Silencing of Long Non-Coding RNA (LncRNA) Non-Coding RNA Activated by DNA Damage (NORAD) Inhibits Proliferation, Invasion, Migration, and Promotes Apoptosis of Glioma Cells via Downregulating the Expression of AKR1B1.

abstract：BACKGROUND:Component mal-positioning may contribute to a poor clinical outcome after hemiarthroplasty. Eccentric head components, recently introduced, allow posterior offset of the humeral head relative to the shaft so the purpose of this study was to determine effects of mal-aligning humeral head offset. MATERIAL/MET...

journal_title：Medical science monitor : international medical journal of experimental and clinical research

authors： McMahon PJ,Dee DT,Yang BY,Lee TQ

更新日期：2003-08-01 00:00:00

abstract：BACKGROUND:To examine the effect of probiotics as adjunctive therapy for the treatment of rheumatoid arthritis (RA). A sample size of 30 subjects was calculated to determine a moderate effect. MATERIAL/METHODS:A three month double-blind, placebo-controlled study was performed using probiotic Lactobacillus rhamnosus GR...

journal_title：Medical science monitor : international medical journal of experimental and clinical research

authors： Pineda Mde L,Thompson SF,Summers K,de Leon F,Pope J,Reid G

更新日期：2011-06-01 00:00:00

abstract：BACKGROUND:The role of nitric oxide (NO) in the modulation of basal and insulin-stimulated glucose uptake remains controversial. The aim of this study was to investigate the role of NO released from its donors, S-nitrosoglutathione (GSNO) and S-nitroso-N-acetylpenicillamine (SNAP), on glucose uptake in skeletal muscle ...

journal_title：Medical science monitor : international medical journal of experimental and clinical research

authors： McGrowder D,Ragoobirsingh D,Brown P

更新日期：2006-01-01 00:00:00

abstract：:BACKGROUND This study investigated the effect of occupational stress and circadian clock gene polymorphism on sleep disorder of oil workers in Xinjiang, China. MATERIAL AND METHODS We enrolled 2300 Xinjiang oil workers who had been working for at least 1 year. The Chinese revised version of the Occupational Stress Que...

journal_title：Medical science monitor : international medical journal of experimental and clinical research

authors： Ning L,Shi L,Tao N,Li R,Jiang T,Liu J

更新日期：2020-08-01 00:00:00

abstract：BACKGROUND:The humanized anti-HER2 monoclonal antibody trastuzumab (Herceptin) is useful in the treatment of ErbB2-overexpressing breast cancers, but its efficiency is limited because development of resistance is common. In order to study the possibility of improving the efficacy of therapies directed against HER2/erbB...

journal_title：Medical science monitor : international medical journal of experimental and clinical research

authors： Camirand A,Lu Y,Pollak M

更新日期：2002-12-01 00:00:00

abstract：:BACKGROUND It has been reported that overt and mild thyroid dysfunctions are associated with insulin resistance (IR). We performed this retrospective study to evaluate the relationships between thyroid-stimulating hormone (TSH) levels within the reference range and IR. MATERIAL AND METHODS A total of 447 outpatients w...

journal_title：Medical science monitor : international medical journal of experimental and clinical research

authors： Zhu P,Liu X,Mao X

更新日期：2018-01-17 00:00:00

abstract：:BACKGROUND In previous studies, higher expression of PREX1 (PtdIns (3,4,5)P3-dependent Rac exchanger 1) has been detected in some subsets of breast cancer, and activation of PREX1 has been associated with tumor progression in vivo. However, an association between PREX1 and breast cancer prognosis has not been examined...

journal_title：Medical science monitor : international medical journal of experimental and clinical research

authors： Zhong Y,Zhang J,Zhou Y,Mao F,Lin Y,Xu Y,Guan J,Shen S,Pan B,Wang C,Peng L,Huang X,Li Y,Cao X,Sun Q

更新日期：2019-09-01 00:00:00

abstract：:BACKGROUND Recent research suggests that abnormal Ca2+ handling plays a role in the occurrence and maintenance of atrial fibrillation (AF). Therefore, Ca2+ release and ingestion depend on properties of the ryanodine receptor (RyR) and sarcoplasmic reticulum Ca2+ATPase2a (SERCA2a). This study aimed to detect whether SE...

journal_title：Medical science monitor : international medical journal of experimental and clinical research

authors： Wang HL,Zhou XH,Li ZQ,Fan P,Zhou QN,Li YD,Hou YM,Tang BP

更新日期：2017-08-16 00:00:00

abstract：BACKGROUND:The aim of this study was to determine the expression of apoptotic factors Bax, Bcl-2, and Caspase-3 in lens epithelial cells (LECs) from cataracts secondary to pars plana vitrectomy with silicone oil (SO) tamponade. We also investigated the impact of SO emulsification on the expression of apoptotic factors....

journal_title：Medical science monitor : international medical journal of experimental and clinical research

authors： Zhu L,Zhao K,Lou D

更新日期：2016-03-09 00:00:00

abstract：:BACKGROUND Lung cancer is among the most common causes of cancer-related deaths worldwide, but its tumorigenic mechanisms are largely unknown. Long non-coding RNAs (LncRNAs) have been shown to have significant roles in multiple cancers. Herein, we aimed to elucidate the detailed effects of a newly-discovered LncRNA, t...

journal_title：Medical science monitor : international medical journal of experimental and clinical research

authors： Su P,Wang F,Qi B,Wang T,Zhang S

更新日期：2017-04-11 00:00:00

abstract：BACKGROUND:We used an animal model of experimental varicocele to investigate the effects on the ipsilateral testis during the progression of experimental varicocele in rat. MATERIAL/METHODS:Experimental varicocele was induced by partial ligation of the left renal vein in rats. Rats in each control group were subjected...

journal_title：Medical science monitor : international medical journal of experimental and clinical research

authors： Zheng Y,Zhang X,Zhou J,Cheng F,Zhou B

更新日期：2008-06-01 00:00:00

abstract：:BACKGROUND Cardiac resynchronization therapy (CRT) is efficacious in the treatment of chronic heart failure (CHF); however, because it is non-physiological, some patients are unresponsive. The present study used rate-adaptive atrioventricular delay (RAAVD) to track the physiological atrioventricular delay and investig...

journal_title：Medical science monitor : international medical journal of experimental and clinical research

authors： Zhao L,Zhao L,Pu L,Hua B,Wang Y,Li S,Li Q,Guo T

更新日期：2017-08-17 00:00:00

abstract：BACKGROUND:Cnidium lactone is a natural coumarin compound that can inhibit a variety of cancer cell proliferation and induce cancer cell apoptosis. This experiment investigated the effect of cnidium lactone on molecular marker expression in prostate cancer nude mice to study its effect in inducing apoptosis. MATERIAL ...

journal_title：Medical science monitor : international medical journal of experimental and clinical research

authors： Bi D,Yang M,Zhao X,Huang S

更新日期：2015-08-18 00:00:00

abstract：BACKGROUND:Epstein-Barr virus (EBV) was isolated in the 1960s from the African childhood tumor, Burkitt's Lymphoma (BL), characterized by the translocation of the c-myc gene into one of the immunoglobulin loci. Due to the extreme discrepancy between the widespread dissemination of EBV infection and the overall rarity o...

journal_title：Medical science monitor : international medical journal of experimental and clinical research

authors： Niller HH,Salamon D,Ilg K,Koroknai A,Banati F,Bauml G,Rucker O,Schwarzmann F,Wolf H,Minarovits J

更新日期：2003-01-01 00:00:00

abstract：MATERIAL AND METHODS:In 12 Wistar rats the gross and microscopic structure of haemolymph splenic nodes was assessed after splenectomy and the obtained results were compared with those in the control group. RESULTS:It was found that splenectomy leads to generalised morphological changes of the mentioned nodes, includin...

journal_title：Medical science monitor : international medical journal of experimental and clinical research

authors： Slusarczyk K,Marniok B,Rudnicki P

更新日期：2000-07-01 00:00:00

abstract：:BACKGROUND The choice for instrumentation with minimally invasive transforaminal lumbar interbody fusion (MIS-TLIF) in treatment of degenerative lumbar disorders (DLD) remains controversial. The goal of this study was to investigate clinical outcomes in consecutive patients with multi-segment DLD treated with unilater...

journal_title：Medical science monitor : international medical journal of experimental and clinical research

authors： Liu X,Li G,Wang J,Zhang H

更新日期：2015-11-25 00:00:00

abstract：:BACKGROUND During total knee arthroplasty (TKA) in varus knee deformities, reduction osteotomy (RO) and medial soft tissue release are alternative techniques to aid in achieving deformity correction. In this study, we investigated the effect of RO compared to extensive medial soft tissue release (ER) on clinical outco...

journal_title：Medical science monitor : international medical journal of experimental and clinical research

authors： Zan P,Fan L,Liu K,Yang Y,Hu S,Li G

更新日期：2017-08-07 00:00:00

abstract：BACKGROUND:High-frequency oscillations (ripples) are proposed to be involved in memory consolidation. Ripple oscillations persist in the absence of chemical synaptic transmission and inhibitors of gapjunctions were shown to block high-frequency oscillations in hippocampal slices. In this study we investigated the effec...

journal_title：Medical science monitor : international medical journal of experimental and clinical research

authors： Hosseinzadeh H,Asl MN,Parvardeh S,Tagi Mansouri SM

更新日期：2005-03-01 00:00:00

abstract：:BACKGROUND In recent years, the incidence of gastric cancer (GC) has been increasing worldwide. Emerging evidence shows that microRNAs (miRs) may be involved in the pathogenesis of GC. Thus, this study explored the mediatory role of miR-495 in GC chemosensitivity, and investigated the mechanism by which it affects the...

journal_title：Medical science monitor : international medical journal of experimental and clinical research

authors： Li N,Han M,Zhou N,Tang Y,Tang XS

更新日期：2018-08-27 00:00:00

abstract：BACKGROUND:To examine changes in medicine utilization and prescription trends for diabetic (DM) and hypertensive (HT) patients upon initiation of the National Health Insurance (NHI) global budget (GB) program in Taiwan. MATERIAL/METHODS:Data on hospital-based outpatient prescriptions for DM and HT from the Taipei bran...

journal_title：Medical science monitor : international medical journal of experimental and clinical research

authors： Chou CC,Hu KY,Wu NR,Cheng YH,Loh CH,Yeh MK

更新日期：2008-05-01 00:00:00

abstract：BACKGROUND:The aim of the study was to investigate whether children born small for gestational age without other complications nor signs of neurological impairment or developmental delay before 18 months of age may display neuropsychological impairments later in life. MATERIAL/METHODS:Neuropsychological outcome, schoo...

journal_title：Medical science monitor : international medical journal of experimental and clinical research

authors： Viggedal G,Lundalv E,Carlsson G,Kjellmer I

更新日期：2004-01-01 00:00:00

abstract：:BACKGROUND Gemcitabine plus cisplatin (GP) is a novel regimen of induction chemotherapy (IC) for treating locoregional advanced nasopharyngeal cancer (NPC). This retrospective study aimed to compare the efficacy of GP and TP (paclitaxel plus cisplatin) regimens in tumor volume reduction after IC. MATERIAL AND METHODS ...

journal_title：Medical science monitor : international medical journal of experimental and clinical research

authors： Zheng L,Liao W,Xu P,Li B,Wen H,Zhang S

更新日期：2018-11-08 00:00:00

abstract：:BACKGROUND Neonatal acute respiratory distress syndrome (ARDS) is a common clinical syndrome caused by lung immaturity and the abnormal synthesis of pulmonary surfactant in preterm newborns, and it has high morbidity and mortality rates. The present study investigated the roles of interleukin-37 (IL-37) in the pathoge...

journal_title：Medical science monitor : international medical journal of experimental and clinical research

authors： Li B,Ji X,Tian F,Gong J,Zhang J,Liu T

更新日期：2020-03-10 00:00:00

abstract：BACKGROUND:The common and effective treatment for degenerative lumbar diseases is lumbar spinal fusion. Controversy still exists on the choice for instrumentation with spinal fusion procedures. Therefore, we conducted this meta-analysis exclusively of RCTs to compare the clinical outcomes of patients receiving bilatera...

journal_title：Medical science monitor : international medical journal of experimental and clinical research

authors： Li X,Lv C,Yan T

更新日期：2015-03-16 00:00:00

abstract：:BACKGROUND This population study aimed to investigate the demographic and clinical characteristics and outcome of cases of coronavirus disease 2019 in Lu'an City, China between January 22, 2020 and February 18, 2020 identified from the China Information System for Disease Control and Prevention (CISDCP). MATERIAL AND ...

journal_title：Medical science monitor : international medical journal of experimental and clinical research

authors： Jiang Z,Sun J,Li X,Lyu Y

更新日期：2020-08-14 00:00:00

abstract：BACKGROUND:This study aimed to decrease the massive problem of cataract-related blindness and visual disability in rural areas of Yemen and reach more visually impaired and blind people to provide them with an improved standard of visual rehabilitation. MATERIAL/METHODS:From January 1999 to June 2006, 181,123 patients...

journal_title：Medical science monitor : international medical journal of experimental and clinical research

authors： Bamashmus MA,Al-Barrag AO

更新日期：2008-11-01 00:00:00

abstract：:BACKGROUND Not all patients with spinal cord compression due to cervical spondylotic myelopathy (CSM) have clinical symptoms and signs. The aim of this study was to investigate and compare the imaging findings in asymptomatic and symptomatic patients with CSM with mild to moderate cervical spinal cord compression. MAT...

journal_title：Medical science monitor : international medical journal of experimental and clinical research

authors： Cao JM,Zhang JT,Yang DL,Yang YP,Xia HH,Yang L

更新日期：2017-10-13 00:00:00

abstract：:BACKGROUND More and more patients with lung adenocarcinoma were detected with ground glass nodule (GGN) due to the popularity of low-dose spiral computed tomography (LDCT) recently. The clinicopathological characteristics and epidermal growth factor receptor (EGFR) mutation features were unclear. MATERIAL AND METHODS ...

journal_title：Medical science monitor : international medical journal of experimental and clinical research

authors： Xu Y,Zheng M,Wang N,Wang R

更新日期：2019-11-11 00:00:00

abstract：:BACKGROUND Liver cancer is the third leading cause of tumor-related deaths worldwide. Stomatin-like protein 2 (STOML2) is obviously upregulated in various tumors. In this study, we explored the potential roles and mechanisms of si-STOML2 in the migration and invasion of human hepatoma LM3 cells. MATERIAL AND METHODS T...

journal_title：Medical science monitor : international medical journal of experimental and clinical research

authors： Zhu W,Li W,Geng Q,Wang X,Sun W,Jiang H,Pu X

更新日期：2018-10-25 00:00:00

abstract：:BACKGROUND The long non-coding RNA (lncRNA) metastasis-associated lung adenocarcinoma transcript 1 (MALAT1) is expressed highly in various types of tumors. Moreover, the tumor-initiating role of MALAT1 has been probed in the context of breast cancer. This study was set to investigate the regulatory role of MALAT1 on t...

journal_title：Medical science monitor : international medical journal of experimental and clinical research

authors： Yu J,Jin T,Zhang T

更新日期：2020-07-05 00:00:00