Frailty predicts worse outcomes after intracranial meningioma surgery irrespective of existing prognostic factors.

Abstract:

OBJECTIVE:Frailty has been recognized as a predictor of adverse surgical outcomes across multiple surgical disciplines, but until now the relationship between frailty and intracranial meningioma surgery has not been studied. The goal of the present study was to determine the relationship between increasing frailty (determined using the modified Frailty Index [mFI]) and intracranial meningioma resection outcomes (including hospital length of stay [LOS], discharge location, and reoperation and readmission rates). METHODS:This is a single-center retrospective cohort study of patients who underwent intracranial meningioma resection between August 2012 and May 2018. Seventy-six patients met the inclusion criteria. RESULTS:Frailty was associated with increased hospital LOS (p = 0.0218), increased reoperation rate (p = 0.029), and discharge to a higher level of care: an inpatient rehabilitation facility or a skilled nursing facility (p = 0.0002). After multivariable analysis, frailty was determined to be an independent risk factor for increased LOS, worse discharge disposition, and subsequent readmission. CONCLUSIONS:Frailty is an independent risk factor for worse outcomes following intracranial meningioma resection, including increased LOS, reoperations, and worse discharge disposition. Frailty may help stratify preoperative surgical risk, and thus may provide important clinical information to help neurosurgeons and elderly patients weigh the risks and benefits of resection.

journal_name

Neurosurg Focus

journal_title

Neurosurgical focus

authors

Theriault BC,Pazniokas J,Adkoli AS,Cho EK,Rao N,Schmidt M,Cole C,Gandhi C,Couldwell WT,Al-Mufti F,Bowers CA

doi

10.3171/2020.7.FOCUS20324

subject

Has Abstract

pub_date

2020-10-01 00:00:00

pages

E16

issue

4

issn

1092-0684

pii

2020.7.FOCUS20324

journal_volume

49

pub_type

杂志文章
  • Nerve root anomalies: implications for transforaminal lumbar interbody fusion surgery and a review of the Neidre and Macnab classification system.

    abstract::Lumbar nerve root anomalies are uncommon phenomena that must be recognized to avoid neural injury during surgery. The authors describe 2 cases of nerve root anomalies encountered during mini-open transforaminal lumbar interbody fusion (TLIF) surgery. One anomaly was a confluent variant not previously classified; the a...

    journal_title:Neurosurgical focus

    pub_type: 杂志文章

    doi:10.3171/2013.2.FOCUS1349

    authors: Burke SM,Safain MG,Kryzanski J,Riesenburger RI

    更新日期:2013-08-01 00:00:00

  • Medical management of cerebral edema.

    abstract::Cerebral edema is frequently encountered in clinical practice in critically ill patients with acute brain injury from diverse origins and is a major cause of increased morbidity and death in this subset of patients. The consequences of cerebral edema can be lethal and include cerebral ischemia from compromised regiona...

    journal_title:Neurosurgical focus

    pub_type: 杂志文章,评审

    doi:10.3171/foc.2007.22.5.13

    authors: Raslan A,Bhardwaj A

    更新日期:2007-05-15 00:00:00

  • Partial labyrinthectomy presigmoid transpetrosal resection of petroclival meningioma.

    abstract::A petroclival meningioma represents a challenging tumor to resect in the cerebellopontine angle and ventral to the brain stem. Multiple cranial nerves and blood vessels may be intimately involved with the tumor. A partial labyrinthectomy presigmoid transpetrosal approach can facilitate resection while preserving heari...

    journal_title:Neurosurgical focus

    pub_type: 杂志文章

    doi:10.3171/2014.V1.FOCUS13425

    authors: Rodgers SD,McMenomey SO,Sen C

    更新日期:2014-01-01 00:00:00

  • Spontaneous thrombosis of neonatal vein of Galen malformation.

    abstract::Vein of Galen malformations are rare congenital intracranial vascular malformations. Based on reports in the literature, spontaneous thrombosis or regression of these lesions is rare. Patients have variable outcomes from an asymptomatic course to death. The reasons behind spontaneous thrombosis are not entirely unders...

    journal_title:Neurosurgical focus

    pub_type: 杂志文章

    doi:10.3171/2009.8.FOCUS09162

    authors: Moftakhar P,Danielpour M,Maya M,Alexander MJ

    更新日期:2009-11-01 00:00:00

  • A rare, delayed complication of a ventriculogallbladder shunt. Case report and review of the literature.

    abstract::The use of the gallbladder as an alternative cerebrospinal fluid diversion site has been previously described in cases in which all other body cavities, such as the peritoneal cavity, right atrium, or pleural cavity, have been exhausted. Various ventriculogallbladder (VG) shunt complications have been described as wel...

    journal_title:Neurosurgical focus

    pub_type: 杂志文章,评审

    doi:10.3171/foc.2007.22.4.14

    authors: Fountas KN,Kassam MA,Grigorian AA

    更新日期:2007-04-15 00:00:00

  • Need for standard outcome reporting systems in craniosynostosis.

    abstract::Craniosynostosis is the premature fusion of one or more cranial sutures. When a cranial suture fuses prematurely, skull growth is altered and the head takes on a characteristic pathological shape determined by the suture(s) that fuses. Numerous treatment options have been proposed, but until recently there were no par...

    journal_title:Neurosurgical focus

    pub_type: 杂志文章,评审

    doi:10.3171/2011.6.FOCUS1192

    authors: Szpalski C,Weichman K,Sagebin F,Warren SM

    更新日期:2011-08-01 00:00:00

  • Ossification of the posterior longitudinal ligament in non-Asians: demographic, clinical, and radiographic findings in 43 patients.

    abstract:OBJECT:Ossification of the posterior longitudinal ligament (OPLL) is a disorder afflicting as many as 2% of East Asians. However, reports of OPLL in non-Asians have been sporadic in the medical literature. This study describes clinical and radiographic findings with OPLL in non-Asians at a tertiary care center treating...

    journal_title:Neurosurgical focus

    pub_type: 杂志文章

    doi:10.3171/2010.12.FOCUS10277

    authors: Wang MY,Thambuswamy M

    更新日期:2011-03-01 00:00:00

  • Intraoperative optical intrinsic signal imaging: a clinical tool for functional brain mapping.

    abstract::Optical imaging of intrinsic signals (OIS) is a well-established neuroimaging modality by which functional cortical activity is mapped by detecting activity-related changes in cortical light reflectance. Light reflectance changes are detected by a charged-coupled device camera that captures images of the exposed corte...

    journal_title:Neurosurgical focus

    pub_type: 杂志文章,评审

    doi:10.3171/foc.2002.13.4.2

    authors: Pouratian N,Cannestra AF,Martin NA,Toga AW

    更新日期:2002-10-15 00:00:00

  • Comparison between anterior and posterior decompression with instrumentation for cervical spondylotic myelopathy: sagittal alignment and clinical outcome.

    abstract:OBJECT:A variety of anterior, posterior, and combined approaches exist to decompress the spinal cord, restore sagittal alignment, and avoid kyphosis, but the optimal surgical strategy remains controversial. The authors compared the anterior and posterior approach used to treat multilevel cervical spondylotic myelopathy...

    journal_title:Neurosurgical focus

    pub_type: 杂志文章

    doi:10.3171/2010.1.FOCUS09253

    authors: Cabraja M,Abbushi A,Koeppen D,Kroppenstedt S,Woiciechowsky C

    更新日期:2010-03-01 00:00:00

  • Upward transtentorial herniation following frontoorbital advancement for syndromic craniosynostosis: case report.

    abstract::The authors describe the case of a boy with Muenke syndrome, an autosomal dominant disorder associated with craniosynostosis. The family history was significant for syndromic craniosynostosis in the patient's maternal grandmother, who died in adulthood after a craniofacial reconstruction. The patient, her grandson, un...

    journal_title:Neurosurgical focus

    pub_type: 杂志文章

    doi:10.3171/2015.2.FOCUS151

    authors: Mehta V,Bakhsheshian J,Dorafshar AH,Ahn ES

    更新日期:2015-05-01 00:00:00

  • The axial transsacral approach to interbody fusion at L5-S1.

    abstract::Lumbosacral interbody fusion may be indicated to treat degenerative disc disease at L5-S1, instability or spondylolisthesis at that level, and severe neural foraminal stenosis resulting from loss of disc space height. In addition, L5-S1 interbody fusion may provide anterior support to a long posterior fusion construct...

    journal_title:Neurosurgical focus

    pub_type: 杂志文章,评审

    doi:10.3171/2014.2.FOCUS13467

    authors: Issack PS,Kotwal SY,Boachie-Adjei O

    更新日期:2014-05-01 00:00:00

  • A comparison of minimally invasive posterior cervical decompression and open anterior cervical decompression and instrumented fusion in the surgical management of degenerative cervical myelopathy.

    abstract::OBJECTIVE Minimally invasive posterior cervical decompression (miPCD) has been described in several case series with promising preliminary results. The object of the current study was to compare the clinical outcomes between patients undergoing miPCD with anterior cervical discectomy and instrumented fusion (ACDFi). M...

    journal_title:Neurosurgical focus

    pub_type: 杂志文章

    doi:10.3171/2016.3.FOCUS1650

    authors: Abbas SF,Spurgas MP,Szewczyk BS,Yim B,Ata A,German JW

    更新日期:2016-06-01 00:00:00

  • Decision making for patients with multiple brain metastases: radiosurgery, radiotherapy, or resection?

    abstract:OBJECT:Multiple brain metastases are a common health problem, frequently found in patients with cancer. The prognosis, even after treatment with whole-brain radiation therapy (WBRT), is poor, with an average expected survival time of less than 6 months. Investigators at numerous centers have evaluated the role of stere...

    journal_title:Neurosurgical focus

    pub_type: 杂志文章,随机对照试验

    doi:10.3171/foc.2000.9.2.5

    authors: Kondziolka D,Patel A,Lunsford LD,Flickinger JC

    更新日期:2000-08-15 00:00:00

  • On the design of robotic hands for brain-machine interface.

    abstract::Brain-machine interface (BMI) is the latest solution to a lack of control for paralyzed or prosthetic limbs. In this paper the authors focus on the design of anatomical robotic hands that use BMI as a critical intervention in restorative neurosurgery and they justify the requirement for lower-level neuromusculoskeleta...

    journal_title:Neurosurgical focus

    pub_type: 杂志文章,评审

    doi:10.3171/foc.2006.20.5.4

    authors: Matsuoka Y,Afshar P,Oh M

    更新日期:2006-05-15 00:00:00

  • Cost-effectiveness of adult spinal deformity surgery in a military healthcare system.

    abstract::OBJECTIVEAdult spinal deformity surgery is an effective way of treating pain and disability, but little research has been done to evaluate the costs associated with changes in health outcome measures. This study determined the change in quality-adjusted life years (QALYs) and the cost per QALY in patients undergoing s...

    journal_title:Neurosurgical focus

    pub_type: 杂志文章

    doi:10.3171/2018.9.FOCUS18381

    authors: Neal CJ,Mandell K,Tasikas E,Delaney JJ,Miller CA,Schlaff CD,Rosner MK

    更新日期:2018-12-01 00:00:00

  • Stereotactic radiosurgery for functional disorders.

    abstract::Stereotactic radiosurgery (SRS) with the Gamma Knife and linear accelerator has revolutionized neurosurgery over the past 20 years. The most common indications for radiosurgery today are tumors and arteriovenous malformations of the brain. Functional indications such as treatment of movement disorders or intractable p...

    journal_title:Neurosurgical focus

    pub_type: 杂志文章,评审

    doi:10.3171/FOC-07/12/E3

    authors: Friehs GM,Park MC,Goldman MA,Zerris VA,Norén G,Sampath P

    更新日期:2007-01-01 00:00:00

  • Lumbosacral ependymomas: a review of the management of intradural and extradural tumors.

    abstract:OBJECT:The goal of this study was to review the management of intra- and extradural ependymomas. Spinal ependymomas most commonly occur as intramedullary tumors throughout the spinal axis. In the lumbosacral region, ependymomas are most commonly associated with the conus medullaris and cauda equina, but can also occur ...

    journal_title:Neurosurgical focus

    pub_type: 杂志文章,评审

    doi:10.3171/foc.2003.15.5.13

    authors: Fassett DR,Schmidt MH

    更新日期:2003-11-15 00:00:00

  • Contemporary health care economics: an overview.

    abstract::Economic evaluations provide a decision-making framework in which outcomes (benefits) and costs are assessed for various alternative options. Although the interest in complete and partial economic evaluations has increased over the past 2 decades, the quality of studies has been marginal due to methodological challeng...

    journal_title:Neurosurgical focus

    pub_type: 杂志文章,评审

    doi:10.3171/2014.8.FOCUS14455

    authors: McLaughlin N,Ong MK,Tabbush V,Hagigi F,Martin NA

    更新日期:2014-11-01 00:00:00

  • Transarterial embolization of an internal maxillary artery arteriovenous fistula presenting with pulsatile tinnitus.

    abstract::Arteriovenous fistulae of the internal maxillary artery are exceedingly rare, with less than 30 cases reported in the literature. Most of these lesions are congenital, iatrogenic, or posttraumatic. The most common presentation of internal maxillary artery fistulae is pulsatile tinnitus and headache. Because these lesi...

    journal_title:Neurosurgical focus

    pub_type: 杂志文章

    doi:10.3171/2019.1.FocusVid.18479

    authors: Brinjikji W,Cloft HJ,Lanzino G,Rangel-Castilla L,Morris PP

    更新日期:2019-01-01 00:00:00

  • Vascular architecture mapping for early detection of glioblastoma recurrence.

    abstract:OBJECTIVE:Treatment failure and inevitable tumor recurrence are the main reasons for the poor prognosis of glioblastoma (GB). Gross-total resection at repeat craniotomy for GB recurrence improves patient overall survival but requires early and reliable detection. It is known, however, that even advanced MRI approaches ...

    journal_title:Neurosurgical focus

    pub_type: 杂志文章

    doi:10.3171/2019.9.FOCUS19613

    authors: Stadlbauer A,Eyüpoglu I,Buchfelder M,Dörfler A,Zimmermann M,Heinz G,Oberndorfer S

    更新日期:2019-12-01 00:00:00

  • Percival Bailey and the classification of brain tumors.

    abstract::Throughout his illustrious career, Percival Bailey made numerous contributions to the fields of neurology, neuroanatomy, psychiatry, neuropathology, and, of course, neurosurgery. His expertise, his curiosity about the nervous system, and his desire to examine it from all angles were unique. With the exception of Harve...

    journal_title:Neurosurgical focus

    pub_type: 传,历史文章,杂志文章,评审

    doi:10.3171/foc.2005.18.4.8

    authors: Ferguson S,Lesniak MS

    更新日期:2005-04-15 00:00:00

  • 5-ALA-induced fluorescence as a marker for diagnostic tissue in stereotactic biopsies of intracranial lymphomas: experience in 41 patients.

    abstract::OBJECTIVE Stereotactic needle biopsies are usually performed for histopathological confirmation of intracranial lymphomas to guide adequate treatment. During biopsy, intraoperative histopathology is an effective tool to avoid acquisition of nondiagnostic samples. In the last years, 5-aminolevulinic acid (5-ALA)-induce...

    journal_title:Neurosurgical focus

    pub_type: 杂志文章

    doi:10.3171/2018.3.FOCUS1859

    authors: Kiesel B,Millesi M,Woehrer A,Furtner J,Bavand A,Roetzer T,Mischkulnig M,Wolfsberger S,Preusser M,Knosp E,Widhalm G

    更新日期:2018-06-01 00:00:00

  • Surgical approaches for resection of vestibular schwannomas: translabyrinthine, retrosigmoid, and middle fossa approaches.

    abstract::Surgical removal remains one of the key treatment modalities for vestibular schwannomas. A team approach between a neurotologist and a neurosurgeon offers the patient the expertise of both specialties and maximizes the chances for an optimal outcome. Vestibular schwannomas can typically be resected through 1 of 3 main...

    journal_title:Neurosurgical focus

    pub_type: 杂志文章,评审

    doi:10.3171/2012.6.FOCUS12190

    authors: Chamoun R,MacDonald J,Shelton C,Couldwell WT

    更新日期:2012-09-01 00:00:00

  • Enhanced recovery after spine surgery: a systematic review.

    abstract::OBJECTIVEEnhanced recovery after surgery (ERAS) is a multidimensional approach to improving the care of surgical patients using subspecialty- and procedure-specific evidence-based protocols. The literature provides evidence of the benefits of ERAS implementation, which include expedited functional recovery, decreased ...

    journal_title:Neurosurgical focus

    pub_type: 杂志文章

    doi:10.3171/2019.1.FOCUS18700

    authors: Elsarrag M,Soldozy S,Patel P,Norat P,Sokolowski JD,Park MS,Tvrdik P,Kalani MYS

    更新日期:2019-04-01 00:00:00

  • What neurosurgeons should do to succeed in tomorrow's scientific and socioeconomic environment.

    abstract::There will be major scientific advances and socioeconomic changes in the 21st century that will influence the development of medicine and neurosurgery. These changes will affect those in academic medical centers and the private practitioners of medicine and neurosurgery. Neurosurgeons' philosophy and practice methods ...

    journal_title:Neurosurgical focus

    pub_type: 杂志文章

    doi:10.3171/foc.2002.12.4.10

    authors: Ausman JI,Pawl RP

    更新日期:2002-04-15 00:00:00

  • Phototherapy in peripheral nerve regeneration: From basic science to clinical study.

    abstract:OBJECT:This review summarizes the continuous study of low-power laser radiation treatment of a severely injured peripheral nerve. Laser phototherapy was applied as a supportive factor for accelerating and enhancing axonal growth and regeneration after injury or a reconstructive peripheral nerve procedure. In nerve cell...

    journal_title:Neurosurgical focus

    pub_type: 杂志文章

    doi:10.3171/FOC.2009.26.2.E8

    authors: Rochkind S

    更新日期:2009-02-01 00:00:00

  • Comparison of manually shaped and computer-shaped titanium mesh for repairing large frontotemporoparietal skull defects after traumatic brain injury.

    abstract:OBJECT:The object of this study was to compare the effects and complications of manual and computer-aided shaping of titanium meshes for repairing large frontotemporoparietal skull defects following traumatic brain injury. METHODS:From March 2005 to June 2011, 161 patients with frontotemporoparietal skull defects were...

    journal_title:Neurosurgical focus

    pub_type: 杂志文章

    doi:10.3171/2012.2.FOCUS129

    authors: Luo J,Liu B,Xie Z,Ding S,Zhuang Z,Lin L,Guo Y,Chen H,Yu X

    更新日期:2012-07-01 00:00:00

  • Neurosurgical applications of viscoelastic hemostatic assays.

    abstract::Patients taking antithrombotic agents are very common in neurosurgical practice. The perioperative management of these patients can be extremely challenging especially as newer agents, with poorly defined laboratory monitoring and reversal strategies, become more prevalent. This is especially true with emergent cases ...

    journal_title:Neurosurgical focus

    pub_type: 杂志文章,评审

    doi:10.3171/2017.8.FOCUS17447

    authors: Kvint S,Schuster J,Kumar MA

    更新日期:2017-11-01 00:00:00

  • Thoracoscopic surgery: historical perspectives.

    abstract::Recent technical advances have revolutionized the fields of surgical endoscopy, laparoscopy, thoracoscopy, and microsurgical spinal endoscopy. The authors discuss the rich history and recent evolution of these techniques. Thoracoscopy had been widely used for the treatment of pleural conditions associated with tubercu...

    journal_title:Neurosurgical focus

    pub_type: 历史文章,杂志文章

    doi:10.3171/foc.2000.9.4.10

    authors: Das K,Rothberg M

    更新日期:2000-10-15 00:00:00

  • The genetic basis of intradural spinal tumors and its impact on clinical treatment.

    abstract::Genetic alterations in the cells of intradural spinal tumors can have a significant impact on the treatment options, counseling, and prognosis for patients. Although surgery is the primary therapy for most intradural tumors, radiochemothera-peutic modalities and targeted interventions play an ever-evolving role in tre...

    journal_title:Neurosurgical focus

    pub_type: 杂志文章,评审

    doi:10.3171/2015.5.FOCUS15143

    authors: Karsy M,Guan J,Sivakumar W,Neil JA,Schmidt MH,Mahan MA

    更新日期:2015-08-01 00:00:00