Abstract:
STUDY DESIGN:The efficacy of intrathecal (spinal) morphine in the treatment of pain after posterior spinal fusions was assessed. OBJECTIVE:To investigate improved posterior pain control with fewer side effects in patients with posterior spinal fusions. SUMMARY OF BACKGROUND DATA:After multilevel spinal fusion with instrumentation, patients experience considerable pain that is difficult to treat. METHODS:For this study, 65 patients undergoing elective multilevel posterior spinal instrumentation were randomized to receive spinal morphine as follows: 10 microgram/kg, 20 microgram/kg, or none. These patients were assessed after surgery for pain control and narcotic-associated complications. RESULTS:The patients who received 20 microgram/kg of spinal morphine were more comfortable immediately after surgery, remained pain free for a longer period, and required significantly less additional narcotic. These patients also had fewer respiratory complications. CONCLUSIONS:Relatively high-dose spinal morphine administration provides simple, reliable postoperative pain control after posterior spinal fusions. This may contribute to reduced postoperative respiratory morbidity and an improved outcome.
journal_name
Spine (Phila Pa 1976)journal_title
Spineauthors
Urban MK,Jules-Elysee K,Urquhart B,Cammisa FP,Boachie-Adjei Odoi
10.1097/00007632-200203010-00015keywords:
subject
Has Abstractpub_date
2002-03-01 00:00:00pages
535-7issue
5eissn
0362-2436issn
1528-1159journal_volume
27pub_type
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