Abstract:
BACKGROUND:Chlorhexidine is the gold standard of dental plaque prevention. The aim of the present study was to compare the plaque and gingivitis inhibiting effect of commercial products containing 0.2%, 0.12% and 0.06% chlorhexidine in a modified experimental gingivitis model. METHODS:In three groups of healthy volunteers, experimental gingivitis was induced and monitored over 21 days and simultaneously treated with the commercial solutions containing 0.2%, 0.12% and 0.06% chlorhexidine. The maxillary right quadrant of each individual received mouthwash only, whereas the maxillary left quadrant was subject to both rinsing and mechanical oral hygiene. Compliance and side effects were monitored at days 7, 14, and 21. Plaque and gingivitis scores were obtained at baseline and day 21. RESULTS:The commercial mouthwash containing 0.2% chlorhexidine resulted in statistically significantly lower plaque scores than the 0.12 and 0.06% mouthwashes after 21 days use, whereas no statistically significant difference was found between the effects of the two latter. CONCLUSION:A commercially available mouthwash containing 0.2% chlorhexidine had statistically significant better effect in preventing dental plaque than the 0.12% and 0.06% solutions. TRIAL REGISTRATION:ClinicalTrials.gov NCT02911766 . Registration date: September 9th 2016.
journal_name
BMC Oral Healthjournal_title
BMC oral healthauthors
Haydari M,Bardakci AG,Koldsland OC,Aass AM,Sandvik L,Preus HRdoi
10.1186/s12903-017-0400-7subject
Has Abstractpub_date
2017-08-18 00:00:00pages
118issue
1issn
1472-6831pii
10.1186/s12903-017-0400-7journal_volume
17pub_type
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