Abstract：
OBJECTIVES:Ki67 and PCNA proteins are characteristic for cells in mitotic cycle and represent unfavourable prognostic indices. Intensity of the proteins expression directly correlates with grade of tumour differentiation. They belong to the second category of prognostic factors in breast cancer according to the College of American Pathologists. DESIGN:Present study aimed at examining the relationship between intensity of expression of proliferation-related antigens--Ki67 and PCNA in cells of ductal breast cancer of G1, G2 or G3 differentiation grade. MATERIALS AND METHODS:In paraffin sections of 60 ductal breast cancers, immunocytochemical reactions were performed to detect expression of Ki67 and PCNA. Following semiquantitative appraisal of studied preparations, appropriate statistical tests were used to document statistical relationships. RESULTS:Intensity of Ki67 expression was most pronounced in G3 group and least pronounced in G1 group (ANOVA rang Kruskal-Wallis, p=0.00001). In the case of PCNA we did not show any differences. Only in the G1 we showed a positive correlation between expression intensity of studied antigens (Spearmans rang correlation, r=0.67, p=0.024). CONCLUSIONS:The study showed that Ki67 and not PCNA correlates with morphologic features of proliferation.
journal_name
Ginekol Poljournal_title
Ginekologia polskaauthors
Surowiak P,Pudełko M,Maciejczyk A,Dziegiel P,Wojnar A,Zabel Mkeywords:
subject
Has Abstractpub_date
2005-01-01 00:00:00pages
9-14issue
1eissn
0017-0011issn
2543-6767journal_volume
76pub_type
杂志文章abstract：OBJECTIVES:The aim of the following study was to assess antisperm antibodies in sera samples of infertile men and women, as well as from prepubertal boys by means of flow cytometry. MATERIAL AND METHODS:We tested sera samples of infertile and fertile adult populations, prepubertal boys with gonadal disorders and healt...
journal_title：Ginekologia polska
pub_type： 杂志文章
doi：
更新日期：2010-08-01 00:00:00
abstract：:The paper presents the course of treatment and results of pathological changes in the uterine cervix in 41 patients who underwent cryotherapy by means of a cryotherapeutic apparatus UK-32, using liquid nitrogen as cryogenic fluid. Complete recovery in the form of typical stratified squamous epithelium was achieved in ...
journal_title：Ginekologia polska
pub_type： 杂志文章
doi：
更新日期：1989-03-01 00:00:00
abstract：OBJECTIVES:The aim of the study is to present data concerning Neugebauer-Le Fort operations performed at the Gynecologic Oncology Clinic, Polish Mother's Health Center Research Institute in Lodz between 2000-2009, including the effects of the surgeries on improving quality of life. MATERIAL AND METHODS:Our research in...
journal_title：Ginekologia polska
pub_type： 杂志文章
doi：10.17772/gp/2063
更新日期：2015-03-01 00:00:00
abstract：:32 patients with hydatid mole were subjected to serological tests to determine the concentration of chorionic gonadotropin (HCG) in the urine. The patients were divided into 2 groups, depending on the duration of the amenorrhea. Group 1 (20 cases) showed a uterus size not exceeding the volume of the 12th week of ges...
journal_title：Ginekologia polska
pub_type： 杂志文章
doi：
更新日期：1976-09-01 00:00:00
abstract：OBJECTIVES:Recent studies have demonstrated that disorders of bone metabolism, which is regulated by RANK/RANKL/OPG signaling pathway, are the cause of osteoporosis. The aim of the study was to investigate the distribution of genotypes of the RANK 575C>T and RANKL -643C>T polymorphisms and to analyze their relationship...
journal_title：Ginekologia polska
pub_type： 杂志文章
doi：10.5603/GP.2016.0014
更新日期：2016-01-01 00:00:00
abstract：:Iniencephaly is a rare malformation characterized by the triad of occipital bone defect, cervical dysraphism and fixed retroflexion of the fetal head with poor prognosis. We present a case one of the twin with iniencephaly and congenital heart defect (common atrio-ventricular canal) with normal karyotype. ...
journal_title：Ginekologia polska
pub_type： 杂志文章
doi：
更新日期：2006-06-01 00:00:00
abstract：:Authors presented successful conservative treatment early diagnosed cervical pregnancy. After this procedure abdominal hysterectomy was not necessary. ...
journal_title：Ginekologia polska
pub_type： 杂志文章
doi：
更新日期：1996-06-01 00:00:00
abstract：:The authors describe diagnostic difficulties connected with proper estimation of stromal sarcoma biological activities, which developed in uterus corpus in 18 year old girl previously treated with hormones, because of irregular painful menses. Macroscopic and microscopic investigations of postoperative specimen allowe...
journal_title：Ginekologia polska
pub_type： 杂志文章
doi：
更新日期：1998-01-01 00:00:00
abstract：OBJECTIVES:The aim was to present pregnancy complications and outcome in the group of women with subchorionic hematoma (SCH) diagnosed in the first or second trimester of pregnancy METHODS:A retrospective study was performed to compare the perinatal outcome of 41 patients with SCH (study group) with 59 women treated o...
journal_title：Ginekologia polska
pub_type： 杂志文章
doi：
更新日期：2010-12-01 00:00:00
abstract：UNLABELLED:Cervical incompetence is one of the causes of preterm delivery. Ultrasound examination of the cervix has given the evidence that cervical shortening, dilatation of internal cervical os and funneling observed long before term are the warning signs of preterm delivery. Early diagnosis and treatment may serve b...
journal_title：Ginekologia polska
pub_type： 杂志文章
doi：
更新日期：2003-10-01 00:00:00
abstract：OBJECTIVES:To establish the appropriate technique for salpingo-oophorectomy via transvaginal natural orifice transluminal endoscopic surgery (NOTES), under gasless laparoscopy. MATERIAL AND METHODS:Ten patients with clinical indication underwent gasless laparoscopic transvaginal salpingo-oophorectomy with concurrent v...
journal_title：Ginekologia polska
pub_type： 杂志文章
doi：10.5603/GP.2020.0001
更新日期：2020-01-01 00:00:00
abstract：BACKGROUND:HLHS (hypoplastic left heart syndrome) is a serious congenital heart defect. In neonates with congenital heart disease HLHS accounts for nearly 25% of neonatal deaths. The etiology of HLHS is unknown. At present we expect to have those cases diagnosed in the second trimester of pregnancy. AIM:The main aim w...
journal_title：Ginekologia polska
pub_type： 杂志文章
doi：
更新日期：2008-06-01 00:00:00
abstract：:Family history of ovarian cancer has been regarded as the most important risk factor in developing this type of tumor. Recent identification of cloning of specific tumor suppressor genes responsible for hereditary ovarian cancer syndromes, resulted in the surge of enthusiasm and optimism regarding the practical applic...
journal_title：Ginekologia polska
pub_type： 杂志文章,评审
doi：
更新日期：2003-07-01 00:00:00
abstract：:The position of intrauterine devices (IUDs) was determined by means of ultrasonography in 68 women using Combison 200 Compound Soan ultrasonography 2 to 3 days after insertion of the IUD, after the next menstruation, and during examinations after 3 to 24 months. Pain, prolonged menstruation, and spotting between mens...
journal_title：Ginekologia polska
pub_type： 杂志文章
doi：
更新日期：1984-09-01 00:00:00
abstract：DESIGN:The aim of our study was estimation of frequency of occurrence endometriosis at girls operated from different indications, research of predisposing factors and estimation of selected biophysical parameters. MATERIAL AND METHODS:Material determined 14 of patients in 13 to 21 years old of life operated on account...
journal_title：Ginekologia polska
pub_type： 杂志文章
doi：
更新日期：2001-05-01 00:00:00
abstract：:9.98% of all gynecological surgical interventions made at the Clinic in Zabrez from 1965 to 1971 were for ectopic pregnancy. 157 cases of ectopic pregnancy were chosen at random for clinical analysis. Microscopic examinations of the excised oviduct were made in order to establish the cause of tubular implantation. ...
journal_title：Ginekologia polska
pub_type： 杂志文章
doi：
更新日期：1975-06-01 00:00:00
abstract：:A case of a 30 years old pregnant woman suffering from bilateral ovary tumour was presented. When she was sixteen weeks pregnant she had both tumours enucleated using the method of laparoscopy. Diagnostic and therapeutic process have been described. Authors are convinced that laparoscopy as a method of treatment can b...
journal_title：Ginekologia polska
pub_type： 杂志文章
doi：
更新日期：2005-05-01 00:00:00
abstract：:350 patients with ovarian cancer were operated and irradiated postoperatively in the Center of Oncology in Kraków. 5-year survival with no recurrence was 41.7% (I.--77.3%, II.--44.1%, III.--7.7%). Stage, histological grade and residual volume tumor appears to be an important prognostic factors. ...
journal_title：Ginekologia polska
pub_type： 杂志文章
doi：
更新日期：1992-01-01 00:00:00
abstract：OBJECTIVES:There is no standardized treatment modality or a generally accepted guideline in cesarean scar pregnancy (CSP) treatment. The aim of this study is to retrospectively evaluate the outcomes of the different treatment modalities used in CSP treatment. MATERIAL AND METHODS:31 CSP patients retrospectively evalua...
journal_title：Ginekologia polska
pub_type： 杂志文章
doi：10.5603/GP.2019.0053
更新日期：2019-01-01 00:00:00
abstract：UNLABELLED:Chlamydia trachomatis (CT) infection during pregnancy might be the reason of an increased risk of preterm delivery and premature rupture of membranes. CT could also be responsible for the presence of intrauterine growth restriction, chorionamnionitis and post partum endometritis. It is the most common sexual...
journal_title：Ginekologia polska
pub_type： 杂志文章
doi：
更新日期：2007-10-01 00:00:00
abstract：:The purpose of the study was to compare indications for curettage directly after delivery with histologic findings. Only in 51% there was a histologic confirmation of placental or membrane tissue. Residences indications of the suspected retained placenta were wrong in 70% cases. The curetting of 75% of the patients ex...
journal_title：Ginekologia polska
pub_type： 杂志文章
doi：
更新日期：2002-12-01 00:00:00
abstract：:The role of the peritoneal fluid in the physiology of reproduction, as well as in the transportation and survival of gametes, is little recognized. Taking this into consideration, the authors have examined the occurrence of spermatozoa in the peritoneal fluid, collected from patients during diagnostic laparoscopies, f...
journal_title：Ginekologia polska
pub_type： 杂志文章
doi：
更新日期：1995-04-01 00:00:00
abstract：:The paper concerns the treatment results of 113 women with PCO-S by laparoscopic (102) and microlaparoscopic (11) ovarian electrocautery. All of them were qualified for operation on the basis of the following criteria: menstrual cycle disturbances (oligo-/amenorrhoea), anovulation, hirsutism, obesity, LH/FSH ratio > 2...
journal_title：Ginekologia polska
pub_type： 临床试验,杂志文章
doi：
更新日期：2001-08-01 00:00:00
abstract：:The hysteroscopic evaluation of uterine openings in 23 sterile women was described. The attention was paid to morphological features of obliterated uterine openings. The hysteroscopic examination of structural changes located in uterine openings seems to be a reliable method for evaluation of potency of oviducts. This...
journal_title：Ginekologia polska
pub_type： 杂志文章
doi：
更新日期：1994-07-01 00:00:00
abstract：OBJECTIVE:Clinical application of minimally invasive surgical techniques in gynecology continuous to increase steadily. Laparoscopic surgery has widely replaced open surgical technique in many routine cases. This method is obviously less traumatic and painful, requires a shorter hospital stay and recovery time. The aim...
journal_title：Ginekologia polska
pub_type： 杂志文章
doi：
更新日期：2012-02-01 00:00:00
abstract：:Legal abortions have reduced the number of miscarriages by 20%, and of abandoned children by 56%; but at the same time, can be hazardous to the mother both initially (loss of blood, punctured uterus, damaged cervix) and later (infections in the reproductive system, infertility, extrauterine pregnancy, psychological di...
journal_title：Ginekologia polska
pub_type： 杂志文章
doi：
更新日期：1979-02-01 00:00:00
abstract：OBJECTIVES:The aim of the study was to analyze the course of labor of grand multiparas (4 deliveries and more) in comparison to multiparas (2 or 3 deliveries). MATERIALS AND METHODS:A group of 400 grand multiparas were included in the study and compared with a group of 393 multiparas. All the deliveries took place in ...
journal_title：Ginekologia polska
pub_type： 杂志文章
doi：
更新日期：2006-12-01 00:00:00
abstract：:The premenstrual syndrome occurs in the second phase of period and strain, sensitivity, nervousness, anxiety, sleeplessness, headaches, sickness, swollen breasts are the typical symptoms of the syndrome. 143 high school girls have been subjected to the anonymous questionnaire. They were divided into two groups: A--tho...
journal_title：Ginekologia polska
pub_type： 杂志文章
doi：
更新日期：1993-08-01 00:00:00
abstract：:EPH-gestosis is accompanied by an extensive remodelling of the extracellular matrix of the umbilical cord arteries, vein and Wharton's jelly. For better understanding of processes proceeding in it we decided to determine proteolytic activity in acidic pH range. Presented results suggest that cathepsin D is one of the ...
journal_title：Ginekologia polska
pub_type： 杂志文章
doi：
更新日期：2000-08-01 00:00:00
abstract：:The current knowledge concerning the fibrocystic disease of the breast is presented in this work. The authors outlined the theoretical principles of the problem and the most important diagnostic methods as well as the prophylaxis and prognostic in the fibrocystic disease of the breast. ...
journal_title：Ginekologia polska
pub_type： 杂志文章,评审
doi：
更新日期：1993-01-01 00:00:00
