Abstract：
BACKGROUND:A high compliance is an important scientific objective for a multicenter clinical trial and also an ethical responsibility. Some of non-compliance causes can be prevented during the enrollment phase by an accurate selection of subjects (quality of recruitment), other can be controlled after the recruitment, by a good organization of follow-up tests and visits (quality of organization). METHODS:The policy adopted in the Operative Center of the Delegazione Alto Lario della Lega Italiana per la Lotta contro i Tumori di Gravedona (Como) for obtaining a high compliance of women recruited in the Italian Tamoxifen Prevention Study are illustrated. RESULTS:The non-compliance rate of this center is low: 5.6 vs 23.3% of the whole Italian trial. CONCLUSIONS:The low non-compliance demonstrates the efficacy of the policy adopted.
journal_name
Minerva Medjournal_title
Minerva medicaauthors
Baratelli GM,Allio W,Lanzani A,Valsecchi P,Rotmensz Nkeywords:
subject
Has Abstractpub_date
2002-02-01 00:00:00pages
7-12issue
1eissn
0026-4806issn
1827-1669journal_volume
93pub_type
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