Ultrastructural study of the temporomandibular joint after unilateral meniscectomy in Wistar rats.

Abstract:

:Meniscectomy of the temporomandibular joint (TMJ) was frequently performed until a few years ago but now is seldom employed. This procedure induces important articular modifications but the complete extent of ultrastructural changes is still unknown. Twenty-one Wistar rats were submitted to unilateral meniscectomy. Animals were randomly divided into three groups and followed for 15, 35 or 60 days. After killing both meniscectomized and contralateral TMJ specimens were sectioned sagittally and prepared for light and scanning electron microscopy studies. Normal TMJs are characterized by glenoid fossa and condylar process with distinct conjunctive layers in which regularly arranged type 1 collagen fibres predominate. Meniscectomized animals initially exhibit a different tissue covering the eroded articular surface of the condyle with the prevalence of type 3 collagen fibres but type 1 fibres predominate in the late postoperative period. Subchondral cysts are clearly visible. A complex remodelling process of the TMJ after meniscectomy is evident with important ultrastructural modifications that may correlate to unsatisfactory clinical results. The dynamic nature of this process is also observed when specimens from different postoperative periods are compared. Surgeons should always bear in mind these alterations when indicating this procedure.

journal_name

J Oral Rehabil

authors

Martini DT,De Campos Boldrini S,De Vasconcellos Fontes RB,Liberti EA

doi

10.1111/j.1365-2842.2006.01647.x

subject

Has Abstract

pub_date

2006-10-01 00:00:00

pages

722-8

issue

10

eissn

0305-182X

issn

1365-2842

pii

JOR1647

journal_volume

33

pub_type

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