A pilot study of quantitative assessment of mandible advancement using pressure-flow relationship during midazolam sedation.

Abstract:

:It has been proposed that a titration of the mandibular positioner would be a promising method for predicting the outcome of nasal continuous positive airway pressure (CPAP) therapy. This study was carried out to test the hypothesis that mandible advancement could be evaluated by analysis of inspiratory flow limitation using a titration procedure. To explore its effect, we examined upper airway pressure-flow relationships using a titrated mandible positioner during midazolam sedation. Non-flow limited inspiration occurred when the mandible was advanced 7.1 +/- 1.2 mm from centric occlusion position. In the centric occlusion position (0 mm advancement), Pcrit was -1.9 +/- 2.9 cmH2O and Rua was 23.3 +/- 4.5 cmH2O L(-1) s(-1). In the eMAP position, Pcrit was -7.3 +/- 1.9 cmH2O and Rua was 27.8 +/- 3.3 cmH2O L(-1) s(-1). Essentially no CPAP was required to overcome flow limitation in eMAP position, whereas 3.7 +/- 2.2 cmH2O CPAP was required in centric occlusion position. We conclude that assessing inspiratory flow limitation using a titrated mandible positioner was effective for estimating individual-matched mandible positions.

journal_name

J Oral Rehabil

authors

Ayuse T,Hoshino Y,Inazawa T,Oi K,Schneider H,Schwartz AR

doi

10.1111/j.1365-2842.2006.01627b.x

subject

Has Abstract

pub_date

2006-11-01 00:00:00

pages

813-9

issue

11

eissn

0305-182X

issn

1365-2842

pii

JOR1627b

journal_volume

33

pub_type

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