Abstract:
BACKGROUND:There is limited information about the clinical characteristics, treatment and outcome of maintenance hemodialysis patients with COVID-19. Moreover, regional differences are also conceivable since the extend and severity of outbreaks varied among countries. METHODS:In this retrospective, observational, single-center study, we analyzed the clinical course and outcomes of 37 maintenance hemodialysis patients (median age 64 years, 51% men) hospitalized with COVID-19 from 24 March to 22 May 2020 as confirmed by real-time PCR. RESULTS:The most common symptoms at admission were fatigue (51%), fever (43%), dyspnea (38%) and cough (35%). There were 59% mild/moderate patients and 41% severe/critical patients. Patients in the severe/critical group had a significantly higher atherosclerotic burden since diabetic kidney disease and vascular nephropathies were the most common primary kidney diseases and eighty percent of them had coronary heart disease. Also, Charlson comorbidity score was higher in this group. At admission chest X-ray, 46% had ground-glass abnormalities. Overall, 60% patients received hydroxychloroquine, 22% lopinavir-ritonavir, 11% tocilizumab, 24% systemic glucocorticoids, and 54% received prophylactic anticoagulation. Seven (19%) patients died during hospitalization and 30 were discharged. The main causes of death were cardiovascular (5 patients) and respiratory distress syndrome (2 patients). In Cox regression analysis, lower oxygen saturation, anemia and hypoalbuminemia at admission were associated with increased mortality. CONCLUSIONS:In conclusion, we observed a high mortality rate among maintenance hemodialysis patients hospitalized for COVID-19. Anemia, lower serum albumin and lower basal oxygen saturation at admission were factors associated with poor prognosis.
journal_name
Ren Failjournal_title
Renal failureauthors
Stefan G,Mehedinti AM,Andreiana I,Zugravu AD,Cinca S,Busuioc R,Miler I,Stancu S,Petrescu L,Dimitriu I,Moldovanu E,Crasnaru DE,Gugonea G,Georgescu V,Strambu VD,Capusa Cdoi
10.1080/0886022X.2020.1853571keywords:
["COVID-19","chronic hemodialysis","clinical features","mortality"]subject
Has Abstractpub_date
2021-12-01 00:00:00pages
49-57issue
1eissn
0886-022Xissn
1525-6049journal_volume
43pub_type
杂志文章相关文献
文献大全abstract::1. In the present study, two new peptides, phrixotoxins PaTx1 and PaTx2 (29-31 amino acids), which potently block A-type potassium currents, have been purified from the venom of the tarantula Phrixotrichus auratus. 2. Phrixotoxins specifically block Kv4.3 and Kv4.2 currents that underlie I(to1), with an 5 < IC50 < 70 ...
journal_title:Renal failure
pub_type: 杂志文章
doi:10.3109/08860229909066965
更新日期:1999-01-01 00:00:00
abstract::1. In the present study, two new peptides, phrixotoxins PaTx1 and PaTx2 (29-31 amino acids), which potently block A-type potassium currents, have been purified from the venom of the tarantula Phrixotrichus auratus. 2. Phrixotoxins specifically block Kv4.3 and Kv4.2 currents that underlie I(to1), with an 5 < IC50 < 70 ...
journal_title:Renal failure
pub_type: 杂志文章
doi:10.3109/08860229909066975
更新日期:1999-01-01 00:00:00
abstract:OBJECTIVE:To investigate the eradication rate of Helicobacter pylori with omeprazole, amoxicillin and clarithromycin during 6 days in patients with duodenal ulcer. To compare the reliability of the analysis of the eradication with urea-13C breath test performed one month and 3 months after therapy. To evaluate the one-...
journal_title:Renal failure
pub_type: 杂志文章,评审
doi:10.3109/08860229909066977
更新日期:1999-03-01 00:00:00
abstract:OBJECTIVE:To investigate the eradication rate of Helicobacter pylori with omeprazole, amoxicillin and clarithromycin during 6 days in patients with duodenal ulcer. To compare the reliability of the analysis of the eradication with urea-13C breath test performed one month and 3 months after therapy. To evaluate the one-...
journal_title:Renal failure
pub_type: 杂志文章
doi:10.3109/08860229909066987
更新日期:1999-03-01 00:00:00
abstract:PURPOSE:This article gives a general description of the incidence, causes, and complexity of maxillofacial fractures in the elderly and discusses whether modification is required in assessment, surgical indications, and techniques in such cases. PATIENTS AND METHODS:A retrospective clinical and radiologic study evalua...
journal_title:Renal failure
pub_type: 杂志文章,评审
doi:10.3109/08860229909085088
更新日期:1999-05-01 00:00:00
abstract:PURPOSE:This article gives a general description of the incidence, causes, and complexity of maxillofacial fractures in the elderly and discusses whether modification is required in assessment, surgical indications, and techniques in such cases. PATIENTS AND METHODS:A retrospective clinical and radiologic study evalua...
journal_title:Renal failure
pub_type: 杂志文章
doi:10.3109/08860229909085098
更新日期:1999-05-01 00:00:00
abstract:PURPOSE:This article gives a general description of the incidence, causes, and complexity of maxillofacial fractures in the elderly and discusses whether modification is required in assessment, surgical indications, and techniques in such cases. PATIENTS AND METHODS:A retrospective clinical and radiologic study evalua...
journal_title:Renal failure
pub_type: 杂志文章,评审
doi:10.3109/08860229909085108
更新日期:1999-05-01 00:00:00
abstract:OBJECTIVES:To reduce fires and fire related injuries by increasing the prevalence of functioning smoke alarms in high risk households. SETTING:The programme was delivered in an inner London area with above average material deprivation and below average smoke alarm ownership. The target population included low income a...
journal_title:Renal failure
pub_type: 杂志文章
doi:10.3109/08860229909045188
更新日期:1999-09-01 00:00:00
abstract:UNLABELLED:OBJECTIVES To assess over-the-counter antimicrobial dispensing by drug retailers in Kathmandu, Nepal, for rationality, safety, and compliance with existing government regulations. METHODS:Standardized cases of dysuria in a young adult male and acute watery diarrhoea in a child were presented by a mock patie...
journal_title:Renal failure
pub_type: 杂志文章
doi:10.3109/08860229909094154
更新日期:1999-11-01 00:00:00
abstract:UNLABELLED:OBJECTIVES To assess over-the-counter antimicrobial dispensing by drug retailers in Kathmandu, Nepal, for rationality, safety, and compliance with existing government regulations. METHODS:Standardized cases of dysuria in a young adult male and acute watery diarrhoea in a child were presented by a mock patie...
journal_title:Renal failure
pub_type: 杂志文章
doi:10.3109/08860229909094164
更新日期:1999-11-01 00:00:00
abstract::Robert Schumann, one of the giants of early romantic music, was born in Saxony in 1810 and died in an asylum shortly after his 46th birthday. Early in life, he demonstrated extraordinary skills in both music and journalism; he remained active in both areas until his final illness. His marriage to the remarkable pianis...
journal_title:Renal failure
pub_type: 杂志文章
doi:10.1081/jdi-100100853
更新日期:2000-01-01 00:00:00
abstract:BACKGROUND:Velopharyngeal insufficiency is an uncommon complication of adenoidectomy. Persistent velopharyngeal insufficiency following adenoidectomy (VIA) may occur in association with an unrecognized syndrome, such as velocardiofacial syndrome (VCFS). Although the diagnosis of VCFS is primarily a clinical one, a test...
journal_title:Renal failure
pub_type: 杂志文章
doi:10.1081/jdi-100100863
更新日期:2000-03-01 00:00:00
abstract::Salivary gland mucosa associated lymphoid tissue (MALT) type lymphomas are B-cell neoplasms that develop out of a reactive infiltrate, often associated with Sjögren's syndrome. Previous reports from our laboratory involving 10 patients suggested these lymphomas expressed a restricted immunoglobulin (Ig) V(H) gene repe...
journal_title:Renal failure
pub_type: 临床试验,杂志文章
doi:10.1081/jdi-100100876
更新日期:2000-05-01 00:00:00
abstract:UNLABELLED:Chronic bleeding from the gastrointestinal tract is assumed to be the most common cause of iron deficiency anemia in men and in postmenopausal women. AIM:The aim of this study was to assess the most frequent causes of chronic gastrointestinal bleeding in patients with iron deficiency anemia and to suggest a...
journal_title:Renal failure
pub_type: 杂志文章
doi:10.1081/jdi-100100887
更新日期:2000-01-01 00:00:00
abstract::Herpes zoster infections are frequently observed after allogeneic bone marrow transplantation (alloBMT). In the majority of cases, the infection is restricted to specific dermatomes and responds to oral acyclovir, without visceral dissemination. We report the case of a 40-year-old male who developed dermatomal herpeti...
journal_title:Renal failure
pub_type: 杂志文章
doi:10.1081/jdi-100100902
更新日期:2000-01-01 00:00:00
abstract::The Suppressor of forked protein is the Drosophila homolog of the 77K subunit of human cleavage stimulation factor, a complex required for the first step of the mRNA 3'-end-processing reaction. We have shown previously that wild-type su(f) function is required for the accumulation of a truncated su(f) transcript polya...
journal_title:Renal failure
pub_type: 杂志文章,评审
doi:10.1081/jdi-100101961
更新日期:2000-11-01 00:00:00
abstract:BACKGROUND:Tests developed to monitor glycoprotein (GP) IIb/IIIa blockade do not properly reflect platelet function in vivo and need a baseline (pretreatment) value. Because GP IIb/IIIa is essential in platelet aggregation and thrombosis under shear conditions, a flow-dependent approach to monitor its inhibition can be...
journal_title:Renal failure
pub_type: 杂志文章
doi:10.1081/jdi-100001287
更新日期:2001-01-01 00:00:00
abstract::A case of peripancreatic fat necrosis, after an episode of acute pancreatitis, which mimicked pancreatic cancer with lymph node metastases, is presented. We describe the imaging findings with helical CT scanning and with unenhanced and mangafodipir-enhanced MR imaging, with special emphasis on the differential diagnos...
journal_title:Renal failure
pub_type: 临床试验,杂志文章,随机对照试验
doi:10.1081/jdi-100103493
更新日期:2001-03-01 00:00:00
abstract::Catamenial hemoptysis is a rare condition, and only 36 cases have been reported since the first published case. We describe a woman with catamenial hemoptysis recurring over 8 years. The lesion was diagnosed using chest CT scan during menses and was also visualized clearly via thoracoscopy. The patient was treated suc...
journal_title:Renal failure
pub_type: 杂志文章
doi:10.1081/jdi-100104721
更新日期:2001-05-01 00:00:00
abstract::Catamenial hemoptysis is a rare condition, and only 36 cases have been reported since the first published case. We describe a woman with catamenial hemoptysis recurring over 8 years. The lesion was diagnosed using chest CT scan during menses and was also visualized clearly via thoracoscopy. The patient was treated suc...
journal_title:Renal failure
pub_type: 杂志文章
doi:10.1081/jdi-100104731
更新日期:2001-05-01 00:00:00
abstract::Catamenial hemoptysis is a rare condition, and only 36 cases have been reported since the first published case. We describe a woman with catamenial hemoptysis recurring over 8 years. The lesion was diagnosed using chest CT scan during menses and was also visualized clearly via thoracoscopy. The patient was treated suc...
journal_title:Renal failure
pub_type: 杂志文章
doi:10.1081/jdi-100104741
更新日期:2001-05-01 00:00:00
abstract::Genes with new functions often evolve by gene duplication. Alternative splicing is another means of evolutionary innovation in eukaryotes, which allows a single gene to encode functionally diverse proteins. We investigate a connection between these two evolutionary phenomena. For approximately 10% of the described cas...
journal_title:Renal failure
pub_type: 杂志文章
doi:10.1081/jdi-100107363
更新日期:2001-09-01 00:00:00
abstract::Genes with new functions often evolve by gene duplication. Alternative splicing is another means of evolutionary innovation in eukaryotes, which allows a single gene to encode functionally diverse proteins. We investigate a connection between these two evolutionary phenomena. For approximately 10% of the described cas...
journal_title:Renal failure
pub_type: 杂志文章
doi:10.1081/jdi-100107373
更新日期:2001-09-01 00:00:00
abstract:PURPOSE:To evaluate the efficacy of an intracapsular ring releasing 5-fluorouracil (5-FU) in preventing posterior capsule opacification (PCO) in rabbit eyes. SETTING:Center for Research on Ocular Therapeutics and Biodevices, Storm Eye Institute, Medical University of South Carolina, Charleston, South Carolina, USA, an...
journal_title:Renal failure
pub_type: 杂志文章
doi:10.1081/jdi-100108195
更新日期:2001-11-01 00:00:00
abstract:METHODS:We evaluated the postprandial lipid metabolism in patients with normolipemic peripheral arterial disease (PAD) after the administration of an oral fat load. Total cholesterol, low-density lipoprotein cholesterol (LDL-C), high-density lipoprotein cholesterol (HDL-C), HDL2 and HDL3 subfractions, triglycerides (TG...
journal_title:Renal failure
pub_type: 杂志文章
doi:10.1081/jdi-120002666
更新日期:2002-01-01 00:00:00
abstract:METHODS:We evaluated the postprandial lipid metabolism in patients with normolipemic peripheral arterial disease (PAD) after the administration of an oral fat load. Total cholesterol, low-density lipoprotein cholesterol (LDL-C), high-density lipoprotein cholesterol (HDL-C), HDL2 and HDL3 subfractions, triglycerides (TG...
journal_title:Renal failure
pub_type: 杂志文章
doi:10.1081/jdi-120002665
更新日期:2002-01-01 00:00:00
abstract::Mammalian eggs are arrested in metaphase II of meiosis until fertilization. Arrest is maintained by cytostatic factor (CSF) activity, which is dependent on the MOS-MEK-MAPK pathway. Inhibition of MEK1/2 with a specific inhibitor, U0126, parthenogenetically activated mouse eggs, producing phenotypes similar to Mos(-/-)...
journal_title:Renal failure
pub_type: 杂志文章
doi:10.1081/jdi-120004096
更新日期:2002-03-01 00:00:00
abstract::Neuroendocrine gut and pancreatic tumors have provided a diagnostic and therapeutic challenge over the years. Although they are considered slow growing, when disseminated their prognosis is poor. Currently, the various therapeutic options available for patients with inoperable GEP tumors aim either to control symptoms...
journal_title:Renal failure
pub_type: 杂志文章
doi:10.1081/jdi-120005360
更新日期:2002-05-01 00:00:00
abstract::Neuroendocrine gut and pancreatic tumors have provided a diagnostic and therapeutic challenge over the years. Although they are considered slow growing, when disseminated their prognosis is poor. Currently, the various therapeutic options available for patients with inoperable GEP tumors aim either to control symptoms...
journal_title:Renal failure
pub_type: 临床试验,杂志文章
doi:10.1081/jdi-120005370
更新日期:2002-05-01 00:00:00
abstract::Olfaction is of considerable importance to many insects in behaviors critical for survival and reproduction, including location of food sources, selection of mates, recognition of colony con-specifics, and determination of oviposition sites. An ubiquitous, but poorly understood, component of the insect's olfactory sys...
journal_title:Renal failure
pub_type: 杂志文章
doi:10.1081/jdi-120006770
更新日期:2002-07-01 00:00:00