Abstract：
:We have amplified and sequenced PCR products derived from 10 nuclear receptor (NR) genes from the anthozoan cnidarian Acropora millepora, including five products corresponding to genes not previously reported from the phylum Cnidaria. cDNAs corresponding to seven of these products were sequenced and at least three encode full-length proteins, increasing the number of complete cnidarian NR coding sequences from one to four. All clear orthologs of Acropora NRs either lack an activation domain or lack a known ligand, consistent with the idea that the ancestral nuclear receptor was without a ligand. Phylogenetic analyses indicate that most, and possibly all, presently identified cnidarian NRs are members of NR subfamily 2, suggesting that the common ancestor of all known nuclear receptors most resembled members of this subfamily.
journal_name
Mol Phylogenet Evoljournal_title
Molecular phylogenetics and evolutionauthors
Grasso LC,Hayward DC,Trueman JW,Hardie KM,Janssens PA,Ball EEdoi
10.1006/mpev.2001.0994keywords:
subject
Has Abstractpub_date
2001-10-01 00:00:00pages
93-102issue
1eissn
1055-7903issn
1095-9513pii
S1055790301909947journal_volume
21pub_type
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