Abstract：
BACKGROUND AND AIMS:The use of steroids was recently extended to the various forms of ulcerative rectocolitis by the introduction of topical formulations, above all steroids with an hepatic "first pass" devoid of systemic interference. The aim of this study was to evaluate the efficacy and tolerability of Beclomethasone dipropionate (BDP) in a rectal foam formulation, in the treatment of patients suffering from ulcerative colitis. METHODS:The experimental protocol took the form of a 28-day open prospective trial using BDP rectal foam in patients suffering from ulcerative colitis. Endoscopic, histological, clinical and tolerability parameters were evaluated. The centres taking part in the trial collected data for 60 cases out of a total of 80 patients enrolled in the study, of both sexes and aged between 20 and 81 years old, suffering from proctosigmoiditis (46.7%) and ulcerative rectocolitis (53.3%). RESULTS:Endoscopic parameters showed an improvement after 28 days of treatment in 74.5% of patients; a clinical improvement was achieved in 65.2% of cases. In percentage terms of the mean value of all the improved parameters, histological parameters were altered in 56.9% of patients. With regard to tolerability 82% of patients judged the treatment to be good/excellent. CONCLUSIONS:In conclusion, in line with recent reports regarding other pharmaceutical forms of BDP, including the use of rectal foam, these data confirm the efficacy and tolerability of this molecule and emphasise the validity of its use in the treatment of ulcerative colitis and proctosigmoiditis.
journal_name
Minerva Chirjournal_title
Minerva chirurgicaauthors
Arcidiacono R,Zanasi G,Pirone Z,Borzio M,Borzio F,Milano G,Cestari L,Ravelli P,Terraroli C,de Franchis R,Vecchi M,Galeone M,Toti GL,Cacioli D,Luminari L,Giannelli C,Gioiemi A,Russello D,Di Blasi M,Di Stefano A,Ruskeywords:
subject
Has Abstractpub_date
1999-09-01 00:00:00pages
635-44issue
9eissn
0026-4733issn
1827-1626journal_volume
54pub_type
临床试验,杂志文章,多中心研究abstract：:Hemangiopericytoma is a rare and solitary solid tumor originating from pericytes, which are contractile pericapillary cells, first identified and described by Zimmermann in 1923. This neoplasm occurs most commonly in the lower extremities and retroperitoneum. The Authors describe the case of a patient affected with a ...
journal_title：Minerva chirurgica
pub_type： 杂志文章
doi：
更新日期：1993-06-30 00:00:00
abstract：:We have reported two patients with unilateral adrenal hyperplasia as a rare cause of primary aldosteronism, and discussed the literature on this subject. When diagnosed by NMR-CT imaging and selective sampling from adrenal veins, the treatment of this disorder appears to be surgical. Whether its pathogenesis is relate...
journal_title：Minerva chirurgica
pub_type： 杂志文章,评审
doi：
更新日期：1995-01-01 00:00:00
abstract：:The aim of this work is to assess the list of fine needle aspiration in the diagnosis of lesions of the parotid. Thirty-nine patients suffering from parotid pathology were subjected to cytology examination through fine needle aspiration. Thirty seven patients subjected to surgical operation have a histological compari...
journal_title：Minerva chirurgica
pub_type： 杂志文章,评审
doi：
更新日期：1993-10-31 00:00:00
abstract：INTRODUCTION:Bronchogenic carcinomas involving the carina or the tracheo-bronchial angle represents a challenging surgical procedure because of difficult surgical techniques and complex ventilation procedures. Even though surgical outcomes for this type of procedure has improved over time, the need for surgical managem...
journal_title：Minerva chirurgica
pub_type： 杂志文章,meta分析
doi：10.23736/S0026-4733.17.07382-5
更新日期：2018-10-01 00:00:00
abstract：:The aim of the paper is to give a contribution to the understanding of the role of surgery in patients with N3 lung cancer. The A. describe their results on 32 patients with N3 lung cancer operated on mediastinectomy; histological examination of the specimens showed 27 squamous cell carcinomas and 5 adenocarcinomas. T...
journal_title：Minerva chirurgica
pub_type： 杂志文章
doi：
更新日期：1995-12-01 00:00:00
abstract：:The incidence and prevalence of obesity continues to increase globally. Physicians will therefore provide care for an increasing number of obese patients in their clinical practice. Optimal management of these patients is required to minimize the risk of perioperative complications that increase morbidity and mortalit...
journal_title：Minerva chirurgica
pub_type： 杂志文章,评审
doi：10.23736/S0026-4733.17.07310-2
更新日期：2017-06-01 00:00:00
abstract：:A case of volvulus of ectopic spleen mistaken for twisted ovarian cyst is described. Attention is drawn to six points: 1) the rarity of the condition; 2) the persistent uncertainty concerning its aetiopathogenesis, even though over a century has passed since the first case was reported; 3) the mechanism leading to twi...
journal_title：Minerva chirurgica
pub_type： 杂志文章
doi：
更新日期：1977-04-15 00:00:00
abstract：:Angina-like chest pain, caused by alterations of esophageal function, is an increasingly common occurrence confronting cardiologists: advances in pathogenetic knowledge and in diagnostic possibilities in this field have in fact shed light on the prevalence of esophageal angina, which is present in approximately 60% of...
journal_title：Minerva chirurgica
pub_type： 杂志文章,评审
doi：
更新日期：1991-04-15 00:00:00
abstract：:Pancreatoblastoma is a very rare tumor of the pancreas, affecting children in the first decade of life. Ultrasound and CT scan may be useful but pre-operative diagnosis is often quite difficult. High level of seric alpha-fetoprotein could be suggestive of pancreatoblastoma. The definitive diagnosis is however made by ...
journal_title：Minerva chirurgica
pub_type： 杂志文章
doi：
更新日期：1996-09-01 00:00:00
abstract：:The Authors report a case of benign mucocele which was brought to their attention for emergency treatment. Following a review of the literature, they examine the clinical, anatomopathological, pathogenetic and therapeutic problems related to this rare disease. In conclusion, it is important to assess the benign nature...
journal_title：Minerva chirurgica
pub_type： 杂志文章
doi：
更新日期：1990-10-31 00:00:00
abstract：:Open Nissen fundoplication has been established as an effective treatment in the management of gastroesophageal reflux disease (GORD). Progress in minimally invasive surgery has given the chance of performing laparoscopic Nissen fundoplication. The short-term results are encouraging and its outcome promising. The need...
journal_title：Minerva chirurgica
pub_type： 杂志文章,评审
doi：
更新日期：2001-08-01 00:00:00
abstract：AIM:The aim of this study was to assess retrospectively at 5 years the clinical outcome of bone regeneration in patients who underwent maxillary sinus lift with different equine-derived, enzyme-deantigenated equine bone grafts, and simultaneous placement of acid-etched surface implants. METHODS:Eighteen patients (10 m...
journal_title：Minerva chirurgica
pub_type： 杂志文章
doi：
更新日期：2008-04-01 00:00:00
abstract：:A case of entero-vesical fistula in Crohn's disease is presented. Clinical manifestations, diagnostic means and surgical treatment of the lesion are discussed. ...
journal_title：Minerva chirurgica
pub_type： 杂志文章
doi：
更新日期：1994-07-01 00:00:00
abstract：:A case of a young male operated on for acute appendicitis due to a carcinoid of the base is reported. Since the tumor was infiltrating the resection margin of the appendix, the patient was later treated with a right hemicolectomy. Carcinoid tumor is unusual, but can be encountered several times during the career of a ...
journal_title：Minerva chirurgica
pub_type： 杂志文章
doi：
更新日期：2000-01-01 00:00:00
abstract：:Although a wide variety of extrathoracic pathologies may be associated to tracheo-pulmonary lesions, this paper draws attention to tumour pathologies due to their frequency and the difficulties involved in their treatment in relation to the question of "whether to carry out treatment" as well as the importance of timi...
journal_title：Minerva chirurgica
pub_type： 杂志文章,评审
doi：
更新日期：1993-08-01 00:00:00
abstract：:Authors personal experience during ten years in surgery Oddi's sphincter is reported. Indications and technique of papillosphincteroplasty and wirsungsphincteroplasty are described; results obtained in 504 surgical treatment of PSP (combined with WSP in 121 cases) are referred; failures and complications are described...
journal_title：Minerva chirurgica
pub_type： 杂志文章
doi：
更新日期：1981-10-15 00:00:00
abstract：:A case series of 5 male patients afflicted with breast carcinoma is reported. The Authors describe symptomatology, diagnostic iter, principles of surgical treatment and results. Underlined is the wider surgical demolition in male breast cancer in comparison with females, even if natural history and biological conduct ...
journal_title：Minerva chirurgica
pub_type： 杂志文章
doi：
更新日期：1990-09-15 00:00:00
abstract：AIM:Anorectal dysfunction is routinely treated at the Center for Pelvic Floor Rehabilitation, San Giovanni University Hospital, Turin, Italy. Of a total of 147 patients treated between April 2007 and May 2008, 44 (30%) received pelvic floor rehabilitation following anorectal surgery. With this study we wanted to evalua...
journal_title：Minerva chirurgica
pub_type： 杂志文章
doi：
更新日期：2009-04-01 00:00:00
abstract：:The authors report a case of popliteal artery adventitial cystic disease. They discuss diagnosis and treatment. ...
journal_title：Minerva chirurgica
pub_type： 杂志文章
doi：
更新日期：1990-11-01 00:00:00
abstract：:Explorative laparotomies and palliative surgery for pancreatic carcinoma have been reduced due to improved diagnostic tools, the spread of laparoscopic techniques and the growing use of external biliary drainage and endoprostheses. By comparing two successive observation periods the authors point out that, owing to th...
journal_title：Minerva chirurgica
pub_type： 杂志文章
doi：
更新日期：1993-12-01 00:00:00
abstract：:Small cell carcinoma of the esophagus is a rare tumor. It was described for the first time in 1952 by McKeown and 200 cases have been reported till now. Because of its similarity with small cell carcinoma of the lung, the treatment of this tumor is controversial. In our Institute we treated three patients with small c...
journal_title：Minerva chirurgica
pub_type： 杂志文章
doi：
更新日期：2003-08-01 00:00:00
abstract：:Ward nurses have a central role in postoperative pain management. Pain medication is prescribed by anesthetists and surgeons, but it is ward nurses who spend more time with patients and have the responsibility for assessing patient's pain intensity, administering some prescribed analgesic treatments and monitoring the...
journal_title：Minerva chirurgica
pub_type： 杂志文章
doi：
更新日期：2003-12-01 00:00:00
abstract：:The authors report a retrospective study of four patients treated for sigmoid volvulus at the Clinica Chirurgica II of IRCCS Policlinico S. Matteo of Pavia between April 1974 and June 1989. They are collected from a series of 74 consecutive operations for colonic obstruction not related to hernias of the inguinal-crur...
journal_title：Minerva chirurgica
pub_type： 杂志文章,评审
doi：
更新日期：1993-05-31 00:00:00
abstract：:Uniportal Video-Assisted Thoracic Surgery (uniportal VATS) lobectomy represents the last evolution of minimally invasive techniques for the surgical treatment of lung cancer. Uniportal VATS was developed from two-ports approach, with two main advantages: only one intercostal space is damaged and the direct view to the...
journal_title：Minerva chirurgica
pub_type： 杂志文章,评审
doi：
更新日期：2016-02-01 00:00:00
abstract：AIM:The aim of the present study was to prospectively evaluate the Stretta radiofrequency (RF) treatment for gastroesophageal reflux disease (GERD) -related respiratory symptoms over a 5-years follow-up period. METHODS:A total of 132 patients underwent the Stretta procedure between April 2007 and February 2009; 122 of...
journal_title：Minerva chirurgica
pub_type： 杂志文章
doi：
更新日期：2014-10-01 00:00:00
abstract：:The factors underlying late thrombosis of aortobifemoral by-pass are analysed on the basis of personal experience and reported data. They are considered to be due to progressive degradation of the prosthesic tissue and, particularly, to the lack of an adequate back flow route, apart from any faults in the actual const...
journal_title：Minerva chirurgica
pub_type： 杂志文章
doi：
更新日期：1979-02-28 00:00:00
abstract：:The authors present a case of bilateral adrenal pheochromocytoma that occurred at their observation and surgically treated with a bilateral adrenalectomy. The authors review the literature in order to discuss the diagnostic and therapeutic option to treat these cases. They stress the importance of preoperative abdomin...
journal_title：Minerva chirurgica
pub_type： 杂志文章,评审
doi：
更新日期：1997-05-01 00:00:00
abstract：:Mucocele of the appendix is a rare lesion (only 0;2-0.3% of all appendicectomies). It is characterized by distension of the lumen within mucus. Mucoceles are often asymptomatic and are discovered as an incidental finding either at surgery or during barium edema. There have been reports of other tumors associated with ...
journal_title：Minerva chirurgica
pub_type： 杂志文章
doi：
更新日期：1995-12-01 00:00:00
abstract：BACKGROUND:Surgeon's position during open cholecystectomy operation has been standardized since more than 100 years, being traditionally fixed at the right side of the patient. Only a few French authors adopted the "left location" just for the time requested for the common bile duct exploration. METHODS:In this paper ...
journal_title：Minerva chirurgica
pub_type： 杂志文章
doi：
更新日期：1998-07-01 00:00:00
abstract：:The authors report the own experience about the experimental use of tissue adhesive in the colonic surgery, on 14 rabbits, with quite satisfactory result. Therefore they evince that this tissue adhesive, althought it can't replace the surgical suture, yet it can help the surgeon out of a hard colonic anastomosis. ...
journal_title：Minerva chirurgica
pub_type： 杂志文章
doi：
更新日期：1980-05-15 00:00:00
