Abstract:
:Despite considerable progress in paediatric HIV treatment and timely revision of global policies recommending the use of more effective and tolerable antiretroviral regimens, optimal antiretroviral formulations for infants, children, and adolescents remain limited. The Paediatric Antiretroviral Drug Optimization group reviews medium-term and long-term priorities for antiretroviral drug development to guide industry and other stakeholders on formulations most needed for low-income and middle-income countries. The group convened in December, 2018, to assess progress since the previous meeting and update the list of priority formulations. Issues relating to drug optimisation for neonatal prophylaxis and paediatric treatment, and those relating to the investigation of novel antiretrovirals in adolescents and pregnant and lactating women were also discussed. Continued focus on identifying, prioritising, and providing access to optimal antiretroviral formulations suitable for infants, children, and adolescents is key to ensuring that global HIV treatment targets can be met.
journal_name
Lancet HIVjournal_title
The lancet. HIVauthors
Penazzato M,Townsend CL,Rakhmanina N,Cheng Y,Archary M,Cressey TR,Kim MH,Musiime V,Turkova A,Ruel TD,Rabie H,Sugandhi N,Rojo P,Doherty M,Abrams EJ,PADO4 participants.doi
10.1016/S2352-3018(19)30193-6subject
Has Abstractpub_date
2019-09-01 00:00:00pages
e623-e631issue
9eissn
2405-4704issn
2352-3018pii
S2352-3018(19)30193-6journal_volume
6pub_type
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