A longitudinal study of 100 consecutive admissions for carbon monoxide poisoning to the Royal Adelaide Hospital.

Abstract:

:A longitudinal study of one hundred consecutive admissions to the Royal Adelaide Hospital for carbon monoxide poisoning was conducted from 1986 to 1989. Twenty-five patients left hospital with persistent symptoms and signs of this poisoning. Five subsequently recovered. Twenty-four other patients, who were well when they left hospital, did not attend for a review one month after discharge. Extensive neuropsychiatric testing at this time showed 32% (24 of 76) had obvious sequelae of their exposure. Overall, the frequency of neuropsychiatric sequelae in the patients who only received oxygen at atmospheric pressure was 63% (N = 8) on discharge and 67% (N = 6) on one month follow-up. The frequency of sequelae among those who were given one hyperbaric oxygen treatment only was 46% (N = 24) on discharge and 50% (N = 20) on one month follow-up. In contrast, the frequency of sequelae in patients who had two or more hyperbaric oxygen treatments was only 13% (N = 68) on discharge (P less than 0.005) and 18% (N = 50) on follow-up (P less than 0.005). the frequency of sequelae was also significantly greater if hyperbaric oxygen was delayed (P less than 0.05). No markers of severe poisoning could be identified.

journal_name

Anaesth Intensive Care

authors

Gorman DF,Clayton D,Gilligan JE,Webb RK

doi

10.1177/0310057X9202000306

keywords:

subject

Has Abstract

pub_date

1992-08-01 00:00:00

pages

311-6

issue

3

eissn

0310-057X

issn

1448-0271

journal_volume

20

pub_type

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