Abstract：
:Secondary malignancy of the penis is a rare clinical condition, often associated with disseminated genitourinary malignancies. The prognosis is poor and the treatment options include penectomy, local surgical excision, radiation therapy, chemotherapy and supportive therapy. Neither of these therapeutic options lead to superior treatment outcomes in the literature. The authors report the case of a 66 year-old man with a metastasis to the glans penis from a rectal adenocarcinoma, diagnosed two years after radical treatment for primary disease. The patient underwent palliative treatment with radiotherapy and chemotherapy, remaining asymptomatic and disease-free at one year follow-up. Close follow-up of patients with history of rectal adenocarcinoma is very important. Radiochemotherapy is a feasible and effective therapeutic option for penile metastasis, addressing both disease control and symptomatic improvement. :A doença secundária do pénis é uma situação clínica frequentemente associada a doença disseminada e as localizações mais comuns são os órgãos genito-urinários. O prognóstico é mau e as opções de tratamento incluem: penectomia; excisão local; radioterapia; quimioterapia; terapêutica de suporte. Apesar das várias terapêuticas existentes, nenhuma na literatura é apontada como superior àsrestantes. Os autores documentam o caso de um doente de 66 anos com metástase da glande peniana em contexto de adenocarcinoma do recto, diagnosticada dois anos após o tratamento da doença primária. O doente foi submetido a tratamento paliativo com radio-quimioterapia e permanece assintomático e livre de doença após um ano de seguimento. O follow-up apertado dos doentes com neoplasia do recto é mandatório. A radio-quimioterapia é uma abordagem válida, com bom controlo da doença e melhoria sintomática.
journal_name
Acta Med Portjournal_title
Acta medica portuguesaauthors
Nunes B,Matias M,Alves A,Jorge Mdoi
10.20344/amp.5775subject
Has Abstractpub_date
2015-07-01 00:00:00pages
525-7issue
4eissn
0870-399Xissn
1646-0758journal_volume
28pub_type
杂志文章abstract：INTRODUCTION:Female Urinary Incontinence (UI) is a major public health issue given its high prevalence and its physical, psychological and social impact on women's lives. The aim of this study was to determine the prevalence and impact of Stress Urinary Incontinence (SUI) before and during pregnancy in parturients from...
journal_title：Acta medica portuguesa
pub_type： 杂志文章
doi：
更新日期：2006-09-01 00:00:00
abstract：INTRODUCTION:Outpatient antimicrobial therapy programs have been in place for more than four decades. They provide safe and effective treatment for a selected group of patients while reducing costs. In Europe in general, and in Portugal in particular, these programs are still a relatively new phenomenon. The aim of thi...
journal_title：Acta medica portuguesa
pub_type： 杂志文章
doi：10.20344/amp.11730
更新日期：2019-09-02 00:00:00
abstract：INTRODUCTION:The concept of resilience refers to the possibility of individuals to develop positively when exposed to situations of adversity or stress. This is a complex process involving the interaction of vulnerability and protection factors. Researching resilience only makes sense when applied to populations consid...
journal_title：Acta medica portuguesa
pub_type： 杂志文章
doi：
更新日期：2011-12-01 00:00:00
abstract：BACKGROUND:Breast cancer is the most frequent malignant tumor and the leading cause of cancer death in women in Portugal. Due to its relation to an increase in distant metastasis and subsequent death, loco-regional relapse is one major concern in breast cancer women. Several classic prognostic factors as tumour size, n...
journal_title：Acta medica portuguesa
pub_type： 杂志文章
doi：
更新日期：2012-03-01 00:00:00
abstract：INTRODUCTION:The consumption of potentially inappropriate medicines is high among institutionalized elderly, predisposing to potential drug interactions, adverse drug events, risk of iatrogenic cascade, increased morbidity and mortality and health costs. Medication review is a promising strategy for therapeutic optimiz...
journal_title：Acta medica portuguesa
pub_type： 杂志文章
doi：10.20344/amp.13030
更新日期：2020-07-30 00:00:00
abstract：:After the discovery of insulin and during almost an half of a century, physicians and researchers apply their efforts in a better knowledge to reduce the perinatal mortality of the offspring of the diabetic mother. The optimisation of glucose control--the main key of the management of diabetic pregnancy--and the new m...
journal_title：Acta medica portuguesa
pub_type： 杂志文章,评审
doi：
更新日期：2002-05-01 00:00:00
abstract：:Modern medicine has many roots on greco-roman practice of the medical art. The authors analyse the work De Medicina by Aulus Cornelius Celsus. They look upon the nature of the medical knowledge, the principles of ethics, causality and describe the mental disorders (phrenitis, depression, third insanity, seizure disord...
journal_title：Acta medica portuguesa
pub_type： 传,历史文章,杂志文章
doi：
更新日期：2007-09-01 00:00:00
abstract：:Essencial Thrombocytemia is a rare chronic myeloproliferative disease of unknown etiology, characterized by markedly elevated platelet production (> 600,000/ml). It is more frequent among women above 50 years of age and may be associated with hemorrhagic or thrombotic tendencies. The authors report a case of Essencial...
journal_title：Acta medica portuguesa
pub_type： 杂志文章
doi：
更新日期：2003-03-01 00:00:00
abstract：:A new case of nephrotoxic effect of Maneb is related. The patient used this product as fungicide and developed a progressive illness with acute renal failure. The study by light and electron microscopy revealed severe tubular lesions that disappeared some months later with tubular cell regeneration. However, in spite ...
journal_title：Acta medica portuguesa
pub_type： 杂志文章
doi：
更新日期：1989-08-01 00:00:00
abstract：:Biomedical simulation is an effective educational complement for healthcare training, both at undergraduate and postgraduate level. It enables knowledge, skills and attitudes to be acquired in a safe, educationally orientated and efficient manner. In this context, simulation provides skills and experience that facilit...
journal_title：Acta medica portuguesa
pub_type： 杂志文章
doi：10.20344/amp.8403
更新日期：2016-12-30 00:00:00
abstract：INTRODUCTION:Biological and biosimilar medicinal products have specific characteristics that call for a closer monitoring of their safety profile. Since the current legal framework stems from both European and national regulations, some gaps in the operational field may be expected. The goal of this paper is to identif...
journal_title：Acta medica portuguesa
pub_type： 杂志文章
doi：10.20344/amp.8079
更新日期：2017-03-31 00:00:00
abstract：INTRODUCTION:In the context of a pronounced population ageing and rising mortality due to chronic illnesses, this national epidemiological study compares the places where people die with population preferences. MATERIAL AND METHODS:Data on numbers of deaths in 2010 by gender, age group, region of residence NUTS II and...
journal_title：Acta medica portuguesa
pub_type： 杂志文章
doi：
更新日期：2013-07-01 00:00:00
abstract：:In order to assess the weight of Rheumatic Diseases, the Authors retrospectively studied 117 patients admitted to the Internal Medicine Service of the Faro District Hospital over a 3 year period (1989-1991). The selection criterion comprised the final rheumatological diagnosis. The diseases were arranged in nosologica...
journal_title：Acta medica portuguesa
pub_type： 杂志文章
doi：
更新日期：1993-07-01 00:00:00
abstract：INTRODUCTION:Vaccines prevent more cases of diseases than any other medical treatment. However, information on new vaccines introduced in the market and not included in the National Vaccination Program (NVP) is often sparse, and their knowledge limited. OBJECTIVES:Evaluate general and specific knowledge of healthy chi...
journal_title：Acta medica portuguesa
pub_type： 杂志文章
doi：
更新日期：2011-12-01 00:00:00
abstract：INTRODUCTION:In Portugal child abuse is a reality, although its true incidence is still unknown. POPULATION AND METHODS:Retrospective study by consulting child abuse processes of children hospitalized in Paediatric Nursery and Neonatal Special Care Unit of Centro Hospitalar de Setúbal, E.P.E between January 1, 2006 an...
journal_title：Acta medica portuguesa
pub_type： 杂志文章
doi：
更新日期：2010-05-01 00:00:00
abstract：BACKGROUND:The large wounds of the body wall, due to traumas, removal of tumors or prolonged laparostomies are a difficult surgical challenge with complex treatment. This paper presents the efficacy of the closure of large surgical wounds using rubber elastic bands. METHODS:One or two circular rubber elastic bands wer...
journal_title：Acta medica portuguesa
pub_type： 杂志文章
doi：
更新日期：2011-05-01 00:00:00
abstract：INTRODUCTION:The Power of Food Scale measures appetite for, rather than consumption of, palatable foods - a construct frequently designated as hedonic hunger. The purpose of this study was to examine the psychometric properties of a Portuguese version of the Power of Food Scale, namely reliability and construct validit...
journal_title：Acta medica portuguesa
pub_type： 杂志文章
doi：10.20344/amp.6517
更新日期：2015-09-01 00:00:00
abstract：:A case of angiosarcoma, Raynaud's disease and arteriovenous malformation of the intestinal tract is presented. We propose the association of these three vascular diseases, which has not yet been described. The study of more cases is important in order to understand the physiopathological mechanisms involved. ...
journal_title：Acta medica portuguesa
pub_type： 杂志文章,评审
doi：
更新日期：1994-02-01 00:00:00
abstract：:The Internal Medicine consultation plays an important part in the activity of the Medicine Department. This activity is seldom quantified and is usually underestimated. In order to assess the work load represented by this service, the authors designed a prospective study to quantify and analyse the characteristics of ...
journal_title：Acta medica portuguesa
pub_type： 杂志文章
doi：
更新日期：2004-07-01 00:00:00
abstract：INTRODUCTION:PFAPA syndrome (Periodic Fever, Aphthous stomatitis, Pharyngitis, Adenitis) is a benign sporadic syndrome of unknown cause and an important diagnosis to consider in the child with recurrent fever and tonsillitis. OBJECTIVES:To describe the presentation, age of onset, time until diagnosed, episode duration...
journal_title：Acta medica portuguesa
pub_type： 杂志文章
doi：
更新日期：2011-01-01 00:00:00
abstract：:Literature analysis has been controversial about pre-eclampsia. It is known that not pregnant patients should be treated due cardiovascular benefits. However, the real benefits of antihypertensive treatment in pre-eclampsia were not demonstrated. Yet, there are many drugs that can be used for antihypertensive treatmen...
journal_title：Acta medica portuguesa
pub_type： 杂志文章,评审
doi：
更新日期：2008-07-01 00:00:00
abstract：INTRODUCTION:Metals are a common cause of allergic contact dermatitis. After the introduction of the EU Nickel Directive (1994/27/CE; 2004/96/EC) and, more recently, the Cement Directive (2003/53/EC) there has been a significant decrease in sensitization to metals mainly in the Nordic countries. The applicability of th...
journal_title：Acta medica portuguesa
pub_type： 杂志文章
doi：
更新日期：2014-05-01 00:00:00
abstract：:Labour is very important in breech presentation and it is associated to significant morbidity and mortality enhancement in recent years. The authors made a retrospective study of breech presentation and labour with this kind of fetal presentation, in Santa Maria Hospital in 1993 and analysed the following data: matern...
journal_title：Acta medica portuguesa
pub_type： 杂志文章
doi：
更新日期：1999-04-01 00:00:00
abstract：:The objective of this manuscript is to discuss the existing barriers for the dissemination of medical guidelines, and to present strategies that facilitate the adaptation of the recommendations into clinical practice. The literature shows that it usually takes several years until new scientific evidence is adopted in ...
journal_title：Acta medica portuguesa
pub_type： 杂志文章
doi：
更新日期：2009-01-01 00:00:00
abstract：OBJECTIVE:To compare the haemodynamic measurements of cardiac output (CO), central venous pressure (CVP), pulmonary capillary wedge pressure (Pw) and pulmonary artery systolic pressure (PASP), obtained by Swan-Ganz catheter and transthoracic echocardiography. MATERIAL AND METHODS:Prospective study in a Medical/Surgica...
journal_title：Acta medica portuguesa
pub_type： 杂志文章
doi：
更新日期：2006-05-01 00:00:00
abstract：:Neuropsychiatric symptoms are commonly associated with chronic hepatitis C virus infection (HCV). The aim of this review of the literature was to evaluate the prevalence of depression in patients with hepatitis C, as well as the proposed etiopathogenic models. A review of the literature was undertaken using the comple...
journal_title：Acta medica portuguesa
pub_type： 杂志文章,评审
doi：
更新日期：2006-01-01 00:00:00
abstract：:Twelve cases of extreme umbilical blood flow impairement (8 cases with loss of end-diastolic blood flow and 4 cases with reversed flow) found among 658 pregnancies studied by continuous Doppler between April 1st 1989 and March 31st 1990, are reported. The findings were associated to intra-uterine growth retardation (9...
journal_title：Acta medica portuguesa
pub_type： 杂志文章
doi：
更新日期：1991-05-01 00:00:00
abstract：INTRODUCTION:There is no international consensus regarding gestational diabetes mellitus diagnostic criteria. In Portugal, the Carpenter and Coustan criteria were replaced by an adaptation of the International Association of Diabetes and Pregnancy Study Groups criteria. Our aim was to compare the incidence and outcomes...
journal_title：Acta medica portuguesa
pub_type： 杂志文章
doi：10.20344/amp.10135
更新日期：2018-08-31 00:00:00
abstract：:Multiple risk factors for cardiovascular disorders, particularly hypercholesterolemia, are often present in hypertensive patients. Several studies have shown that antihypertensive drugs affect the lipid profile, increasing the risk of cardiovascular diseases. Here, it was investigated the lipoprotein metabolism altera...
journal_title：Acta medica portuguesa
pub_type： 杂志文章
doi：
更新日期：2008-11-01 00:00:00
abstract：:Multiple sclerosis (MS) is a chronic neuroinflammatory autoimmune disease believed to arise from complex interactions of both environmental and genetic factors. As in other complex diseases with autoimmune features, a genetic association with the human leukocyte antigen (HLA) complex is well documented. Association...
journal_title：Acta medica portuguesa
pub_type： 杂志文章,评审
doi：
更新日期：2012-07-01 00:00:00
