Abstract:
BACKGROUND:Functional electrical stimulation (FES) has been used to improve function in individuals with hemiparesis following stroke. An ideal functional electrical stimulation (FES) system needs an accurate mathematical model capable of designing subject and task-specific stimulation patterns. Such a model was previously developed in our laboratory and shown to predict the isometric forces produced by the quadriceps femoris muscles of able-bodied individuals and individuals with spinal cord injury in response to a wide range of clinically relevant stimulation frequencies and patterns. The aim of this study was to test our isometric muscle force model on the quadriceps femoris, ankle dorsiflexor, and ankle plantar-flexor muscles of individuals with post-stroke hemiparesis. METHODS:Subjects were seated on a force dynamometer and isometric forces were measured in response to a range of stimulation frequencies (10 to 80-Hz) and 3 different patterns. Subject-specific model parameter values were obtained by fitting the measured force responses from 2 stimulation trains. The model parameters thus obtained were then used to obtain predicted forces for a range of frequencies and patterns. Predicted and measured forces were compared using intra-class correlation coefficients, r2 values, and model error relative to the physiological error (variability of measured forces). RESULTS:Results showed excellent agreement between measured and predicted force-time responses (r2 >0.80), peak forces (ICCs>0.84), and force-time integrals (ICCs>0.82) for the quadriceps, dorsiflexor, and plantar-fexor muscles. The model error was within or below the +95% confidence interval of the physiological error for >88% comparisons between measured and predicted forces. CONCLUSION:Our results show that the model has potential to be incorporated as a feed-forward controller for predicting subject-specific stimulation patterns during FES.
journal_name
J Neuroeng Rehabiljournal_title
Journal of neuroengineering and rehabilitationauthors
Kesar TM,Ding J,Wexler AS,Perumal R,Maladen R,Binder-Macleod SAdoi
10.1186/1743-0003-5-7subject
Has Abstractpub_date
2008-02-27 00:00:00pages
7issn
1743-0003pii
1743-0003-5-7journal_volume
5pub_type
杂志文章abstract:BACKGROUND:Quantitative evaluation of position control ability in stroke patients is needed. Here we report a demonstration of position control ability assessment and test-retest reliability during squat-stand activity on a new system in hemiparetic patients and controls. METHODS:Sixty-two healthy adults and thirty-fo...
journal_title:Journal of neuroengineering and rehabilitation
pub_type: 杂志文章
doi:10.1186/1743-0003-10-37
更新日期:2013-04-15 00:00:00
abstract:BACKGROUND:To promote early rehabilitation of walking, gait training can start even when patients are on bed rest. Supine stepping in the early phase after injury is proposed to maximise the beneficial effects of gait restoration. In this training paradigm, mechanical loading on the sole of the foot is required to mimi...
journal_title:Journal of neuroengineering and rehabilitation
pub_type: 杂志文章
doi:10.1186/1743-0003-11-159
更新日期:2014-11-28 00:00:00
abstract:BACKGROUND:Published reports suggest a disparity between perceived and actual balance abilities, a trait associated with increased fall-risk in older adults. We investigate whether it is possible to 'recalibrate' these disparities using a novel gaming intervention. METHODS:We recruited 26 older adults for a 4-week int...
journal_title:Journal of neuroengineering and rehabilitation
pub_type: 临床试验,杂志文章
doi:10.1186/s12984-018-0369-8
更新日期:2018-03-22 00:00:00
abstract:BACKGROUND:When humans perform rhythmic upper and lower limb locomotor-like movements, there is an excitatory effect of upper limb exertion on lower limb muscle recruitment. To investigate potential neural mechanisms for this behavioral observation, we developed computer simulations modeling interlimb neural pathways a...
journal_title:Journal of neuroengineering and rehabilitation
pub_type: 杂志文章
doi:10.1186/1743-0003-7-59
更新日期:2010-12-10 00:00:00
abstract:BACKGROUND:Cervical spondylotic myelopathy (CSM) is a degenerative cervical disease in which the spinal cord is compressed. Patients with CSM experience balance disturbance because of impaired proprioception. The weighting of the sensory inputs for postural control in patients with CSM is unclear. Therefore, this study...
journal_title:Journal of neuroengineering and rehabilitation
pub_type: 杂志文章
doi:10.1186/s12984-019-0564-2
更新日期:2019-07-25 00:00:00
abstract:BACKGROUND:Epidural stimulation of the spinal cord can be used to enable stepping on a treadmill (electrical enabling motor control, eEmc) after a complete mid-thoracic spinal cord transection in adult rats. Herein we have studied the effects of eEmc using a sub-threshold intensity of stimulation combined with spontane...
journal_title:Journal of neuroengineering and rehabilitation
pub_type: 杂志文章
doi:10.1186/1743-0003-10-108
更新日期:2013-10-24 00:00:00
abstract:BACKGROUND:KINARM end point robotic testing on a range of tasks evaluating sensory, motor and cognitive function in children/adolescents with no neurologic impairment has been shown to be reliable. The objective of this study was to determine whether differences in baseline performance on multiple robotic tasks could b...
journal_title:Journal of neuroengineering and rehabilitation
pub_type: 杂志文章
doi:10.1186/s12984-016-0195-9
更新日期:2016-10-12 00:00:00
abstract:BACKGROUND:Steady-state visually evoked potentials (SSVEPs) can be elicited by repetitive stimuli and extracted in the frequency domain with satisfied performance. However, the temporal information of such stimulus is often ignored. In this study, we utilized repetitive visual stimuli with missing events to present a n...
journal_title:Journal of neuroengineering and rehabilitation
pub_type: 杂志文章
doi:10.1186/s12984-016-0179-9
更新日期:2016-07-26 00:00:00
abstract:BACKGROUND:The purpose of this study was to investigate the biomechanics of the hip, knee and ankle during a progressive resistance cycling protocol in an effort to detect and measure the presence of muscle fatigue. It was hypothesized that knee power output can be used as an indicator of fatigue in order to assess the...
journal_title:Journal of neuroengineering and rehabilitation
pub_type: 杂志文章
doi:10.1186/1743-0003-5-14
更新日期:2008-04-26 00:00:00
abstract::The purpose of this study was to longitudinally compare the sensitivity of previously documented paradigms for measuring balance control during gait following a concussion. We hypothesized that gait with a concurrent cognitive task would be most sensitive to the effects of concussion on dynamic balance control. Indivi...
journal_title:Journal of neuroengineering and rehabilitation
pub_type: 杂志文章
doi:10.1186/1743-0003-6-25
更新日期:2009-07-07 00:00:00
abstract:BACKGROUND:Obesity is a major problem especially in western countries and several studies underline the importance of physical activity to enhance diet. Currently there is increasing interest in instruments for monitoring daily physical activity. The purpose of this pilot study was to appraise the qualitative and quant...
journal_title:Journal of neuroengineering and rehabilitation
pub_type: 杂志文章
doi:10.1186/1743-0003-6-47
更新日期:2009-12-30 00:00:00
abstract:BACKGROUND:Previous reports of the mechanics and energetics of post-stroke hemiparetic walking have either not combined estimates of mechanical and metabolic energy or computed external mechanical work based on the limited combined limbs method. Here we present a comparison of the mechanics and energetics of hemipareti...
journal_title:Journal of neuroengineering and rehabilitation
pub_type: 杂志文章
doi:10.1186/s12984-015-0012-x
更新日期:2015-02-27 00:00:00
abstract:BACKGROUND:Patient-specific performance assessment of arm movements in daily life activities is fundamental for neurological rehabilitation therapy. In most applications, the shoulder movement is simplified through a socket-ball joint, neglecting the movement of the scapular-thoracic complex. This may lead to significa...
journal_title:Journal of neuroengineering and rehabilitation
pub_type: 杂志文章
doi:10.1186/s12984-016-0149-2
更新日期:2016-04-23 00:00:00
abstract:BACKGROUND:Robot-based rehabilitation for persons post-stroke may improve arm function and daily-life activities as measured by clinical scales, but its effects on motor strategies during functional tasks are still poorly investigated. This study aimed at assessing the effects of robot-therapy versus arm-specific physi...
journal_title:Journal of neuroengineering and rehabilitation
pub_type: 杂志文章,随机对照试验
doi:10.1186/s12984-020-0646-1
更新日期:2020-01-30 00:00:00
abstract:BACKGROUND:A proper rehabilitation program targeting gait is mandatory to maintain the quality of life of patients with Myotonic dystrophy type 1 (DM1). Assuming that gait and balance impairment simply depend on the degree of muscle weakness is potentially misleading. In fact, the involvement of the Central Nervous Sys...
journal_title:Journal of neuroengineering and rehabilitation
pub_type: 杂志文章
doi:10.1186/s12984-019-0590-0
更新日期:2019-09-18 00:00:00
abstract:BACKGROUND:To improve gait, persons with calf muscle weakness can be provided with a dorsal leaf spring ankle foot orthosis (DLS-AFO). These AFOs can store energy during stance and return this energy during push-off, which, in turn, reduces walking energy cost. Simulations indicate that the effect of the DLS-AFO on wal...
journal_title:Journal of neuroengineering and rehabilitation
pub_type: 临床试验,杂志文章
doi:10.1186/s12984-019-0600-2
更新日期:2019-10-17 00:00:00
abstract:BACKGROUND:Following an amputation, the human postural control system develops neuromuscular adaptations to regain an effective postural control. We investigated the compensatory mechanisms behind these adaptations and how sensorimotor integration is affected after a lower-limb transfemoral amputation. METHODS:Center ...
journal_title:Journal of neuroengineering and rehabilitation
pub_type: 杂志文章
doi:10.1186/s12984-019-0586-9
更新日期:2019-09-14 00:00:00
abstract:BACKGROUND:Although some gait parameters from inertial sensors have been shown to be associated with important clinical issues, because of controversial results, it remains uncertain which parameters for which axes are clinically valuable. Following the idea that a comprehensive score obtained by summing various gait p...
journal_title:Journal of neuroengineering and rehabilitation
pub_type: 杂志文章
doi:10.1186/s12984-019-0539-3
更新日期:2019-05-28 00:00:00
abstract::The general objective of the "Rehabilitation Medicine Summit: Building Research Capacity" was to advance and promote research in medical rehabilitation by making recommendations to expand research capacity. The five elements of research capacity that guided the discussions were: 1) researchers; 2) research culture, en...
journal_title:Journal of neuroengineering and rehabilitation
pub_type: 杂志文章
doi:10.1186/1743-0003-3-1
更新日期:2006-01-03 00:00:00
abstract:BACKGROUND:Functional Electrical Stimulation (FES) cycling can benefit health and may lead to neuroplastic changes following incomplete spinal cord injury (SCI). Our theory is that greater neurological recovery occurs when electrical stimulation of peripheral nerves is combined with voluntary effort. In this pilot stud...
journal_title:Journal of neuroengineering and rehabilitation
pub_type: 临床试验,杂志文章
doi:10.1186/s12984-019-0619-4
更新日期:2019-11-27 00:00:00
abstract:BACKGROUND:Recent studies have shown that neural stimulation can be used to provide artificial sensory feedback to amputees eliciting sensations referred on the amputated hand. The temporal properties of the neural stimulation modulate aspects of evoked sensations that can be exploited in a bidirectional hand prosthesi...
journal_title:Journal of neuroengineering and rehabilitation
pub_type: 杂志文章
doi:10.1186/s12984-020-00737-8
更新日期:2020-08-15 00:00:00
abstract:BACKGROUND:Loss of hand function following high level spinal cord injury (SCI) is perceived as a high priority area for rehabilitation. Following discharge, it is often impractical for the specialist care centre to provide ongoing therapy for people living with chronic SCI at home, which can lead to further deteriorati...
journal_title:Journal of neuroengineering and rehabilitation
pub_type: 临床试验,杂志文章
doi:10.1186/s12984-020-00660-y
更新日期:2020-03-05 00:00:00
abstract:BACKGROUND:A complete spinal cord transection results in loss of all supraspinal motor control below the level of the injury. The neural circuitry in the lumbosacral spinal cord, however, can generate locomotor patterns in the hindlimbs of rats and cats with the aid of motor training, epidural stimulation and/or admini...
journal_title:Journal of neuroengineering and rehabilitation
pub_type: 杂志文章
doi:10.1186/1743-0003-9-38
更新日期:2012-06-12 00:00:00
abstract:BACKGROUND:Robotic technologies for neurological assessment provide sensitive, objective measures of behavioural impairments associated with injuries or disease such as stroke. Previous robotic tasks to assess proprioception typically involve single limbs or in some cases both limbs. The challenge with these approaches...
journal_title:Journal of neuroengineering and rehabilitation
pub_type: 杂志文章
doi:10.1186/s12984-020-00721-2
更新日期:2020-07-25 00:00:00
abstract:BACKGROUND:Electrooculogram (EOG) can be used to continuously track eye movements and can thus be considered as an alternative to conventional camera-based eye trackers. Although many EOG-based eye tracking systems have been studied with the ultimate goal of providing a new way of communication for individuals with amy...
journal_title:Journal of neuroengineering and rehabilitation
pub_type: 杂志文章
doi:10.1186/s12984-017-0303-5
更新日期:2017-09-08 00:00:00
abstract:BACKGROUND:The restoration of walking ability is the main goal of post-stroke lower limb rehabilitation and different studies suggest that pedaling may have a positive effect on locomotion. The aim of this study was to explore the feasibility of a biofeedback pedaling treatment and its effects on cycling and walking ab...
journal_title:Journal of neuroengineering and rehabilitation
pub_type: 临床试验,杂志文章
doi:10.1186/1743-0003-8-47
更新日期:2011-08-24 00:00:00
abstract:BACKGROUND:Muscle synergies are now widely discussed as a method for evaluating the existence of redundant neural networks that can be activated to enhance stroke rehabilitation. However, this approach was initially conceived to study muscle coordination during learned motions in healthy individuals. After brain damage...
journal_title:Journal of neuroengineering and rehabilitation
pub_type: 杂志文章
doi:10.1186/s12984-019-0611-z
更新日期:2019-11-04 00:00:00
abstract:BACKGROUND:Treadmill training, with or without body-weight support (BWSTT), typically involves high step count, faster walking speed, and higher heart-rate intensity than overground walking training. The addition of challenging mobility skill practice may offer increased opportunities to improve walking and balance ski...
journal_title:Journal of neuroengineering and rehabilitation
pub_type: 杂志文章,随机对照试验
doi:10.1186/s12984-018-0442-3
更新日期:2018-11-01 00:00:00
abstract:BACKGROUND:People with a lower-extremity amputation that use conventional passive-elastic ankle-foot prostheses encounter a series of stress-related challenges during walking such as greater forces on their unaffected leg, and may thus be predisposed to secondary musculoskeletal injuries such as chronic joint disorders...
journal_title:Journal of neuroengineering and rehabilitation
pub_type: 杂志文章
doi:10.1186/1743-0003-10-49
更新日期:2013-06-07 00:00:00
abstract:BACKGROUND:Task-specific perturbation training is a widely studied means of fall prevention, utilizing techniques that induce slips or slip-like perturbations during gait. Though effective, these methods only simulate narrow ranges within the larger space of possible slipping conditions encountered in daily life. Here ...
journal_title:Journal of neuroengineering and rehabilitation
pub_type: 杂志文章
doi:10.1186/s12984-019-0602-0
更新日期:2019-10-17 00:00:00