Abstract：
:Silica (SiO2) nanoparticles (NPs) have found extensive applications in industrial manufacturing, biomedical and biotechnological fields. Therefore, the increasing exposure to such ultrafine particles requires studies to characterize their potential cytotoxic effects in order to provide exhaustive information to assess the impact of nanomaterials on human health. The understanding of the biological processes involved in the development and maintenance of a variety of pathologies is improved by genome-wide approaches, and in this context, gene set analysis has emerged as a fundamental tool for the interpretation of the results. In this work we show how the use of a combination of gene-by-gene and gene set analyses can enhance the interpretation of results of in vitro treatment of A549 cells with Ludox® colloidal amorphous silica nanoparticles. By gene-by-gene and gene set analyses, we evidenced a specific cell response in relation to NPs size and elapsed time after treatment, with the smaller NPs (SM30) having higher impact on inflammatory and apoptosis processes than the bigger ones. Apoptotic process appeared to be activated by the up-regulation of the initiator genes TNFa and IL1b and by ATM. Moreover, our analyses evidenced that cell treatment with LudoxÒ silica nanoparticles activated the matrix metalloproteinase genes MMP1, MMP10 and MMP9. The information derived from this study can be informative about the cytotoxicity of Ludox® and other similar colloidal amorphous silica NPs prepared by solution processes.
journal_name
Int J Environ Res Public Healthauthors
Fede C,Millino C,Pacchioni B,Celegato B,Compagnin C,Martini P,Selvestrel F,Mancin F,Celotti L,Lanfranchi G,Mognato M,Cagnin Sdoi
10.3390/ijerph110908867subject
Has Abstractpub_date
2014-08-28 00:00:00pages
8867-90issue
9eissn
1661-7827issn
1660-4601pii
ijerph110908867journal_volume
11pub_type
杂志文章abstract：:In this work, we explored a novel approach to integrate both geo-environmental and soil geomechanical parameters in a landslide susceptibility model. A total of 179 shallow to deep landslides were identified using Google Earth images and field observations. Moreover, soil geomechanical properties of 11 representative ...
journal_title：International journal of environmental research and public health
pub_type： 杂志文章
doi：10.3390/ijerph17186795
更新日期：2020-09-17 00:00:00
abstract：:Per- and polyfluoroalkyl substances (PFAS) are pollutants that have demonstrated a high level of environmental persistence and are very difficult to remediate. As the body of literature on their environmental effects has increased, so has regulatory and research scrutiny. The widespread usage of PFAS in industrial app...
journal_title：International journal of environmental research and public health
pub_type： 杂志文章,评审
doi：10.3390/ijerph17218117
更新日期：2020-11-03 00:00:00
abstract：:This study assessed the differences between immigrants and natives in terms of combined effects of sugar-sweetened beverage (SSB) or snack consumption and preventive behaviors for severe early childhood caries (SECC) through a large-scale survey of 31,565 native and 1046 immigrant child⁻parent pairs in Taiwan. Childre...
journal_title：International journal of environmental research and public health
pub_type： 杂志文章
doi：10.3390/ijerph16061047
更新日期：2019-03-22 00:00:00
abstract：:This paper examines existing research on the impact of terrorism on expatriate coping strategies. We consider pre-assignment fear of terrorism, in-country coping strategies, and anxiety and posttraumatic stress disorder (PTSD) associated with repatriation. The extant research is small but growing. Our model for expatr...
journal_title：International journal of environmental research and public health
pub_type： 杂志文章
doi：10.3390/ijerph14070808
更新日期：2017-07-19 00:00:00
abstract：:Depression is a major mental health problem during adolescence. This study, using a sample of Chinese adolescents, examined the separate and combined effects of perceived school-related stress and of family socioeconomic status (SES) on the prevalence of depressive symptoms. A total of 1774 Chinese students from Grade...
journal_title：International journal of environmental research and public health
pub_type： 杂志文章
doi：10.3390/ijerph110606085
更新日期：2014-06-10 00:00:00
abstract：:Tobacco smoke air pollution (TSAP) measurement may persuade parents to adopt smoke-free homes and thereby reduce harm to children from tobacco smoke in the home. In a pilot study involving 29 smoking families, a Sidepak was used to continuously monitor home PM(2.5) during an 8-h period, Sidepak and/or Dylos monitors p...
journal_title：International journal of environmental research and public health
pub_type： 杂志文章
doi：10.3390/ijerph121214970
更新日期：2015-11-30 00:00:00
abstract：:This study aimed to determine the injury prevention-, safety education-, and violence-related factors pertaining to tooth fracture experience (TFE) in Korean adolescents. We used data from the 14th Korea Youth Risk Behavior Survey (KYRBS) in 2018. The 60,040 participants were selected using a complex sampling design f...
journal_title：International journal of environmental research and public health
pub_type： 杂志文章
doi：10.3390/ijerph17228556
更新日期：2020-11-18 00:00:00
abstract：:Over the last decade, the lives of children in several countries, including Greece, have been affected by recession. The aim of the present study was (a) to examine time trends in physical activity (PA) and screen time (ST) of Greek preschool children, together with their family affluence (FA), from 2009 until 2018, a...
journal_title：International journal of environmental research and public health
pub_type： 杂志文章
doi：10.3390/ijerph17051645
更新日期：2020-03-03 00:00:00
abstract：:Dialysis nurses face complex and demanding working conditions. Due to demographic changes, the number of dialysis patients has increased, while the number of skilled personnel is expected to decrease, leading to tremendous increases in quantitative demands in the near future. Against the background of increasing workl...
journal_title：International journal of environmental research and public health
pub_type： 杂志文章
doi：10.3390/ijerph17030802
更新日期：2020-01-28 00:00:00
abstract：:Most governments strive for an ecological civilization so the efficiency of government expenditure on environmental protection (EPEE) is an important issue. While it is recognized that foreign direct investment (FDI) enhances environmental protection, this investigation focuses on the effects of FDI on the efficiency ...
journal_title：International journal of environmental research and public health
pub_type： 杂志文章,评审
doi：10.3390/ijerph16142496
更新日期：2019-07-12 00:00:00
abstract：:Litter, the link between soil and plant, is an important part of nutrient return to soil. Deeply understanding the effect of litter decomposition on soil microbiological properties is important for the sustainable development of grasslands. Three plants (Thymus quinquecostatus Celak., Stipa bungeana Trin. and Artemisi...
journal_title：International journal of environmental research and public health
pub_type： 杂志文章
doi：10.3390/ijerph15091797
更新日期：2018-08-21 00:00:00
abstract：:Indoor air pollution is an increasing health concern, especially in enclosed environments such as underground subway stations because of increased global usage by urban populations. This study measured the indoor air quality of underground platforms at 10 metro stations of the Taipei Rapid Transit system (TRTS) in Tai...
journal_title：International journal of environmental research and public health
pub_type： 杂志文章
doi：10.3390/ijerph13121200
更新日期：2016-12-02 00:00:00
abstract：:A traditional structural analysis of scaffolding structures requires loading conditions that are only possible during design, but not in operation. Thus, this study proposes a method that can be used during operation to make an automated safety prediction for scaffolds. It implements a divide-and-conquer technique wit...
journal_title：International journal of environmental research and public health
pub_type： 杂志文章
doi：10.3390/ijerph17072391
更新日期：2020-04-01 00:00:00
abstract：:Australian Aboriginal pregnant women have a high smoking prevalence (45%). Health professionals lack adequate educational resources to manage smoking. Resources need to be tailored to ensure saliency, cultural-sensitivity and account for diversity of Indigenous populations. As part of an intervention to improve health...
journal_title：International journal of environmental research and public health
pub_type： 杂志文章
doi：10.3390/ijerph14101148
更新日期：2017-09-29 00:00:00
abstract：:Short-term exposure to fire smoke, especially particulate matter with an aerodynamic diameter less than 2.5 µm (PM2.5), is associated with adverse health effects. In order to quantify the impact of prescribed burning on human health, a general health impact function was used with exposure fields of PM2.5 from prescrib...
journal_title：International journal of environmental research and public health
pub_type： 杂志文章
doi：10.3390/ijerph16132312
更新日期：2019-06-29 00:00:00
abstract：:Exposure to lead-containing dusts is a global public health concern. This work addresses an important issue of whether eco-friendly water-based paints reduce the exposure potential of auto-repainting workers to metals. With this aim, metal levels in automobile paints and worker metal exposure were measured using both ...
journal_title：International journal of environmental research and public health
pub_type： 杂志文章
doi：10.3390/ijerph15050899
更新日期：2018-05-03 00:00:00
abstract：:In Taiwan, migrants come mostly for marriage and work. Several researchers have conducted health-related studies of marital migrants and migrant workers, but the access of the two groups to healthcare has not been studied. Therefore, our study investigated the factors associated with migrants' access to healthcare, wi...
journal_title：International journal of environmental research and public health
pub_type： 杂志文章
doi：10.3390/ijerph16162830
更新日期：2019-08-08 00:00:00
abstract：:Individuals with severe physical impairments have difficulties operating electric wheelchairs (EWs), especially in situations where fine steering abilities are required. Automatic driving partly solves the problem, although excessive reliance on automatic driving is not conducive to maintaining their residual physical...
journal_title：International journal of environmental research and public health
pub_type： 杂志文章
doi：10.3390/ijerph17155502
更新日期：2020-07-30 00:00:00
abstract：INTRODUCTION:Patient support groups (PSGs) should be designed according to the backgrounds of participants and the nature of their diseases. Using health literacy as an outcome indicator for PSGs is rare. METHODS:All questionnaires (Mandarin Multidimensional Health Literacy Questionnaire, MMHLQ) were collected from ei...
journal_title：International journal of environmental research and public health
pub_type： 杂志文章
doi：10.3390/ijerph17165702
更新日期：2020-08-07 00:00:00
abstract：:Due to the expensive cost and uncertain effectiveness of environmental management options in eliminating pharmaceutical residues, recently, decreasing the emission of pharmaceutical pollutants from a drug administration perspective has been considered a hot area of research. As a kind of drug administration for the en...
journal_title：International journal of environmental research and public health
pub_type： 杂志文章
doi：10.3390/ijerph16081463
更新日期：2019-04-25 00:00:00
abstract：:The deregulation of the autonomic nervous system assessed through the heart rate variability (HRV) analysis is a promising pathway linking work stress and cardiovascular diseases. We aim to investigate the associations between HRV High Frequency (HF) and Low Frequency (LF) powers and work stress in a sample of 36 heal...
journal_title：International journal of environmental research and public health
pub_type： 杂志文章
doi：10.3390/ijerph15010113
更新日期：2018-01-11 00:00:00
abstract：:In this study, a semi-quantitative occupational chemical exposure risk prediction model, based on the calculation of exposure hazard indexes, was proposed, corrected, and applied to a national chemical exposure databank. The model comprises one factor used to describe toxicity (i.e., the toxicity index), and two facto...
journal_title：International journal of environmental research and public health
pub_type： 杂志文章
doi：10.3390/ijerph10083157
更新日期：2013-07-25 00:00:00
abstract：:Previous research showed a positive relationship between physical activity and self-regulation in older children and adolescents, but few publications focused on young children. Therefore, the purpose of this review was to examine the impact of physical activity (PA) on the cognitive aspects of self-regulation (inhibi...
journal_title：International journal of environmental research and public health
pub_type： 杂志文章
doi：10.3390/ijerph17186576
更新日期：2020-09-09 00:00:00
abstract：:Reducing sedentary behavior in the workplace has become an important public health priority; however, some employers have expressed concerns regarding the potential for reduced productivity if employees are not seated while at work. Therefore, the aim of this study was to determine the relationship between workplace s...
journal_title：International journal of environmental research and public health
pub_type： 杂志文章
doi：10.3390/ijerph17186535
更新日期：2020-09-08 00:00:00
abstract：:With both cost and safety taken into account in the context of the life-threatening COVID-19 pandemic globally, rural tourism is expected to be the top choice for Chinese residents for relaxation and enhancing parent-child relationships. In this paper, a structural equation (SEM) model was proposed to compare risk kno...
journal_title：International journal of environmental research and public health
pub_type： 杂志文章
doi：10.3390/ijerph17103514
更新日期：2020-05-18 00:00:00
abstract：:Introduction: Phylloides tumours (PTs) are rare fibroepithelial neoplasms that account for 0.3⁻0.9% of all breast tumours. These tumours typically occur in women aged 30⁻70 years. The occurrence of these tumours in older children and adolescents poses particular diagnostic and therapeutic problems. However, early diag...
journal_title：International journal of environmental research and public health
pub_type：
doi：10.3390/ijerph15050959
更新日期：2018-05-11 00:00:00
abstract：:This study aimed to compare the training load of a professional under-19 soccer team (U-19) to that of an elite adult team (EAT), from the same club, during the in-season period. Thirty-nine healthy soccer players were involved (EAT [n = 20]; U-19 [n = 19]) in the study which spanned four weeks. Training load (TL) was...
journal_title：International journal of environmental research and public health
pub_type： 杂志文章
doi：10.3390/ijerph18020558
更新日期：2021-01-11 00:00:00
abstract：:The transfer of pesticide residues from herbal teas to their infusion is a subject of particular interest. In this study, a multi-residue analytical method for the determination of pyrethroids (fenpropathrin, beta-cypermethrin, lambda-cyhalothrin, and fenvalerate) in honeysuckle, chrysanthemum, wolfberry, and licorice...
journal_title：International journal of environmental research and public health
pub_type： 杂志文章
doi：10.3390/ijerph14101157
更新日期：2017-09-30 00:00:00
abstract：:The purpose of the present study was to examine the effects of height-adjustable standing desks on time-series variation in sedentary behavior (SB) among primary school children. Thirty-eight children aged 11-12 years (22 boys and 16 girls) from two classes at a primary school in Nagano, Japan, participated in this st...
journal_title：International journal of environmental research and public health
pub_type： 杂志文章
doi：10.3390/ijerph16111892
更新日期：2019-05-29 00:00:00
abstract：:Metals, stress, and sociodemographics are commonly studied separately for their effects on birth outcomes, yet often jointly contribute to adverse outcomes. This study analyzes two methods for measuring cumulative risk to understand how maternal chemical and nonchemical stressors may contribute to small for gestationa...
journal_title：International journal of environmental research and public health
pub_type： 杂志文章
doi：10.3390/ijerph16193700
更新日期：2019-10-01 00:00:00
