Biotech and biomaterials research to reduce the caries epidemic.

Abstract:

:The goal of this workshop is to develop a consensus within the biomaterials/bioengineering community for a research agenda focused on creating technologies that will address the current dental caries pandemic. The workshop will bring together expertise from academia, industry, and the NIH institutes in the areas of oral biofilm microbiology and innovative biomaterials. The rationale for the workshop is that science and technology have not produced sufficient practical tools for public health practitioners and the private delivery system to address the pandemic in dental caries that exists for children and adults from families with low incomes and for numerous ethnic minority and racial groups. Moreover, it is unclear whether the barriers are remediable bioengineering and technical problems or fundamental science questions. Nevertheless, the obligation to address the gap between scientific research and practical application is especially relevant today. The U.S. and state governments bear the majority of the cost of trying to control this pandemic through Medicaid, the Public Health Service, Indian Health Service and other similar programs. These costs continue to escalate as continued applications of existing technology are unlikely to markedly reduce disparities. The mainstays of caries prevention, topical and systemic fluorides and pit and fissure sealants, are technologies developed in the 1950s and 1960s.

journal_name

BMC Oral Health

journal_title

BMC oral health

authors

Slayton RL,Bryers JD,Milgrom P

doi

10.1186/1472-6831-6-S1-S1

subject

Has Abstract

pub_date

2006-06-15 00:00:00

pages

S1

issn

1472-6831

pii

1472-6831-6-S1-S1

journal_volume

6 Suppl 1

pub_type

杂志文章
  • Prevalence and socio-behavioral influence of early childhood caries, ECC, and feeding habits among 6-36 months old children in Uganda and Tanzania.

    abstract:BACKGROUND:Early childhood caries (ECC) is a serious problem that has remained unexplored in sub-Saharan Africa. This study aimed to identify possible socio-behavioral correlates of ECC focusing 6-36 months old children and their caretakers. METHODS:Cross sectional studies were conducted in a high fluoride rural area,...

    journal_title:BMC oral health

    pub_type: 杂志文章

    doi:10.1186/1472-6831-12-24

    authors: Masumo R,Bardsen A,Mashoto K,Åstrøm AN

    更新日期:2012-07-26 00:00:00

  • Managing dental caries in children in Turkey--a discussion paper.

    abstract:BACKGROUND:This paper describes the oral healthcare system and disease situation amongst children in Turkey. Considering the high prevalence and severity of dental caries, a proposal for improvement of oral health in this population group is formulated. DISCUSSION:A virtual absence of palliative, preventive and restor...

    journal_title:BMC oral health

    pub_type: 杂志文章

    doi:10.1186/1472-6831-9-32

    authors: Topaloglu-Ak A,Eden E,Frencken JE

    更新日期:2009-11-25 00:00:00

  • Effect of mouthrinses on color stability of monolithic zirconia and feldspathic ceramic: an in vitro study.

    abstract:BACKGROUND:Patients susceptible to periodontal disease and dental caries, including those who undergo fixed prosthodontic treatments use chemical plaque control agents. However, these mouthrinses may result in adverse effects such as discoloration of the restorative materials. The aim of this study was to compare the c...

    journal_title:BMC oral health

    pub_type: 杂志文章

    doi:10.1186/s12903-017-0419-9

    authors: Derafshi R,Khorshidi H,Kalantari M,Ghaffarlou I

    更新日期:2017-11-07 00:00:00

  • A surrogate method for comparison analysis of salivary concentrations of Xylitol-containing products.

    abstract:BACKGROUND:Xylitol chewing gum has been shown to reduce Streptococcus mutans levels and decay. Two studies examined the presence and time course of salivary xylitol concentrations delivered via xylitol-containing pellet gum and compared them to other xylitol-containing products. METHODS:A within-subjects design was us...

    journal_title:BMC oral health

    pub_type: 杂志文章

    doi:10.1186/1472-6831-8-5

    authors: Riedy CA,Milgrom P,Ly KA,Rothen M,Mueller G,Hagstrom MK,Tolentino E,Zhou L,Roberts MC

    更新日期:2008-02-11 00:00:00

  • Risk indicators for severe impaired oral health among indigenous Australian young adults.

    abstract:BACKGROUND:Oral health impairment comprises three conceptual domains; pain, appearance and function. This study sought to: (1) estimate the prevalence of severe oral health impairment as assessed by a summary oral health impairment measure, including aspects of dental pain, dissatisfaction with dental appearance and di...

    journal_title:BMC oral health

    pub_type: 杂志文章

    doi:10.1186/1472-6831-10-1

    authors: Jamieson LM,Roberts-Thomson KF,Sayers SM

    更新日期:2010-01-27 00:00:00

  • A new method for assessment of nickel-titanium endodontic instrument surface roughness using field emission scanning electronic microscope.

    abstract:BACKGROUND:To introduce a new method for measurement of surface roughness of the endodontic instrument, before and after instrumentation, using the Field Emission Scanning Electronic Microscope (FE-SEM) combined with the ImageJ software. METHODS:Twenty J-shape resin blocks were divided into two groups, ten blocks of e...

    journal_title:BMC oral health

    pub_type: 杂志文章

    doi:10.1186/s12903-020-01233-0

    authors: Van Pham K,Vo CQ

    更新日期:2020-08-31 00:00:00

  • Oral and maxillofacial surgery in patients undergoing dialysis for advanced renal disease: report of five cases.

    abstract:BACKGROUND:Perioperativemanagement of hemodialysis patients involves many difficulties. High mortality rate and circulatory or respiratory complications in these patients were reported. However, in such reports, there is no concrete information of perioperative management in hemodialysis patients to prevent surgical co...

    journal_title:BMC oral health

    pub_type: 杂志文章

    doi:10.1186/s12903-018-0634-z

    authors: Mochizuki Y,Harada H,Yokokawa M,Kinoshita N,Kubota K,Okado T,Fukayama H

    更新日期:2018-10-19 00:00:00

  • Overexpression of Epstein-Barr virus-encoded latent membrane protein-1 (LMP-1) in oral squamous cell carcinoma.

    abstract:BACKGROUND:As oral cavity is the main location of Epstein-Barr virus (EBV) latency and shedding, and as EBV-encoded latent membrane protein-1 (LMP-1) has a crucial role in cell transformation, association between EBV infection, LMP-1 expression and oral malignancy is of interest. Although EBV DNA has been detected in o...

    journal_title:BMC oral health

    pub_type: 杂志文章

    doi:10.1186/s12903-019-0832-3

    authors: Rahman R,Poomsawat S,Juengsomjit R,Buajeeb W

    更新日期:2019-07-10 00:00:00

  • Efficacy of citric acid denture cleanser on the Candida albicans biofilm formed on poly(methyl methacrylate): effects on residual biofilm and recolonization process.

    abstract:BACKGROUND:It is well known that the use of denture cleansers can reduce Candida albicans biofilm accumulation; however, the efficacy of citric acid denture cleansers is uncertain. In addition, the long-term efficacy of this denture cleanser is not well established, and their effect on residual biofilms is unknown. Thi...

    journal_title:BMC oral health

    pub_type: 杂志文章

    doi:10.1186/1472-6831-14-77

    authors: Faot F,Cavalcanti YW,Mendonça e Bertolini Md,Pinto Lde R,da Silva WJ,Cury AA

    更新日期:2014-06-23 00:00:00

  • Validation of the Turkish version of the Liverpool Oral Rehabilitation Questionnaire version 3 (LORQv3) in prosthetically rehabilitated patients with head and neck cancer.

    abstract:BACKGROUND:The Liverpool Oral Rehabilitation Questionnaire version 3 (LORQv3) is a measure assessing the impact of oral rehabilitation on patients' health-related quality of life (HRQOL).The aims of the study were to adapt culturally the LORQv3 for Turkish-speaking head and neck cancer patients who had undergone prosth...

    journal_title:BMC oral health

    pub_type: 杂志文章

    doi:10.1186/1472-6831-14-129

    authors: Peker K,Ozdemir-Karatas M,Balık A,Kürklü E,Uysal O,Rogers SN

    更新日期:2014-10-22 00:00:00

  • Contextual and individual assessment of dental pain period prevalence in adolescents: a multilevel approach.

    abstract:BACKGROUND:Despite evidence that health and disease occur in social contexts, the vast majority of studies addressing dental pain exclusively assessed information gathered at individual level. OBJECTIVES:To assess the association between dental pain and contextual and individual characteristics in Brazilian adolescent...

    journal_title:BMC oral health

    pub_type: 杂志文章

    doi:10.1186/1472-6831-10-20

    authors: Peres MA,Peres KG,Frias AC,Antunes JL

    更新日期:2010-08-13 00:00:00

  • Factors affecting the early failure of implants placed in a dental practice with a specialization in implantology - a retrospective study.

    abstract:BACKGROUND:To evaluate early failure and possible risk factors for failure of dental implants placed under practice-based conditions. METHODS:To clarify the research question, anonymized data from 106 patients with 186 dental implants were analyzed. The presence of sucessful healing (yes/no) at the time of incorporati...

    journal_title:BMC oral health

    pub_type: 杂志文章

    doi:10.1186/s12903-019-0900-8

    authors: Krisam J,Ott L,Schmitz S,Klotz AL,Seyidaliyeva A,Rammelsberg P,Zenthöfer A

    更新日期:2019-09-05 00:00:00

  • Surface electromyography pattern of human swallowing.

    abstract:BACKGROUND:The physiology of swallowing is characterized by a complex and coordinated activation of many stomatognathic, pharyngeal, and laryngeal muscles. Kinetics and electromyographic studies have widely investigated the pharyngeal and laryngeal pattern of deglutition in order to point out the differences between no...

    journal_title:BMC oral health

    pub_type: 杂志文章

    doi:10.1186/1472-6831-8-6

    authors: Monaco A,Cattaneo R,Spadaro A,Giannoni M

    更新日期:2008-03-26 00:00:00

  • Effect of different doses of radiation on morphogical, mechanical and chemical properties of primary and permanent teeth-an in vitro study.

    abstract:BACKGROUND:Radiotherapy, applied to the head and neck region, can cause radiation side effects such as reduction of saliva and radiation caries. The aim of this study was to perform an in vitro assessment of the effects of radiation therapy on the morphological, mechanical, and chemical properties of primary and perman...

    journal_title:BMC oral health

    pub_type: 杂志文章

    doi:10.1186/s12903-020-01222-3

    authors: Duruk G,Acar B,Temelli Ö

    更新日期:2020-09-01 00:00:00

  • Knowledge, attitude and compliance of infection control guidelines among dental faculty members and students in KSU.

    abstract:BACKGROUND:Infection is one of the most crucial problems in health care services worldwide. It is considered one of the most important causes of morbidity and mortality associated with clinical, diagnostic and therapeutic procedures. Therefore, the purpose of this study was to investigate knowledge, attitude, and compl...

    journal_title:BMC oral health

    pub_type: 杂志文章

    doi:10.1186/s12903-018-0706-0

    authors: Alharbi G,Shono N,Alballaa L,Aloufi A

    更新日期:2019-01-09 00:00:00

  • Weight, height and eruption times of permanent teeth of children aged 4-15 years in Kampala, Uganda.

    abstract:BACKGROUND:Tooth eruption is a continuous biological process by which developing teeth emerge through the jaws and the overlying mucosa to enter into the oral cavity. Tooth eruption time and sequence are important factors in dental treatment planning, particularly in orthodontics, but also in forensic dentistry to esti...

    journal_title:BMC oral health

    pub_type: 杂志文章

    doi:10.1186/1472-6831-13-15

    authors: Kutesa A,Nkamba EM,Muwazi L,Buwembo W,Rwenyonyi CM

    更新日期:2013-03-16 00:00:00

  • Psychometric characteristics of the "General Oral Health Assessment Index (GOHAI) » in a French representative sample of patients with schizophrenia.

    abstract:BACKGROUND:The "General Oral Health Assessment Index" (GOHAI) was widely used in clinical or epidemiological studies worldwide, as it was available for use in different languages. Therefore, the aim of this study was to evaluate the psychometric characteristics of the GOHAI in a representative sample of patients with s...

    journal_title:BMC oral health

    pub_type: 杂志文章

    doi:10.1186/s12903-017-0368-3

    authors: Denis F,Hamad M,Trojak B,Tubert-Jeannin S,Rat C,Pelletier JF,Rude N

    更新日期:2017-04-11 00:00:00

  • Comparative evaluation of volumetric changes of three different retrograde calcium silicate materials placed under different pH condititions.

    abstract:BACKGROUND:The present study aimed to compare the volumetric changes of three calcium silicate cements after retrofilling and placing under different pH conditions via micro-computed tomography (micro-CT) scan. METHODS:Forty-two extracted human single-rooted teeth were randomly assigned to three groups according to th...

    journal_title:BMC oral health

    pub_type: 杂志文章

    doi:10.1186/s12903-020-01325-x

    authors: Kwon SY,Seo MS

    更新日期:2020-11-19 00:00:00

  • Does post-bleaching fluoridation affect the further demineralization of bleached enamel? An in vitro study.

    abstract:BACKGROUND:Topical fluoride agents have been shown to be the most effective method in treating demineralized enamel after in-office bleaching treatments. Thus, this study aimed to examine the effects of two different post-bleaching fluoridation agents: 1.5% titanium tetrafluoride (TiF(4)) (9200 ppm) and 2.1% sodium flu...

    journal_title:BMC oral health

    pub_type: 杂志文章

    doi:10.1186/1472-6831-14-113

    authors: Kemaloğlu H,Tezel H,Ergücü Z

    更新日期:2014-09-06 00:00:00

  • Dental expenditure, progressivity and horizontal inequality in Chinese adults: based on the 4th National Oral Health Epidemiology Survey.

    abstract:BACKGROUND:The financial burden of oral diseases is a growing concern as the medical expenses rise worldwide. The aim of this study was to investigate the dental expenditure, analyze its progressivity and horizontal inequality under the general health finance and insurance system, and identify the key social determinan...

    journal_title:BMC oral health

    pub_type: 杂志文章

    doi:10.1186/s12903-020-01128-0

    authors: Cheng ML,Wang CX,Wang X,Feng XP,Tai BJ,De Hu Y,Lin HC,Wang B,Zheng SG,Liu XN,Rong WS,Wang WJ,Si Y,Xu T

    更新日期:2020-05-11 00:00:00

  • Candida prevalence and oral hygiene due to orthodontic therapy with conventional brackets.

    abstract:BACKGROUND:Conventional brackets are often used during orthodontic therapy of patients with malocclusion. The complex construction of such brackets greatly inhibits oral hygiene, which predisposes to increased carriage of microbiota. Orthodontic brackets could act as reservoir of yeast and predispose to oral candidosis...

    journal_title:BMC oral health

    pub_type: 杂志文章

    doi:10.1186/s12903-020-01267-4

    authors: Grzegocka K,Krzyściak P,Hille-Padalis A,Loster JE,Talaga-Ćwiertnia K,Loster BW

    更新日期:2020-10-10 00:00:00

  • Comparing the effect of 0.06% -, 0.12% and 0.2% Chlorhexidine on plaque, bleeding and side effects in an experimental gingivitis model: a parallel group, double masked randomized clinical trial.

    abstract:BACKGROUND:Chlorhexidine is the gold standard of dental plaque prevention. The aim of the present study was to compare the plaque and gingivitis inhibiting effect of commercial products containing 0.2%, 0.12% and 0.06% chlorhexidine in a modified experimental gingivitis model. METHODS:In three groups of healthy volunt...

    journal_title:BMC oral health

    pub_type: 杂志文章,随机对照试验

    doi:10.1186/s12903-017-0400-7

    authors: Haydari M,Bardakci AG,Koldsland OC,Aass AM,Sandvik L,Preus HR

    更新日期:2017-08-18 00:00:00

  • Malignant transformation in 5071 southern Taiwanese patients with potentially malignant oral mucosal disorders.

    abstract:BACKGROUND:Oral cancers can be preceded by clinically evident oral potentially malignant disorders (OPMDs). The current study evaluated the rate and the time of malignant transformation in the various OPMDs in a cohort of patients from southern Taiwan. Parameters possibly indicative for malignant transformation of OPMD...

    journal_title:BMC oral health

    pub_type: 杂志文章

    doi:10.1186/1472-6831-14-99

    authors: Wang YY,Tail YH,Wang WC,Chen CY,Kao YH,Chen YK,Chen CH

    更新日期:2014-08-05 00:00:00

  • Resistance to fracture of intraradicular posts made of biological materials.

    abstract:BACKGROUND:The aim was to analyze the fracture resistance of human teeth treated endodontically and restored with posts made of bovine dentin, human dentin, or glass fiber, and to evaluate the fracture pattern. METHODS:Cylindrical posts of 1.5 mm in diameter cemented to the roots of human maxillary canines presented a...

    journal_title:BMC oral health

    pub_type: 杂志文章

    doi:10.1186/s12903-020-01295-0

    authors: Tavano KTA,Botelho AM,Douglas-de-Oliveira DW,Avila AF,Huebner R

    更新日期:2020-11-03 00:00:00

  • Detection of vertical root fractures in endodontically treated teeth in the absence and in the presence of metal post by cone-beam computed tomography.

    abstract:BACKGROUND:Aim of this study was to investigate the influence of gutta-percha and metallic posts on the efficiency of Cone Beam Computed Tomography (CBCT) in diagnosing Vertical Root Fracture (VRF). METHODS:Forty-eight teeth were divided into 3 experimental and 3 control groups. The teeth of the first experimental gro...

    journal_title:BMC oral health

    pub_type: 杂志文章

    doi:10.1186/s12903-016-0207-y

    authors: Menezes RF,Araújo NC,Santa Rosa JM,Carneiro VS,Santos Neto AP,Costa V,Moreno LM,Miranda JM,de Albuquerque DS,Albuquerque M,Dos Santos RA,Gerbi ME

    更新日期:2016-04-14 00:00:00

  • Consequences of early extraction of compromised first permanent molar: a systematic review.

    abstract:BACKGROUND:The aim of this study was to systematically review the literature to determine the sequelae of early extraction of compromised first permanent molars (FPMs) with regard to the skeletal and dental development of 5- to 15-year-old children. Meta-analysis was conducted when applicable. METHODS:Our research pro...

    journal_title:BMC oral health

    pub_type: 杂志文章

    doi:10.1186/s12903-018-0516-4

    authors: Saber AM,Altoukhi DH,Horaib MF,El-Housseiny AA,Alamoudi NM,Sabbagh HJ

    更新日期:2018-04-05 00:00:00

  • Evaluation of the risk factors of dental caries in children with very low birth weight and normal birth weight.

    abstract:BACKGROUND:Health problems of premature infants can affect both general and oral health. The enamel defects, poor dietary and oral hygiene habits may predispose these children to dental caries. This study was conducted to assess the impact of very low birth weight and prematurity on caries risk in early childhood. MET...

    journal_title:BMC oral health

    pub_type: 杂志文章

    doi:10.1186/s12903-020-01372-4

    authors: Koberova R,Radochova V,Zemankova J,Ryskova L,Broukal Z,Merglova V

    更新日期:2021-01-07 00:00:00

  • An economic evaluation of maxillary implant overdentures based on six vs. four implants.

    abstract:BACKGROUND:The purpose of the present study was to assess the value for money achieved by bar-retained implant overdentures based on six implants compared with four implants as treatment alternatives for the edentulous maxilla. METHODS:A Markov decision tree model was constructed and populated with parameter estimates...

    journal_title:BMC oral health

    pub_type: 杂志文章

    doi:10.1186/1472-6831-14-105

    authors: Listl S,Fischer L,Giannakopoulos NN

    更新日期:2014-08-18 00:00:00

  • The effect of methamphetamine abuse on dental caries and periodontal diseases in an Eastern China city.

    abstract:BACKGROUND:Dental diseases are among the most frequently reported health problems in drug abusers. However, few studies have been conducted on oral health of methamphetamine (meth) abusers in China. The aim of the present study was to investigate the caries and periodontal health profile of former meth abusers in Easte...

    journal_title:BMC oral health

    pub_type: 杂志文章

    doi:10.1186/s12903-017-0463-5

    authors: Ye T,Sun D,Dong G,Xu G,Wang L,Du J,Ren P,Yu S

    更新日期:2018-01-10 00:00:00

  • Surgical suture course for dental students with the Peyton-4-step approach versus the PDCA cycle using video assisted self-monitoring.

    abstract:BACKGROUND:In this prospective study the Peyton 4-step approach of demonstration-deconstruction-comprehension (verbalization by the learner), and performance by the learner was compared to the PDCA cycle/Deming-Circle (Plan-Do-Check (video assisted self-monitoring)-Act) as a teaching method for surgical suturing and no...

    journal_title:BMC oral health

    pub_type: 杂志文章

    doi:10.1186/s12903-020-01309-x

    authors: Leitmann A,Reinert S,Weise H

    更新日期:2020-12-30 00:00:00