Nocturnal oxygen therapy in patients with the Eisenmenger syndrome.

abstract：:To investigate patterns of testing for human immunodeficiency virus (HIV) infection in tuberculosis patients, we obtained data from the tuberculosis registry and from medical records of 500 tuberculosis patients in Los Angeles County. Sixty-three percent of tuberculosis patients were tested for HIV infection, and mult...

journal_title：American journal of respiratory and critical care medicine

authors： Asch SM,London AS,Barnes PF,Gelberg L

更新日期：1997-01-01 00:00:00

abstract：RATIONALE:Although interferon (IFN)-gamma release assays are approved for the diagnosis of latent tuberculosis infection (LTBI), limited data exist regarding their performance in HIV infection. OBJECTIVES:To compare tuberculin skin test (TST) results to the commercial IFN-gamma release assay QuantiFERON-TB Gold In-Tub...

journal_title：American journal of respiratory and critical care medicine

authors： Luetkemeyer AF,Charlebois ED,Flores LL,Bangsberg DR,Deeks SG,Martin JN,Havlir DV

更新日期：2007-04-01 00:00:00

abstract：RATIONALE:There is growing evidence that resident cells, such as fibroblasts and epithelial cells, can drive the persistent accumulation of dendritic cells (DCs) in chronically inflamed tissue, leading to the organization and the maintenance of ectopic lymphoid aggregates. This phenomenon, occurring through a chemokine...

journal_title：American journal of respiratory and critical care medicine

authors： Marchal-Sommé J,Uzunhan Y,Marchand-Adam S,Kambouchner M,Valeyre D,Crestani B,Soler P

更新日期：2007-11-15 00:00:00

abstract：:Pulmonary tuberculosis, one of the granulomatous diseases, has few serological markers for its activity. Recently, an increased serum level of vascular endothelial growth factor (VEGF) was detected in patients with Crohn's disease, also a granulomatous disease. We hypothesized that VEGF might be associated with the pa...

journal_title：American journal of respiratory and critical care medicine

authors： Matsuyama W,Hashiguchi T,Matsumuro K,Iwami F,Hirotsu Y,Kawabata M,Arimura K,Osame M

更新日期：2000-09-01 00:00:00

abstract：:The absence of standardized assessment protocols with well- defined measurement properties limits comparison of outcomes among those receiving long-term oxygen therapy (LTOT). We describe simple protocols for a hospital test, a simulated home test, and an actual home test, their reliability and relationship to each ot...

journal_title：American journal of respiratory and critical care medicine

authors： Guyatt GH,McKim DA,Weaver B,Austin PA,Bryan RE,Walter SD,Nonoyama ML,Ferreira IM,Goldstein RS

更新日期：2001-03-01 00:00:00

abstract：:The aim of the study was to determine whether closing pressures or vascular distensibility can be used to describe liver venous hemodynamics when right atrial pressure is raised. The study was performed using a vascularly isolated pig liver preparation that allowed the independent control of portal vein and hepatic ar...

journal_title：American journal of respiratory and critical care medicine

authors： Brienza N,Ayuse T,O'Donnell CP,Permutt S,Robotham JL

更新日期：1995-08-01 00:00:00

abstract：:Previous studies suggest that lung function tests using monodisperse aerosols can help to identify early stages of lung diseases. We investigated intrapulmonary particle loss and aerosol bolus dispersion-a marker of convective gas transport-in 32 women with asymptomatic nonspecific bronchial hyperresponsiveness (BHR) ...

journal_title：American journal of respiratory and critical care medicine

authors： Kohlhäufl M,Brand P,Scheuch G,Meyer TS,Schulz H,Häussinger K,Heyder J

更新日期：1999-03-01 00:00:00

abstract：:It has been nearly a century since the first suggestion that a soluble factor in plasma or serum might be responsible for the symptoms of allergic disease and asthma, and more than 30 yr since immunoglobulin E (IgE) was identified as the key molecule in mediating what are now described as type 1 hypersensitivity react...

journal_title：American journal of respiratory and critical care medicine

authors： Platts-Mills TA

更新日期：2001-10-15 00:00:00

abstract：:The epidemiologic characteristics of lung cancer in Taiwan differ from those in other parts of the world in low male-to-female ratio, the high percentage of adenocarcinoma, and the relatively high percentage of nonsmokers who are victims. To investigate possible correlation between p53 gene alteration and the unique c...

journal_title：American journal of respiratory and critical care medicine

authors： Lee LN,Shew JY,Sheu JC,Lee YC,Lee WC,Fang MT,Chang HF,Yu CJ,Yang PC,Luh KT

更新日期：1994-12-01 00:00:00

abstract：RATIONALE:Obstructive sleep apnea (OSA) is common in people with hypertension, particularly resistant hypertension. Treatment with an antihypertensive agent alone is often insufficient to control hypertension in patients with OSA. OBJECTIVES:To determine whether continuous positive airway pressure (CPAP) added to trea...

journal_title：American journal of respiratory and critical care medicine

authors： Thunström E,Manhem K,Rosengren A,Peker Y

更新日期：2016-02-01 00:00:00

abstract：:Obstructive sleep apnea causes cardiovascular morbidity and premature death. Potential links between sleep apnea and cardiovascular complications are chronically elevated activity of the sympathetic nervous system and abnormal vascular function. To explore vascular function, we determined the reactive hyperemic blood ...

journal_title：American journal of respiratory and critical care medicine

authors： Imadojemu VA,Gleeson K,Quraishi SA,Kunselman AR,Sinoway LI,Leuenberger UA

更新日期：2002-04-01 00:00:00

abstract：RATIONALE:Obstructive sleep apnea (OSA) is hypothesized to be influenced by genes within pathways involved with obesity, craniofacial development, inflammation, and ventilatory control. OBJECTIVES:We conducted the first candidate gene study of OSA using family data from European Americans and African Americans, select...

journal_title：American journal of respiratory and critical care medicine

authors： Larkin EK,Patel SR,Goodloe RJ,Li Y,Zhu X,Gray-McGuire C,Adams MD,Redline S

更新日期：2010-10-01 00:00:00

abstract：RATIONALE:The incidence of influenza-associated acute respiratory failure is unknown. OBJECTIVES:To estimate the population-based incidence of influenza-associated acute respiratory failure hospitalizations. METHODS:This is a cohort study from January 2003 through March 2009 using hospitalization databases for Arizon...

journal_title：American journal of respiratory and critical care medicine

authors： Ortiz JR,Neuzil KM,Rue TC,Zhou H,Shay DK,Cheng PY,Cooke CR,Goss CH

更新日期：2013-09-15 00:00:00

abstract：:We reported that systemic keratinocyte growth factor (KGF) given before bone marrow transplantation (BMT) prevents allogeneic T cell-dependent lung inflammation assessed on Day 7 post-BMT, but the antiinflammatory effects of KGF were impaired in mice injected with both T cells and conditioning regimen of cyclophospham...

journal_title：American journal of respiratory and critical care medicine

authors： Yang S,Panoskaltsis-Mortari A,Ingbar DH,Matalon S,Zhu S,Resnik ER,Farrell CL,Lacey DL,Blazar BR,Haddad IY

更新日期：2000-11-01 00:00:00

abstract：RATIONALE:Extracellular nucleotides have recently been identified as proinflammatory mediators involved in asthma pathogenesis by signaling via purinergic receptors, but the role of the purinergic receptor type 6 (P2Y6R) has not been previously investigated. OBJECTIVES:To investigate the role of P2Y6R in asthma pathog...

journal_title：American journal of respiratory and critical care medicine

authors： Vieira RP,Müller T,Grimm M,von Gernler V,Vetter B,Dürk T,Cicko S,Ayata CK,Sorichter S,Robaye B,Zeiser R,Ferrari D,Kirschbaum A,Zissel G,Virchow JC,Boeynaems JM,Idzko M

更新日期：2011-07-15 00:00:00

abstract：:We derived reference values for slow vital capacity (VC) and flow-volume curve indexes (FVC, FEV(1), and flows) from the 1,185 tracings provided by 1,039 "normal" subjects who participated in one or both cross-sectional surveys of the Po River Delta study in 1980-1982 and in 1988-1991. Definition of "normal" was based...

journal_title：American journal of respiratory and critical care medicine

authors： Pistelli F,Bottai M,Viegi G,Di Pede F,Carrozzi L,Baldacci S,Pedreschi M,Giuntini C

更新日期：2000-03-01 00:00:00

abstract：:A respiratory therapist-driven weaning protocol incorporating daily screens, spontaneous breathing trials (SBT), and prompts to caregivers has been associated with superior outcomes in mechanically ventilated medical patients. To determine the effectiveness of this approach in neurosurgical (NSY) patients, we conducte...

journal_title：American journal of respiratory and critical care medicine

authors： Namen AM,Ely EW,Tatter SB,Case LD,Lucia MA,Smith A,Landry S,Wilson JA,Glazier SS,Branch CL,Kelly DL,Bowton DL,Haponik EF

更新日期：2001-03-01 00:00:00

abstract：:We examined the influence of gender on the polysomnographic features of obstructive sleep apnea (OSA) in a retrospective study of 830 patients with OSA diagnosed by overnight polysomnography (PSG). The severity of OSA was determined from the apnea- hypopnea index (AHI) for total sleep time (AHI(TST)), and was classifi...

journal_title：American journal of respiratory and critical care medicine

authors： O'Connor C,Thornley KS,Hanly PJ

更新日期：2000-05-01 00:00:00

abstract：RATIONALE:The determinants of immunoglobulin G (IgG) level and the risk of hypogammaglobulinemia (HGG) in patients with severe lung disease before and after lung transplantation are unknown. OBJECTIVES:We aimed to identify predictors of low IgG levels before and after lung transplantation. METHODS:We performed a retr...

journal_title：American journal of respiratory and critical care medicine

authors： Yip NH,Lederer DJ,Kawut SM,Wilt JS,D'Ovidio F,Wang Y,Dwyer E,Sonett JR,Arcasoy SM

更新日期：2006-04-15 00:00:00

abstract：:Genes for the chemokine receptors CCR5 and CCR2 are characterized by polymorphisms resulting in a nonfunctional receptor expression. Ligands for CCR2 and CCR5 (chemokines monocyte chemotactic protein-1 [MCP-1] and RANTES) are implicated in the pathogenesis of sarcoidosis. We have, therefore, analyzed polymorphisms of ...

journal_title：American journal of respiratory and critical care medicine

authors： Petrek M,Drábek J,Kolek V,Zlámal J,Welsh KI,Bunce M,Weigl E,Du Bois R

更新日期：2000-09-01 00:00:00

abstract：:To attain a better understanding of antibiotic cycling and its effects on the epidemiology of antibiotic resistance in gram-negative microorganisms, two different antibiotic classes (quinolone and beta-lactam) were cycled during four 4-month periods in a surgical intensive care unit. Respiratory aspirates and rectal s...

journal_title：American journal of respiratory and critical care medicine

authors： van Loon HJ,Vriens MR,Fluit AC,Troelstra A,van der Werken C,Verhoef J,Bonten MJ

更新日期：2005-03-01 00:00:00

abstract：:The nasal mucosal is the first site of contact with inhaled antigens. However, the nature of local immune responses and the role of nasal-associated lymphoid tissue (NALT) in those responses have rarely been studied. To characterize the cells involved in mucosally derived immune responses, NALT and Peyer's patch (PP) ...

journal_title：American journal of respiratory and critical care medicine

authors： Heritage PL,Underdown BJ,Arsenault AL,Snider DP,McDermott MR

更新日期：1997-10-01 00:00:00

abstract：RATIONALE:Tezacaftor (formerly VX-661) is an investigational small molecule that improves processing and trafficking of the cystic fibrosis transmembrane conductance regulator (CFTR) in vitro, and improves CFTR function alone and in combination with ivacaftor. OBJECTIVES:To evaluate the safety and efficacy of tezacaft...

journal_title：American journal of respiratory and critical care medicine

authors： Donaldson SH,Pilewski JM,Griese M,Cooke J,Viswanathan L,Tullis E,Davies JC,Lekstrom-Himes JA,Wang LT,VX11-661-101 Study Group.

更新日期：2018-01-15 00:00:00

abstract：:Patients with impaired pulmonary function are at increased risk for the development of postoperative complications. Recently exercise testing and predicted postoperative (ppo) function have gained increasing importance in the evaluation of lung resection candidates. We prospectively evaluated an algorithm for the preo...

journal_title：American journal of respiratory and critical care medicine

authors： Wyser C,Stulz P,Solèr M,Tamm M,Müller-Brand J,Habicht J,Perruchoud AP,Bolliger CT

更新日期：1999-05-01 00:00:00

abstract：:The respiratory-related evoked potential (RREP) is the electroencephalographic response to brief inspiratory occlusion. The P3 component of the response reflects the active cognitive processing of stimulus information. This study investigated the RREP in 16 subjects with asthma and 16 control subjects. In addition, au...

journal_title：American journal of respiratory and critical care medicine

authors： Webster KE,Colrain IM

更新日期：2002-07-01 00:00:00

abstract：:In this study, 12 male baboons were delivered by hysterotomy at 75% of gestation. The development of a nonlethal baboon model permitted a study of lung growth and development in long-term survivors. Control animals were ventilated with clinically appropriate oxygen for the 21 d study period. BPD animals were ventilate...

journal_title：American journal of respiratory and critical care medicine

authors： Coalson JJ,Winter V,deLemos RA

更新日期：1995-08-01 00:00:00

abstract：RATIONALE:Our understanding of how airway remodeling affects regional airway elastic properties is limited due to technical difficulties in quantitatively measuring dynamic, in vivo airway dimensions. Such knowledge could help elucidate mechanisms of excessive airway narrowing. OBJECTIVES:To use anatomical optical coh...

journal_title：American journal of respiratory and critical care medicine

authors： Williamson JP,McLaughlin RA,Noffsinger WJ,James AL,Baker VA,Curatolo A,Armstrong JJ,Regli A,Shepherd KL,Marks GB,Sampson DD,Hillman DR,Eastwood PR

更新日期：2011-03-01 00:00:00

abstract：RATIONALE:Respiratory syncytial virus (RSV) is an important cause of hospitalization and death in infants worldwide. Most RSV deaths occur in developing countries, where burden and risk factors for life-threatening illness are unclear. OBJECTIVES:We defined the burden of life-threatening (O(2) saturation [O(2) sat] ≤ ...

journal_title：American journal of respiratory and critical care medicine

authors： Ferolla FM,Hijano DR,Acosta PL,Rodríguez A,Dueñas K,Sancilio A,Barboza E,Caría A,Gago GF,Almeida RE,Castro L,Pozzolo C,Martínez MV,Grimaldi LA,Rebec B,Calvo M,Henrichsen J,Nocito C,González M,Barbero G,Losada JV,

更新日期：2013-05-01 00:00:00

abstract：:The objective of this study was to determine quantitative and qualitative surfactant alterations, proteins, and platelet activating factor (PAF) in bronchoalveolar lavage (BAL) fluid from patients with pulmonary thromboembolism (PTE) with respect to ventilated patients without PTE. Patients with PTE underwent BAL at t...

journal_title：American journal of respiratory and critical care medicine

authors： Nakos G,Kitsiouli EI,Lekka ME

更新日期：1998-11-01 00:00:00

abstract：:Pneumonectomized rats develop pulmonary hypertension (PH) and pulmonary vascular neointimal formation 4 wk after monocrotaline (MCT) administration. Male Sprague-Dawley rats were injected with MCT (60 mg/kg) on Day 7 after left pneumonectomy. Three groups (n = 5) received 40-O-(2-hydroxyethyl)-rapamycin (RAD, 2.5 mg/k...

journal_title：American journal of respiratory and critical care medicine

authors： Nishimura T,Faul JL,Berry GJ,Veve I,Pearl RG,Kao PN

更新日期：2001-02-01 00:00:00