Abstract：
:Liver disease secondary to hepatitis C infection is the most common indication for liver transplantation. Infection of the allograft begins at the time of transplantation. The histological progression of hepatitis C infection is greatly accelerated in liver transplant recipients when compared to the natural history in immunocompetent patients. Chronic allograft injury is apparent in >50% of HCV-infected recipients in the first postoperative year. Approximately 10% of HCV-infected recipients die or lose their allograft secondary to hepatitis C-associated allograft failure and a further 30% will have cirrhosis by the end of the fifth postoperative year. Cumulative exposure to corticosteroids is associated with increased mortality, higher levels of HCV viremia and more severe histological recurrence. In contrast to non-HCV-infected recipients, treatment for acute cellular rejection is associated with attenuated patient survival among recipients with hepatitis C. Therapy with pegylated IFN (+/- ribavirin), although less efficacious than in immunocompetent patients, should be considered in recipients with histologically apparent recurrence of hepatitis C before jaundice develops. Ribavirin is poorly tolerated in liver transplant recipients, limiting efficacy of combination therapy. Ribavirin dosing should be adjusted for renal insufficiency. Passive immunity, through anti-HCV antibody preparations, has not been efficacious to date. The role of hepatitis C new immunosuppression agents in the management of posttransplant hepatitis C infection is still evolving.
journal_name
Minerva Chirjournal_title
Minerva chirurgicaauthors
Charlton Mkeywords:
subject
Has Abstractpub_date
2003-10-01 00:00:00pages
717-24issue
5eissn
0026-4733issn
1827-1626journal_volume
58pub_type
杂志文章,评审abstract：:Among 94 cases of pulmonary metastases treated by the exeresis of one or more nodules, 28 cases produced metastasis located in the lung only. Radical metastasectomy was performed on 250. Analysis of survival, also assessed in relation to every prognostic factor reveals the efficacy of surgical therapy even in iterativ...
journal_title：Minerva chirurgica
pub_type： 杂志文章
doi：
更新日期：1989-09-30 00:00:00
abstract：:Explorative laparotomies and palliative surgery for pancreatic carcinoma have been reduced due to improved diagnostic tools, the spread of laparoscopic techniques and the growing use of external biliary drainage and endoprostheses. By comparing two successive observation periods the authors point out that, owing to th...
journal_title：Minerva chirurgica
pub_type： 杂志文章
doi：
更新日期：1993-12-01 00:00:00
abstract：:In order to evaluate the clinical utility of autologous splenic transplantation in the omental pouch, a pneumococcal challenge was performed in 3 groups of rats, after demonstration of vitality of the intraperitoneal inoculum: Group A: splenectomized rats; Group B: reimplanted rats; Group C: sham operation. No statist...
journal_title：Minerva chirurgica
pub_type： 杂志文章
doi：
更新日期：1991-08-01 00:00:00
abstract：:Attention is drawn to the fact that renal transplants are quite commonly complicated by stenosis of the arterial pedicle. The symptomatology (hypertension, oliguria, fever and gradual loss of renal function) points to the need for angiography. In about 70% of cases, surgical management in the light of the nature of th...
journal_title：Minerva chirurgica
pub_type： 杂志文章
doi：
更新日期：1979-08-15 00:00:00
abstract：:Twenty-two patients undergoing major head and neck surgery were included in a randomized trial to value the efficacy and side effects of parenteral short-term antibiotic prophylaxis of post-operative infections. Two different antibiotic regimens were compared: group A, ceftazidime i.v. (2 g) in three doses (half an ho...
journal_title：Minerva chirurgica
pub_type： 临床试验,杂志文章,随机对照试验
doi：
更新日期：1989-11-30 00:00:00
abstract：:Resection and thermal ablation procedures are frequently used for the treatment of primary and secondary liver tumors. Various tools for the virtual planning of liver resections and ablation are available and some of them are already used clinically. Resection planes and ablation volumes can be optimized for sufficien...
journal_title：Minerva chirurgica
pub_type： 杂志文章
doi：
更新日期：2011-10-01 00:00:00
abstract：:Following and exhaustive review of the literature on this topic, the paper reports the results of the treatment of 16 patients with male breast cancer. From an analysis of findings, it was observed that diagnosis is frequently delayed (mean 1 year), disease is at a locally advanced stage in the majority of patients, a...
journal_title：Minerva chirurgica
pub_type： 杂志文章
doi：
更新日期：1990-01-01 00:00:00
abstract：:We have analysed the results of surgical treatment for microcarcinoma of the thyroid (MCT). In sixteen patient clinical and follow-up data were retrospectively evaluated during a 35.1-month follow-up. Thyroid hyperfunctional state us was present in two subjects. A single nodule was detected by echotomography in 11 pat...
journal_title：Minerva chirurgica
pub_type： 杂志文章
doi：
更新日期：1997-07-01 00:00:00
abstract：:Retrospective analysis of risk-factors in 241 patients with large abdominal incisional hernia collected in a 16-year period at the Department of Surgery, University of Pavia, allows the Authors to identify the aetiological mechanism of herniation and to discuss the fundamental technical skills in wall reconstruction. ...
journal_title：Minerva chirurgica
pub_type： 杂志文章
doi：
更新日期：1992-02-01 00:00:00
abstract：:The authors outline the stages of abdominoperineal surgery due to rectal cancer to achieve the reconstruction of perineal-stomic continence. The operation is simple to perform, without particular vascular risks and sepsis; it does not necessitate temporary abdominal colostomy and, lastly, does not oblige postoperative...
journal_title：Minerva chirurgica
pub_type： 杂志文章
doi：
更新日期：1993-06-30 00:00:00
abstract：:The Authors examine retrospectively all the cases of obstruction of the small bowel operated at the surgical department of the Verbania Hospital in the last twenty years. The records of 341 cases, 1.4% of the total amount of the surgical operations carried out in the same space of time, were retrospectively reviewed. ...
journal_title：Minerva chirurgica
pub_type： 杂志文章
doi：
更新日期：1992-12-01 00:00:00
abstract：:Emergency surgery is required for performed colonic diverticulitis. Surgical indications are not uniform in literature. In the experience of the authors the operations have been performed in the case of peritonitis subsequent to the perforation or in the case of failure of the conservative treatment. Twenty-four patie...
journal_title：Minerva chirurgica
pub_type： 杂志文章
doi：
更新日期：1994-07-01 00:00:00
abstract：BACKGROUND:Diastasis Recti Abdominis DRA is defined as an abnormally wide distance separates the two rectus muscles. Thinning and widening of the linea alba is an important risk factor for development midline hernia. In patient with DRA there is an increase rate of hernia recurrence. METHODS:We perform a retrospective...
journal_title：Minerva chirurgica
pub_type： 杂志文章
doi：10.23736/S0026-4733.20.08404-7
更新日期：2020-08-06 00:00:00
abstract：:Mucocele of the appendix is a rare lesion (only 0;2-0.3% of all appendicectomies). It is characterized by distension of the lumen within mucus. Mucoceles are often asymptomatic and are discovered as an incidental finding either at surgery or during barium edema. There have been reports of other tumors associated with ...
journal_title：Minerva chirurgica
pub_type： 杂志文章
doi：
更新日期：1995-12-01 00:00:00
abstract：:Continence depends not only on correct muscular function but also on the integrity of the suspensory structures of the anal canal, the latter being the subject of this study performed on embryological and adult specimens. The role of the perineal body as an insertion tendon common to all the striated muscles (pubo-coc...
journal_title：Minerva chirurgica
pub_type： 杂志文章,评审
doi：
更新日期：1989-06-30 00:00:00
abstract：:Despite many guidelines issued by national and professional societies, a detailed literature survey between the late 1940s and 2010 clearly demonstrates that several aspects of pneumothorax pathogenesis and treatment still remain controversial. Related to pathogenesis of primary pneumothorax, the current manuscript hi...
journal_title：Minerva chirurgica
pub_type： 杂志文章,评审
doi：
更新日期：2011-08-01 00:00:00
abstract：:Nine years experience of anorectal surgery for Crohn-related lesion have been analysed. The series regards only 14 cases with pathology including ragade, abscesses and anocutaneous and retrovaginal fistulas. Treatment was as conservative as possible except for cases in which fistulizations led to sepsis as a result of...
journal_title：Minerva chirurgica
pub_type： 杂志文章
doi：
更新日期：1990-06-30 00:00:00
abstract：BACKGROUND:There are several therapeutic proposals for idiopathic varicocele treatment, but all of them present a certain number of relapses. The technique proposed consists, through an inguinal approach, in a systematic ligation and section of all veins potentially responsible of a venous reflux. METHODS:During a per...
journal_title：Minerva chirurgica
pub_type： 杂志文章
doi：
更新日期：1999-05-01 00:00:00
abstract：BACKGROUND:Meconium ileus (MI) is a form of neonatal intestinal obstruction due to an abnormal thickened meconium within the terminal ileum. The aim of this retrospective paper is to review our experience with neonates affected from MI treated at our institute over a twenty year period. METHODS:This report deals with ...
journal_title：Minerva chirurgica
pub_type： 杂志文章
doi：
更新日期：1999-12-01 00:00:00
abstract：:A case of aneurysm of the hepatic artery associated with aneurysm of the abdominal artery in fissuration is discussed. The indications, possibilities and limits of exclusion or removal of the aneurysm without reconstructing the main artery axis in the treatment of cases involving the hepatic artery are examined in the...
journal_title：Minerva chirurgica
pub_type： 杂志文章
doi：
更新日期：1978-01-15 00:00:00
abstract：:Four cases of sarcoma of the small intestine (2 leiomyosarcoma, 1 fibrosarcoma, and 1 Hodgkin's disease) are described. In each case, diagnosis was the outcome of surgery: emergency operation for acute abdomen in three cases (2 mechanical ileus, 1 perforation); exploratory laparotomy for recurrent haemorrhage followin...
journal_title：Minerva chirurgica
pub_type： 杂志文章
doi：
更新日期：1977-03-31 00:00:00
abstract：:Of 220 patients operated for gastric cancer, 74 with subtotal gastrectomy and 145 with total gastrectomy (60 with lymphadenectomy), the results and indications for total gastrectomy extended with lymphadenectomy are analysed. The importance of lymph node emptying in relation to the possibility of breakdown of the lymp...
journal_title：Minerva chirurgica
pub_type： 杂志文章
doi：
更新日期：1990-05-15 00:00:00
abstract：AIM:Patients undergoing excision for breast lumps prefer general anesthesia or local anesthesia plus sedation, because of the fear of pain for local anesthesia alone. The aim of this study is to show the efficacy of an eutectic mixture of local anesthetic lignocaine and prilocaine (EMLA®) in these patients. METHODS:Th...
journal_title：Minerva chirurgica
pub_type： 杂志文章,随机对照试验
doi：
更新日期：2012-04-01 00:00:00
abstract：INTRODUCTION:Bronchogenic carcinomas involving the carina or the tracheo-bronchial angle represents a challenging surgical procedure because of difficult surgical techniques and complex ventilation procedures. Even though surgical outcomes for this type of procedure has improved over time, the need for surgical managem...
journal_title：Minerva chirurgica
pub_type： 杂志文章,meta分析
doi：10.23736/S0026-4733.17.07382-5
更新日期：2018-10-01 00:00:00
abstract：:Plication of the long saphena at the sapheno-femoral junction (SFJ) is an alternative to flush ligation and stripping. This technique abolishes reflux at the SFJ without altering the vein which may be used for arterial surgery or coronary grafting. The selection of the candidate for plication is done with ambulatory v...
journal_title：Minerva chirurgica
pub_type： 杂志文章
doi：
更新日期：1991-10-31 00:00:00
abstract：AIM:Postoperative air leaks and in particular persistent air leaks (>5 days) after pulmonary resection still represent a common complication and the first cause of hospital stay delay. Aim of this experimental trial was to investigate the efficacy of the use of bovine pericardium strips (in terms of reduction of postop...
journal_title：Minerva chirurgica
pub_type： 临床试验,杂志文章
doi：
更新日期：2012-02-01 00:00:00
abstract：:The surgical approach to acute cholecystitis has changed through the years. It was extended to all ages. The authors report their 10-year experience with 562 cases of cholecystitis. The mortality rate was 1.5% the morbidity rate was 7.6% The authors propose early surgery (within 72 hours of diagnosis) in the majority ...
journal_title：Minerva chirurgica
pub_type： 杂志文章
doi：
更新日期：1997-06-01 00:00:00
abstract：:Carcinoma of the gastric stump in patients who have undergone resection for duodenal and gastric ulcer represents a rare event which poses considerable diagnostic and therapeutic problems. 7 personal cases are examined, particular attention being paid to the utility of endoscopy, together with sampling for cytological...
journal_title：Minerva chirurgica
pub_type： 杂志文章
doi：
更新日期：1978-09-30 00:00:00
abstract：AIM:Despite improvement in the operative technique and graft and suture material, femoral anastomotic aneurysms (FAAs) represent a continuing problem for patients undergoing lower extremity revascularization. The present retrospective study investigates the clinical presentation, the infection as a cause of FAAs, the i...
journal_title：Minerva chirurgica
pub_type： 杂志文章
doi：
更新日期：2006-04-01 00:00:00
abstract：:Two cases of pancreatic cystadenocarcinoma, a very rare pathology, are reported. The authors treat the anatomopathological classification and they underline the diagnosis especially with reference to the new methods of cytologic study. Finally they consider the surgical approach that must be radical because of the pot...
journal_title：Minerva chirurgica
pub_type： 杂志文章
doi：
更新日期：1991-04-15 00:00:00
