Second malignant neoplasms following radiotherapy.

Abstract:

:More than half of all cancer patients receive radiotherapy as a part of their treatment. With the increasing number of long-term cancer survivors, there is a growing concern about the risk of radiation induced second malignant neoplasm [SMN]. This risk appears to be highest for survivors of childhood cancers. The exact mechanism and dose-response relationship for radiation induced malignancy is not well understood, however, there have been growing efforts to develop strategies for the prevention and mitigation of radiation induced cancers. This review article focuses on the incidence, etiology, and risk factors for SMN in various organs after radiotherapy.

authors

Kumar S

doi

10.3390/ijerph9124744

subject

Has Abstract

pub_date

2012-12-18 00:00:00

pages

4744-59

issue

12

eissn

1661-7827

issn

1660-4601

pii

ijerph9124744

journal_volume

9

pub_type

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