Abstract:
BACKGROUND:Robot-based rehabilitation for persons post-stroke may improve arm function and daily-life activities as measured by clinical scales, but its effects on motor strategies during functional tasks are still poorly investigated. This study aimed at assessing the effects of robot-therapy versus arm-specific physiotherapy in persons post-stroke on motor strategies derived from upper body instrumented kinematic analysis, and on arm function measured by clinical scales. METHODS:Forty persons in the sub-acute and chronic stage post-stroke were recruited. This sample included all those subjects, enrolled in a larger bi-center study, who underwent instrumented kinematic analysis and who were randomized in Center 2 into Robot (R_Group) and Control Group (C_Group). R_Group received robot-assisted training. C_Group received arm-specific treatment delivered by a physiotherapist. Pre- and post-training assessment included clinical scales and instrumented kinematic analysis of arm and trunk during a virtual untrained task simulating the transport of an object onto a shelf. Instrumented outcomes included shoulder/elbow coordination, elbow extension and trunk sagittal compensation. Clinical outcomes included Fugl-Meyer Motor Assessment of Upper Extremity (FM-UE), modified Ashworth Scale (MAS) and Functional Independence Measure (FIM). RESULTS:R_Group showed larger post-training improvements of shoulder/elbow coordination (Cohen's d = - 0.81, p = 0.019), elbow extension (Cohen's d = - 0.71, p = 0.038), and trunk movement (Cohen's d = - 1.12, p = 0.002). Both groups showed comparable improvements in clinical scales, except proximal muscles MAS that decreased more in R_Group (Cohen's d = - 0.83, p = 0.018). Ancillary analyses on chronic subjects confirmed these results and revealed larger improvements after robot-therapy in the proximal portion of FM-UE (Cohen's d = 1.16, p = 0.019). CONCLUSIONS:Robot-assisted rehabilitation was as effective as arm-specific physiotherapy in reducing arm impairment (FM-UE) in persons post-stroke, but it was more effective in improving motor control strategies adopted during an untrained task involving vertical movements not practiced during training. Specifically, robot therapy induced larger improvements of shoulder/elbow coordination and greater reduction of abnormal trunk sagittal movements. The beneficial effects of robot therapy seemed more pronounced in chronic subjects. Future studies on a larger sample should be performed to corroborate present findings. TRIAL REGISTRATION:www.ClinicalTrials.gov NCT03530358. Registered 21 May 2018. Retrospectively registered.
journal_name
J Neuroeng Rehabiljournal_title
Journal of neuroengineering and rehabilitationauthors
Carpinella I,Lencioni T,Bowman T,Bertoni R,Turolla A,Ferrarin M,Jonsdottir Jdoi
10.1186/s12984-020-0646-1subject
Has Abstractpub_date
2020-01-30 00:00:00pages
10issue
1issn
1743-0003pii
10.1186/s12984-020-0646-1journal_volume
17pub_type
杂志文章,随机对照试验abstract:BACKGROUND:Virtual reality (VR) is not commonly used in clinical rehabilitation, and commercial VR gaming systems may have mixed effects in patients with stroke. Therefore, we developed RehabMaster™, a task-specific interactive game-based VR system for post-stroke rehabilitation of the upper extremities, and assessed i...
journal_title:Journal of neuroengineering and rehabilitation
pub_type: 杂志文章,随机对照试验
doi:10.1186/1743-0003-11-32
更新日期:2014-03-06 00:00:00
abstract:BACKGROUND:Multiple sclerosis (MS) is a disabling disease affecting the central nervous system and consequently the whole body's functional systems resulting in different gait disorders. Fatigue is the most common symptom in MS with a prevalence of 80%. Previous research studied the relation between fatigue and gait im...
journal_title:Journal of neuroengineering and rehabilitation
pub_type: 杂志文章
doi:10.1186/s12984-020-00798-9
更新日期:2020-12-18 00:00:00
abstract::The original article [1] contained an error whereby Fig. 6 contained a minor shading glitch affecting its presentation. This has now been corrected. ...
journal_title:Journal of neuroengineering and rehabilitation
pub_type: 已发布勘误
doi:10.1186/s12984-019-0567-z
更新日期:2019-07-26 00:00:00
abstract:BACKGROUND:Functional electrical stimulation (FES) has been used to improve function in individuals with hemiparesis following stroke. An ideal functional electrical stimulation (FES) system needs an accurate mathematical model capable of designing subject and task-specific stimulation patterns. Such a model was previo...
journal_title:Journal of neuroengineering and rehabilitation
pub_type: 杂志文章
doi:10.1186/1743-0003-5-7
更新日期:2008-02-27 00:00:00
abstract:BACKGROUND:Vibrotactile stimulation is a promising venue in the field of prosthetics to retrain sensory feedback deficits following amputation. Discrimination is well established at the forearm level but not at the upper arm level. Moreover, the effects of combining vibration characteristics such as duration and intens...
journal_title:Journal of neuroengineering and rehabilitation
pub_type: 杂志文章
doi:10.1186/s12984-019-0597-6
更新日期:2019-11-13 00:00:00
abstract::Unfortunately, the original version of this article [1] contained an error. Equation 6 was included incorrectly: in the original equation variable slinks3 was missing.The correct Equation 6 can be found below: ...
journal_title:Journal of neuroengineering and rehabilitation
pub_type: 已发布勘误
doi:10.1186/s12984-015-0106-5
更新日期:2015-12-04 00:00:00
abstract:BACKGROUND:To go from one place to another, we routinely generate internal representations of surrounding spaces, which can include egocentric (body-centred) and allocentric (world-centred) coordinates, combined into route and survey representations.Recent studies have shown how both egocentric and allocentric represen...
journal_title:Journal of neuroengineering and rehabilitation
pub_type: 杂志文章
doi:10.1186/1743-0003-8-6
更新日期:2011-01-31 00:00:00
abstract:BACKGROUND:There is an increasing trend in using robots for medical purposes. One specific area is rehabilitation. Rehabilitation is one of the non-drug treatments in community health which means the restoration of the abilities to maximize independence. It is a prolonged work and costly labor. On the other hand, by us...
journal_title:Journal of neuroengineering and rehabilitation
pub_type: 杂志文章
doi:10.1186/1743-0003-10-96
更新日期:2013-08-14 00:00:00
abstract:BACKGROUND:Textile-based transducers are an emerging technology in which piezo-resistive properties of materials are used to measure an applied strain. By incorporating these sensors into a sock, this technology offers the potential to detect critical events during the stance phase of the gait cycle. This could prove u...
journal_title:Journal of neuroengineering and rehabilitation
pub_type: 杂志文章
doi:10.1186/1743-0003-8-32
更新日期:2011-05-27 00:00:00
abstract:BACKGROUND:Elastic ankle exoskeletons with intermediate stiffness springs in parallel with the human plantarflexors can reduce the metabolic cost of walking by ~ 7% at 1.25 m s- 1. In a move toward 'real-world' application, we examined whether the unpowered approach has metabolic benefit across a range of walking speed...
journal_title:Journal of neuroengineering and rehabilitation
pub_type: 杂志文章
doi:10.1186/s12984-020-00703-4
更新日期:2020-06-15 00:00:00
abstract:BACKGROUND:Treadmill training with bodyweight support and manual assistance improves walking ability of patients with neurological injury. The purpose of this study was to determine how manual assistance changes muscle activation and kinematic patterns during treadmill training in individuals with incomplete spinal cor...
journal_title:Journal of neuroengineering and rehabilitation
pub_type: 临床试验,杂志文章
doi:10.1186/1743-0003-4-32
更新日期:2007-08-21 00:00:00
abstract:BACKGROUND:Compensatory movements are commonly employed by stroke survivors during seated reaching and may have negative effects on their long-term recovery. Detecting compensation is useful for coaching the patient to reduce compensatory trunk movements and improving the motor function of the paretic arm. Sensor-based...
journal_title:Journal of neuroengineering and rehabilitation
pub_type: 杂志文章
doi:10.1186/s12984-019-0609-6
更新日期:2019-11-04 00:00:00
abstract:BACKGROUND:Functional near infrared spectroscopy (fNIRS) finds extended applications in a variety of neuroscience fields. We investigated the potential of fNIRS to monitor voluntary engagement of users during neurorehabilitation, especially during combinatory exercise (CE) that simultaneously uses both, passive and act...
journal_title:Journal of neuroengineering and rehabilitation
pub_type: 杂志文章
doi:10.1186/s12984-018-0365-z
更新日期:2018-03-23 00:00:00
abstract:BACKGROUND:Postural control requires numerous inputs interacting across multiple temporospatial scales. This organization, evidenced by the "complexity" contained within standing postural sway fluctuations, enables diverse system functionality. Age-related reduction of foot-sole somatosensation reduces standing postura...
journal_title:Journal of neuroengineering and rehabilitation
pub_type: 杂志文章
doi:10.1186/s12984-016-0152-7
更新日期:2016-05-03 00:00:00
abstract:BACKGROUND:Cerebellar symptoms are extremely disabling and are common in Multiple Sclerosis (MS) subjects. In this feasibility study, we developed and tested a robot therapy protocol, aimed at the rehabilitation of incoordination in MS subjects. METHODS:Eight subjects with clinically defined MS performed planar reachi...
journal_title:Journal of neuroengineering and rehabilitation
pub_type: 杂志文章,随机对照试验
doi:10.1186/1743-0003-7-37
更新日期:2010-07-29 00:00:00
abstract:BACKGROUND:Rehabilitation robotics is progressing towards developing robots that can be used as advanced tools to augment the role of a therapist. These robots are capable of not only offering more frequent and more accessible therapies but also providing new insights into treatment effectiveness based on their ability...
journal_title:Journal of neuroengineering and rehabilitation
pub_type: 杂志文章
doi:10.1186/1743-0003-10-102
更新日期:2013-09-28 00:00:00
abstract:OBJECTIVE:To study the effects of reduced lighting on the gait of older adults with a high level gait disorder (HLGD) and to compare their response to that of healthy elderly controls. METHODS:22 patients with a HLGD and 20 age-matched healthy controls were studied under usual lighting conditions (1000 lumens) and in ...
journal_title:Journal of neuroengineering and rehabilitation
pub_type: 杂志文章
doi:10.1186/1743-0003-2-27
更新日期:2005-08-28 00:00:00
abstract:BACKGROUND:Lower motor neurons in the spinal cord lose supraspinal inputs after complete spinal cord injury, leading to a loss of volitional control below the injury site. Extensive locomotor training with spinal cord stimulation can restore locomotion function after spinal cord injury in humans and animals. However, t...
journal_title:Journal of neuroengineering and rehabilitation
pub_type: 杂志文章
doi:10.1186/1743-0003-11-107
更新日期:2014-07-03 00:00:00
abstract:BACKGROUND:Task-specific perturbation training is a widely studied means of fall prevention, utilizing techniques that induce slips or slip-like perturbations during gait. Though effective, these methods only simulate narrow ranges within the larger space of possible slipping conditions encountered in daily life. Here ...
journal_title:Journal of neuroengineering and rehabilitation
pub_type: 杂志文章
doi:10.1186/s12984-019-0602-0
更新日期:2019-10-17 00:00:00
abstract:BACKGROUND:Deep brain stimulation (DBS) in the subthalamic nucleus (STN) significantly reduces symptoms of Parkinson's disease (PD) such as bradykinesia, tremor and rigidity. It also reduces the need for anti-PD medication, and thereby potential side-effects of L-Dopa. Although DBS in the STN is a highly effective ther...
journal_title:Journal of neuroengineering and rehabilitation
pub_type: 杂志文章
doi:10.1186/1743-0003-10-33
更新日期:2013-04-03 00:00:00
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journal_title:Journal of neuroengineering and rehabilitation
pub_type: 杂志文章,评审
doi:10.1186/1743-0003-9-20
更新日期:2012-04-20 00:00:00
abstract:BACKGROUND:Support for rehabilitation research at the National Institutes of Health (NIH) is robust and evolving. Since the time of its Blue Ribbon Panel on Rehabilitation Research, NIH has participated in several initiatives to coordinate the science and advance the field. DISCUSSION:Collaborative teams must continue...
journal_title:Journal of neuroengineering and rehabilitation
pub_type: 信件
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更新日期:2020-05-29 00:00:00
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journal_title:Journal of neuroengineering and rehabilitation
pub_type: 临床试验,杂志文章
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更新日期:2019-11-27 00:00:00
abstract:BACKGROUND:There is a paucity of information regarding visuospatial (VS) and visuomotor (VM) task performance in patients with chronic right fronto-parietal lobe stroke, as the majority of knowledge to date in this realm has been gleaned from acute stroke patients. The goal of this paper is to determine how VS and VM p...
journal_title:Journal of neuroengineering and rehabilitation
pub_type: 杂志文章
doi:10.1186/1743-0003-10-20
更新日期:2013-02-13 00:00:00
abstract:BACKGROUND:Locomotor strategies for obstacle circumvention require appropriate postural coordination that depends on sensorimotor integration within the central nervous system. It is not known how these strategies are affected by a stroke. The objective of this study was to contrast postural coordination strategies use...
journal_title:Journal of neuroengineering and rehabilitation
pub_type: 杂志文章
doi:10.1186/s12984-017-0265-7
更新日期:2017-06-15 00:00:00
abstract:BACKGROUND:Since physical activity and exercise levels are known to be generally low in persons with spinal cord injury (SCI), there seems to be a need for intervention. Exercise self-efficacy (ESE), the confidence persons have in their ability to be physically active and exercise, is an important and modifiable predic...
journal_title:Journal of neuroengineering and rehabilitation
pub_type: 杂志文章
doi:10.1186/s12984-015-0099-0
更新日期:2015-11-19 00:00:00
abstract:BACKGROUND:Individuals with severe neurological disabilities but preserved cognition, including children, are often precluded from connecting with their environments. Brain computer interfaces (BCI) are a potential solution where advancing technologies create new clinical opportunities. We evaluated clinician awareness...
journal_title:Journal of neuroengineering and rehabilitation
pub_type: 杂志文章
doi:10.1186/s12984-019-0624-7
更新日期:2020-01-06 00:00:00
abstract:BACKGROUND:Walking deficits in people post-stroke are often multiple and idiosyncratic in nature. Limited patient and therapist resources necessitate prioritization of deficits such that some may be left unaddressed. More efficient delivery of therapy may alleviate this challenge. Here, we look to determine the utility...
journal_title:Journal of neuroengineering and rehabilitation
pub_type: 杂志文章
doi:10.1186/s12984-019-0635-4
更新日期:2019-12-23 00:00:00
abstract::The original use of biofeedback to train single muscle activity in static positions or movement unrelated to function did not correlate well to motor function improvements in patients with central nervous system injuries. The concept of task-oriented repetitive training suggests that biofeedback therapy should be deli...
journal_title:Journal of neuroengineering and rehabilitation
pub_type: 杂志文章
doi:10.1186/1743-0003-3-11
更新日期:2006-06-21 00:00:00
abstract:BACKGROUND:Wrist movement-related injuries account for a large number of repetitive motion injuries. Remarkably little, if any, empirical data exist to quantify the impact of neuromuscular disorders affecting the wrist or to validate the effectiveness of rehabilitation training programs on wrist functions. The aim of t...
journal_title:Journal of neuroengineering and rehabilitation
pub_type: 杂志文章
doi:10.1186/1743-0003-11-157
更新日期:2014-11-17 00:00:00