Abstract:
INTRODUCTION:Bronchogenic carcinomas involving the carina or the tracheo-bronchial angle represents a challenging surgical procedure because of difficult surgical techniques and complex ventilation procedures. Even though surgical outcomes for this type of procedure has improved over time, the need for surgical management of patients with metastatic mediastinal nodes, that is those that are graded N2 or higher according to the TNM classification, is still controversial. EVIDENCE ACQUISITION:We searched PubMed, Embase, and CNKI for literature in English or Chinese reporting on this subject, with information on survival rates or survival curves for groups with different grades of nodal status. We then performed a meta-analysis by grouping N0 and N1 patients and compared the surgical outcomes to those graded as N2 or higher. Hazard Ratios for each study were derived from the Kaplan-Meier survival curve. EVIDENCE SYNTHESIS:Seven studies were included in this meta-analysis. The calculated hazard ratios ranged from 0.146 to 0.455. The weighted average hazard ratio for the N0/N1 group as compared to the N2/N3 group was 0.261 (CI: 0.154-0.441). The Galbraith plot confirmed the homogeneity of the studies included. CONCLUSIONS:Carinal resection and reconstruction remains a challenging surgical procedure and the rather poor surgical outcomes for patients graded as N2 or higher, according to nodal involvement points to the fact that better pre-operative management is required in terms of tumor grading, induction chemotherapy and radiotherapy to decrease the risks associated with metastatic mediastinal nodal status.
journal_name
Minerva Chirjournal_title
Minerva chirurgicaauthors
Lin H,Lu Y,Gu T,Wang Jdoi
10.23736/S0026-4733.17.07382-5subject
Has Abstractpub_date
2018-10-01 00:00:00pages
497-504issue
5eissn
0026-4733issn
1827-1626pii
S0026-4733.17.07382-5journal_volume
73pub_type
杂志文章,meta分析abstract::The Mirizzi syndrome is an unusual benign obstructive jaundice due to extrinsic mechanical compression of the common hepatic duct by gallstone impacted within the neck or cystic duct of the gallbladder. This syndrome is described either as an acute form due only to extrinsic compression of the common bile duct (type I...
journal_title:Minerva chirurgica
pub_type: 杂志文章
doi:
更新日期:1995-06-01 00:00:00
abstract::Increased survival rates after esophagectomy for cancer and the significant development of forms of therapy alternate to surgical treatment, today compel surgeons to devote far more attention to the methods will pursue in reconstructing the alimentary tract after removal of the esophagus. Nine patients with esophago-g...
journal_title:Minerva chirurgica
pub_type: 杂志文章
doi:
更新日期:1991-04-15 00:00:00
abstract::The anatomical region identified with the "head and neck region" has got the highest functional concentration of the human body and the highest incidence of malignant tumours per unit of surface. A pathology, that forced to serious and destroying surgical interventions in this area, will carry necessarily out a series...
journal_title:Minerva chirurgica
pub_type: 杂志文章
doi:
更新日期:1996-07-01 00:00:00
abstract::After an introduction on the various aetiological factors involved in toxic megacolon, its onset, medical treatment and indications to surgery, the paper describes personal experience with seven cases. The report highlights the importance of medical treatment which is recommended as the appropriate initial therapeutic...
journal_title:Minerva chirurgica
pub_type: 杂志文章
doi:
更新日期:1993-07-01 00:00:00
abstract::We report a case of diffuse diverticulosis of the gallbladder in a 32 year old patient, who presents epigastric pains and decayed general conditions. With the suspicion of a primitive tumor of the gallbladder, we make a cholecystectomy and the intraoperative histological examination shows a "diffuse diverticulosis of ...
journal_title:Minerva chirurgica
pub_type: 杂志文章
doi:
更新日期:1998-03-01 00:00:00
abstract::A rare case of massive inguinoscrotal hernia of the bladder in an obese 73-year-old man is described. The condition was successfully treated by simple repositioning of the bladder followed by abdominal wall repair. ...
journal_title:Minerva chirurgica
pub_type: 杂志文章
doi:
更新日期:1989-08-31 00:00:00
abstract:BACKGROUND:The metastasis of laryngeal nerve lymph node is mostly found in the upper-and middle esophageal cancer, the ratio of esophageal length from the upper incisors to the position where the esophageal tumor began to appear as proven via endoscopy to the height (LH) is likely to affect the possibility of detection...
journal_title:Minerva chirurgica
pub_type: 杂志文章
doi:10.23736/S0026-4733.20.08246-2
更新日期:2020-08-01 00:00:00
abstract::Postoperative infections are the most frequent complications in surgery and are the commonest cause of the lengthening of hospital stay. The purpose of this study is to prospectively evaluate the incidence and predisposing factors of postoperative infections in 1396 surgical patients admitted to our Institute from 198...
journal_title:Minerva chirurgica
pub_type: 杂志文章
doi:
更新日期:1992-07-01 00:00:00
abstract:AIM:Systematic surveys with advanced non-invasive imaging techniques have revealed that hepatic cysts are quite common in the general population. Therefore, we retrospectively examined our case series and compared it with the literature. METHODS:Between January 1990 and December 2000, 228 patients with non-parasitic l...
journal_title:Minerva chirurgica
pub_type: 杂志文章
doi:
更新日期:2004-08-01 00:00:00
abstract::The role of some so-called primary and secondary (or oligo-elements) elements in the physiopathology of the cardiocirculatory system has been well known from a number of years and they have been regularly included in the treatment protocols. Some, including K, Ca, Mg and Zn, are extremely well known and widely used in...
journal_title:Minerva chirurgica
pub_type: 杂志文章
doi:
更新日期:1993-02-01 00:00:00
abstract::A comparative experimental study was conducted on three different suture techniques for end-to-end colonic anastomoses. The development of stenosis, perivisceral adhesions and resistance to endoluminal pressure were assessed. The results show that the one layer all-coat interrupted stitch anastomosis displays less res...
journal_title:Minerva chirurgica
pub_type: 杂志文章
doi:
更新日期:1989-04-15 00:00:00
abstract:AIM:Severe obesity is a major health problem affecting more than 1,000,000 people in Italy, with a 95% failure rate of nonsurgical treatments. We report our over five-years experience with laparoscopic Roux-en-Y gastric bypass (LRYGBP), evaluating the postoperative course of the patients undergoing 3 different gastro-e...
journal_title:Minerva chirurgica
pub_type: 杂志文章
doi:
更新日期:2007-04-01 00:00:00
abstract::Infected vascular grafts are associated with very high rates of limb loss and mortality. "Classic" treatment has invariably included graft excision. Recent reports have suggested that a more conservative approach may be indicated in selected cases, leaving the graft in place and using an aggressive local treatment ass...
journal_title:Minerva chirurgica
pub_type: 杂志文章,评审
doi:
更新日期:1994-05-01 00:00:00
abstract::The Authors analyse 121 cases of patients affected by abdominal malignant tumors, who underwent a palliative operation. Although the number of the examinated cases is small, it appears clear that the longest survival requires, when possible, the removal of most of the malignant tissue. This seems to be in accordance w...
journal_title:Minerva chirurgica
pub_type: 杂志文章
doi:
更新日期:1979-02-15 00:00:00
abstract::Carcinoma of the gastric stump in patients who have undergone resection for duodenal and gastric ulcer represents a rare event which poses considerable diagnostic and therapeutic problems. 7 personal cases are examined, particular attention being paid to the utility of endoscopy, together with sampling for cytological...
journal_title:Minerva chirurgica
pub_type: 杂志文章
doi:
更新日期:1978-09-30 00:00:00
abstract::Results obtained in the surgical management of 36 cases of perforated duodenal ulcer treated between January 1976 and November 1979 are presented. A choice was made between three methods (suturing, excision plus pyloroplasty and truncular vagotomy, and Péan-Billroth resection and reconstruction) in the light of the du...
journal_title:Minerva chirurgica
pub_type: 杂志文章
doi:
更新日期:1980-10-31 00:00:00
abstract::The Authors report two cases with local recurrence after partial gastrectomy for advanced gastric carcinoma. The Authors suggest that chemo and/or radiotherapy associated with surgical treatment can improve the prognosis in some patients with recurrence. Response to chemotherapy and time elapsing before recurrence app...
journal_title:Minerva chirurgica
pub_type: 杂志文章,评审
doi:
更新日期:1992-06-15 00:00:00
abstract:BACKGROUND:Peripheral lymphadenopathy can be caused by benign disease, or it could be a manifestation of underlying hematological disease or metastasis of a yet undiagnosed malignant condition. Fine-needle aspiration cytology (FNAC) and image-guided core biopsy usually make up the first line of investigation. There are...
journal_title:Minerva chirurgica
pub_type: 杂志文章
doi:10.23736/S0026-4733.18.07752-0
更新日期:2019-06-01 00:00:00
abstract::The extensive literature on the efficacy of chlorhexidine is reviewed. Personal experience with the substance in the daily and preoperative disinfection of the hands of medical and paramedical personnel in a surgical department, and the medication of surgical wounds, over a period of one year confirmed its low toxicit...
journal_title:Minerva chirurgica
pub_type: 杂志文章
doi:
更新日期:1977-10-31 00:00:00
abstract::On the basis of a case of rectal Schwannoma and a review of the literature on this rare condition, stress is laid on the clinical features, diagnostic difficulties and indicated surgical therapy approaches. The need for radical operation, because of the tendency of the form to recur locally and because of the real pos...
journal_title:Minerva chirurgica
pub_type: 杂志文章
doi:
更新日期:1981-02-28 00:00:00
abstract::Non-hypertrophic breast ptosis are common diseases. Various degree of ptosis and different involutions of the breast tissue can condition the surgical treatment. Plastic surgery must provide the best surgical treatment in any case. ...
journal_title:Minerva chirurgica
pub_type: 杂志文章
doi:
更新日期:1994-11-01 00:00:00
abstract::Thymoma is the most common primary neoplasm of the tymus. The majority of thymomas are encapsulated masses and exhibit benign behavior. Less frequently they may be invasive, or rarely they may metastasize to distant sites. The usual clinical presentation is that of an anterior mediastinal mass found accidentally in an...
journal_title:Minerva chirurgica
pub_type: 杂志文章
doi:
更新日期:1996-09-01 00:00:00
abstract::Totally implantable central venous accesses systems are presently widely used in cancer patients. Perioperative and long-term morbidity of 750 consecutive implants performed from 1985 to 1994 were retrospectively reviewed. Our Series consisted in 616 (82.1%). Ports and 134 (17.9%) external tunnelled catheters with sub...
journal_title:Minerva chirurgica
pub_type: 杂志文章
doi:
更新日期:1996-06-01 00:00:00
abstract::The authors present two cases of patients with femoral anastomotic aneurysm treated by surgical vascular reconstruction. They underline the role of etiologic factors changing the structure of the arterial wall. The protective action of end to end anastomosis is confirmed. Finally, they recommend an early intervention ...
journal_title:Minerva chirurgica
pub_type: 杂志文章
doi:
更新日期:1992-01-01 00:00:00
abstract::Thirty-four patients who underwent carotid-subclavian bypass (64.7%), aorto-carotid bypass (17.6%), endarterectomy of subclavian artery (5.8%) or endarterectomy of innominate artery for "subclavian" or "innominate steal" syndromes, had a follow-up studies 3-8 years since surgery. All patients demonstrated originally a...
journal_title:Minerva chirurgica
pub_type: 杂志文章
doi:
更新日期:1980-08-15 00:00:00
abstract::A case of intestinal occlusion is reported caused by volvulus of Meckel's diverticulum. The etiological and clinical aspects are discussed together with their implications in terms of suitable surgical therapy. ...
journal_title:Minerva chirurgica
pub_type: 杂志文章
doi:
更新日期:1990-06-30 00:00:00
abstract::A case of spontaneous oesophageal rupture or Boerhaave syndrome is described. The absence of the typical initial vomiting together with a clinical picture that successively indicated repeated myocardial infarction, pancreatitis and pulmonary abscess delayed diagnosis by 4 days, after which emergency thoracotomy, perfo...
journal_title:Minerva chirurgica
pub_type: 杂志文章
doi:
更新日期:1990-01-01 00:00:00
abstract:BACKGROUND:Diastasis Recti Abdominis DRA is defined as an abnormally wide distance separates the two rectus muscles. Thinning and widening of the linea alba is an important risk factor for development midline hernia. In patient with DRA there is an increase rate of hernia recurrence. METHODS:We perform a retrospective...
journal_title:Minerva chirurgica
pub_type: 杂志文章
doi:10.23736/S0026-4733.20.08404-7
更新日期:2020-08-06 00:00:00
abstract::A clinical case of cloacogenic anal carcinoma is reported. These neoplasms, deriving from embryonal residuals at different levels of the ano-rectal junction, have a better prognosis than squamous carcinomas; the surgical alternative to abdomino-perineal resection is a simple local exeresis for small tumours that do no...
journal_title:Minerva chirurgica
pub_type: 杂志文章
doi:
更新日期:1989-10-15 00:00:00
abstract::Reference is made to personal experience (421 lumbar sympathectomies in 1640 vascular operations carried out over the last ten years) and the results of an enquiry addressed to more than 200 Italian surgeons are cited for the proposition that the indications for this operation are still the subject of disagreement, wh...
journal_title:Minerva chirurgica
pub_type: 杂志文章,评审
doi:
更新日期:1981-09-30 00:00:00