In vitro assembly of nuclear envelope in tobacco cultured cells.

abstract：OBJECTIVE:Recombinant factor VIIa can decrease postoperative bleeding after cardiac surgery. However, the potential for recombinant factor VIIa to cause early vascular graft occlusion at the site of new vascular anastomoses has not been fully explored. We hypothesized that recombinant factor VIIa would cause a dose-dep...

journal_title：Nucleus (Austin, Tex.)

authors： Coffinier C,Fong LG,Young SG

更新日期：2010-09-01 00:00:00

abstract：:Attempts to promote normal processing and function of F508del-CFTR, the most common mutant in cystic fibrosis (CF), have been described as potential therapeutic strategies in the management of this disease. Here we described the proteomic approaches, namely two-dimensional electrophoresis (2DE), mass spectrometry (MS)...

journal_title：Nucleus (Austin, Tex.)

authors： Ahmed S,Brickner JH

更新日期：2010-09-01 00:00:00

abstract：:Attempts to promote normal processing and function of F508del-CFTR, the most common mutant in cystic fibrosis (CF), have been described as potential therapeutic strategies in the management of this disease. Here we described the proteomic approaches, namely two-dimensional electrophoresis (2DE), mass spectrometry (MS)...

journal_title：Nucleus (Austin, Tex.)

authors： Gonzalez-Suarez I,Gonzalo S

更新日期：2010-03-01 00:00:00

abstract：:Attempts to promote normal processing and function of F508del-CFTR, the most common mutant in cystic fibrosis (CF), have been described as potential therapeutic strategies in the management of this disease. Here we described the proteomic approaches, namely two-dimensional electrophoresis (2DE), mass spectrometry (MS)...

journal_title：Nucleus (Austin, Tex.)

authors： Li B

更新日期：2010-05-01 00:00:00

abstract：:Attempts to promote normal processing and function of F508del-CFTR, the most common mutant in cystic fibrosis (CF), have been described as potential therapeutic strategies in the management of this disease. Here we described the proteomic approaches, namely two-dimensional electrophoresis (2DE), mass spectrometry (MS)...

journal_title：Nucleus (Austin, Tex.)

authors： Linde N,Stick R

更新日期：2010-07-01 00:00:00

abstract：:Attempts to promote normal processing and function of F508del-CFTR, the most common mutant in cystic fibrosis (CF), have been described as potential therapeutic strategies in the management of this disease. Here we described the proteomic approaches, namely two-dimensional electrophoresis (2DE), mass spectrometry (MS)...

journal_title：Nucleus (Austin, Tex.)

authors： Bar DZ,Gruenbaum Y

更新日期：2010-11-01 00:00:00

abstract：:Attempts to promote normal processing and function of F508del-CFTR, the most common mutant in cystic fibrosis (CF), have been described as potential therapeutic strategies in the management of this disease. Here we described the proteomic approaches, namely two-dimensional electrophoresis (2DE), mass spectrometry (MS)...

journal_title：Nucleus (Austin, Tex.)

authors： Langowski J

更新日期：2010-01-01 00:00:00

abstract：:Plant aerial parts are differentiated from stem cells that are located in the shoot apical meristem (SAM). CLAVATA3 (CLV3)-CLV1 is a well-known ligand-receptor pair, which functions in SAM maintenance. In Lotus japonicus, HYPERNODULATION ABERRANT ROOT FORMATION1 (HAR1) shows the highest similarity with CLV1 of all Ara...

journal_title：Nucleus (Austin, Tex.)

authors： Davies BS,Coffinier C,Yang SH,Barnes RH 2nd,Jung HJ,Young SG,Fong LG

更新日期：2011-01-01 00:00:00

abstract：:The new fluorescent Na+ indicator sodium-binding benzofuran isophthalate (SBFI) was used for determination of the cytosolic free Na+ concentration, [Na+]i, in human platelets. The dye could be loaded into platelets in the form of its acetoxymethyl ester (SBFI-AM). Calibration of the fluorescence in terms of [Na+]i was...

journal_title：Nucleus (Austin, Tex.)

authors： Erdel F,Rippe K

更新日期：2011-03-01 00:00:00

abstract：BACKGROUND/AIM:Implantation failure after embryo transfer is one of the main problems of in vitro fertilization (IVF) and intrauterine pathologies can lead to unsuccessful outcome. The aim of this study was to determine if hysteroscopic examination of uterine cavity and consequent treatment of intrauterine lesions prio...

journal_title：Nucleus (Austin, Tex.)

authors： Kubben N,Voncken JW,Konings G,van Weeghel M,van den Hoogenhof MM,Gijbels M,van Erk A,Schoonderwoerd K,van den Bosch B,Dahlmans V,Calis C,Houten SM,Misteli T,Pinto YM

更新日期：2011-05-01 00:00:00

abstract：BACKGROUND:Previous studies have suggested that the use of mesh in groin hernia repair may be associated with an increased risk for male infertility as a result of inflammatory obliteration of structures in the spermatic cord. In a recent study, we could not find an increased incidence of involuntary childlessness. The...

journal_title：Nucleus (Austin, Tex.)

authors： Abou-Ellail M,Cooke R,Sáez-Vásquez J

更新日期：2011-07-01 00:00:00

abstract：BACKGROUND:Cancer patients frequently suffer from weight loss and systemic inflammation in the context of advanced disease, which is related to adverse outcome. Insulin-like growth factor (IGF)-I is an anabolic molecule implicated in the maintenance of muscle mass and cancer growth. We investigated potential correlatio...

journal_title：Nucleus (Austin, Tex.)

authors： Al-Haboubi T,Shumaker DK,Köser J,Wehnert M,Fahrenkrog B

更新日期：2011-09-01 00:00:00

abstract：:Airways are continually exposed to multiple inhaled oxidants and protect themselves with cellular and extracellular antioxidants throughout the epithelial lining fluid and tissues. Oxidative stress, resulting from the increased oxidative burden and decreased level of antioxidant proteins, is involved in cellular and t...

journal_title：Nucleus (Austin, Tex.)

authors： Tachiwana H,Kagawa W,Kurumizaka H

更新日期：2012-01-01 00:00:00

abstract：:Animal models have been extensively used in the study of cardiovascular disease (CVD) and have provided important insights into disease pathogenesis and drug development. However, the level of conservation of gene expression patterns of the orthologous genes between human and animal models was unclear. To address this...

journal_title：Nucleus (Austin, Tex.)

authors： Horigome C,Mizuta K

更新日期：2012-01-01 00:00:00

abstract：:Lactobacillus sakei is a meat-borne lactic acid bacterium species exhibiting a wide genomic diversity. We have investigated the diversity of response to various oxidative compounds, between L. sakei strains, among a collection representing the genomic diversity. We observed various responses to the different compounds...

journal_title：Nucleus (Austin, Tex.)

authors： Marko JF

更新日期：2012-03-01 00:00:00

abstract：:In female mouse embryos, somatic cells undergo a random form of X chromosome inactivation (XCI), whereas extraembryonic trophoblast cells in the placenta undergo imprinted XCI, silencing exclusively the paternal X chromosome. Initiation of imprinted XCI requires a functional maternal allele of the X-linked gene Rnf12,...

journal_title：Nucleus (Austin, Tex.)

authors： Izumi N,Yamashita A,Ohno S

更新日期：2012-01-01 00:00:00

abstract：PURPOSE:Undertaking observer studies to compare imaging technology using clinical radiological images is challenging due to patient variability. To achieve a significant result, a large number of patients would be required to compare cancer detection rates for different image detectors and systems. The aim of this work...

journal_title：Nucleus (Austin, Tex.)

authors： Clever M,Funakoshi T,Mimura Y,Takagi M,Imamoto N

更新日期：2012-03-01 00:00:00

abstract：:Portugal, in 2005, initiated to reconfigure its health centers, an action referred to as the reform of primary health care, with the objective to improve accessibility, efficiency, quality and the continuity of care, and increase the satisfaction of the population and the professionals. The health center groups were r...

journal_title：Nucleus (Austin, Tex.)

authors： Vargas JD,Hatch EM,Anderson DJ,Hetzer MW

更新日期：2012-01-01 00:00:00

abstract：OBJECTIVE:Primary progressive aphasia (PPA) has been proposed to comprise 3 discrete clinical subtypes: semantic, agrammatic/nonfluent, and logopenic. Recent consensus recommendations suggest a diagnostic framework based primarily on clinical and neuropsychological findings to classify these variants. Our objective was...

journal_title：Nucleus (Austin, Tex.)

authors： Söderberg E,Hessle V,von Euler A,Visa N

更新日期：2012-05-01 00:00:00

abstract：:A set of general principles can guide preclinical testing strategies for evaluating the tumorigenicity of regenerative medicine products. ...

journal_title：Nucleus (Austin, Tex.)

authors： Jahn D,Schramm S,Schnölzer M,Heilmann CJ,de Koster CG,Schütz W,Benavente R,Alsheimer M

更新日期：2012-09-01 00:00:00

abstract：:Studies on the relationship between obesity and bone have recently become widespread. The aim of this study was to investigate the effect of obesity on bone, utilizing a diet-induced obese mouse model, and to explore the role of free fatty acids (FFAs) in the osteogenesis/adipogenesis of mouse bone marrow-derived mese...

journal_title：Nucleus (Austin, Tex.)

authors： Field MC,Horn D,Alsford S,Koreny L,Rout MP

更新日期：2012-11-01 00:00:00

abstract：OBJECTIVES:The aim was to develop a long-term delivery system for Apo2 ligand/tumour necrosis factor-related apoptosis-inducing ligand (TRAIL) without chemical modification (such as pegylation). METHODS:A nanocomplex system between the positively charged TRAIL and the negatively charged chondroitin sulfate (CS) (CS/TR...

journal_title：Nucleus (Austin, Tex.)

authors： Volk T

更新日期：2013-01-01 00:00:00

abstract：BACKGROUND AND AIMS:To assess the harms of colonoscopy in a real world colorectal cancer screening programme with faecal occult blood test. METHODS:Retrospective cohort study of all colonoscopies performed in patients aged 50-74 for a positive guaiac-based faecal occult blood test between September 2003 and February 2...

journal_title：Nucleus (Austin, Tex.)

authors： Tu S,Pederson T,Weng Z

更新日期：2013-03-01 00:00:00

abstract：INTRODUCTION:The inefficacy of clinical skill education during the clerkship has been reported in several studies. The present study was conducted to evaluate the competency of medical students in performing several clinical skills through an Objective Structured Clinical Examination (OSCE), aiming to evaluate the qual...

journal_title：Nucleus (Austin, Tex.)

authors： Hou H,Kallgren SP,Jia S

更新日期：2013-05-01 00:00:00

abstract：:The experimenters explored how religious fundamentalism related with religious orientation, irrational thinking, and immature defense mechanisms. They also explored the possible moderational role of the Big 5 personality factors. The participants were predominantly Greek Orthodox College students from a Cypriot Univer...

journal_title：Nucleus (Austin, Tex.)

authors： Politz JC,Ragoczy T,Groudine M

更新日期：2013-05-01 00:00:00

abstract：BACKGROUND:Among the expected benefits of electronic health records (EHRs) is increased reporting of public health information, such as immunization status. State and local immunization registries aid control of vaccine-preventable diseases and help offset fragmentation in healthcare, but reporting is often slow and in...

journal_title：Nucleus (Austin, Tex.)

authors： Dreesen O,Ong PF,Chojnowski A,Colman A

更新日期：2013-07-01 00:00:00

abstract：BACKGROUND:An association between resting heart rate (RHR) and cardiovascular morbidity and mortality has been shown in patients with coronary artery disease (CAD). We aimed to evaluate the RHR and its relationship with clinical variables in outpatients with stable CAD at secondary and tertiary care centers in Turkey. ...

journal_title：Nucleus (Austin, Tex.)

authors： Lu P,Roberts CW

更新日期：2013-09-01 00:00:00

abstract：OBJECTIVE:This study was conducted to describe the frequency of diabetes in dental patients, and to compare three different screening methods: the random finger plasma glucose (RFPG) test, the Finnish diabetes risk score (FINDRISC) survey and a special clinical guideline developed for dental patients. METHODS:The stud...

journal_title：Nucleus (Austin, Tex.)

authors： Poleshko A,Katz RA

更新日期：2014-01-01 00:00:00

abstract：OBJECTIVE:This study was conducted to describe the frequency of diabetes in dental patients, and to compare three different screening methods: the random finger plasma glucose (RFPG) test, the Finnish diabetes risk score (FINDRISC) survey and a special clinical guideline developed for dental patients. METHODS:The stud...

journal_title：Nucleus (Austin, Tex.)

authors： Récamier V,Izeddin I,Bosanac L,Dahan M,Proux F,Darzacq X

更新日期：2014-01-01 00:00:00

abstract：BACKGROUND:The single-dose benzimidazoles used against Trichuris trichiura infections in humans are not satisfactory. Likewise, the benzimidazole, fenbendazole, has varied efficacy against Trichuris suis whereas Oesophagostomum dentatum is highly sensitive to the drug. The reasons for low treatment efficacy of Trichuri...

journal_title：Nucleus (Austin, Tex.)

authors： Beck M,Glavy JS

更新日期：2014-03-01 00:00:00