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Linear regression analysis of inhibitory potency of organic disulfides against Histoplasma capsulatum.

Abstract：

:The Free-Wilson equations are derived for the case of symmetrical substitution and are applied, in four modifications, to in vitro inhibitory activity of 77 organic disulfides against Histoplasma capsulatum. Substituent constants are listed to aid in the design of new inhibitory agents against this human pathogen (and perhaps other fungal organisms).

journal_name

J Med Chem

journal_title

Journal of medicinal chemistry

authors

Schaad LJ,Werner RH,Dillon L,Field L,Tate CE

doi

10.1021/jm00238a004

keywords:

subject

Has Abstract

pub_date

1975-04-01 00:00:00

pages

344-51

issue

4

eissn

0022-2623

issn

1520-4804

journal_volume

18

pub_type

杂志文章

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