameters and transcriptional effects in liver and muscle were evaluated in search for potential negative effects. Azoxystrobin exposure mediated up-regulation of catalase, MAPK1 and IGFBP1 in liver ti...
journal_title:Ecotoxicology and environmental safety
pub_type: 杂志文章
doi:10.1016/j.ecoenv.2010.07.017
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journal_title:Ecotoxicology and environmental safety
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doi:10.1016/j.ecoenv.2018.07.080
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journal_title:Ecotoxicology and environmental safety
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doi:10.1016/s0147-6513(02)00070-2
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abstract::Actions and interactions of two abiotic parameters--temperature (18, 21, and 24 degrees C) and photoperiod (8, 12, and 16 hr/day)--on mercury bioaccumulation (HgCl2 and CH3HgCl) by a rooted macrophyte species, Elodea densa, from the sediment source were studied using experimental designs. Comparative analysis of shoot...
journal_title:Ecotoxicology and environmental safety
pub_type: 杂志文章
doi:10.1016/0147-6513(90)90053-8
更新日期:1990-10-01 00:00:00
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journal_title:Ecotoxicology and environmental safety
pub_type: 杂志文章
doi:10.1016/0147-6513(91)90011-d
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journal_title:Ecotoxicology and environmental safety
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journal_title:Ecotoxicology and environmental safety
pub_type: 杂志文章
doi:10.1016/j.ecoenv.2014.04.044
更新日期:2015-04-01 00:00:00
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journal_title:Ecotoxicology and environmental safety
pub_type: 杂志文章
doi:10.1016/0147-6513(83)90017-9
更新日期:1983-12-01 00:00:00
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journal_title:Ecotoxicology and environmental safety
pub_type: 杂志文章
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更新日期:2020-09-01 00:00:00
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journal_title:Ecotoxicology and environmental safety
pub_type: 杂志文章
doi:10.1016/0147-6513(87)90012-1
更新日期:1987-04-01 00:00:00
abstract::The effects of salinity and temperature on the toxicity of copper to 1-day and 7-day-old larvae of Hediste diversicolor were tested using factorial analysis. Mortality of larvae was influenced by salinity, temperature, and copper, but 1-day-old larvae were more susceptible than the 7-day-old larvae. Resistance to copp...
journal_title:Ecotoxicology and environmental safety
pub_type: 杂志文章
doi:10.1016/0147-6513(90)90075-g
更新日期:1990-02-01 00:00:00
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journal_title:Ecotoxicology and environmental safety
pub_type: 杂志文章
doi:10.1016/j.ecoenv.2017.11.051
更新日期:2018-02-01 00:00:00
abstract::The kinetics of uptake and metabolism of benzo[a]pyrene (BaP) were studied in various tissues of a marine fish, the sea bass (Dicentrarchus labrax), after intragastric administration of pellets containing a 14C-labeled compound. Only 25% of injected radioactivity was detected and it was found only in intestine, gallbl...
journal_title:Ecotoxicology and environmental safety
pub_type: 杂志文章
doi:10.1016/0147-6513(92)90062-8
更新日期:1992-04-01 00:00:00
abstract::D151 resin preloaded with Fe3+ [denoted as R-Fe3+] was to investigate R-Fe3+ as an adsorbent for glyphosate from water in the presence high concentration of salt. The adsorption mechanism revealed the coordination of Fe3+ inside R-Fe3+ with O atoms of P-O and N atoms in glyphosate molecule. The adsorption capacity of ...
journal_title:Ecotoxicology and environmental safety
pub_type: 杂志文章
doi:10.1016/j.ecoenv.2019.110140
更新日期:2020-03-01 00:00:00
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journal_title:Ecotoxicology and environmental safety
pub_type: 杂志文章
doi:10.1006/eesa.1996.0076
更新日期:1996-10-01 00:00:00
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journal_title:Ecotoxicology and environmental safety
pub_type: 杂志文章
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journal_title:Ecotoxicology and environmental safety
pub_type: 杂志文章
doi:10.1006/eesa.1996.0034
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journal_title:Ecotoxicology and environmental safety
pub_type: 杂志文章
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journal_title:Ecotoxicology and environmental safety
pub_type: 杂志文章
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journal_title:Ecotoxicology and environmental safety
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abstract::The biological activity of essential oil extracted from the leaves of Polygonum hydropiper and a compound, confertifolin, isolated from this plant was bioassayed against larva of mosquitoes, Anopheles stephensi and Culex quinquefasciatus. The essential oil showed the LC50 values of 189 and 243ppm; 217 and 242ppm, conf...
journal_title:Ecotoxicology and environmental safety
pub_type: 杂志文章
doi:10.1016/j.ecoenv.2013.06.028
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abstract::The effects of the insecticidal Cry1Ab protein from Bacillus thuringiensis (Bt) on the nematode, Caenorhabditis elegans, were studied with soil from experimental fields cultivated with transgenic Bt corn (MON810) and with trypsinized Cry1Ab protein expressed in Escherichia coli. The content of Cry1Ab protein was above...
journal_title:Ecotoxicology and environmental safety
pub_type: 杂志文章
doi:10.1016/j.ecoenv.2007.10.017
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abstract::Regional haze episode has already caused overwhelming public concern. Unraveling the health effects of the representative composition mixtures of atmospheric fine particulate matters (PM2.5) becomes a top priority. In this study, a novel computational solution integrating chemical-induced genomic residual effect predi...
journal_title:Ecotoxicology and environmental safety
pub_type: 杂志文章
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journal_title:Ecotoxicology and environmental safety
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abstract::Recent studies have documented that microcystins (MCs) have potential toxic effects on growth and reproduction in fish. However, no systematic data exist on whether MCs cause gonadal development retardation through disrupting the growth hormone/insulin-like growth factors (GH/IGFs) system. To this end, zebrafish hatch...
journal_title:Ecotoxicology and environmental safety
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abstract::Polycyclic aromatic hydrocarbons (PAHs) are known for their carcinogenic, teratogenic and mutagenic properties. Benzo(a)pyrene (BaP) possesses the greatest carcinogenic potential among the various PAHs. In this study, digital gene expression (DGE) was performed to investigate the digestive gland transcriptome profile ...
journal_title:Ecotoxicology and environmental safety
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abstract::Endosulfan contaminated soil has become an important risk to the environment and human health worldwide. In the present study, endosulfan tolerant bacterial strain Delftia lacustris IITISM30 and Klebsiella aerogenes IITISM42 were isolated from pesticide stressed agricultural soil and tested for plant growth promoting ...
journal_title:Ecotoxicology and environmental safety
pub_type: 杂志文章
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abstract::Concentrations of polychlorinated biphenyls (PCBs), and organochlorine pesticides (OCPs), such as dichlorodiphenyltrichloroethane (DDT) and analogs, hexachlorocyclohexanes (HCHs) and hexachlorobenzene (HCB), were determined in 8 fish species collected during October and November 2007 from the largest Iranian wetland, ...
journal_title:Ecotoxicology and environmental safety
pub_type: 杂志文章
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abstract::The effects of cadmium and zinc mixtures on tail loss of the free-living cercarial stage of the parasitic fluke Diplostomum spathaceum were investigated at concentrations ranging from 0.1 to 10,000 microg/L. Cercariae were exposed to metal mixtures of equal concentrations, metal mixtures of unequal concentrations, and...
journal_title:Ecotoxicology and environmental safety
pub_type: 杂志文章
doi:10.1016/j.ecoenv.2003.12.018
更新日期:2005-01-01 00:00:00