Monomorphic ventricular tachycardia due to Brugada syndrome successfully treated by hydroquinidine therapy in a 3-year-old child.

Abstract:

:Mutations in the SCN5A gene can cause Brugada syndrome, a genetically inherited form of idiopathic ventricular fibrillation. We describe the case of a 3-year-old child with a structurally normal heart presenting with monomorphic ventricular tachycardia. Her electrocardiogram suggested a Brugada syndrome and the diagnosis was confirmed by the identification of a Brugada syndrome in her mother and in two other family members. Genetic study led to the identification of a c.2516T-->C SCN5A mutation. The child was treated with quinidine therapy without recurrence of arrhythmic events for a time period of 16 months.

authors

Probst V,Evain S,Gournay V,Marie A,Schott JJ,Boisseau P,LE Marec H

doi

10.1111/j.1540-8167.2005.00329.x

keywords:

subject

Has Abstract

pub_date

2006-01-01 00:00:00

pages

97-100

issue

1

eissn

1045-3873

issn

1540-8167

pii

JCE329

journal_volume

17

pub_type

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