Abstract:
BACKGROUND:The widespread use of primary coronary intervention (PCI) has significantly improved the prognosis of men presenting with acute coronary syndromes, but the cardiovascular event rate among women has either levelled off or increased. The purpose of the present prospective study was to compare the clinical outcome of women and men presenting with ST-elevation myocardial infarction (STEMI) undergoing primary PCI with concomitant usage of GP IIb/IIIa inhibitors. METHODS:Between January 2006 and December 2007, 297 consecutive patients presenting with STEMI were prospectively included in this single center investigation. Overall, 82 (27.6%) women and 215 (72.4%) men were treated by PCI with additional bare metal stent implantation and a GP IIb/IIIa inhibitor. RESULTS:Women were significantly older (65 ± 10 vs 60 ± 12 years, p = 0.04), presented with a smaller reference luminal diameter (2.83 ± 0.51 vs 2.94 ± 0.43, p = 0.03) and had a higher prevalence of hypertension (68% vs 53%, p = 0.025) and obesity (30% vs 18%, p = 0.03). The incidence of major adverse cardiac events (MACE, defined as death, re-myocardial infarction, target lesion revascularization and coronary artery bypass graft) during long-term follow-up was similar in women and men (20% vs 26%, p = 0.29). Age, C-reactive protein, platelet count and cardiogenic shock were identified as independent predictors for MACE, whereas gender was not predictive. CONCLUSIONS:In this study, female gender did not emerge as an independent predictor for MACE, but women presenting with STEMI had a higher cardiovascular risk profile; this emphasizes the need for a more extensive therapeutic strategy. Combination therapy with primary PCI and GP IIb/IIIa inhibitors might mitigate gender-related differences in clinical outcomes.
journal_name
Cardiol Jjournal_title
Cardiology journalauthors
Kralev S,Hennig O,Lang S,Kälsch T,Borggrefe M,Dempfle CE,Süselbeck Tsubject
Has Abstractpub_date
2010-01-01 00:00:00pages
580-6issue
6issn
1897-5593journal_volume
17pub_type
杂志文章abstract:BACKGROUND:The second-generation cryoballoon (CB2) provides effective and durable pulmonary vein isolation (PVI) associated with encouraging and reproducible clinical outcome data. The latest- -generation cryoballoon (CB3) incorporates a 40% shorter distal tip, thus allowing for an increased rate of PVI real-time signa...
journal_title:Cardiology journal
pub_type: 杂志文章
doi:10.5603/CJ.a2018.0056
更新日期:2019-01-01 00:00:00
abstract:BACKGROUND:Catheter directed thrombolysis (CDT) and thrombectomy represent well established techniques for the treatment of intermediate pulmonary embolism (IPE). The long-term effect of catheter directed thrombolysis of IPE is unknown. METHODS:Clinical, interventional and echocardiographic data from 80 consecutive pa...
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journal_title:Cardiology journal
pub_type: 杂志文章,评审
doi:
更新日期:2011-01-01 00:00:00
abstract:BACKGROUND:Research on cardiac rehabilitation has raised interesting methods and effects without however establishing the share of the profits according to age, sex and cardiac pathology. Yet today, this disease with various pathologies strikes people of all ages and both sexes, and the recommended rehabilitation exerc...
journal_title:Cardiology journal
pub_type: 杂志文章
doi:10.5603/cj.2011.0026
更新日期:2011-01-01 00:00:00
abstract:BACKGROUND:Reperfusion therapy is known to improve prognosis and limit myocardial damage after myocardial infarction (MI). The administration of antiplatelet drugs prior to percutaneous coronary intervention also proves beneficial to patients with acute MI (AMI). However, a good number of AMI patients do not receive re...
journal_title:Cardiology journal
pub_type: 杂志文章
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abstract:BACKGROUND:Prediction of functional myocardial recovery post acute myocardial infarction should be based not only on flow patency of the infarct related artery (IRA) but also on the quality of microcirculation in at-risk segments. Myocardial blush grade (MBG) is a method of perfusion assessment which has an established...
journal_title:Cardiology journal
pub_type: 杂志文章
doi:
更新日期:2008-01-01 00:00:00
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journal_title:Cardiology journal
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doi:
更新日期:2009-01-01 00:00:00
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journal_title:Cardiology journal
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doi:
更新日期:2008-01-01 00:00:00
abstract:BACKGROUND:Coronary arteriography is still widely accepted as a gold standard for the diagnosis of coronary artery disease (CAD), despite emerging methods such as multi-slice computed tomography. None of the presently available non-invasive diagnostic tests is perfect. The aim of the article was to make a comparison of...
journal_title:Cardiology journal
pub_type: 杂志文章
doi:
更新日期:2007-01-01 00:00:00
abstract::A 25 year-old female with a history of Caesarian section ten weeks ago presented with symptoms suggestive of pulmonary embolism. Transthoracic echocardiography revealed a free-floating large thrombus traversing the right atrial cavity. Transesophageal echocardiography confirmed the presence of an unattached thrombus t...
journal_title:Cardiology journal
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doi:
更新日期:2010-01-01 00:00:00
abstract:BACKGROUND:Left ventricular non-compaction cardiomyopathy (LVNC) features extensive trabeculations. Involvement of the right ventricle (RV) has been reported; however, distinction from normal RV trabeculation is difficult. This study aimed at assessing RV morphology and function in LVNC by cardiac magnetic resonance (C...
journal_title:Cardiology journal
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journal_title:Cardiology journal
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journal_title:Cardiology journal
pub_type: 杂志文章
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更新日期:2011-01-01 00:00:00
abstract::Cardiac resynchronization therapy (CRT) is an important advance for the treatment of end-stage heart failure (HF). About 15-50% of HF is complicated by atrial fibrillation (AF), associated with worsened outcomes. The presence of AF may interfere with optimal delivery of CRT due to competition with biventricular (BiV) ...
journal_title:Cardiology journal
pub_type: 杂志文章,评审
doi:
更新日期:2009-01-01 00:00:00
abstract::Cardiac resynchronization therapy (CRT) is electrical resynchronization of the ventricles. Bachmann's bundle (BB) pacing is considered to be electrical resynchronization of the atria. Atrial fibrillation (AF) and congestive heart failure (HF) often coexist in the same patient. A 69 year-old man who underwent CRT combi...
journal_title:Cardiology journal
pub_type: 杂志文章
doi:
更新日期:2009-01-01 00:00:00
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journal_title:Cardiology journal
pub_type: 临床试验,杂志文章
doi:
更新日期:2011-01-01 00:00:00
abstract::N/A. ...
journal_title:Cardiology journal
pub_type: 信件
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更新日期:2017-01-01 00:00:00
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pub_type: 杂志文章
doi:10.5603/CJ.a2014.0085
更新日期:2015-01-01 00:00:00
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journal_title:Cardiology journal
pub_type: 杂志文章
doi:10.5603/CJ.a2017.0055
更新日期:2017-01-01 00:00:00
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journal_title:Cardiology journal
pub_type: 杂志文章
doi:
更新日期:2009-01-01 00:00:00
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journal_title:Cardiology journal
pub_type: 杂志文章
doi:10.5603/CJ.a2013.0058
更新日期:2014-01-01 00:00:00
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pub_type: 杂志文章
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doi:10.5603/CJ.a2017.0076
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pub_type: 杂志文章
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更新日期:2014-01-01 00:00:00
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pub_type: 杂志文章
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更新日期:2014-01-01 00:00:00
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pub_type: 杂志文章,多中心研究
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更新日期:2014-01-01 00:00:00
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pub_type: 杂志文章
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pub_type: 杂志文章,随机对照试验
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更新日期:2019-01-01 00:00:00
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journal_title:Cardiology journal
pub_type: 杂志文章
doi:
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